Sciurus carolinensis (gray squirrel): 124983061
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Entry
124983061 CDS
T08117
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
ncar
Sciurus carolinensis (gray squirrel)
Pathway
ncar01521
EGFR tyrosine kinase inhibitor resistance
ncar04010
MAPK signaling pathway
ncar04012
ErbB signaling pathway
ncar04020
Calcium signaling pathway
ncar04151
PI3K-Akt signaling pathway
ncar05205
Proteoglycans in cancer
ncar05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ncar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
124983061
04012 ErbB signaling pathway
124983061
04020 Calcium signaling pathway
124983061
04151 PI3K-Akt signaling pathway
124983061
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
124983061
05205 Proteoglycans in cancer
124983061
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
124983061
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ncar01001
]
124983061
Enzymes [BR:
ncar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
124983061
Protein kinases [BR:
ncar01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
124983061
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
Kinase-like
TM_ErbB1
Motif
Other DBs
NCBI-GeneID:
124983061
NCBI-ProteinID:
XP_047405919
EnsemblRapid:
ENSSCRG00010001915
LinkDB
All DBs
Position
4:116447183..116466787
Genome browser
AA seq
1338 aa
AA seq
DB search
MKANRVLQVLGFFLSLARGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLHKLYERCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFIM
LNYNTNSSHALRQLRFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNG
RSCLPCHEVCKGRCWGPGPEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQD
TDCFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTS
CVRACPPDKMEVDKNGLKICEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNLNVTSLGLRSLKEISAGRIYISANRQLCYHHSLNWTRLLRGPAEE
RLDIKHNRPRRDCVAEGKVCDSLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEP
REFAQEAECFSCHPECQPMEGSATCNGSGSDACAQCAHFRDGPHCVSSCPHGVLGAKGPI
YKYPDVQNECRPCHENCTQGCKGPELKDCLGQTLVLISKTHLAMALTVGLAVVFLILGGT
FLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVFARIFKETELRKLKVLGSGVFGT
VHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPGSS
LQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLL
KSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVW
ELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELA
NEFTRMARDPPRYLVIKRESGPGIPPGAEPPALSNKELEEVELEPELDLDLDLEAEEDSL
ATTLGSALSLPVGTLTRPRGSQNLLSPSSGYMPMNQGNLGEACQDSAACGGNEWCPRPVS
LHPVPRGRLASESSEGHVTGSEVEFSEKVSMCRSRSRSRSRSPRPRGDSAYHSQRHSLLT
PVTPLSPPGVEEEDVNGYVMPDTHLKGTSSSREGTLSSVGLSSVLGTEEDDEDEEYEYMN
RRRRHSPPCAPRPGSLEELGYEYMDVGSDLSASLGSTQSCPLHPMPTAGTTPDEDYEYMN
RRRGGSGPGGEYASMGACPASEQGYEEMRAFQGPGHQTPHVRYARLKTLRSLEATDSAFD
NPDYWHSRLFPKANAQRT
NT seq
4017 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcaaaccgggttctgcaggtgctgggcttctttcttagcctagcccggggctcc
gaggtgggcaactcgcaggcagtgtgtcccgggaccctgaatgggctgagtgtgactggt
gatgcggagaaccaataccagacactacacaagctctacgagcgatgtgaggtggtgatg
gggaaccttgagattgtgctcacaggacacaatgctgacctcagcttcttacagtggatc
cgagaagtgacaggctatgtccttgtggccatgaatgaattttctacactaccattgccc
aacctccgagtggtgagaggtacccaggtctatgatgggaagtttgccatcttcatcatg
ttgaactataacaccaactctagccatgctctgcgccagctccgcttcactcagctcacc
gagattctgtcagggggcgtttatattgagaagaatgataaactttgccacatggacaca
attgactggagggacatcgtgagggaccgagatgctgagatagtggtgaaggacaatggc
agaagctgtctcccttgtcatgaggtctgcaaagggcgatgttggggtcctggaccagaa
gactgccagacattaaccaagaccatctgtgcccctcaatgtaatggtcattgctttggg
cccaaccccaaccagtgctgccatgacgagtgtgcagggggctgctcaggccctcaggac
actgactgctttgcctgccgacacttcaatgacagtggagcctgtgtgccccggtgccca
cagcctcttgtgtacaacaagctaactttccagctggaacctaatcctcacaccaagtac
cagtatggaggagtttgtgtagccagttgtccccataactttgtggtagaccagacgtcc
tgtgtcagggcatgtcctcctgacaagatggaagtagataaaaatggactcaagatatgt
gagccttgtggtgggctatgccctaaagcctgtgaggggacgggctctgggagccgcttc
cagactgtggactcaagcaacatcgatgggtttgtgaattgcaccaagattctgggcaac
ctggactttcttatcaccggcctcaatggagacccctggcacaagatccctgccctggac
cctgagaagctcaatgtcttccgaacagtacgggagatcacaggttacctgaacatccag
tcctggcctcctcacatgcataacttcagtgttttttccaacctgacaaccattggaggc
agaagcctttacaaccggggcttctcattgttaattatgaagaacttgaatgtcacatcg
ctgggcctgcgatccctgaaggaaattagtgctgggcgtatctacataagtgccaatcgg
cagctctgctaccaccactctctgaactggaccaggctgcttcgggggcctgcagaagag
agactagacatcaagcataatcggccacgcagagactgtgtggcagagggcaaagtgtgt
gactcactgtgctcctccggaggatgctggggcccaggccctggtcagtgcttatcctgt
cgaaactacagtcgagggggtgtctgtgtgacccactgcaactttctaaatggggagcct
cgtgagtttgcccaggaggctgaatgcttctcctgccacccagaatgccaacccatggag
ggcagtgccacatgcaatggctcgggctctgatgcttgtgcccagtgtgcccattttcga
gatgggccccactgtgtgagcagctgccctcatggagtcctaggtgctaaggggcccatc
tacaagtacccggatgttcagaatgaatgtcggccctgccatgagaactgcacccagggg
tgtaagggaccagagctaaaagactgtttaggccaaacactggtgctgatcagcaaaacc
catctggcaatggctttgacagtaggattggcagtggttttcctgattctgggaggcact
tttctctattggcgtgggcgccggattcagaataaaagggctatgaggcgctacttggaa
cggggtgagagtatagaacctctggatcccagtgagaaagctaacaaagtcttcgccaga
atcttcaaagagacagagctgaggaagcttaaagtgcttggttcaggcgtctttggaaca
gtgcataaaggagtatggatccccgaaggtgaatcaatcaagattccagtttgcattaaa
gtcattgaggacaagagtggacggcaaagtttccaagctgtaacagatcatatgctggcc
attggcagcctagaccatgcgcacattgtacggttgctcggactatgcccagggtcatct
ctgcaacttgtcactcagtacttgcctctgggttccctactggatcatgtgagacaacac
cggggggcactggggccacagctgctcctcaactggggagtacaaattgccaagggtatg
tactatcttgaagagcatggtatggtgcacaggaacctggctgcccgaaatgtgttactc
aagtcacccagtcaggttcaagtggcagattttggtgtggctgacctgctgccacctgat
gataagcagctattacacagtgaggccaagactccaattaagtggatggcccttgagagt
atccactttgggaaatacacacaccagagtgacgtctggagctatggtgtgacagtttgg
gagttgatgacctttggagcagagccctatgcaggactccgattagctgaagtaccagac
ctgctagagaagggggagcggttagcacagccccagatctgcaccattgatgtctacatg
gttatggtcaagtgttggatgattgatgagaatattcgcccaacctttaaagaactagcc
aatgagtttaccaggatggcccgtgatccaccaaggtatctggtcataaagagagagagt
gggcctggaataccacctggggcagaaccccctgctctgtcaaacaaggaactggaagaa
gtagagctggaaccagaacttgacctagacctagacttggaggcagaggaggacagcctg
gcaaccacattgggctctgccctcagcctaccagttggaacacttactcggccacgtggg
agccagaaccttttaagtccatcatctggatacatgcccatgaaccagggtaaccttgga
gaggcttgccaggattctgcagcttgtgggggtaatgaatggtgtccccgtccagtctct
ctgcacccagtgccacggggacgcctggcatcagagtcgtcagagggccatgtgacagga
tccgaggttgagttctcagagaaggtgtcaatgtgtagaagccggagccggagccggagc
cggagcccacggccacgtggagatagtgcctaccattcccagcgccacagcctgcttact
cctgtcaccccactctccccaccgggggtagaggaagaggatgtcaatggttatgtcatg
ccagatacacacctcaaaggtacttcttcctcccgggaaggcaccctttcttcagtgggt
ctcagttctgtcttgggtactgaagaagacgatgaagatgaggagtatgaatacatgaac
cggaggagaaggcacagtccaccttgtgcccctaggcctggttcccttgaggaactgggt
tatgagtacatggatgtaggatcagacctcagtgcctcactgggcagcacacagagttgc
ccactccaccctatgcccactgctggcacaactccagatgaggactatgaatatatgaat
cggcggcgtggtggaagtggtccaggtggggaatatgcatccatgggggcctgtccagca
tctgaacaagggtatgaagaaatgagagctttccagggacctggacaccaaaccccccat
gtccgttatgcccgcctcaaaactctacgtagcttagaagccactgactctgcctttgat
aaccctgattactggcatagcaggcttttccctaaggctaatgcccagagaacataa
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