Sciurus carolinensis (gray squirrel): 124979056
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Entry
124979056 CDS
T08117
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12 isoform X1
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
ncar
Sciurus carolinensis (gray squirrel)
Pathway
ncar00590
Arachidonic acid metabolism
ncar01100
Metabolic pathways
ncar01523
Antifolate resistance
ncar04726
Serotonergic synapse
ncar04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
ncar00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
124979056
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
124979056
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
124979056
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
124979056
Enzymes [BR:
ncar01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
124979056
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
124979056
NCBI-ProteinID:
XP_047399193
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Position
3:complement(52676560..52689661)
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AA seq
670 aa
AA seq
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MGRYRIRVATGAWLFSGSHNCVQLWLVGEHGEAELELQLRPVRGEEEEFVLDIPEDLGTL
QFVKLRKQHSLVDDAWFCERITVQSPGTSTETEFPCYRWVQGTGVLSLPEGTARLAGDNA
LDVFQKHREKEVKERQQIYCWATWKEGLPLTIAANCKDDLPPNMRFHEEKRLDFEWALKA
GALEMVLKRVYTLLSHWNRLEDFDQIFWGQKSSLAEKIHQCWQDDDLFGYQFLNGANPML
LRRSTSLPSRLVLPSGTEELQARLEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL
VMLKMEPNGKLLPMVIQIQPPNPSFPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHQLQYH
LLNTHLVAEVIAVATMRCLPGLHPVFKLLVPHIRYTMEINTRARTQLISDGGIFDQPCQL
LSQAASTGGGGHVQLLHRAVNKLTYSSLCPPDDLADRGLLGIPSALYAHDALQLWEIIAR
YVAGIIQLFYQRDDVVSGDPELQAWCREITEVGLCQAQDRGFPLSLQSQAQLCHFLTMCV
FTCTAQHGAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTLATVMGSLPDIRQSCLQMTI
TWHLGRRQPDMVPLGHHKEEYFSDPKAKAVLSQFQTDLENLEKEITARNKQLDLPYEYLK
PSRIENSVTI
NT seq
2013 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatccgcgtggccaccggagcttggctcttctcggggtcacacaac
tgcgtgcagctgtggctggtcggggagcacggggaagcggagctggagctacagctgcgg
cccgtgcggggcgaggaggaggagtttgttctggacattccggaggacctaggcacactg
caattcgtgaaactgcgcaaacagcactcactggtggacgatgcgtggttctgcgagcgc
atcacggtgcagagtcccggaaccagcacagagaccgagttcccgtgctaccgctgggtg
caaggcacaggcgtcctgagcctgcccgagggcactgcccgcctggcaggagacaatgcc
ttggatgtcttccagaagcatcgagaaaaggaagtgaaggaaagacaacagatctactgc
tgggctacttggaaggaagggctacccctgacaatagctgcaaactgtaaggatgaccta
cctccaaatatgagattccatgaggagaagaggctagacttcgaatgggcactgaaggca
ggggctctggagatggtcctcaaacgtgtttacaccctcctgagtcactggaaccgcctg
gaagactttgatcagatcttctggggccagaagagttccctggctgagaagatccaccag
tgctggcaggacgatgacctttttggctaccagttcctcaatggtgccaaccccatgctg
ttgagacgctctacctctctgccctccaggctggtgctgccctcagggacagaggaactt
caggctcggttggagaaggaactccagaatggttccctgtttgaggctgattttatcctg
ctggatggaattccagccaatgtgattcgaggagagaaacagtaccttgctgcccctctt
gtcatgttgaagatggaacccaatgggaagctgttacccatggtcatccagattcaacct
cccaatcccagcttcccaactccaacactgttcctgccatcagatcctccacttgcctgg
ctcctggccaagtcctgggttcgaaattcagatttccaactgcaccagctccaatatcat
ttgctgaacactcatttggtggctgaggtcatcgctgttgccaccatgaggtgcctacca
ggactgcaccctgttttcaagctcctggtcccccatatccgctacactatggaaatcaat
acccgggcccggacccagctcatttcagatggaggaatatttgatcagccttgtcaactc
ttgtctcaggcagcaagcacaggtggcgggggccatgtgcagttgcttcatcgggcagtg
aataagttgacctacagttccctgtgtcctcctgatgacctggctgaccggggccttctg
ggaatcccaagtgccctctatgcccatgatgctttacagctttgggagatcattgcccgg
tacgtggcagggatcatccaactcttctaccagagggatgatgttgtgagcggggatcct
gagttgcaggcctggtgtcgagagatcacggaggtggggctgtgccaggcccaggacaga
ggtttccctctctctctccagtcccaggctcaactatgccatttccttaccatgtgtgtc
ttcacatgcactgcccagcatggggccatcaaccagggtcagctggactggtatgcctgg
gtccctaatgccccttgcacaatgcggatgcccccacccaccaccaaggaagatgtgaca
ttggccacggtgatggggtcactacctgatatccggcagtcctgtcttcaaatgaccatc
acatggcatctgggtcgccgccagccagacatggtacctctggggcatcacaaagaagaa
tatttctcagaccccaaggctaaagctgtcctgagccaattccaaacagatctggaaaac
ctggaaaaagagattacagctcggaataagcaacttgacctgccttatgaatacctgaag
cccagtcgcatagaaaacagtgtcactatctga
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