Sciurus carolinensis (gray squirrel): 124976070
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Entry
124976070 CDS
T08117
Name
(RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
ncar
Sciurus carolinensis (gray squirrel)
Pathway
ncar04120
Ubiquitin mediated proteolysis
ncar04144
Endocytosis
ncar04330
Notch signaling pathway
ncar04668
TNF signaling pathway
ncar04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
ncar00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
124976070
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
124976070
04668 TNF signaling pathway
124976070
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
124976070
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
124976070
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ncar04131
]
124976070
04121 Ubiquitin system [BR:
ncar04121
]
124976070
Enzymes [BR:
ncar01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
124976070
Membrane trafficking [BR:
ncar04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
124976070
Ubiquitin system [BR:
ncar04121
]
Ubiquitin ligases (E3)
HECT type E3
124976070
BRITE hierarchy
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Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
124976070
NCBI-ProteinID:
XP_047394675
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Position
2:complement(23097002..23221622)
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AA seq
860 aa
AA seq
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MSDSGLQIGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVIVTL
QLAGDKEPTETMGDLSICLDGLQLEAEVVTNGETTCSESASQNDDGSRPKDETRVNASGS
DDPEDAGSGENRRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPHRPASVNGXPSATSESD
GSSTGSLPPTNTNTSEGATSGLIIPLTISGGSGPRPLNPVTQXPLPPGWEQRVDQHGRVY
YVDHVEKRTTWDRPEPLPPGWERRVXQYGTYYYVDHFTRTTTWQRPTLESVRNYEQWQLQ
RSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRI
TQWEDPRNQGQLNEKPLPEGWEMRFTVDGIPYFVDHNKRTTTYIDPRTGKSALDNGPQIA
YVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPG
EEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGR
FIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEM
YFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNE
ILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNEK
RMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSY
EQLKEKLLFAIEETEGFGQE
NT seq
2583 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggattacaaattggttcaatgggtagcttgaccatgaagtcacaactt
cagatcactgtcatctcagcaaaacttaaagaaaataaaaagaactggtttggaccaagt
ccttatgtggaagtcacagtggatggacagtcaaaaaagacagaaaaatgcaacaatacc
aacagccccaaatggaagcaaccccttacagttatcgttacccctgtgagtaaattacac
tttcgagtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatttatgagacattaaagtcaaacaatatgaaacttgaagaagttattgtgactttg
cagcttgcaggtgacaaagagccaacagagacaatgggagacttgtcaatttgtcttgat
gggctgcagttagaagctgaagttgttactaatggtgaaactacatgttcagaaagtgct
tcacagaatgatgatggctccagacccaaggacgaaacaagagtgaacgcaagtggatca
gatgaccctgaggatgcagggtctggtgaaaatagaagagtcaatgggaacaattctcca
tcactctcaaatggtggttttaaaccttctagaccgccaagaccttcacgaccacctcca
cccactccacatagaccagcatctgtcaatggtncaccatctgccacttctgaaagtgat
ggatctagtacaggttctctgccaccaacaaatacaaatacatctgaaggagcaacatct
ggattaataattcctcttactatatctggaggctcaggccctaggccattgaatcctgta
actcagnctcccctaccacctggttgggagcaaagagtggaccagcatgggcgagtttat
tatgtagatcatgttgaaaaaagaacaacgtgggatagacctgagcctctacctcctggt
tgggaacggcgggtgnnacaatatgggacgtattattatgttgaccatttcacaagaaca
acaacatggcagaggccaacactggaatccgtccggaactacgaacagtggcagctacaa
cgtagtcagcttcaaggagcaatgcagcagtttaaccagagattcatttatggaaatcaa
gatttgtttgctacatcacaaaataaagaatttgatccccttggtcctttgccacctgga
tgggagaagagaactgatagcaatggcagagtatattttgtcaaccacaacactcgaatt
acacaatgggaagaccccagaaatcaaggtcagttaaatgaaaaacccttacctgaaggc
tgggaaatgagattcacagtggatggaattccatattttgtagaccacaataaaagaaca
actacctatatagatccccgcacaggaaaatctgccctagacaatggaccccaaatagcc
tatgttcgggacttcaaggcaaaggttcaatatttccgattctggtgtcagcaattggcc
atgccacagcacataaagattacagtaacaagaaaaacattgtttgaggattcctttcaa
cagataatgagcttcagtccacaagatctgcgaagacgtttgtgggtgatttttccagga
gaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtcgcatgaa
gttttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgcctgcag
ataaaccctgcttcttacatcaatccagatcacctgaaatactttcgtttcattggcagg
tttattgccatggctctgttccatgggaaattcatagacacaggtttttctttaccattc
tataaacgtatcttgaacaaaccagttggacttaaggatttagaatctattgatccagaa
ttttacaattctctcatctgggttaaagaaaacaatattgaagaatgtggtttggaaatg
tatttctccgttgataaagaaattctaggtgaaattaagagtcatgacttgaaacccaat
ggcggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggtagctgag
tggcggttatctcgaggtgttgaggaacagacacaagctttctttgagggctttaatgaa
attcttccccagcaatatttgcaatactttgatgcaaaggaactagaggtccttttatgt
ggaatgcaagagattgatttaaatgactggcaaagacatgcaatctaccgtcattacact
aggacaagcaaacaaatcatgtggttttggcagtttgttaaggaaattgataatgagaag
agaatgagacttctgcaatttgttactggaacctgccgattaccagtaggaggatttgca
gatctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaagaaaat
tggttacccagaagtcatacctgttttaaccgcctggaccttccaccctacaaaagctat
gagcaactgaaggaaaagttgttgtttgccattgaagaaacagaaggatttggacaagag
taa
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