Sciurus carolinensis (gray squirrel): 124990345 Help Entry 124990345         CDS       T08117                                  Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism ncar  Sciurus carolinensis (gray squirrel) Pathway ncar00230   Purine metabolism ncar01100   Metabolic pathways ncar01522   Endocrine resistance ncar04015   Rap1 signaling pathway ncar04020   Calcium signaling pathway ncar04022   cGMP-PKG signaling pathway ncar04024   cAMP signaling pathway ncar04062   Chemokine signaling pathway ncar04072   Phospholipase D signaling pathway ncar04081   Hormone signaling ncar04082   Neuroactive ligand signaling ncar04114   Oocyte meiosis ncar04211   Longevity regulating pathway ncar04213   Longevity regulating pathway - multiple species ncar04261   Adrenergic signaling in cardiomyocytes ncar04270   Vascular smooth muscle contraction ncar04371   Apelin signaling pathway ncar04540   Gap junction ncar04611   Platelet activation ncar04713   Circadian entrainment ncar04714   Thermogenesis ncar04720   Long-term potentiation ncar04723   Retrograde endocannabinoid signaling ncar04724   Glutamatergic synapse ncar04725   Cholinergic synapse ncar04727   GABAergic synapse ncar04750   Inflammatory mediator regulation of TRP channels ncar04911   Insulin secretion ncar04912   GnRH signaling pathway ncar04913   Ovarian steroidogenesis ncar04914   Progesterone-mediated oocyte maturation ncar04915   Estrogen signaling pathway ncar04916   Melanogenesis ncar04918   Thyroid hormone synthesis ncar04921   Oxytocin signaling pathway ncar04923   Regulation of lipolysis in adipocytes ncar04925   Aldosterone synthesis and secretion ncar04926   Relaxin signaling pathway ncar04927   Cortisol synthesis and secretion ncar04928   Parathyroid hormone synthesis, secretion and action ncar04934   Cushing syndrome ncar04935   Growth hormone synthesis, secretion and action ncar04970   Salivary secretion ncar04971   Gastric acid secretion ncar04972   Pancreatic secretion ncar04976   Bile secretion ncar05032   Morphine addiction ncar05142   Chagas disease ncar05146   Amoebiasis ncar05163   Human cytomegalovirus infection ncar05166   Human T-cell leukemia virus 1 infection ncar05200   Pathways in cancer ncar05207   Chemical carcinogenesis - receptor activation ncar05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ncar00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     124990345  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     124990345    04371 Apelin signaling pathway     124990345    04020 Calcium signaling pathway     124990345    04072 Phospholipase D signaling pathway     124990345    04024 cAMP signaling pathway     124990345    04022 cGMP-PKG signaling pathway     124990345   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     124990345    04081 Hormone signaling     124990345  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     124990345   09144 Cellular community - eukaryotes    04540 Gap junction     124990345  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     124990345    04062 Chemokine signaling pathway     124990345   09152 Endocrine system    04911 Insulin secretion     124990345    04923 Regulation of lipolysis in adipocytes     124990345    04912 GnRH signaling pathway     124990345    04913 Ovarian steroidogenesis     124990345    04915 Estrogen signaling pathway     124990345    04914 Progesterone-mediated oocyte maturation     124990345    04921 Oxytocin signaling pathway     124990345    04926 Relaxin signaling pathway     124990345    04935 Growth hormone synthesis, secretion and action     124990345    04918 Thyroid hormone synthesis     124990345    04928 Parathyroid hormone synthesis, secretion and action     124990345    04916 Melanogenesis     124990345    04925 Aldosterone synthesis and secretion     124990345    04927 Cortisol synthesis and secretion     124990345   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     124990345    04270 Vascular smooth muscle contraction     124990345   09154 Digestive system    04970 Salivary secretion     124990345    04971 Gastric acid secretion     124990345    04972 Pancreatic secretion     124990345    04976 Bile secretion     124990345   09156 Nervous system    04724 Glutamatergic synapse     124990345    04727 GABAergic synapse     124990345    04725 Cholinergic synapse     124990345    04720 Long-term potentiation     124990345    04723 Retrograde endocannabinoid signaling     124990345   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     124990345   09149 Aging    04211 Longevity regulating pathway     124990345    04213 Longevity regulating pathway - multiple species     124990345   09159 Environmental adaptation    04713 Circadian entrainment     124990345    04714 Thermogenesis     124990345  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     124990345    05207 Chemical carcinogenesis - receptor activation     124990345   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     124990345    05163 Human cytomegalovirus infection     124990345   09174 Infectious disease: parasitic    05146 Amoebiasis     124990345    05142 Chagas disease     124990345   09165 Substance dependence    05032 Morphine addiction     124990345   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     124990345   09167 Endocrine and metabolic disease    04934 Cushing syndrome     124990345   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     124990345 Enzymes [BR:ncar01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      124990345 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF6688 Motif Other DBs NCBI-GeneID:  124990345 NCBI-ProteinID:  XP_047416249 LinkDB All DBs Position 8:103312190..103465937 Genome browser AA seq 1118 aa AA seqDB search MAGAPRGQGGGGGGAGEPGGAERAAGPGGRRGFRACGEEFACPELEALFRGYTLRLEQAA TLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQ QVGQLALLFSLTFALLCCPFALGGPARGSAGAAAGSAAAEQGVWQLLLVTFVSYALLPVR SLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQR KAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHD NVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGL TQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWS NDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVPSH RRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALR TASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLKYKHVEREQK YHQLQDEYFTSAVVLALILAALFGLVYLLMIPQSVAVLLLLVFCICFLVACVLYLHITRV QCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSQSNSSLVVLAAGGRRTVLP ALPCESAHHALLCCLVGTLPLAIFLRVSSLPKMILLSGLTTSYILVLELSGYTKAEGGGV SGRSYEPIMAILLFSCTLALHARQVDVRLRLDYLWAAQAEEERDDMERVKLDNKRILFNL LPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEI IADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTRAKKSISSHLSTLADFAIEMFD VLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQV TEEVHRLLRRCAYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSHRSLHLERKMCSYGRAG GQARRPPLCPAAGPPVRAGLPPVPTGQYLPPAAAGKEA NT seq 3357 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccaaggcggcggcggaggcggcgcgggcgagcccgggggc gccgagcgggcggccgggccgggcggccggcgcgggttccgggcgtgcggcgaggagttc gcgtgccccgagctggaggcgctgttccgcggctacactctgcggctggagcaggcagcc acgctgaaggctctggctgtgctcagcctactggcgggcgcgctggcactggccgagttg ctaggcgcgccggggcccgcgcccggcctggccaaggggtcgcacccggtgcactgcgtc ctctttttggcgctgcttgtggtcaccaatgtccggtccctgcaggtgcctcagctgcag caggtcggtcagctggcgctgctcttcagtctcaccttcgcgctgctgtgctgccccttt gcactgggcggccccgccaggggctctgccggggcggctgcggggtcggccgcagccgaa cagggggtttggcagcttcttttggtcaccttcgtttcctatgccttgctgcccgtgcgc agcctgctggccatcggctttgggcttgtggtggccgcctcgcacttactggttacagcc accttggtcccagccaagcgcccgcgtctctggaggacgcttggcgccaatgccctgctc ttcgtgggtgtgaacatgtatggcgtcttcgtgcggatcctgactgagcgctctcagagg aaggcctttctgcaggcccggagctgcatcgaggatcggctgcggctggaggatgaaaac gagaagcaggagcggctgcttatgagcctccttccccggaatgtcgccatggagatgaag gaggacttcttgaagccccctgagaggattttccacaagatttacatccagaggcatgac aatgtgagcatcctgtttgccgacattgtgggcttcacaggcttggcatcccagtgcacg gcccaggagctggtgaaactgctcaatgaactctttggcaagttcgatgagttagccacg gagaaccactgtcgtcgcatcaagatccttggggactgctactactgtgtgtcaggcctt acccagcccaagactgaccatgcccactgctgtgtggagatggggcttgacatgattgac accatcacgtctgtggctgaggccactgaggtggacctgaacatgcgtgtggggctacac accggcagggtcctctgtggtgttctgggcctgcgcaagtggcaatacgacgtgtggtcc aatgatgtgaccctggccaacgtcatggaggctgctggcctgcctgggaaggttcatatc acaaagacaacccttgcgtgcttgaatggggactatgaggtagagccaggccatggacat gagaggaacagctttctgaaaactcataacatcgagaccttctttattgtgccatcccat cggagaaagatatttccaggcctgattctctcagatataaagccggccaagaggatgaag tttaagactgtctgctacctgctggtacagctcatgcactgccggaagatgttcaaggct gagatccccttctccaatgtcatgacctgtgaagacgatgacaagcggagggcgttgaga acagcatcagaaaaactgagaaaccgctcgtctttctctacaaatgtggtctacaccaca ccgggcacgcgtgtcaataggtacatcagccgcctcctggaagcccgtcagacggagctg gagatggcggatctgaacttctttaccttgaagtacaaacatgttgaacgggaacaaaag taccaccagcttcaggacgagtatttcaccagcgctgtcgtccttgccctcatcctggct gccttatttggccttgtctaccttcttatgatcccacagagtgtggccgtcctgctcctg ctggtgttctgtatctgcttcctggtggcctgtgtcctctacctgcacatcacccgggtc cagtgttttccagggtgcctgacgattcagattcgtaccgtcttgtgcatattcatagtg gtcttaatctattctgtagcccaaggatgtgtggtgggctgcctaccctgggcctggagc tcccagtccaacagctccctggtggtccttgcggctgggggccggcgcactgtgttgcct gctctgccctgcgagtctgcacatcacgccctgctctgctgcctggtgggtaccctcccg ctagccatattcctgcgggtgtcctccttgccaaagatgatcctgctgtctgggctcacc acatcctacatcctcgttctggagctcagcggatacaccaaggccgagggcggtggtgtc tctgggcgcagctacgagccgatcatggccatcctgctgttctcatgcacgctggccctg catgccaggcaggtggacgtgaggctgcggctggactacctctgggcagcacaggcagaa gaggagcgagatgatatggagagggtaaagctggacaacaagaggatactctttaacctc ctgccagcccacgttgcacagcacttcctcatgtccaatccccggaatatggacctctac taccagtcctactcccaggtgggcgtcatgtttgcctccattcccaacttcaatgacttc tacatcgagctggatggcaacaacatgggggtggagtgcctgcgactcctcaacgagatc atcgctgactttgatgagctcatggacaaagacttttacaaggatctagagaagatcaag accattgggagcacctacatggctgcagtggggctggcgcccacagcaggaaccagggct aagaaatccatctcctcccatctcagcacactggctgactttgctattgagatgtttgac gtcttggatgaaatcaactaccagtcgtacaatgacttcgtcctccgagttggtatcaac gttggccctgtggtggctggagtgattggtgctcgtaggccccagtacgacatctgggga aacacagtcaatgtggccagtcggatggacagcaccggagtccaaggcaggatccaggtg actgaggaggtgcaccgtctgctgaggaggtgtgcctaccacttcgtgtgccgaggcaaa gtcagtgtcaaaggcaagggagagatgctgacatacttcctagaaggcaggactgatgga aatggctcccacaggtctcttcacttggagcgcaagatgtgttcttatgggagagctgga ggccaggccaggcggcccccactgtgccccgcagcaggcccaccagtcagggctgggctg cccccagttcccacaggccagtacctgccacctgcagcagcggggaaggaagcttag

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