KEGG   Nocardioides sp. JS614: Noca_2631
Entry
Noca_2631         CDS       T00443                                 
Name
(GenBank) methionine synthase (B12-dependent)
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
nca  Nocardioides sp. JS614
Pathway
nca00270  Cysteine and methionine metabolism
nca00450  Selenocompound metabolism
nca00670  One carbon pool by folate
nca01100  Metabolic pathways
nca01110  Biosynthesis of secondary metabolites
nca01230  Biosynthesis of amino acids
nca04980  Cobalamin transport and metabolism
nca04981  Folate transport and metabolism
Module
nca_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:nca00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Noca_2631
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Noca_2631
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Noca_2631
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Noca_2631
   04980 Cobalamin transport and metabolism
    Noca_2631
Enzymes [BR:nca01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Noca_2631
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding RoxA-like_Cyt-c PA KH_GLD-3_3rd
Other DBs
NCBI-ProteinID: ABL82134
UniProt: A1SJZ9
LinkDB
Position
2798981..2802715
AA seq 1244 aa
MSWSPQQRPDLTDQLTRALEQRILVLDGAMGTAIQRDRPDEAGYRGERFADWPSDLVGNN
DLLTITRPEIIAGIHREYLLAGADIIETNTFNANAVSLSDYGMQELAYEINYEAAQLARR
EVDAVSTQEHPRYVAGALGPTTRTASISPDVNDPGARNVTYDQLVAAYLDAARGLVDGGA
DLLVIETIFDTLNAKAAIFAVETLFAENQRRWPVIISGTITDASGRTLSGQVTEAFWNSV
RHARPLAVGLNCALGAKEMRPYIAEIARIADTFVSCYPNAGLPNAFGEYDEAAEETAAII
EEFAASGFVNLVGGCCGTTPAHVAAIAKAVEGKTRRPVPELTPALRLAGLEPFAVTDKSL
FVNVGERTNITGSARFRKLIKDGDYDTALSVAAQQVENGAQVIDINMDEGMIDGVAAMDR
FTRLIASEPDISRVPVMVDSSKWEVIQAGLKNIQGKPIVNSISMKEGEDTFREQARLCRQ
YGAAAVVMAFDEDGQADNLERRKAICERAYRILVDEVGFPPEDIIFDPNVFAVATGIEEH
ASYGLDFIEATRWIKQNLPGAKVSGGISNVSFSFRGNNPVREAIHAVFLYHAIGAGLDMG
IVNAGALVVYDQVEPELRERIEDVILNRRPDAAERLLEIAEAHNRAGETTEAAAAEEWRA
LPVEERITHALVKGIDAHVEPDTEELRQLIAARGGRPIEVIEGPLMDGMNVVGDLFGAGK
MFLPQVVKSARVMKKAVAYLIPFIEQEKLDNPELATAKETNGTIVMATVKGDVHDIGKNI
VGVVLQCNNYEVIDLGVMVPTQKLLDTALEVGADAVGVSGLITPSLDEMVGVAAEMQRRG
MEIPLLVGGATTSRAHTAVKVDGKYDGPVVWVKDASRSVPTLATLLNPAQRPRLMAEIKE
DYDSLRARHATKHDRPMLTLEQARDNRTPIDWSTYAPPAPRTPGIHVLEDYDLAELRDFI
DWQPFFNAWELKGKFPDILNSPTTGETARGLYDDAQAMLDRVIEEKWLRANAVFGLFPAN
AVGDDVEVYTDDSRTEVLTTLHNLRQQGDHRDGIPNRSLGDFVAPRATGLPDHVGAFAVT
AGLGAEARILEFKEQLDDYSAIMLEALADRLAEAFAERLHQRVRTEFWAHAPEEDLDNQA
LIAERYDGIRPAPGYPACPEHTEKRTLWRLLDVTARTGIELTDGMAMWPGAAVSGWYYSH
PQSQYFVLGRIGRDQVADYAERKGWTLTEAERWLSPNLGYDPDD
NT seq 3735 nt   +upstreamnt  +downstreamnt
ttgtcctggtccccccagcagcgccccgacctgaccgaccagctgacgcgcgctctggag
cagcgcatcctggtgctcgacggcgcgatgggtacggcgatccagcgggaccgacccgac
gaggcgggctatcgcggcgagcggttcgccgactggcccagcgacctcgtgggcaacaac
gacctgctgacgatcacccggccggagatcatcgcgggcatccaccgcgagtacctcctc
gccggcgccgacatcatcgagacgaacacgttcaacgccaacgcggtctcactgtccgac
tacggcatgcaggagctggcctacgagatcaactacgaggcggcgcagctcgcccggcgc
gaggtcgatgcggtcagcacgcaggagcatccgcgctacgtcgccggcgcactgggcccg
accacccgcacggcctcgatctcgcccgacgtcaacgacccgggcgcgcgcaacgtgacc
tacgaccagctggtcgcggcgtacctcgacgcggcccgcggcctcgtcgacggcggtgcc
gacctgctcgtgatcgagacgatcttcgacaccctcaacgcgaaggccgcgatcttcgcg
gtcgagacgctcttcgccgagaaccagcgccgctggccggtcatcatctccggcacgatc
accgacgcctcggggcgcaccctctccggtcaggtcaccgaggcgttctggaactccgtg
cgccacgcccggccgctggcggtcggcctcaactgcgcgctcggcgcgaaggagatgcgg
ccctacatcgccgagatcgcccggatcgcggacaccttcgtctcctgctacccgaacgcg
ggcctgcccaacgccttcggcgagtacgacgaggccgccgaggagacggccgcgatcatc
gaggagttcgccgccagcggcttcgtgaacctggtcggcggctgttgcggcacgacccct
gcccacgtcgcggccatcgcgaaggcggtcgagggcaagacccggcggcccgtccccgag
ctgacgccggcgctgcggctggccggcctcgagccgttcgcggtgaccgacaagagcctg
ttcgtcaacgtgggggagcgcacgaacatcacgggctcggcccggttccgcaagctgatc
aaggacggcgactacgacaccgcgctgagcgtggccgcgcagcaggtggagaacggcgcg
caggtcatcgacatcaacatggacgagggcatgatcgacggggtggcggcgatggaccgc
ttcacccgcctgatcgcgagcgaaccggacatcagtcgggtcccggtgatggtcgactcc
tccaagtgggaggtcatccaggcgggcctgaagaacatccagggcaagccgatcgtcaac
tcgatctccatgaaggagggcgaggacacgttccgcgagcaggcgcggctgtgccgtcag
tacggcgcggccgcggtcgtgatggccttcgacgaggacggccaggccgacaacctggag
cggcgcaaggcgatctgcgagcgcgcctaccggatcctggtcgacgaggtcggcttcccg
cccgaggacatcatcttcgaccccaacgtgttcgccgtcgcgaccggcatcgaggagcac
gcgtcgtacgggctggacttcatcgaggccacccgctggatcaagcagaacctcccgggc
gccaaggtctcgggcggcatctccaacgtgagcttctccttccgcggcaacaacccggtc
cgcgaggcgatccacgccgtgttcctgtaccacgcgatcggcgccgggctcgacatgggc
atcgtcaacgcgggcgcgctcgtcgtctacgaccaggtcgagcccgagctgcgggagcgg
atcgaggacgtcatcttgaaccggcgacccgacgccgccgagcggctcctggagatcgcc
gaggcccacaaccgggccggcgagaccaccgaggccgccgccgccgaggagtggcgcgca
ctgccggtcgaggagcggatcacccacgcgctcgtcaagggcatcgacgcgcacgtcgag
ccggacaccgaggagctgcggcagctgatcgccgctcgcggcggacgcccgatcgaggtc
atcgagggcccgctgatggacggcatgaacgtcgtcggcgacctgttcggcgccgggaag
atgttcctgccccaggtcgtgaagtcggcgcgcgtcatgaagaaggcggtcgcctacctg
atccccttcatcgagcaggagaagctggacaaccccgagctcgcgacggccaaggagacc
aacggcacgatcgtgatggcaacggtgaagggcgacgtccacgacatcggcaagaacatc
gtcggcgtcgtgctgcagtgcaacaactacgaggtcatcgacctcggcgtgatggtgccc
acccagaagctcctggacacggccctcgaggtcggcgccgacgccgtcggcgtctccggc
ctgatcaccccctcgctggacgagatggtcggggtggccgccgagatgcagcgccggggc
atggagatcccgctgctggtcggcggcgcgaccacctcacgggcacacacggccgtgaag
gtcgacggcaagtacgacggacccgtcgtctgggtcaaggacgcctcgcgctcggtcccg
accctggcgacgctgctgaacccggcgcagcgtccgcggctgatggccgagatcaaggag
gactacgactccctgcgggcccggcacgccacgaagcacgaccgcccgatgctgaccctc
gagcaggcccgggacaaccgcaccccgatcgactggtcgacgtacgcgcccccggcgccg
cgaaccccgggcatccacgtcctcgaggactacgacctcgccgagctgcgcgacttcatc
gactggcagccgttcttcaacgcctgggagctgaaggggaagttccccgacatcctcaac
agtccgaccaccggggagaccgcacgcgggctgtacgacgacgcgcaggcgatgctcgac
cgggtcatcgaggagaagtggctgcgggccaatgccgtgttcgggctgttcccggcgaac
gcggtcggtgacgacgtcgaggtctacaccgacgactcgcgcaccgaggtgctgaccacg
ctgcacaacctgcgccagcagggcgaccaccgcgacggcatccccaaccggtccctgggg
gacttcgtggcgccgcgggcgaccgggcttcccgaccacgtcggggccttcgcggtcacc
gccggcctcggggcggaggccaggatcctggagttcaaggagcagctcgatgactactcc
gcgatcatgctcgaggcactggccgaccggctcgccgaggccttcgccgagcggttgcac
cagcgggtgcgcaccgagttctgggcccatgctcccgaggaggacctcgacaaccaggcc
ctgatcgcggagcggtacgacggcatccggcccgcgcccggctaccccgcctgcccggag
cacaccgagaagcgcaccctgtggcggctgctcgacgtgacggcgcggaccggcatcgag
ctgaccgacgggatggcgatgtggcccggcgccgccgtctccggttggtactacagccac
ccgcagtcgcagtacttcgtgctcggccggatcggccgtgaccaggtggccgactacgcc
gagcggaagggctggacgctcacggaggccgagcggtggctctcgcccaacctcggctac
gacccggatgactga

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