Sciurus carolinensis (gray squirrel): 124984569 Help Entry 124984569         CDS       T08117                                  Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism ncar  Sciurus carolinensis (gray squirrel) Pathway ncar04022   cGMP-PKG signaling pathway ncar04068   FoxO signaling pathway ncar04081   Hormone signaling ncar04140   Autophagy - animal ncar04152   AMPK signaling pathway ncar04211   Longevity regulating pathway ncar04213   Longevity regulating pathway - multiple species ncar04910   Insulin signaling pathway ncar04920   Adipocytokine signaling pathway ncar04923   Regulation of lipolysis in adipocytes ncar04930   Type II diabetes mellitus ncar04931   Insulin resistance ncar04932   Non-alcoholic fatty liver disease ncar04935   Growth hormone synthesis, secretion and action ncar05010   Alzheimer disease ncar05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:ncar00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     124984569    04022 cGMP-PKG signaling pathway     124984569    04152 AMPK signaling pathway     124984569   09133 Signaling molecules and interaction    04081 Hormone signaling     124984569  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     124984569  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     124984569    04923 Regulation of lipolysis in adipocytes     124984569    04920 Adipocytokine signaling pathway     124984569    04935 Growth hormone synthesis, secretion and action     124984569   09149 Aging    04211 Longevity regulating pathway     124984569    04213 Longevity regulating pathway - multiple species     124984569  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     124984569   09164 Neurodegenerative disease    05010 Alzheimer disease     124984569   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     124984569    04932 Non-alcoholic fatty liver disease     124984569    04931 Insulin resistance     124984569 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  124984569 NCBI-ProteinID:  XP_047408311 LinkDB All DBs Position 5:3150375..3175546 Genome browser AA seq 1344 aa AA seqDB search MASPPLHGSPGQAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAAGDEA TATAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTK DEYFAVAAENEQEQEGWYRALTDLVSEGRASAGDPAPAASAPAASCSASLPGALGGSAGA AAADDSYGLVAPASTAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPS VTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKEL FEFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPATKCS SCRVRTASEGDGGVAAGTVAAAGRPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVT LAPAGGALQHSRSMSMPVSHSPPAATSPGSLSSSSGHGSGSYPLPPGPHPHLPHPLHHPP GQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGGE LYGYMTMDRPLSHCGRPYRRVSGDGVQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEY TLMRATFSGSSGRLCPSFPTSSPKMTYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTP GAALMGSGSGSCKSEDYMPMSPTSVSAPKQILQPRVSPAADLPPTGAAAPQPASVASRTF PVSGSSYKASSPAESSPEDRGYMRMWCGSKLSVESADPKLLPNGDYLNMSPSDAGTAGTP PDFFSAALHGSGEVLKGVPGYCYSSLPRSYKAPYASSGDSDQYVLMSSPVGRILEEERLE PQATPVTSPSASTFGSGGGGHTQPHHPAVPSPVRPSSGGRPEGFLSQRCRAVRPTRLSLE GLQTLPSMHEYPLPPEPKSPGEYINIDFGEAGARLSPPAPPLLASAASSSSLLSASSPAS SLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGVRSADPVGSLDALLSPEAASPYPP LPPRPPASPTSLQQQPSSQPPPGEPYRLPPASGAATTQGPSAASSTSSETGDNGDYTEMA FGVAATPPQPIVAHPKPEGARVTSPTSGLKRLSLMDQVSGVEAFLQASQPPDPHRGAKVI RADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHSSASVENVSLRKSGEGSGGGTLGG GLGASEEPPTSPGQLQPSLPVPPPPQVRPWAPGQPGGLVGCPGGSGSPMRRETSAGFQNG LNYIAIDVRDEPGLSPQVQMQHPQPGDKSWGRTRSLGGLLSTVGGSGTSGVCGGPGPGAL PSANTYASIDFLSHHLKEATIVKE NT seq 4035 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgctgcatggatcccccgggcaggcgggcggcgacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgtttcttcgtgctgcgcgggcctggcgcggctggcgacgaggcg acagcgactgcgggcggggggtcggcgccgcagccgccgcggctcgagtactacgagagc gagaagaagtggcggagcaaggcgggcgccccgaagcgggtgatcgcgctcgactgctgc ctgaacatcaacaagcgcgcggacgccaagcataagtacctgatcgccctctacaccaag gacgagtatttcgccgtggcggcggagaacgagcaggagcaggaaggctggtaccgcgcg ctcacggacctggtcagcgagggccgcgcgagcgccggcgacccggcccccgccgcctcg gcccccgccgcgtcctgcagcgcctccctccccggcgccctgggcggctcggccggcgcc gccgcggccgatgacagctacgggctcgtggcgcccgcctcgaccgcctaccgcgaggtg tggcaggtgaacctgaagcccaagggcctgggccagagcaagaacctgacgggcgtgtac cgcctgtgcctgtcggcgcgcaccatcggcttcgtgaagctcaattgcgagcagccgtcg gtgacgctgcagctcatgaacattcgccgctgcggccattcggacagcttcttcttcatc gaggtgggccgttcggccgtcacgggccctggagagctgtggatgcaggccgacgactcg gtggtggcgcagaatatccacgagaccattctggaggccatgaaggcgctcaaggagctc ttcgagttccggccgcgcagcaaaagccagtcgtcgggatcgtccgccacgcatcccatc agcgtccctggtgcgcgccgccaccaccacttggtcaacttgccccctagtcagacaggc ctggtgcgccgctcgcgcacagatagcctggccgccacccccccggccaccaagtgtagt tcgtgccgggttcgcacagccagtgagggcgacgggggcgttgcggccgggactgtggcg gcggccggcaggccggtgtcggtagctggaagccccctgagccctgggccggtgcgcgcg cccctgagccgctcgcacaccctgagtggcggctgcggtggccgcggaagcaaagtgacg ctggcgccggcagggggcgccctgcaacacagccgctccatgtccatgccagtgtcacac tcgcccccggctgccaccagccccggcagcctgtcgtccagcagcgggcacggctcaggc tcctacccgctgccgccgggcccgcacccccacctgcctcaccccttgcatcaccctcca ggtcagcggccctccagcggcagcgcctccgcctcaggctcccccagtgaccctggcttc atgtccctggacgaatacggctctagccctggtgacctgagagccttctgcagccacagg agcaacacacccgagtccatcgctgagacacccccagccagggatggcagcgggggtgag ttgtatgggtacatgaccatggacaggcctctgagccactgtggccgcccctatcgcaga gtctcaggggatggggtccaggacttggacagaggactaagaaagaggacttactccttg accacgcctgctaggcagcggccagtgccccagccctcctctgcctccctggatgagtac actctgatgcgggccaccttctctggaagctcaggccgcctctgcccttctttccccact tcctctcccaaaatgacctaccacccctatccagaggactatggggacatagagattgga tcccacaggagttccagcagcaatctgggggctgatgatggctacatgcccatgacccct ggtgcagcccttatgggcagtggcagcggcagctgcaagagcgaggactacatgcccatg agccccaccagcgtgtccgccccaaagcagatcctgcagccacgagtgtcacctgcagca gacctgccccccacgggagcggcagcaccacagcccgcctctgtggccagcaggaccttc ccagtgagcgggagcagctacaaggccagctcccccgcggaaagctcgcccgaggacagg gggtacatgcgcatgtggtgtggctccaagctgtcagtggagtctgccgacccaaagctg cttcccaatggggactacctcaacatgtcccccagcgacgcaggcaccgcgggcacaccg cccgatttcttctcagcggccctgcacggcagtggggaggtgctcaaaggcgtccctggc tactgctacagttccttgccccgctcctacaaggccccttatgcctccagtggggacagt gaccagtacgtgctcatgagctcccccgtgggacggatcctggaagaggagaggctggaa ccccaggccaccccagtgacctccccttcggccagcacctttgggtctggcgggggtggc cacacccagcctcatcacccagcagtgccttcacctgtgaggcccagcagtggtggccgc ccagagggtttcctgagccagcgctgccgggcggtgcggcccacacgcctgtccctggag gggctgcaaaccctgcccagcatgcatgagtaccccctgccaccagagcccaagagccct ggagaatacatcaacattgactttggcgaagcgggtgcccgcctctcaccacctgcgcct ccactgctggcatcggccgcctcatcctcctcgctgctgtccgccagtagcccggcttcg tccctgggctcgggcaccccgggcacgagcagtgacagccggcagcgctccccgctgtcc gattacatgaacctggacttcagttctcccaagtcccccaagccgggcgtccgaagtgcg gaccctgtgggctccctggatgccctcctctcccccgaggctgcttctccatacccaccc ctgcctccgcgtcctcctgcctctccgacctccctgcagcaacagccctcttcacagcct cctccaggggaaccgtaccgtctgcctccagcatcgggcgctgccaccacccagggcccc agtgctgcctcttccacatcctccgagactggggacaatggtgactacaccgagatggcc tttggtgtggctgccaccccgcctcaacccattgtggcccaccccaaaccggaaggtgcc cgagtgaccagccccacatcgggcttgaagaggctgagtctcatggatcaggtgtcaggg gtcgaagccttcctgcaggccagccagcccccagacccccatcggggggccaaggtcatc cgtgcagacccacaggggggccgccgccgccacagctcggagaccttctcctcgaccacc acagtcaccccggtgtccccatccttcgcccataaccccaagcgccacagctcggcctct gtagaaaatgtctctctcaggaaaagcggcgagggtagtggagggggcaccctgggtggg ggtcttggagccagcgaggagccacccacatccccgggtcagttgcagccatcgcttcct gtgcctccaccgccacaggtgcggccttgggcccccggccagcctgggggcttggtgggc tgtcctgggggcagtggttcgcctatgcgaagagagacctctgcgggtttccagaatggc ctcaactacatcgccatcgacgtgagggacgagccagggctgtccccccaggtgcagatg cagcatccgcagccaggagacaagagctggggccggacccgtagccttgggggtctcctc agcactgtggggggcagcggcaccagcggggtgtgtggtggtccgggccctggtgccctg ccctcggccaacacctacgccagcattgacttcttgtcccatcacttgaaagaggccacc atcgtgaaagagtga

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