Sciurus carolinensis (gray squirrel): 124986736 Help Entry 124986736         CDS       T08117                                  Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism ncar  Sciurus carolinensis (gray squirrel) Pathway ncar04064   NF-kappa B signaling pathway ncar04380   Osteoclast differentiation ncar04650   Natural killer cell mediated cytotoxicity ncar04658   Th1 and Th2 cell differentiation ncar04659   Th17 cell differentiation ncar04660   T cell receptor signaling pathway ncar05135   Yersinia infection ncar05166   Human T-cell leukemia virus 1 infection ncar05235   PD-L1 expression and PD-1 checkpoint pathway in cancer ncar05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:ncar00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     124986736  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     124986736    04660 T cell receptor signaling pathway     124986736    04658 Th1 and Th2 cell differentiation     124986736    04659 Th17 cell differentiation     124986736   09158 Development and regeneration    04380 Osteoclast differentiation     124986736  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     124986736   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     124986736   09171 Infectious disease: bacterial    05135 Yersinia infection     124986736   09163 Immune disease    05340 Primary immunodeficiency     124986736  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ncar01001]     124986736   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:ncar03036]     124986736 Enzymes [BR:ncar01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      124986736 Protein kinases [BR:ncar01001]  Non-receptor tyrosine kinases   SRC family    124986736 Chromosome and associated proteins [BR:ncar03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     124986736 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH2_1 Haspin_kinase SH3_16 SH3_3 Motif Other DBs NCBI-GeneID:  124986736 NCBI-ProteinID:  XP_047411368 LinkDB All DBs Position 1:complement(186092302..186112759) Genome browser AA seq 509 aa AA seqDB search MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKGTLLMRNGSEVRDPLVTYEGSNPPASP LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGLEGFIPFNFVAKAN SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH YKIRNLDNGGFYISPRITFPGLHELVRHYTNTSDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHPRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMMLCWKER PEDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtagctgcagctcaaaccctgaagatgactggatggaaaatatcgatgtgtgt gagaattgccattatcccatagttccactggacggcaagggcacgttgctcatgaggaat ggctctgaagtacgggacccacttgtcacctatgagggctccaaccccccagcttcccca ctgcaagataacctggttatcgccctgcacagctatgagccctctcacgacggagacctg ggcttcgagaagggtgaacagctccgcatcctggaacagagtggcgagtggtggaaggca cagtccctgaccacaggcctggaaggcttcatccctttcaacttcgtggccaaagcgaac agcctggaaccggaaccctggttcttcaagaacctgagccgcaaggacgctgagcggcag ctcctggcgcccgggaacacgcacggttccttcctgatccgagagagcgagagcacagcg ggatcgttttcactgtcggtccgggacttcgaccagaaccagggagaggtggtgaaacat tacaagatccgtaacctagacaacggcgggttctacatctcccctcgcatcacttttccc ggactgcatgaactggtccgccattacaccaatacttctgatgggctgtgcactaggttg agccgcccctgccagacacagaagccccagaagccgtggtgggaggacgagtgggaggtt cccagggagacgctgaagctggtggagcgactgggggccggccagttcggggaggtgtgg atggggtactacaacgggcacacgaaggtggcggtgaagagcctgaagcagggcagcatg tcccctgacgccttcctggctgaggccaacctcatgaagcagctgcagcacccgcggctg gtccggctctacgcggtggtcacccaggagccaatctacatcatcactgaatatatggag aatgggagcctggtggattttctcaagactccctcaggcatcaaattgaccatcaacaaa ctcttagacatggcagcccaaattgcagagggcatggcattcatcgaagagcggaattac atccaccgtgacctgcgagctgcaaacatcctggtgtctgacactctgagttgcaagatt gcagactttggcctagcacgtctcatcgaggataatgagtacacagccagggagggggcc aaatttcccattaagtggacagcaccagaggccattaactacgggacattcaccatcaag tcagatgtgtggtcttttggaattctattgacagagattgtcacccatggccgtatccct tacccagggatgaccaatcctgaggtgattcagaatctagagcgaggctaccgcatggta aggcctgacaactgtccagaggagctgtaccaactcatgatgctgtgctggaaggagcgt ccagaggaccggcccacctttgactacctgcgcagtgtactggaggacttcttcacggcc acagagggccagtaccagccccaaccttga

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