Sciurus carolinensis (gray squirrel): 124985472
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Entry
124985472 CDS
T08117
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret isoform X1
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
ncar
Sciurus carolinensis (gray squirrel)
Pathway
ncar04010
MAPK signaling pathway
ncar04020
Calcium signaling pathway
ncar04151
PI3K-Akt signaling pathway
ncar05200
Pathways in cancer
ncar05216
Thyroid cancer
ncar05223
Non-small cell lung cancer
ncar05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ncar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
124985472
04020 Calcium signaling pathway
124985472
04151 PI3K-Akt signaling pathway
124985472
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
124985472
05230 Central carbon metabolism in cancer
124985472
09162 Cancer: specific types
05216 Thyroid cancer
124985472
05223 Non-small cell lung cancer
124985472
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ncar01001
]
124985472
Enzymes [BR:
ncar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
124985472
Protein kinases [BR:
ncar01001
]
Receptor tyrosine kinases (RTK)
RET family
124985472
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD3
RET_CLD1
Pkinase
RET_CRD
Cadherin
Cadherin_FAT4_N
RIO1
Pkinase_fungal
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
124985472
NCBI-ProteinID:
XP_047410165
LinkDB
All DBs
Position
5:90627420..90681241
Genome browser
AA seq
1134 aa
AA seq
DB search
MDKATSGAAGLRLLLLLPLLGEAPLGLYFSRDAYWERLYVDQPAGTPLLYVHALRDTPGE
VPSFRLGQHLYSAHRTRLHENNWIRVQEDTGLLYLNQSLDHTFWEKLSIRSKRAHPTSPL
LHSQATLTRAPVDGGFPLLTIFLQVFLSSTPLRESDCQWPGCARVYFFFINTSFPACSSL
KPRELCFPETALSFRIRENRPPGTFHQFRLLPVHFFCPNISVAYRLLEGESLPFRCDPDS
LEVSTRWALDREQQEKYDLVAQCTVRIGKREEEVMVPFPVTVYDEDDSAPTFPGGVDTAS
AVVKFKRKEGTVVATLRVFDADVVPASGELVRRYTNTLLPGDSWAQQTFRVEHSPNETLA
QANGSFVRATVHDYKLVLNRSIPISESRPLQLTVLVNDSDFQGPGTGVLLLHFNVSVLPV
ILRLPSTYSFSVNKRARHYAQIGKVCVENCQEFSGIHIQYKLQPSSTNCSVLGVVTSAED
TSGILFINDTETLQRPECAELQYTVVATDRQARKQAQAPLLLTVEGTYVAEEEGCPLSCS
GNKRRSECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPNTKTCPDGHCDALENQNINI
CPQDCLRGSIVGGHEPGERRGIKAGYGICSCFLEEKKCFCEPEDSQGPLCDELCRTVIAA
AVLFSFIVSVLLSTFCIHRYHKHAHKPPIASAEMTFCRPAQAFPVSYSSSGARRPSLDSM
ENQVSVDAFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKML
KENASPSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSR
KVGPGYMGSGGSRNSSSLDHPDERALTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNI
LVAEGRKMKISDFGLSRDVYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGIL
LWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFAD
ISKDLEKMMVKSRDYLDLAASTPSDSLLYDDGLSEEETPLVDCNNAPLSRTLPSTWIENK
LYGMSDPNWPGESPVPLTRADGTNTGFPRYANDSVYANWMVSPSAAKLMDTFDS
NT seq
3405 nt
NT seq
+upstream
nt +downstream
nt
atggataaggcgacgtccggcgccgcggggctgcggctgctgctgttgctgccgctgcta
ggcgaagcccccctgggcctctatttctcaagagatgcttactgggagaggttgtatgtg
gaccagccagctggcacacccctgctctatgtccatgccctccgggacacccctggagag
gtacccagctttcgcctgggccagcatctctatagcgcccaccgcacacgacttcatgag
aacaactggatccgtgtccaggaggacactggccttctctacctcaaccagagcctggac
cacaccttctgggagaaactcagcatccgcagtaagagagcacaccccacctcacctctg
cttcattctcaagccaccctcaccagggctcctgtggatggcggcttccccctgctcacc
atcttcctccaggtcttcctgtcatccacacccctgcgtgagagtgactgccagtggcca
ggttgtgcccgcgtgtacttcttcttcatcaacacctccttcccagcatgcagctccctc
aaacccagagaactttgcttccctgagacagccctctccttccgcatccgggaaaatagg
ccccctggcaccttccatcagttccgcctgttgcccgtgcacttcttctgcccaaacatc
agcgtggcctataggcttctggaaggtgagagtctgcccttccgctgtgacccggacagc
ctagaggtgagcacgcgctgggccctggatcgtgagcagcaggagaaatatgacctggta
gcccagtgcaccgtgcgcattggaaagcgtgaggaagaggtgatggtgcccttccctgtg
accgtgtacgacgaggacgactcggcccccaccttccccggaggcgtggacaccgccagc
gcagtggtcaaattcaagcggaaggagggcactgtggtggccaccctgcgtgtcttcgat
gcggatgtggtaccagcatctggggaacttgtaaggcgatatacaaacacgctgctccct
ggggactcctgggcccagcagaccttccgtgtggagcattcacccaacgagaccttagcc
caggccaacggcagcttcgtgcgggcaactgtgcacgactataagctggttctcaaccgg
agcatccccatctcagagagccgacccctgcagctgactgtgctggtcaatgactcagac
ttccagggtccagggacaggtgttctccttctccacttcaatgtgtcggtgctacctgtc
attctacgcctgcccagcacctattccttctctgtaaacaagagggcccgccattatgcc
cagattgggaaagtctgtgtggaaaactgccaggaattcagcggcatccacatccagtac
aagctgcagccatccagcaccaactgtagtgtcctgggggtggtcacctcagctgaggac
acctcagggatcctgttcataaatgatacggagaccctgcagcgacctgaatgtgccgag
ctccagtacaccgtggtggccactgaccggcaggcccgcaagcaggcccaggccccactg
ctcctcacagtggaggggacatacgtggctgaggaggaaggctgccccctatcctgttca
ggtaacaagaggcggtctgaatgtgaagagtgtggtggcctgggctctccaacaggcagg
tgcgagtggaggcagggagatggcaaagggatcaccaggaacttctccacctgctccccc
aacaccaagacctgccctgatggtcactgtgatgctttggagaatcagaatatcaacatc
tgcccccaggactgcctccggggcagcattgttgggggacatgagccaggggagcgccgg
ggcattaaagctggatatggcatctgcagctgcttcctggaggagaagaagtgcttctgt
gaaccggaggacagccagggcccattgtgtgatgaattgtgccgcacagtgattgcagca
gctgtcctcttctccttcatcgtctcagtcctgctctctaccttctgcatccaccgctac
cacaagcatgcccacaaaccacccattgcctctgctgagatgaccttctgtcggcccgcc
caggccttcccggtcagctactcctcatctggtgcccgccggccctcactggactccatg
gagaaccaagtctctgtggatgccttcaagatcccggaggatccaaagtgggaatttcct
cggaagaacttggttcttggaaaaaccctgggagaaggtgaatttggaaaagttgtcaag
gcaacagcattccgtctgaagggcagagcagggtacaccactgtggccgtgaaaatgctg
aaagagaatgcctctccaagtgagctgcgggacctgctatctgagttcaacctcctgaag
caggtcaaccacccacatgtcatcaagctctatggggcctgcagccaggatgggccactc
cttctcattgtggaatatgccaagtatggctccctgcggggtttcctccgagacagccgc
aaggtggggcctggctacatgggcagtggaggcagccgcaattccagctctttggaccac
ccagatgagcgggcgctgaccatgggtgacctcatctcctttgcctggcagatctcaagg
ggcatgcagtacctggctgagatgaagcttgtccatcgggacttggcagccagaaacatc
ctggttgctgaggggcggaagatgaagatttcagattttgggctgtcccgagatgtttat
gaagaagattcttatgtgaagagaagcaagggccggattcctgtcaagtggatggcaatc
gagtcccttttcgatcatatctacaccacccaaagtgatgtgtggtccttcgggattcta
ctgtgggagattgtgaccctggggggaaacccctaccctgggattcctcctgagcggctg
ttcaaccttctgaagacaggccaccggatggagaggccagacaactgcagtgaagagatg
taccgtctgatgctgcagtgctggaagcaagaaccagacaagaggccagtgtttgctgac
atcagcaaagacctggagaagatgatggtcaagagcagagactacttggaccttgctgca
tccaccccatctgactcattgctttatgatgatggcctctcagaagaggagacacccctg
gtggactgtaataatgctcccctctctcgcaccctcccttccacatggattgaaaacaaa
ctctatggcatgtcagacccgaactggcctggagagagtcctgtaccactcacgagagcc
gatggcactaacactgggtttccaagatatgcaaatgatagtgtatatgctaactggatg
gtttcaccctcagcggcaaaattaatggacacgtttgatagttaa
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