KEGG   Sciurus carolinensis (gray squirrel): 124986803
Entry
124986803         CDS       T08117                                 
Name
(RefSeq) platelet-derived growth factor receptor beta isoform X1
  KO
K05089  platelet-derived growth factor receptor beta [EC:2.7.10.1]
Organism
ncar  Sciurus carolinensis (gray squirrel)
Pathway
ncar01521  EGFR tyrosine kinase inhibitor resistance
ncar04010  MAPK signaling pathway
ncar04014  Ras signaling pathway
ncar04015  Rap1 signaling pathway
ncar04020  Calcium signaling pathway
ncar04072  Phospholipase D signaling pathway
ncar04151  PI3K-Akt signaling pathway
ncar04510  Focal adhesion
ncar04540  Gap junction
ncar04630  JAK-STAT signaling pathway
ncar04810  Regulation of actin cytoskeleton
ncar05165  Human papillomavirus infection
ncar05200  Pathways in cancer
ncar05206  MicroRNAs in cancer
ncar05214  Glioma
ncar05215  Prostate cancer
ncar05218  Melanoma
ncar05230  Central carbon metabolism in cancer
ncar05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ncar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    124986803
   04014 Ras signaling pathway
    124986803
   04015 Rap1 signaling pathway
    124986803
   04630 JAK-STAT signaling pathway
    124986803
   04020 Calcium signaling pathway
    124986803
   04072 Phospholipase D signaling pathway
    124986803
   04151 PI3K-Akt signaling pathway
    124986803
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    124986803
   04540 Gap junction
    124986803
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    124986803
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    124986803
   05206 MicroRNAs in cancer
    124986803
   05230 Central carbon metabolism in cancer
    124986803
   05231 Choline metabolism in cancer
    124986803
  09162 Cancer: specific types
   05214 Glioma
    124986803
   05218 Melanoma
    124986803
   05215 Prostate cancer
    124986803
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    124986803
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    124986803
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ncar01001]
    124986803
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:ncar04090]
    124986803
Enzymes [BR:ncar01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     124986803
Protein kinases [BR:ncar01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   124986803
CD molecules [BR:ncar04090]
 Proteins
  124986803
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 ig I-set Ig_2 V-set VEGFR-1-like_Ig-like C2-set_2 VEGFR1-3_N_Ig-like Haspin_kinase TrmE_N
Other DBs
NCBI-GeneID: 124986803
NCBI-ProteinID: XP_047411513
LinkDB
Position
6:complement(108024744..108062649)
AA seq 1112 aa
MSSKDIMQLPDVTSTRVLKGQLLLLPMLLLLGPQTSQGLIIMPPGPELVLNFSSTFVLTC
LGSDPVVWERLSHVPQQKVARSQDGTFSSMLTLTNVTGADTGEYFCTYNSSLGLEPSERK
RLYIFVPDPTMGFLPMEPEDLFIFLTEITETTIPCRVTDPQLVVTLHEKKEDIPLPIPYD
HQRGFSGTFEDKTYICRTTIGEREVDSDAYYIYSLQVSSINVSVNAVQTVVRQGENITIM
CIVTGNEVVNFEWTYPRMESGRLVEPVTDFLFDVPSHIRSILHIPNAELDDSGTYICNVS
ESVNDHRDEKAINVTVVESGYIRLLEDLGPIQIAELHRSRTLQVVFEAYPPPTVLWFKDN
RTLGDSSAGEIALSTRNVSETRYVSDLTLVRVKVAEAGYYTMRAFHEDAEAKLSFKLQVN
VPVRVLELSESHPANGEQTVRCRGRGMPQPNVTWSTCRDLKRCPRELPPIPLGNSSEEES
QLETNVTYWAEEQEYEVVSTLRLRHVDQPLSVRCMLHNPLGQDMQEVTVVPHSLPFKVVV
ISAILALVVLTVISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWE
LPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQSTMKVAVKMLKSTARSSEKQALMSELKI
MSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHSFLQHHSDKRRPPSAE
LYSNALPVGPPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVTYADIESSSYMAP
YDNYVPSAPERTCRATLINESPVLSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLI
CEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLW
EIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYQIMQKCWEEKFEVRPPFSQL
VLLLERLLTEGYKKKYQQVDEEFLRSDHPAILRSQARLPGFHSLRSPLDTSSVLYTAVQP
SEGDNDYIIPLPDPKPETADEGPLEGSPSLASSTLNEVNTSSTISCDSPLDPQEEPEPES
LPKPPVEAQLELEPPMETGCPGPRIEAEDSFL
NT seq 3339 nt   +upstreamnt  +downstreamnt
atgagcagcaaggatatcatgcagcttccagatgtgacatccactcgggtcctcaaaggc
cagttgctgttgctgcccatgctgttgctgctggggccacagacctcccagggcctgatc
atcatgcccccagggccagagctcgtacttaatttctcaagcaccttcgttctgacctgc
ctgggttcagatccagtggtgtgggaacggctatctcatgtgcctcagcagaaagtggcc
aggagccaggatggcaccttctctagcatgctaaccctgaccaatgtcactggcgctgac
acaggagagtacttttgcacctacaacagttcccttggactggagcccagtgagaggaag
cggctctacatctttgtgccagatcctaccatgggcttcctcccaatggagcctgaggac
ctattcatctttctcacggaaataactgagaccacaattccatgccgagtgaccgacccc
cagctagtggtgacactgcacgagaagaaggaggacatcccactgcctatcccctatgac
caccaacgaggcttctctggtacctttgaggacaagacctacatctgcagaaccaccatt
ggggagagggaagtggattctgatgcctactacatctacagcctccaggtttcatccatc
aatgtctcggtgaatgcagtgcagactgtggttcgccagggtgagaacattaccatcatg
tgcattgtgacagggaatgaggtggtcaactttgagtggacgtacccccgcatggagagt
gggcgcctggttgagccagtgacagatttcctctttgatgtgccctcccacattcgctcc
atcctgcacatccccaatgctgaactggatgactcagggacctacatctgcaatgtgtca
gagagtgtgaatgaccatcgagatgaaaaggccatcaatgtcactgtggtcgagagtggc
tacatacgtcttctggaagatctgggccctatacaaattgctgagctgcacagaagccga
acactacaagtggtgtttgaagcctacccaccgcccactgtgctgtggttcaaggacaac
cgtaccctgggcgattccagcgcaggcgagatcgccttgtccacgcgcaatgtgtcggag
acccggtatgtgtcagacctgacgctggtgcgggtgaaggtggcagaggctggctactac
accatgcgggccttccatgaggatgctgaggccaaactttccttcaagctgcaggtcaat
gtccctgttcgtgtgctggagctgagtgagagtcaccctgccaatggggagcagacagtt
cgttgtcgcggccgaggcatgccccagccaaatgtcacctggtctacctgcagagacctc
aaaaggtgtccacgtgagctgccgcccataccactggggaacagttccgaggaggaaagt
cagttggagactaatgtgacatactgggcggaggaacaggagtatgaggtggtgagcacg
ttgcgcctgcgccacgtggaccaaccactgtcggtgcgctgcatgctgcacaacccgctg
ggccaggatatgcaggaagttaccgtggtgccacattccctccccttcaaggtggtggtg
atctcagccatcctggccttggtggttctcacagtcatctccctcatcatactcatcatg
ctctggcagaagaagccccgctatgagattcggtggaaggtgattgagtctgtgagctcc
gatggccatgagtacatctatgtggaccccatgcagctgccctacgactccacgtgggaa
ttgccacgggaccagcttgtgcttggacgcaccctcggctctggggccttcgggcaggtg
gtggaggccacagctcatggcctgagccattcacagtccaccatgaaagtggccgtcaag
atgctgaaatccacagcccgcagcagtgagaagcaagccctcatgtcggagttgaagatc
atgagccacctggggccccacctgaacgtggtcaacctgctgggggcctgcaccaaagga
ggccccatctacatcatcaccgagtactgccgctatggcgacctggtggactacctgcac
cgcaacaagcacagcttcctgcagcaccactcggacaagcgccggccgcccagtgcagag
ctctacagcaacgccctgcccgtggggccgcccctgcccagccatgtgtccctgactggg
gagagcgacggtggctacatggacatgagcaaggacgagtcagtggactacgtgcccatg
ctggacatgaaaggagacgtcacatatgcagacattgagtcctccagctacatggcccct
tatgataactacgttccctctgctcctgagaggacctgtcgagccactttgatcaatgag
tctccagtgcttagctacacagacctcgtgggcttcagttaccaagtggccaatggcatg
gaattcctggcttctaagaattgtgttcatcgagacctggcagccaggaacgtgctcatc
tgtgagggcaagctggtcaagatctgtgactttggcttggctagagacatcatgcgggac
tcaaactacatctccaaaggcagtaccttcctgcctctgaagtggatggccccggagagc
atcttcaacagcctctacaccaccctgagcgacgtgtggtccttcgggattcttctctgg
gagatcttcacgttgggtggcaccccttacccggagctgcccatgaatgagcagttctac
aatgccatcaagcgaggttaccgcatggcccagcctgctcacgcctccgacgagatctac
cagatcatgcagaagtgctgggaagagaagtttgaggttcggccccccttctcccaactc
gtgctgcttcttgagagactgcttactgagggttacaaaaagaagtaccagcaggtggat
gaggagtttctgagaagtgaccacccagccatccttcggtcccaagcccgcttgcctgga
ttccacagcctccgatctcctctggacaccagctctgtcctctatactgctgtgcagccc
agcgagggtgacaatgactatatcatccccctgcctgaccccaaacctgagactgctgat
gaaggtccactggagggttcccccagcctggccagctccaccctgaatgaagtcaacacc
tcctctaccatctcctgtgacagtcctcttgaccctcaagaagaaccagagccagagtcc
ctgcccaagccccccgtggaggcccagctggagcttgagccaccaatggaaacaggctgc
cctgggcctcggatcgaagcagaggacagctttctgtag

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