Sciurus carolinensis (gray squirrel): 124980441 Help Entry 124980441         CDS       T08117                                  Name (RefSeq) caspase-8-like isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism ncar  Sciurus carolinensis (gray squirrel) Pathway ncar01524   Platinum drug resistance ncar04115   p53 signaling pathway ncar04210   Apoptosis ncar04215   Apoptosis - multiple species ncar04217   Necroptosis ncar04620   Toll-like receptor signaling pathway ncar04621   NOD-like receptor signaling pathway ncar04622   RIG-I-like receptor signaling pathway ncar04623   Cytosolic DNA-sensing pathway ncar04625   C-type lectin receptor signaling pathway ncar04657   IL-17 signaling pathway ncar04668   TNF signaling pathway ncar04932   Non-alcoholic fatty liver disease ncar04936   Alcoholic liver disease ncar05010   Alzheimer disease ncar05016   Huntington disease ncar05022   Pathways of neurodegeneration - multiple diseases ncar05132   Salmonella infection ncar05134   Legionellosis ncar05142   Chagas disease ncar05145   Toxoplasmosis ncar05152   Tuberculosis ncar05160   Hepatitis C ncar05161   Hepatitis B ncar05162   Measles ncar05163   Human cytomegalovirus infection ncar05164   Influenza A ncar05165   Human papillomavirus infection ncar05167   Kaposi sarcoma-associated herpesvirus infection ncar05168   Herpes simplex virus 1 infection ncar05169   Epstein-Barr virus infection ncar05170   Human immunodeficiency virus 1 infection ncar05200   Pathways in cancer ncar05203   Viral carcinogenesis ncar05416   Viral myocarditis ncar05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ncar00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     124980441  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     124980441    04215 Apoptosis - multiple species     124980441    04217 Necroptosis     124980441    04115 p53 signaling pathway     124980441  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     124980441    04621 NOD-like receptor signaling pathway     124980441    04622 RIG-I-like receptor signaling pathway     124980441    04623 Cytosolic DNA-sensing pathway     124980441    04625 C-type lectin receptor signaling pathway     124980441    04657 IL-17 signaling pathway     124980441  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     124980441    05203 Viral carcinogenesis     124980441   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     124980441    05161 Hepatitis B     124980441    05160 Hepatitis C     124980441    05164 Influenza A     124980441    05162 Measles     124980441    05168 Herpes simplex virus 1 infection     124980441    05163 Human cytomegalovirus infection     124980441    05167 Kaposi sarcoma-associated herpesvirus infection     124980441    05169 Epstein-Barr virus infection     124980441    05165 Human papillomavirus infection     124980441   09171 Infectious disease: bacterial    05132 Salmonella infection     124980441    05134 Legionellosis     124980441    05152 Tuberculosis     124980441   09174 Infectious disease: parasitic    05145 Toxoplasmosis     124980441    05142 Chagas disease     124980441   09164 Neurodegenerative disease    05010 Alzheimer disease     124980441    05016 Huntington disease     124980441    05022 Pathways of neurodegeneration - multiple diseases     124980441   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     124980441    05416 Viral myocarditis     124980441   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     124980441    04932 Non-alcoholic fatty liver disease     124980441   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     124980441  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ncar01002]     124980441 Enzymes [BR:ncar01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      124980441 Peptidases and inhibitors [BR:ncar01002]  Cysteine peptidases   Family C14: caspase family    124980441 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  124980441 NCBI-ProteinID:  XP_047401950 LinkDB All DBs Position 3:148538757..148578613 Genome browser AA seq 530 aa AA seqDB search MVPGKVGAGLHSPLAVILGAQIVRQETCEEGAAVVRNPGFASGYCSYLLTSMDFSKCLYN IGEQLGSDELASLKFLSLDYIPQKKQEPIKDALTLFQTLQEKGMLEESNLSFLKELLFRI NRLDLLTTYLDTSKEEMAQEVQTPGRAQISAYRVMLFQISEEVSKLELKSFKFLLSKDIP KCKLDDDLSLLDIFIEMEKKLILGERNLDMLKNICDQINKSLLKKIKDYEELSKERRMSL ERSPDAFSNGEESFRMLALSDSPGEQDSDSQTSDKVYQMKSKPRGYCLIFNNYDFSTARK DMPKLHNIKDRKGTDLDAEALSKTFTKLHFEVVPHKDSTAKEICEVLKSYQSMDHNNKDC FICCILSHGDEGIVYGTDGQKVSIYDLTSYFTGSKCPSLAGKPKVFFIQACQGDNYQKGV PVETDSEQKEAYLEMDLSFQKSYIPDEADFLLGMATVNNCVSYRNPQEGTWYIQSLCQRL RERCPRGDDILTILTEVNYEVSNKDDRKNMGKQMPQPTFTLRKKLFFPLD NT seq 1593 nt NT seq  +upstreamnt  +downstreamnt atggtcccgggaaaggttggagcaggtcttcattcgcctttggctgtcatcttaggtgca cagatagtccgacaagagacctgcgaggaaggcgctgctgttgtgaggaacccaggattt gcatctggttactgctcctacctcttgacaagcatggatttcagcaaatgtctttacaat attggggaacaactgggcagtgatgagctggcctccctcaagttcctgagcctggactac atcccacaaaagaagcaggagcctatcaaggatgccttgacgctattccagacacttcag gaaaagggaatgttggaggaaagcaatctgtccttcttgaaggagctgcttttccgaatt aatagactggacctgctgaccacttacctggacaccagcaaggaggaaatggcacaggaa gttcagactcctggcagggctcagatttctgcctacagggtcatgctttttcagatttca gaagaagtaagcaagctggaattgaaatcttttaagtttcttttgagcaaggatatcccc aagtgtaagctggatgatgacctgagcttgcttgacattttcatagagatggagaagaaa cttatcctaggggagagaaacttggatatgctgaaaaacatctgtgatcaaatcaataag agcctgctgaagaaaatcaaggattatgaagaattaagcaaagagagaagaatgagtctt gaaagaagcccagatgcattctcaaatggggaggagtccttcaggatgctggcattgtca gactctccaggagaacaagacagtgactcacagacatcagacaaagtctaccaaatgaaa agcaaacctcggggatactgtttgatcttcaacaactatgattttagcacagcacggaag gatatgcccaagcttcacaacattaaggataggaaaggaacagatttggatgcagaggct ttgagcaagacctttacgaagcttcattttgaagtagtacctcacaaagattccacagca aaggaaatctgtgaagttctgaagtcctaccaaagcatggaccacaataataaagactgc ttcatctgctgtatcctctcccatggagatgagggcatagtctatggcactgatggacag aaggtctccatctatgatctgacctcttatttcactggttcaaagtgcccttcccttgct gggaaacctaaagtcttttttattcaggcttgtcaaggggataactaccagaaaggcgta cctgttgaaactgactcagagcaaaaggaagcctacttagagatggacttatcatttcaa aagagttatatcccagatgaagctgactttctgttggggatggccactgtgaacaactgt gtttcctatcgaaacccccaggagggaacctggtatatacaatcactttgccagaggctg agagaaaggtgtccccgaggcgatgatattctcaccatcctgactgaagtgaactatgaa gtgagcaataaggatgacaggaagaacatggggaagcagatgccccagcccacatttaca ttaaggaaaaaactcttctttcctcttgattga

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