KEGG   Sciurus carolinensis (gray squirrel): 124988890
Entry
124988890         CDS       T08117                                 
Name
(RefSeq) tumor necrosis factor
  KO
K03156  tumor necrosis factor superfamily, member 2
Organism
ncar  Sciurus carolinensis (gray squirrel)
Pathway
ncar01523  Antifolate resistance
ncar04010  MAPK signaling pathway
ncar04060  Cytokine-cytokine receptor interaction
ncar04061  Viral protein interaction with cytokine and cytokine receptor
ncar04064  NF-kappa B signaling pathway
ncar04071  Sphingolipid signaling pathway
ncar04150  mTOR signaling pathway
ncar04210  Apoptosis
ncar04217  Necroptosis
ncar04350  TGF-beta signaling pathway
ncar04380  Osteoclast differentiation
ncar04612  Antigen processing and presentation
ncar04620  Toll-like receptor signaling pathway
ncar04621  NOD-like receptor signaling pathway
ncar04622  RIG-I-like receptor signaling pathway
ncar04625  C-type lectin receptor signaling pathway
ncar04640  Hematopoietic cell lineage
ncar04650  Natural killer cell mediated cytotoxicity
ncar04657  IL-17 signaling pathway
ncar04660  T cell receptor signaling pathway
ncar04664  Fc epsilon RI signaling pathway
ncar04668  TNF signaling pathway
ncar04920  Adipocytokine signaling pathway
ncar04930  Type II diabetes mellitus
ncar04931  Insulin resistance
ncar04932  Non-alcoholic fatty liver disease
ncar04933  AGE-RAGE signaling pathway in diabetic complications
ncar04936  Alcoholic liver disease
ncar04940  Type I diabetes mellitus
ncar05010  Alzheimer disease
ncar05014  Amyotrophic lateral sclerosis
ncar05020  Prion disease
ncar05022  Pathways of neurodegeneration - multiple diseases
ncar05132  Salmonella infection
ncar05133  Pertussis
ncar05134  Legionellosis
ncar05135  Yersinia infection
ncar05140  Leishmaniasis
ncar05142  Chagas disease
ncar05143  African trypanosomiasis
ncar05144  Malaria
ncar05145  Toxoplasmosis
ncar05146  Amoebiasis
ncar05152  Tuberculosis
ncar05160  Hepatitis C
ncar05161  Hepatitis B
ncar05163  Human cytomegalovirus infection
ncar05164  Influenza A
ncar05165  Human papillomavirus infection
ncar05166  Human T-cell leukemia virus 1 infection
ncar05168  Herpes simplex virus 1 infection
ncar05169  Epstein-Barr virus infection
ncar05170  Human immunodeficiency virus 1 infection
ncar05171  Coronavirus disease - COVID-19
ncar05205  Proteoglycans in cancer
ncar05310  Asthma
ncar05321  Inflammatory bowel disease
ncar05322  Systemic lupus erythematosus
ncar05323  Rheumatoid arthritis
ncar05330  Allograft rejection
ncar05332  Graft-versus-host disease
ncar05410  Hypertrophic cardiomyopathy
ncar05414  Dilated cardiomyopathy
ncar05417  Lipid and atherosclerosis
ncar05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ncar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    124988890
   04350 TGF-beta signaling pathway
    124988890
   04064 NF-kappa B signaling pathway
    124988890
   04668 TNF signaling pathway
    124988890
   04071 Sphingolipid signaling pathway
    124988890
   04150 mTOR signaling pathway
    124988890
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    124988890
   04061 Viral protein interaction with cytokine and cytokine receptor
    124988890
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    124988890
   04217 Necroptosis
    124988890
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    124988890
   04620 Toll-like receptor signaling pathway
    124988890
   04621 NOD-like receptor signaling pathway
    124988890
   04622 RIG-I-like receptor signaling pathway
    124988890
   04625 C-type lectin receptor signaling pathway
    124988890
   04650 Natural killer cell mediated cytotoxicity
    124988890
   04612 Antigen processing and presentation
    124988890
   04660 T cell receptor signaling pathway
    124988890
   04657 IL-17 signaling pathway
    124988890
   04664 Fc epsilon RI signaling pathway
    124988890
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    124988890
  09158 Development and regeneration
   04380 Osteoclast differentiation
    124988890
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    124988890
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    124988890
   05170 Human immunodeficiency virus 1 infection
    124988890
   05161 Hepatitis B
    124988890
   05160 Hepatitis C
    124988890
   05171 Coronavirus disease - COVID-19
    124988890
   05164 Influenza A
    124988890
   05168 Herpes simplex virus 1 infection
    124988890
   05163 Human cytomegalovirus infection
    124988890
   05169 Epstein-Barr virus infection
    124988890
   05165 Human papillomavirus infection
    124988890
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    124988890
   05135 Yersinia infection
    124988890
   05133 Pertussis
    124988890
   05134 Legionellosis
    124988890
   05152 Tuberculosis
    124988890
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    124988890
   05144 Malaria
    124988890
   05145 Toxoplasmosis
    124988890
   05140 Leishmaniasis
    124988890
   05142 Chagas disease
    124988890
   05143 African trypanosomiasis
    124988890
  09163 Immune disease
   05310 Asthma
    124988890
   05322 Systemic lupus erythematosus
    124988890
   05323 Rheumatoid arthritis
    124988890
   05321 Inflammatory bowel disease
    124988890
   05330 Allograft rejection
    124988890
   05332 Graft-versus-host disease
    124988890
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    124988890
   05014 Amyotrophic lateral sclerosis
    124988890
   05020 Prion disease
    124988890
   05022 Pathways of neurodegeneration - multiple diseases
    124988890
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    124988890
   05418 Fluid shear stress and atherosclerosis
    124988890
   05410 Hypertrophic cardiomyopathy
    124988890
   05414 Dilated cardiomyopathy
    124988890
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    124988890
   04940 Type I diabetes mellitus
    124988890
   04936 Alcoholic liver disease
    124988890
   04932 Non-alcoholic fatty liver disease
    124988890
   04931 Insulin resistance
    124988890
   04933 AGE-RAGE signaling pathway in diabetic complications
    124988890
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    124988890
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ncar04052]
    124988890
   00536 Glycosaminoglycan binding proteins [BR:ncar00536]
    124988890
Cytokines and neuropeptides [BR:ncar04052]
 Cytokines
  Tumor necrosis fators
   124988890
Glycosaminoglycan binding proteins [BR:ncar00536]
 Heparan sulfate / Heparin
  Cytokines
   124988890
SSDB
Motif
Pfam: TNF DUF956
Other DBs
NCBI-GeneID: 124988890
NCBI-ProteinID: XP_047414667
LinkDB
Position
7:complement(122912119..122914830)
AA seq 232 aa
MSTESMIRDVELAEEALPKKPWGPQGSTRCLCLSLFSFLLVAAATTLFCLLHFGVIGPQR
EESQNNPSLSAQAQMLTLRSSSQNMNDKPVAHVVANQTEEQLQWLSRRANALLANGMELI
DNQLVVPADGLYLIYSQVLFKGQGCSSYVLLTHTVSRFAVSYQDKVNLLSAIKSPCPKES
LEGAEFKPWYEPIYLGGVFELQKGDRLSAEVNLPSYLDFAESGQVYFGVIAL
NT seq 699 nt   +upstreamnt  +downstreamnt
atgagcactgaaagcatgatccgggacgtggagctggctgaggaggcgctccccaagaag
ccatggggcccccagggctccacccgttgcctgtgcctcagtctcttctccttcctgctt
gtggcagcagccaccacgctcttctgcctgctgcactttggagtgatcggcccccagagg
gaagagtcccagaataacccctctctcagtgcccaggcccagatgctcacactcagatca
tcttctcaaaacatgaatgacaagcctgtagcccatgttgtagcaaaccaaaccgaggag
cagctgcagtggctgagccgacgtgccaatgctctcctggccaatggcatggagctgata
gacaaccagctggtggtacctgcagacgggctatacctcatctactcccaggtcctcttc
aagggccaaggctgctcctcctacgtgctcctcactcacactgtcagccgctttgctgta
tcttaccaggacaaggtcaacctactctctgccatcaagagcccctgcccaaaggaaagc
ctggagggggctgagttcaagccctggtatgagcccatctatctgggaggggtcttcgag
ctgcagaagggtgatcgactcagtgctgaggtcaacctgcccagctatctcgactttgct
gagtccggacaggtctactttggggtcattgccctgtga

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