Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112403498
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Entry
112403498 CDS
T08872
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
nasi
Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi00140
Steroid hormone biosynthesis
nasi00980
Metabolism of xenobiotics by cytochrome P450
nasi01100
Metabolic pathways
nasi05204
Chemical carcinogenesis - DNA adducts
Module
nasi_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
nasi00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
112403498 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
112403498 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
112403498 (HSD11B1)
Enzymes [BR:
nasi01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
112403498 (HSD11B1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
DUF1776
2-Hacid_dh_C
Pyr_redox_2
NAD_binding_2
Pyr_redox_3
Shikimate_DH
Methyltransf_25
Pyr_redox
Motif
Other DBs
NCBI-GeneID:
112403498
NCBI-ProteinID:
XP_024606764
UniProt:
A0A341BVP6
LinkDB
All DBs
Position
Unknown
AA seq
298 aa
AA seq
DB search
MAFMKKYLLPILGIFLAYYYYSAKEEFRPEMLRGKRVIVTGASKGIGREMAYHLARMGAH
VVVTARSEEALKKVVSHCLELGASSAHYVAGTMENMTFAEQFVAKAGKLMGGLDMLILNH
ITNTNNPMTVFIDDIDHVRKNMEVNFLSYVVLSGAAMPMLKQSNGSIVVVSSIAGKTANP
LIAAYSASKFALDGFFSSIRVEYAVTNVNVSITLCILGLIDTETAMTGTAGIYNAEASPK
EECALEIIKGGALRQKEVYYDSSVLTPFLLGNPGRKIMEFLSLRNYNMEIFINNQVLP
NT seq
897 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaagaaatatctcctccccattctggggatcttcttggcctactactac
tattctgcgaaggaggaattcagaccagagatgcttcgaggaaaaagagtgattgtcaca
ggggccagcaaggggattggaagagagatggcctatcatctggcgagaatgggagcccat
gtggtagtgacagcgaggtcagaagaagctctaaagaaggtggtatcccactgcctggag
ctcggtgcatcctcggcgcactacgttgctggcaccatggagaacatgaccttcgcagag
caatttgttgccaaagctggaaaactcatggggggactagacatgctcattctgaaccac
atcaccaacaccaacaaccctatgactgttttcatcgatgacattgaccacgtgcgcaaa
aacatggaggtcaacttcctgagttacgtggtcctgagcggggccgccatgcccatgctg
aagcagagcaacgggagcattgttgtcgtctcctcgatagccgggaaaacagctaatcca
cttattgctgcctattctgcaagcaagtttgctctggatgggttcttctcctctatcagg
gtggaatacgcagtgaccaatgtcaatgtgtcgatcaccctctgtatccttggcctcata
gacacagaaacagccatgacaggaactgctgggatatacaatgcagaagcatctccaaag
gaagaatgtgccctggagattatcaaagggggagctctgcgccaaaaggaagtatattat
gacagttcggtcttgactcctttcctgctgggaaatccggggaggaagatcatggaattt
ctctccttacgaaattataatatggaaatatttataaacaaccaggtacttccttag
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