KEGG   Neisseria canis: NCTC10296_01865
Entry
NCTC10296_01865   CDS       T06799                                 
Symbol
acrB
Name
(GenBank) antibiotic resistance efflux pump component
  KO
K18138  multidrug efflux pump
Organism
nci  Neisseria canis
Pathway
nci01501  beta-Lactam resistance
nci01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:nci00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    NCTC10296_01865 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    NCTC10296_01865 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:nci02000]
    NCTC10296_01865 (acrB)
   01504 Antimicrobial resistance genes [BR:nci01504]
    NCTC10296_01865 (acrB)
Transporters [BR:nci02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   NCTC10296_01865 (acrB)
Antimicrobial resistance genes [BR:nci01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    NCTC10296_01865 (acrB)
SSDB
Motif
Pfam: ACR_tran MMPL SecD_SecF_C DUF3999 Patched
Other DBs
NCBI-ProteinID: VEF02574
UniProt: A0A448D9Y6
LinkDB
Position
1:complement(1948782..1951985)
AA seq 1067 aa
MAKFFIDRPIFAWVIAIFVIIAGVLSITKLPVSQYPSVGAPTITLNATYPGASAQVMEDS
VLSIIERSMNGVEGLDYISTNATSNGSGSVSLTFTPETNEDLAQVNVQNKLAEVTALLPA
TVQQNGVTISKSRSNFLMVLMMSSETMTTEDIADYVERNIKPEIQRVEGVGEARLFGSQR
AMRVWVDPKKLQNYNLSFADVSSAINSQNAQLSVGTMGALPSRQGQTIAATITAQGQLST
PEEFGNIILRSTTGGANVYLRDVAKIELGSQDYSTATRLNGKPAVGMAVMLSTSGNAMAT
AAAVREKMDQLQRYFPNDMKWSAPYDTSKFVSISIEKVVHTLLEAIVLVFIVMYLFLQNI
RYTLIPTIVVPISLLGAFASIWYLGMSINVLTMFAMVLVIGIVVDDAIVVVENVERIMAE
EGLPPREATKKAMGQISGAVIGITAVLISVFVPLAMFSGATGNIYKQFALTMAIAIAFSA
FFALSLTPALCAAMLKPIPKGHHEEKKGFFGWFNRKFSSGTHSYEGWVGRFLNKAGRMMI
VYAALVVVAGVVFLRIPTSFLPEEDQGSLMMMVQLPSGATKERTDATLAVANNVIMSMPE
VENFIGVSGFSFAGSGQNMGFGFITLKDWSERKAAGSDAASVAGKITGALMGSVRDGFAM
VLNPPAIMELGTSSGFEMYLQDRNNSGHDALLAKRNELIAKMRQNPMFDAQNVRASGLED
APQLKINIDRQAAAAQGIDFSNIRSVLSAAIGSSYVNDFPNQGRLQRVIVQADASARMQP
DDILALTVTNKQGIAVPLSTIATAAWQNGMEQSVRFNGYPAMKISGAASSGYSSGEVMAE
VQRMVDEMEGYSLEWSGQSREEAKGSAQTVLLYTFAILAVFLALAALYESWSIPLAVILV
VPLGFLGVVLGVSGRNLLGMAFGVPPAYLNDIYFQVGLITVIGLSAKNAILIIEFAKDLQ
AEGKGVIAAALEAAHLRFRPIIMTSFAFILGVVPLYIASGASSASQRAIGTTVLWGMLIG
TVLAVFLVPVFYVVVRKLFKGGGQKPELAASSGTSAVLVDERGTQRD
NT seq 3204 nt   +upstreamnt  +downstreamnt
atggctaagttttttatcgaccgtcccatttttgcttgggtaattgcgattttcgtgatt
attgcaggtgttttatccataaccaaattaccggtttcccaatatccttcggtaggcgcg
ccgaccattacactgaacgccacttatcccggcgcatcggcacaagtaatggaagacagc
gtattgtcgattatcgagcgcagcatgaacggcgtggaaggcttggattatatatctacc
aacgccacgtcgaacggcagcgggtcggtaagcctgactttcacgccggaaaccaatgaa
gatttggcacaggtgaatgtgcagaataaattggcggaagttacagccttattgccggca
accgtacagcaaaacggtgtaactatctccaaatcccgttccaactttttgatggtatta
atgatgtcttccgaaaccatgaccacggaagacatcgcggattatgtggaacgcaatatc
aaacccgaaatccaacgtgtcgaaggcgtgggcgaagcccgactgtttggttcgcagcgt
gcgatgcgggtgtgggttgatcccaaaaagctgcaaaactacaacttgtcgtttgcagat
gtatcttctgccatcaattcgcagaatgcacagctttcagtgggcacaatgggtgcactg
ccttcccggcaaggccaaacgattgcggctactatcacggcgcaaggacaattgagcaca
cccgaagaattcggcaatattattctccgctcgacaacaggcggtgcgaatgtatatttg
agggatgtggccaaaatcgaattgggaagtcaggattattcaacagccaccagactgaac
ggcaaacctgcggtgggtatggcggttatgctttcaaccagcggcaacgctatggctacg
gcggcggcggttcgtgaaaaaatggatcagctgcaacgctatttcccaaacgatatgaaa
tggtcggcaccttacgatacttccaagtttgtcagcatctcaattgaaaaagtggtgcac
acgcttctggaagccattgtgctggtgtttattgtgatgtacctcttcctgcaaaacatc
cgctatacgttgattccgaccattgttgtgccgatttctttattgggtgcgtttgcttcg
atttggtatttgggcatgtcgataaacgtgttaacgatgtttgcgatggtgctggttatc
ggcatcgtggtggatgatgccattgttgtggtggaaaacgtagagcggattatggcagaa
gaaggcctgcctccgagagaagctactaaaaaggctatggggcagatttcgggcgccgtt
atcggtatcacggctgtgttgatttccgtgtttgtgcctttggcaatgttcagcggagct
accggcaatatctacaaacaatttgcattaaccatggcgattgccattgcattctcggct
ttctttgctctttctctcacaccggctttgtgtgcggctatgctcaagccgataccgaaa
ggccatcatgaagagaaaaaaggctttttcggttggttcaaccgaaaattcagcagcggc
acacacagttatgaaggctgggttggcagattcttaaacaaagccggccgtatgatgatt
gtttacgcggctttggtggtagtggccggtgtcgtgtttctccgtattcctacatcattc
ttaccggaagaagatcagggtagtttgatgatgatggtgcaacttccttctggagcgacg
aaagagcgtaccgacgcgactttggccgttgcgaataatgtgattatgtcgatgccggaa
gtggaaaatttcattggcgtttccggtttcagctttgcaggttcagggcaaaacatgggt
ttcggttttataacgctcaaagattggagtgagcgcaaggctgcgggcagtgatgcggct
tcggtggccggcaagattaccggtgcattgatgggcagcgtgcgggacggttttgccatg
gtgcttaaccctccggcaattatggagctgggcaccagctcgggttttgaaatgtatttg
caagaccgtaacaacagtggccacgacgcattattggccaaacgcaacgagctgattgcc
aaaatgcggcaaaaccccatgtttgatgcgcaaaatgtgcgtgcttcgggcttggaagac
gcgccgcagctgaagatcaatatcgaccgtcaagccgccgccgcccagggtattgatttt
tccaacatccgctcggtgttgtctgcagcgatcggttcttcttatgtaaacgattttccc
aaccaaggccgtttgcagcgggtgattgtgcaggctgatgcttccgcccgcatgcagccc
gacgatattctggctttaacggtaaccaacaagcaaggcattgctgtgccgctttccacc
attgccacggcagcatggcaaaacggtatggagcaaagtgttcgtttcaacggatatccc
gctatgaaaatcagtggcgcggcatcatccggctactcttcgggtgaggtgatggccgag
gtgcagcgcatggttgacgaaatggaaggttacagtttggaatggagcggccaatcccgc
gaagaagccaaaggcagcgcgcaaactgttttgttgtacacgtttgcgattttggctgtg
tttttggcgctggctgctttgtatgaaagctggtcgattcctttggccgtaattttggta
gtgcctttgggctttttgggcgtggtattgggcgtatccggccgaaatctgctcggtatg
gcttttggtgtgccgcctgcttatctcaacgatatttatttccaggtcggcctgattacg
gtaatcggtttgagcgcgaaaaacgcgattctgattatcgaattcgccaaagatctgcaa
gcggaaggcaagggcgtgattgcagccgcattggaagccgcacacttgcgtttccgcccg
attatcatgacttcttttgcctttattttgggcgtggtgccgctttatattgcatccggt
gccagctcggcgagtcagcgtgcgatcggtacgaccgtattgtggggcatgcttatcggt
acggtattggcggttttcctggtgccggttttctatgtggtggtgcgcaagctgtttaaa
ggcggagggcaaaagcctgaattggcggcttcttccggcacatctgccgtgttggttgac
gaacgtggtacgcagagggattaa

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