Sciurus carolinensis (gray squirrel): 124968393 Help Entry 124968393         CDS       T08117                                  Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism ncar  Sciurus carolinensis (gray squirrel) Pathway ncar04010   MAPK signaling pathway ncar04014   Ras signaling pathway ncar04015   Rap1 signaling pathway ncar04022   cGMP-PKG signaling pathway ncar04066   HIF-1 signaling pathway ncar04068   FoxO signaling pathway ncar04072   Phospholipase D signaling pathway ncar04081   Hormone signaling ncar04150   mTOR signaling pathway ncar04151   PI3K-Akt signaling pathway ncar04152   AMPK signaling pathway ncar04211   Longevity regulating pathway ncar04213   Longevity regulating pathway - multiple species ncar04520   Adherens junction ncar04910   Insulin signaling pathway ncar04913   Ovarian steroidogenesis ncar04923   Regulation of lipolysis in adipocytes ncar04930   Type II diabetes mellitus ncar04931   Insulin resistance ncar04932   Non-alcoholic fatty liver disease ncar04960   Aldosterone-regulated sodium reabsorption ncar05010   Alzheimer disease ncar05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:ncar00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     124968393    04014 Ras signaling pathway     124968393    04015 Rap1 signaling pathway     124968393    04066 HIF-1 signaling pathway     124968393    04068 FoxO signaling pathway     124968393    04072 Phospholipase D signaling pathway     124968393    04022 cGMP-PKG signaling pathway     124968393    04151 PI3K-Akt signaling pathway     124968393    04152 AMPK signaling pathway     124968393    04150 mTOR signaling pathway     124968393   09133 Signaling molecules and interaction    04081 Hormone signaling     124968393  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     124968393  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     124968393    04923 Regulation of lipolysis in adipocytes     124968393    04913 Ovarian steroidogenesis     124968393   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     124968393   09149 Aging    04211 Longevity regulating pathway     124968393    04213 Longevity regulating pathway - multiple species     124968393  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     124968393   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     124968393   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     124968393    04932 Non-alcoholic fatty liver disease     124968393    04931 Insulin resistance     124968393  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ncar01001]     124968393   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:ncar04090]     124968393 Enzymes [BR:ncar01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      124968393 Protein kinases [BR:ncar01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    124968393 CD molecules [BR:ncar04090]  Proteins   124968393 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like B2 DUF4476 Motif Other DBs NCBI-GeneID:  124968393 NCBI-ProteinID:  XP_047386690 LinkDB All DBs Position 17:complement(4497013..4629969) Genome browser AA seq 1381 aa AA seqDB search MGAGGRRGAAAAPLLVAVAALLVGAAGHLFPGEVCPGMDIRNNLTRLHELENCSVIEGHL QILLMFKTRPEDFRDLSFPKLIVITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTSCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNRCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSFIKTSFDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPQRSNDPKPQHHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWE RQEEDSELYELDYCLKGLKLPSRTWSPPFESEDAQKHNQSEYEDSAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRKTSSGSGTEDPRPSRKRRSLGLVENVTELAPTALVL PSSAPSEPASQEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYVS ARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPREPNGLIVLYEVSYRRYGDEELHLCVS RKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGP LIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPRE KITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNEAASLRERIEFLNEASVMKGF TCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEVIQMAA EIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVR WMAPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLEQPDNC PDTVTELMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESEELEMEF EDMENVPLDRSSHCQREEAGGREGGSSLGIKRNYEEHIPYTHMNGGKKNGRILTLPRSSP S NT seq 4146 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgggggccggcggggggcggcggccgcgccgctgctggtggccgtggccgcg ttgctggtgggcgccgcgggccacctgttcccgggagaggtgtgtcccggcatggatatc cggaacaacctcaccaggctgcacgaactggagaactgctcggtcatcgaaggacacctg cagatcctgctgatgttcaaaaccaggcccgaggacttccgggacctcagtttccccaag ctgatcgtcatcaccgactacctgctgctcttccgggtctacgggctggagagcctgaag gacctgttccccaacctcaccgtcatccgcggctcccgcctcttcttcaactacgcgctg gtcatcttcgagatggtgcacctgaaggagctggggctctacagcctcatgaacatcacc cggggctccgtgcgcatcgagaagaacaacgagctctgctacctggccaccatcgactgg tcgcggatcctggactccgtggaggacaactacatcgtgctgaacaaggacgacaacgaa gaatgcggggacatctgcccgggcaccgccaagggcaagaccagctgccccgccaccgtc atcaacgggcagtttgtggagcgctgctggacgcacagccactgccagaaagtttgcccg accatctgtaagtcgcacggctgcaccgccgaagggctctgctgtcacagcgagtgcttg ggcaactgctccgagcccgacgaccccaccaagtgcgttgcctgccgcaacttctacctg gacggccggtgcgtggagacctgcccgcccccctactaccacttccaagactggcgctgt gtgaacttcagcttctgccaggacctgcacaacagatgcaagaactcacggaggcagggc tgccaccagtacgtcattcacaacaacaaatgtatccccgaatgtccttccgggtacacc atgaattccagcaacttgatgtgcaccccatgcctgggcccctgtcccaaggtctgtcac cttctagaaggcgagaagaccatcgactccgtgacgtcggcccaggagctgcgcggctgc accgtagtcaacgggagcctgatcatcaacattcgagggggcaacaacctggctgctgag ctggaggccaaccttggcctcattgaagaaatttcagggtatctgaaaatccgccgatcc tacgctctggtgtccctgtccttcttccggaagttgcgtttgattcgaggagagacgctg gagatcgggaactactctttctacgccttggacaaccagaacctcaggcagctctgggac tggagcaagcacaacctcaccatcactcaggggaaactcttcttccactataaccccaaa ctctgcttgtcggaaattcacaagatggaagaagtttccggaaccaagggacgccaggag aggaatgacatcgccctgaagaccaacggggaccaggcatcttgtgaaaatgaattactt aaattttctttcattaagacatctttcgacaagatcttgctgaaatgggagccatactgg ccccctgacttccgggacctcttaggattcatgctcttctacaaagaggccccttaccag aacgtgaccgagttcgacgggcaggatgcatgtggctccaacagctggaccgtggtggac attgacccgcctcagagatccaacgaccccaagccccagcaccaccctgggtggctgatg cggggtctcaagccctggacccagtacgccatcttcgtcaagaccttggtcaccttttct gatgagcgtcggacctacggggccaagagcgacatcatctacgtgcagacggacgccacc aatccttccgtccccctggatcccatctcggtctctaactcctcgtctcagatcattttg aagtggaagcccccctcggaccccaacggcaacatcacacactacctggtgtactgggaa aggcaggaggaagacagcgagctctacgagttggattactgtctcaaaggtctgaagctg ccctcgcgcacatggtccccgcccttcgagtccgaggatgctcagaagcacaatcagagc gagtacgaggattcggccggggaatgctgctcctgccccaagacggactctcagatcctg aaggagctggaggagtcctccttccggaagaccttcgaggattacctgcacaatgtggtt ttcgtccccagaaaaacctcttcaggcagtggtaccgaggatcctaggccgtctcggaag cgcaggtcccttggcctggtggagaacgtgacggagctggcgcccacggccctggttctc cccagcagcgcccccagcgagccggccagccaggaggagcacaggccctttgagaaggtg gtgaacaaggagtcgctggtcatctcgggcctgcgccacttcaccggctaccgcatcgag ctgcaggcctgcaaccaggacgcccccgaggagaggtgcagcgtggccgcctacgtcagc gcgcgcaccatgcccgaagccaaagcggatgacatcgtcggacctgtgacccacgagatc ttcgagaacaacgtcgttcacctgatgtggcaagagcccagggaacccaatggtctgatc gtgctgtacgaagtgagctaccggcgctacggcgacgaggagctgcatctctgtgtctcc cggaagcactttgctctggagaggggctgcaggctgcgtgggctgtcaccaggcaactac agcgtgcgcgtccgggccacgtccctggcaggcaacggctcctggacagaagccacctat ttctacgtgacagattatctagacgttccatcaaatattgcaaaaatcatcatcggtccc ctcatctttgtctttctcttcagcgttgtgattggaagcatttacctattcctgcggaaa aggcagccagatgggcctatgggacctctctacgcttcttccaaccctgagtacctcagt gccagtgacgtgtttccctcttccgtgtacgtgccggacgagtgggaggtgcctcgagag aagatcaccctcctgcgagagctggggcagggctccttcggcatggtgtacgagggtaat gccagggacatcgtcaaaggcgaggcggagacccgggtggccgtgaagaccgtcaacgag gcagccagtctccgggagcggatcgagttcctcaatgaggcctcggtcatgaagggcttc acctgccatcatgtggtccgcctcctgggagtggtgtccaagggccagcccacgctggtg gtgatggagttgatggcccacggagacctgaagagctacctccgctctctgagaccggag gctgagaacaatcccggtcgccctccccctaccctgcaagaggtgattcagatggcagca gaaatcgcagacgggatggcgtacttgaatgccaagaagttcgtgcaccgggacctggca gctcgaaactgcatggttgctcacgatttcactgtcaaaattggagattttggaatgacc agagacatctacgaaacggattactaccggaaaggcggcaagggcctgctgcccgtgcgg tggatggcacccgagtccctgaaggacggggtcttcactgcttcttccgacatgtggtcc ttcggtgtggtcctctgggagatcaccagcctggcagagcagccttaccaaggcctgtct aacgagcaggtgctgaagttcgtcatggatggcgggtacctggagcagcccgacaactgt ccggatacagtcaccgaactgatgcgcatgtgctggcagttcaaccccaagatgcggccc accttcctggagatcgtcaacctgctcaaggatgacctgcaccccagctttccagaggtg tccttcttccacagcgaggagaacaaggctcccgagagtgaggagctggagatggagttt gaggacatggagaatgtgcccttggatcggtcctcccactgtcagagggaggaggccggg ggccgggagggagggtcctcgctgggcatcaagcggaactatgaggagcacatcccctac acccacatgaatgggggcaagaagaacgggcggattctgaccttgccgcgctccagccct tcctaa

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