Nocardia brasiliensis: O3I_015925
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Entry
O3I_015925 CDS
T02270
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
nbr
Nocardia brasiliensis
Pathway
nbr00010
Glycolysis / Gluconeogenesis
nbr00020
Citrate cycle (TCA cycle)
nbr00620
Pyruvate metabolism
nbr00785
Lipoic acid metabolism
nbr01100
Metabolic pathways
nbr01110
Biosynthesis of secondary metabolites
nbr01120
Microbial metabolism in diverse environments
nbr01200
Carbon metabolism
nbr01210
2-Oxocarboxylic acid metabolism
Module
nbr_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nbr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
O3I_015925
00020 Citrate cycle (TCA cycle)
O3I_015925
00620 Pyruvate metabolism
O3I_015925
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
O3I_015925
Enzymes [BR:
nbr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
O3I_015925
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Gene cluster
GFIT
Motif
Pfam:
Transketolase_N
Transketolase_C_1
PDH_E1_M
Transketolase_C
Transket_pyr
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AFU01146
UniProt:
K0F0E1
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Position
3554216..3556594
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AA seq
792 aa
AA seq
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MRSNTRMSFEEMPMTEVTEPEYKRGAAGLDALSEIERRTLWLAVSMIHHANRVRPNPSGL
KVGGHQASCASMTTIMTSLWFTALRSGDRVSVKPHASPVLHAINYLLGELDESYLTTLRQ
FGGLQSYPSRSKDPDPVDYSTGSVGIGATAPIWGAIARRYLNDALGADTGTGRQYSLVGD
AELDEGAVWEAVVDPGNADLGEIVWIVDLNRQSLDRVVPNIAAGRLEAMFAAAGWQVLTV
KFGRLLESLFARPGGAALRARILDMPNPEYQRLLRCDADELRRRLPGSGPDHAQLTELIA
GLDDSTLLAAIRNLGGHDMQALIEAYAQIDDTRPTVIIAYTIKGYGLPTQGHPQNHSSLL
SVAEYESLAAELGRDPQHPWARLNDDSAAGRLCAETALRLRREPVHSVEVPEVPKDFGHT
PKSIATTQAALGRTLLDLSRAAPEMARRVITVSPDVSSTTNLAGWINKVGVWSSAERHDW
FADDAETLVRWREQPTGRHMELGIAETNLVGLIGELGATWSRWGQPLFPIGVLYDPFVER
ALEPWTYGIYAGGQSILIGTPSGVTLAAEGGAHQSITTPSIGIETPGLICYEPAFAIDVE
WTLLASIARLGRPDGTSAYLRLSTRPVEQRLAEVPADPAARERRRKQVVAGGYPLRRRAD
AVVTIVAMGAVVTEAVAAADRLESGGVVADIVCVTSPGLLFEASQARQGRGHGDSWILDQ
LFPPSRATPMVTVLDGHPHTMSFLSGINRVHHIDLGVTRYGQVGSLEEVYRYHGLDADSI
VAAALDVLGAAG
NT seq
2379 nt
NT seq
+upstream
nt +downstream
nt
atgcggtcgaacacccggatgtcattcgaggagatgccgatgaccgaggtcaccgagccg
gaatacaagcgcggcgccgccgggttggacgccctatcggagatcgagcgtcgcacgttg
tggctggcggtttcgatgattcatcacgccaaccgggttcggccgaatccgtcggggttg
aaggtgggcgggcatcaggcctcgtgcgcgtcgatgaccaccatcatgacttcgctgtgg
ttcaccgctttgcgctccggtgaccgggtttcggtcaaaccgcatgcgtcgccggtgctg
cacgccatcaactatctgctgggggagttggacgagtcgtacctgaccacgttgcgtcaa
ttcggtggcctgcagtcctatcccagccggtccaaggaccctgatccggtcgactattcg
accggatcggtcgggatcggggcgaccgcgccgatctggggtgcgatcgcgcggcgctat
ctcaacgacgcgctgggtgccgataccggtaccggtcggcagtattcgctggtcggtgat
gcggagttggacgagggggcggtgtgggaggccgtcgtcgatcccggtaacgccgatctc
ggtgagatcgtgtggatcgtcgatctgaaccgtcagtccctggaccgggtggtgcccaat
atcgctgccggtcggctggaggcgatgttcgccgccgcgggctggcaggtgctcacggtg
aagttcgggcgtctgctggaatcgttgttcgctcggccgggtggcgccgcgctgcgcgcc
cggatcctcgacatgcccaaccctgagtaccagcgtctgctgcgctgcgacgccgacgaa
ctacggcgcaggctgccgggcagcggacctgaccatgcgcaattgacggaattgattgca
ggtctggatgattcgacactcttggcggcgatccgcaatctaggtgggcacgatatgcag
gccttgatcgaggcctacgcccagatcgacgacacccgtccgacggtgatcatcgcctac
accatcaaaggctatgggctgccgacacaaggacatccgcagaaccattcgtcgctgctg
tcggtggccgagtacgaatcgctcgccgccgaactcggccgcgatccacagcacccgtgg
gcgcggctcaacgacgacagcgcggccggacgattatgcgcggagaccgcgctgcggttg
cgtcgcgaaccggtgcattcggtcgaagtacccgaggtaccaaaggatttcggccataca
ccgaaaagtatcgcgaccacgcaggcggcgctggggcggactctgctggacctgagccgg
gcggcgccggagatggcgcggcgggtgatcaccgtgagtcccgacgtcagctccaccacc
aatctggcgggctggatcaacaaggtcggtgtgtggtcgagcgccgaacggcacgactgg
ttcgccgacgacgccgaaacgctcgtgcggtggcgtgagcaacccaccggtcggcacatg
gaactcggtatcgccgaaacgaatctggtcgggctgatcggcgaactcggcgcgacctgg
agccggtggggccaacccctgttcccgatcggtgtgctctacgacccgttcgtcgaacgc
gcgctcgaaccctggacctacggcatctacgccggcgggcagtcgatcctgatcgggacg
ccgtccggtgtcaccctcgccgccgaaggtggtgcccaccaatcgattacgacgccctcg
atcggtatcgagacgccgggcctgatctgttacgaacccgcgttcgccatcgacgtggaa
tggacgctgctggccagtatcgcccggctcgggcgaccggacgggacctcggcgtatctg
cggctgtcgacccggccggtcgaacagcgcctcgccgaggtgcccgccgaccctgccgcg
cgggagcgtcgtcgcaaacaggtggtggcaggcggatatccgctgcgccggcgcgcggac
gcggtcgtcacgatcgtcgcgatgggcgccgtggtgaccgaggcggtggccgcggccgac
cggctcgaatcgggcggggttgtcgccgacatcgtgtgcgtcaccagtcccgggctgctc
ttcgaggcatcgcaggccaggcaaggccgcggccacggggacagctggatcctggatcag
ctgttcccgcccagccgggccacgccgatggtgaccgtgctggacggccacccgcacacc
atgtctttcctgtccgggatcaatcgggtgcatcacatcgatctcggcgtgacgcgttac
gggcaagtcggatcgctcgaggaggtgtaccgctaccacgggttggacgccgacagcatt
gtcgccgccgccctcgacgtgctcggcgcggccggttga
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