Sciurus carolinensis (gray squirrel): 124979751 Help Entry 124979751         CDS       T08117                                  Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism ncar  Sciurus carolinensis (gray squirrel) Pathway ncar04022   cGMP-PKG signaling pathway ncar04068   FoxO signaling pathway ncar04081   Hormone signaling ncar04140   Autophagy - animal ncar04150   mTOR signaling pathway ncar04151   PI3K-Akt signaling pathway ncar04152   AMPK signaling pathway ncar04211   Longevity regulating pathway ncar04213   Longevity regulating pathway - multiple species ncar04722   Neurotrophin signaling pathway ncar04910   Insulin signaling pathway ncar04920   Adipocytokine signaling pathway ncar04923   Regulation of lipolysis in adipocytes ncar04930   Type II diabetes mellitus ncar04931   Insulin resistance ncar04932   Non-alcoholic fatty liver disease ncar04935   Growth hormone synthesis, secretion and action ncar04960   Aldosterone-regulated sodium reabsorption ncar05010   Alzheimer disease ncar05206   MicroRNAs in cancer ncar05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:ncar00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     124979751    04022 cGMP-PKG signaling pathway     124979751    04151 PI3K-Akt signaling pathway     124979751    04152 AMPK signaling pathway     124979751    04150 mTOR signaling pathway     124979751   09133 Signaling molecules and interaction    04081 Hormone signaling     124979751  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     124979751  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     124979751    04923 Regulation of lipolysis in adipocytes     124979751    04920 Adipocytokine signaling pathway     124979751    04935 Growth hormone synthesis, secretion and action     124979751   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     124979751   09156 Nervous system    04722 Neurotrophin signaling pathway     124979751   09149 Aging    04211 Longevity regulating pathway     124979751    04213 Longevity regulating pathway - multiple species     124979751  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     124979751   09164 Neurodegenerative disease    05010 Alzheimer disease     124979751   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     124979751   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     124979751    04932 Non-alcoholic fatty liver disease     124979751    04931 Insulin resistance     124979751 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  124979751 NCBI-ProteinID:  XP_047400354 LinkDB All DBs Position 3:complement(171400781..171457999) Genome browser AA seq 1242 aa AA seqDB search MASPPDTDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HEGASGPGAGGGGGSCSGSSGLGEAGEDLSYGDAPPGPAFKEVWQVILKPKGLGQTKNLI GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT RRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLTAPN GHYILSRGGNGHRYIPGAALGTSPALTADEASSAADLDNRFRKRTHSAGTSPTISHQKTP SQSSVASIEEYTEMMPAYPPGGGSGGRLPGYRHSAFVPTHSYPEEGLEMHALEHRSSHHR PDSATLHTDDGYMPMSPGVAPVPSSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN GYMMMSPSGSCSPDIGGGSSSSSSISAAPSGSSYGKLWTNGVGGHHSHALSHPKPPVESG GGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPE EGARHQHLRLSSSSGRLLYAATAEDSSSSTSSDSLGGGYCGARPDPGLPHPHHHVLQPHL PRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQPLLHPPEPKSPGEYVNIEFG SDQPGYLSGPMTSHSSPSVRCPSQLQPAPREEETGTEEYMNMDLGPGRRATWQESSGGET GRVGPAPPGSTSICRPTRAVPSSRGDYMTMQMGCPRQSYVDTSPVAPVSYADMRTGIATE EVKLPRATAAAPSSASAASSSPAAPQGTTELPAHSSLLGGPQGPGGMSAFTRVNLSPNRN QSAKVIRADPQGCRRRHSSETFSSTPTATRGANTVSFGAGAAVGGSGGGGGGNSSEDVKR HSSASFENVWLRPGELGGAPKEMAQVCGAAGGLENGLNYIDLDLVKDFKQRPQERPPQPQ PPPPPPPHQPLGSSESSSASRSSEDLSTYASISFQKQPEERQ NT seq 3729 nt NT seq  +upstreamnt  +downstreamnt atggcgagtcctccagataccgatggcttctcggacgtgcgcaaggtgggctacctgcgc aagcccaagagcatgcacaagcgcttcttcgtgttgcgggcggccagcgaggccgggggc cccgcgcgcttggagtactacgagaacgagaagaagtggaggcacaagtcgagcgccccc aaacgctccatccccctcgagagctgcttcaacatcaacaagcgtgctgactccaagaac aagcacctggtggctctctacacccgggacgagcactttgccattgcggcggacagcgag gccgagcaagacagctggtaccaggctctcctgcagctgcacaaccgtgccaaaggccac cacgaaggggcctcaggcccgggagcaggaggtggtgggggcagctgcagcggcagctcg ggcctcggggaggcaggggaggacttgagctacggagatgcgcccccgggacctgcgttt aaggaggtctggcaggtgatcttgaaacccaagggcctgggtcagacaaagaacctgatt ggcatctaccgcctctgcctgaccagcaagactattagcttcgtgaagctgaactccgag gcagcagccgtggtgctgcagctaatgaacatcagacgctgcggccactctgaaaacttc ttcttcatcgaggtgggccgttctgctgtgacagggcccggggagttctggatgcaggtg gatgactcggtggtggcacagaacatgcacgagactatcctagaggccatgcgggctatg agtgatgagtttcgccctcgaagcaagagccagtcctcatccaactgctccaatcccatc agtgtccccctgcgcaggcaccatctcaacaaccccccgcccagccaggtggggttgact cgacgatcacgcactgagagcatcactgccacctccccagccagtatggttggtgggaaa ccaggctccttccgtgtgcgcgcctccagcgatggtgaaggcaccatgtcccgcccagcc tctgtggatggcagccctgtgagccctagcaccaacaggacccacgcccaccggcatcgg ggcagctcccggctgcacccgcctctcaaccacagtcgctccatccctatgccttcttct cgctgctcgccttcggccaccagcccagttagtctgtcgtccagcagcaccagtggtcat ggctccacctcggactgtctcttcccaaggcggtctagtgcttccgtatctggttccccc agcgatggcggtttcatctcttcggatgagtatggctccagcccctgcgacttccgaagt tccttccgcagtgtcactccggattccttgggccacaccccaccagcccgaggcgaggaa gagctgagcaattatatatgcatgggtggaaagggggcctccaccctaacagctcccaat ggtcattacattttgtcccggggtggcaatggccaccgatacatcccaggagctgccttg ggcaccagcccagctttgactgcggatgaagcaagcagtgctgcagatctggataatagg ttccggaagagaacccactcggcagggacatcccctaccatttcccaccagaagacccca tcccagtcctcagtggcttccattgaggaatatacagagatgatgcctgcctatccgcca ggaggtggcagtggaggccggctgcctggctaccggcactccgccttcgtgcccacccac tcctaccctgaggagggtctggagatgcatgccttggagcaccgcagcagccaccaccgc ccagatagtgccaccctccacaccgatgatgggtacatgcccatgtccccaggggtagcc ccagtgcccagtagccggaagggcagtggggattatatgcccatgagccccaagagtgtg tctgccccgcagcagatcatcaaccccatcagacgtcatccccagagagtggaccccaat ggctacatgatgatgtcccccagtggcagctgctcccctgacattggaggcgggtccagc agcagcagcagcatcagtgctgccccttctgggagtagctatgggaagttatggacaaat ggggttgggggccaccactctcacgctctgtcccaccccaagccccctgtggagagtggt ggtggcaagctcttgccttgcacaggtgactacatgaacatgtcaccagtgggggactcc aacaccagcagcccctctgactgctactatggccccgaggacccccagcacaagccagtc ctttcttactactcgttgccaaggtcttttaagcacacccagcgccctggagagccggag gagggtgcccggcaccagcatctccgcctctcctctagctctggtcgccttctctacgct gcaactgcagaagattcttcttcctccaccagcagcgacagcctgggtgggggttactgt ggggccaggccagatcctggcctcccacatccccaccatcatgtcttgcagccccatttg cctcgaaaagtggacacagctgctcagaccaacagccgcctggctcggcccacaaggcta tctttgggggatccgaaggccagcactttgccccgggcccgagaacagcaacaacagcag cccctgctgcaccctccagagcccaaaagcccaggggaatatgtgaatattgaatttggg agtgaccagcctggctatttatctggccccatgacttcccacagctcgccttctgtccgg tgtccatcccagctccagccagctcccagagaggaagagactggcactgaggagtacatg aacatggacctggggccaggccggagggcaacctggcaggagagcagtgggggggagacg ggcagagtgggccctgcacctccagggtctactagcatttgcaggcctacccgggcagtg cccagcagccggggtgactacatgaccatgcagatgggttgtccccgtcagagctatgtg gacacctcaccagttgcccctgtcagctatgctgacatgcggacaggcattgccaccgag gaggtgaaactgcccagggccacagcggctgctccttcttcagcctcagcagcctcttct tcccctgctgcacctcaaggaacaactgagcttcctgcccactcttcccttttggggggc ccccagggtcctgggggcatgagcgccttcacccgggtaaacctcagtcccaaccgcaac cagagtgccaaagtgatccgcgcagatccacaagggtgccggaggaggcatagctccgag accttctcctcaacgcctactgctacccggggggccaacacagtgtcctttggagctggg gctgcagtagggggcagtggtggtggtggtggcggcaacagcagtgaggatgtgaagcgc cacagctctgcttcctttgagaatgtctggctgagacctggggagctaggcggagccccc aaggagatggcccaagtgtgtggagccgctgggggtttggagaatggtctcaactacata gacctggatttggtcaaggacttcaaacagcgccctcaggagcgcccccctcagccgcag cctcctccacccccacccccgcatcagcccctgggcagcagtgagagcagctctgccagc cgctccagcgaggatttaagcacctatgccagcatcagtttccagaagcagccagaagaa cgccagtag

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