Sciurus carolinensis (gray squirrel): 124987010 Help Entry 124987010         CDS       T08117                                  Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism ncar  Sciurus carolinensis (gray squirrel) Pathway ncar00230   Purine metabolism ncar01100   Metabolic pathways ncar01522   Endocrine resistance ncar04015   Rap1 signaling pathway ncar04020   Calcium signaling pathway ncar04022   cGMP-PKG signaling pathway ncar04024   cAMP signaling pathway ncar04062   Chemokine signaling pathway ncar04072   Phospholipase D signaling pathway ncar04081   Hormone signaling ncar04082   Neuroactive ligand signaling ncar04114   Oocyte meiosis ncar04211   Longevity regulating pathway ncar04213   Longevity regulating pathway - multiple species ncar04261   Adrenergic signaling in cardiomyocytes ncar04270   Vascular smooth muscle contraction ncar04371   Apelin signaling pathway ncar04540   Gap junction ncar04611   Platelet activation ncar04713   Circadian entrainment ncar04714   Thermogenesis ncar04723   Retrograde endocannabinoid signaling ncar04724   Glutamatergic synapse ncar04725   Cholinergic synapse ncar04727   GABAergic synapse ncar04750   Inflammatory mediator regulation of TRP channels ncar04911   Insulin secretion ncar04912   GnRH signaling pathway ncar04913   Ovarian steroidogenesis ncar04914   Progesterone-mediated oocyte maturation ncar04915   Estrogen signaling pathway ncar04916   Melanogenesis ncar04918   Thyroid hormone synthesis ncar04921   Oxytocin signaling pathway ncar04922   Glucagon signaling pathway ncar04923   Regulation of lipolysis in adipocytes ncar04925   Aldosterone synthesis and secretion ncar04926   Relaxin signaling pathway ncar04927   Cortisol synthesis and secretion ncar04928   Parathyroid hormone synthesis, secretion and action ncar04934   Cushing syndrome ncar04935   Growth hormone synthesis, secretion and action ncar04970   Salivary secretion ncar04971   Gastric acid secretion ncar04972   Pancreatic secretion ncar04976   Bile secretion ncar05032   Morphine addiction ncar05163   Human cytomegalovirus infection ncar05166   Human T-cell leukemia virus 1 infection ncar05200   Pathways in cancer ncar05207   Chemical carcinogenesis - receptor activation ncar05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ncar00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     124987010  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     124987010    04371 Apelin signaling pathway     124987010    04020 Calcium signaling pathway     124987010    04072 Phospholipase D signaling pathway     124987010    04024 cAMP signaling pathway     124987010    04022 cGMP-PKG signaling pathway     124987010   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     124987010    04081 Hormone signaling     124987010  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     124987010   09144 Cellular community - eukaryotes    04540 Gap junction     124987010  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     124987010    04062 Chemokine signaling pathway     124987010   09152 Endocrine system    04911 Insulin secretion     124987010    04922 Glucagon signaling pathway     124987010    04923 Regulation of lipolysis in adipocytes     124987010    04912 GnRH signaling pathway     124987010    04913 Ovarian steroidogenesis     124987010    04915 Estrogen signaling pathway     124987010    04914 Progesterone-mediated oocyte maturation     124987010    04921 Oxytocin signaling pathway     124987010    04926 Relaxin signaling pathway     124987010    04935 Growth hormone synthesis, secretion and action     124987010    04918 Thyroid hormone synthesis     124987010    04928 Parathyroid hormone synthesis, secretion and action     124987010    04916 Melanogenesis     124987010    04925 Aldosterone synthesis and secretion     124987010    04927 Cortisol synthesis and secretion     124987010   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     124987010    04270 Vascular smooth muscle contraction     124987010   09154 Digestive system    04970 Salivary secretion     124987010    04971 Gastric acid secretion     124987010    04972 Pancreatic secretion     124987010    04976 Bile secretion     124987010   09156 Nervous system    04724 Glutamatergic synapse     124987010    04727 GABAergic synapse     124987010    04725 Cholinergic synapse     124987010    04723 Retrograde endocannabinoid signaling     124987010   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     124987010   09149 Aging    04211 Longevity regulating pathway     124987010    04213 Longevity regulating pathway - multiple species     124987010   09159 Environmental adaptation    04713 Circadian entrainment     124987010    04714 Thermogenesis     124987010  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     124987010    05207 Chemical carcinogenesis - receptor activation     124987010   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     124987010    05163 Human cytomegalovirus infection     124987010   09165 Substance dependence    05032 Morphine addiction     124987010   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     124987010   09167 Endocrine and metabolic disease    04934 Cushing syndrome     124987010   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     124987010 Enzymes [BR:ncar01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      124987010 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  124987010 NCBI-ProteinID:  XP_047411839 LinkDB All DBs Position 6:5940883..6314369 Genome browser AA seq 1095 aa AA seqDB search MWQEAMRRRRYLRDRAEAAAAAAAGGGDGLQRSRDWLYESYYCMSQQHPLIVFLLLIVMG ACLALLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRVFSLVIWIC LVAMGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAVIASVLTSSSHTIVLSVC LSATPGAKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFE KRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADI VGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAK NCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHM EAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHL FRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQ NRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKILEKEYRATA LPAFKYYVTCACLIFFCIFIVQILVLPKTTVLGVSFGAAFLSLACILFVCFAGQLLQCSK KASASLLWLLKSSGIIANRPWPRISLTVVTTAIILTMAVFNMFFLSDSEETVLPTANTSN TSFPASSNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVGYNTI LLHTHAHVLDDYSQVLFERPGIWKDLKTMGSVSLSIFFITLLVLGRQNEYYCRLDFLWKN KFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDF KEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPS QEHAQEPERQYLHIGTMVEFAFALVAKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKP QYDIWGNTVNVASRMDSTGVLDKIQVTEETSLVLQTLGYTCTCRGIINVKGKGDLKTYFV NTEMSRSLSQSNVAS NT seq 3288 nt NT seq  +upstreamnt  +downstreamnt atgtggcaggaggcgatgcggcgccgccgctacctgcgggaccgcgccgaggcggcggcg gcggcggcggcgggcggcggcgacgggctgcagcggtcccgggactggctgtacgagtcc tactactgcatgagccagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggc gcctgcctcgccctgctcgctgtcttcttcgcgctcggactggaagttgaagaccacgtg gcctttttaataacagttccaacggcactggcgattttcttcgcgatattcatccttgtc tgcattgagtctgtgtttaagaagctgctgcgtgtgttctccttggtgatctggatatgt cttgttgccatggggtacttgttcatgtgcttcggaggcaccgtctctccctgggaccag gtgtccttcttcctcttcatcatcttcgtggtgtacaccatgctgcccttcaacatgcgg gatgccgtcatcgccagcgtcctcacctcctcgtcccacaccattgtgctcagcgtctgc ctgtctgcgacgccgggggccaaggagcacctggtctggcagatcctggccaacgtgatc attttcatctgtgggaacctggcaggagcctaccataagcacctcatggaacttgctctg cagcaaacatatcaggacacgtgcaattgcatcaagtcccggatcaagctggaatttgaa aaacgtcaacaggagcggcttctactgtccttgctgccagctcacatcgccatggaaatg aaagccgagatcatccagaggctgcaaggccccaaagcaggccaaatggaaaacacgaac aacttccacaacctgtacgtcaaacgacacaccaacgtgagcatcttgtacgctgacatc gtgggcttcacgcggctggccagcgactgctccccgggggagctggtgcacatgctgaat gagctcttcgggaagttcgaccagatcgccaaggagaatgaatgcatgaggattaaaatt ctcggagattgctattactgtgtgtctggacttcccatctccctccctaaccatgccaag aactgcgtgaaaatggggctggatatgtgtgaagccataaagaaagtgagagatgctacc ggagttgatatcaacatgcgcgtgggagtgcattcagggaacgtcctgtgcggtgtgatc ggtctgcagaagtggcagtatgacgtgtggtcacacgacgtcaccctggccaaccacatg gaagctggaggggtccctggacgagttcacatttcctctgtcaccttggagcacttgaat ggcgcttataaagtggaggagggagatggtgacattagggacccatatttaaaacagcac ctggtgaaaacctacttcgtaatcaaccccaagggagagcggcggagtccccagcacctc ttcaggcctcgccacaccctggacggagccaagatgagggcctctgttcgaatgacccgg tacttggagtcgtggggggcagccaaaccctttgcacatctgcatcacagagacagcatg accactgagaacggcaagatcagcaccacggatgtaccgatgggtcagcataattttcaa aaccgcaccttaagaaccaaatcacaaaagaaaagatttgaagaagaattgaatgaaagg atgatccaagcaattgatggaatcaacgcacaaaagcaatggctcaagtctgaagacatt cagagaatctcactgcttttctataacaaaattctagagaaagaataccgagccacagca ctgccagctttcaagtactacgtgacttgcgcctgcctcatcttcttctgcatcttcatc gtgcagattcttgtgttgcccaagacgaccgtcctcggcgtgtcctttggagctgcgttc ctctctctcgcctgcatcctttttgtctgctttgctgggcagcttttgcaatgcagcaaa aaggcctccgcctccctcctgtggctcttgaagtcgtcgggcatcattgccaaccgtccc tggccgcggatctccctcacggtcgtcaccacagccatcatactcaccatggccgtgttc aacatgtttttcctgagtgactcggaggagacagtccttcccacggccaacacgtccaac acaagctttcctgcctcgagtaaccaagcagcgattctgcgtgcacaaaatttgtttttc ctcccgtacttcatatacagctgcattctggggctgatatcctgctccgtgttcctgagg gtgaactacgagttgaaaatgctgatcatgatggtggccttggtgggctacaacaccatc ctgctgcacacccacgcccacgtcctggacgactacagccaggtcctgtttgaaagacca ggcatttggaaggacctgaagaccatgggctcggtgtccctctccatcttcttcatcacg ctgctcgttctgggtagacagaatgaatattactgtaggttagacttcttgtggaagaac aagttcaaaaaagagcgggaggagatagaaaccatggagaacctgaaccgcgtgctgctg gagaacgtgcttcccgcgcatgtggcggagcacttcctggccaggagcctgaagaacgag gagttgtaccaccagtcatatgactgcgtctgcgtcatgtttgcctccattccggacttc aaagaattctatacggagtcagacgtgaacaaggagggcttggagtgcctccggctcctg aacgagatcatcgcggactttgatgatctgctgtccaagccgaaattcagcggcgttgaa aagatcaagaccatcggaagcacgtacatggcggccacgggtctgagcgccgtgcccagc caggagcacgctcaggagccggagcggcagtacctgcacataggcaccatggtggagttt gcgtttgccctggtggccaagctggacgccatcaacaagcactccttcaatgacttcaag ctgcgagtgggcattaaccatggacctgtaatagctggtgtcatcggagcccagaagcca caatatgacatctggggcaacaccgtcaatgtggccagtaggatggacagcactggagtc ctggacaaaatacaggtcaccgaggagaccagcctcgttctacagacactcgggtatacc tgcacgtgccggggaataatcaacgtgaaagggaagggggacctgaagacgtactttgta aacacggaaatgtcacggtccctctcccagagcaatgtggcgtcctga

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