KEGG   Sciurus carolinensis (gray squirrel): 124986783
Entry
124986783         CDS       T08117                                 
Name
(RefSeq) dihydrofolate reductase isoform X1
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ncar  Sciurus carolinensis (gray squirrel)
Pathway
ncar00670  One carbon pool by folate
ncar00790  Folate biosynthesis
ncar01100  Metabolic pathways
ncar01240  Biosynthesis of cofactors
ncar01523  Antifolate resistance
ncar04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:ncar00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    124986783
   00670 One carbon pool by folate
    124986783
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    124986783
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    124986783
Enzymes [BR:ncar01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     124986783
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 124986783
NCBI-ProteinID: XP_047411473
LinkDB
Position
6:complement(66164525..66183564)
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTPSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINIVLSRDLKELPQGAHFLANSLNDALKLTEQPELASKVDMVWIVGGSS
VYKEAMNQPGHIKLFVTRIMQEFESDTFFPEIDLEKYKLLPEYPGVLSEVQEEKGIKYKF
EVYEKND
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtccgctaaactgcatcgttgcggtgtcccagaacatgggcatcggaaagaat
ggggatctgccctggcctccgctcaggaatgaattcaagtatttccaaagaatgaccacg
accccttcagtagaaggtaaacagaatctggtgattatgggtaggaagacctggttctct
attcctgagaagaatcgacctttaaaggacagaattaatatagttctcagtagagatctc
aaggaacttccacaaggagctcattttcttgccaacagtctgaacgatgccttaaaactt
actgagcagccagaattagcaagtaaagtagacatggtttggatagtaggaggcagttct
gtttataaggaagccatgaatcaaccaggtcatattaaactgtttgtgacaagaatcatg
caggaatttgaaagtgacacattttttccagaaattgatttggagaaatataaacttctt
ccagaatacccaggtgttctttctgaggtccaggaggagaaaggcattaagtacaaattt
gaagtatatgaaaaaaatgattaa

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