Nonomuraea coxensis: Nocox_26185
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Entry
Nocox_26185 CDS
T07466
Symbol
metH
Name
(GenBank) Methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
ncx
Nonomuraea coxensis
Pathway
ncx00270
Cysteine and methionine metabolism
ncx00450
Selenocompound metabolism
ncx00670
One carbon pool by folate
ncx01100
Metabolic pathways
ncx01110
Biosynthesis of secondary metabolites
ncx01230
Biosynthesis of amino acids
ncx04980
Cobalamin transport and metabolism
ncx04981
Folate transport and metabolism
Module
ncx_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
ncx00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
Nocox_26185 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
Nocox_26185 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
Nocox_26185 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
Nocox_26185 (metH)
04980 Cobalamin transport and metabolism
Nocox_26185 (metH)
Enzymes [BR:
ncx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
Nocox_26185 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding
B12-binding_2
CdhD
Motif
Other DBs
NCBI-ProteinID:
QYC42838
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Position
complement(5602731..5606195)
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AA seq
1154 aa
AA seq
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MSISPSFREVLDQRVIVADGAMGTMLQAQDPTLDDFHGHEGCNEVLNVSRPDIVRGVHDA
YFAVGVDCVETNTFGANLAALGEYDIADRVFEYSEAGARIAREAADHWSTPEQPRFVLGS
MGPGTKLPTLGHLPYASLRDAYRDNAAGLIAGGADALIVETCQDLLQVKAAVIGAKRAAE
DSGRDIPIIAQVTIETNGAMLLGSEIGAALTAIEPLGVDVIGLNCATGPAEMSEHLRHLA
RHSRLRLSCMPNAGLPVLTSDGAYYPLSPGELADAHGAFTRDYGLSLVGGCCGTTPEHLR
QVVERVRGKETAPRRPRPEPGVSSLYQSVPFRQDTSFLAIGERCNTNGSKAFREAMLGGR
WDDCVEMAREQARGGAHMLDLCVDYVGRDGVADMKELAFRFATASTLPIMLDSTEPEVLR
AGLEMLGGRAAVNSVNYEDGAGPDSRFQKIMRLVREHGAAVVALTIDEEGQARTADWKVR
VASRLIEDLTTNWGMQVEDIIVDTLTFPIATGQEETRRDGLETIEAIRELKRRYPGVQTT
LGVSNISFGLNPAARMVLNSVFLNECVNAGLDSAIVHASKILPMARIPDEQRQVALDMVY
DRRREGYDPLQRFMDLFEGVDAAALRAGKAEELASLPLWERLKRRIVDGERKGLEADLDT
ALEQRPALEIINEVLLDGMKTVGVLFGSGQMQLPFVLQSAEVMKAAVAHLEPHMERVEGE
TKGRIVLATVKGDVHDIGKNLVDIILSNNGYQVVNLGIKQPVSAILEAADEQKADVIGMS
GLLVKSTVVMKENLEEMNSRGLSDRYPVLLGGAALTRAYVEQDLAELFEGEVRYARDAFE
GLRLMDAFMAVKRGEKGATLPPLRERRVKTGAVLQRTPVEELPARSDVAADNPVPVAPFL
GDRVVKGVSLADYAAFLDERALFLGQWGLKPTRGGEGPGYDELVETEGRPRLRMWLDRIQ
TEGLLEAAVVYGHFPCVSDGDSLVILDDAGGERTRFTFPRQRRDRHLCLSDFFRPKESGE
VDVVGFQVVTMGAKIAQATAELFAKDAYRDYLELHGLSVQLTEALAEYWHARVRAEWGIG
GDETLDDMLKVNIQGCRYSFGYPACPNLEDQVQLFQLLQPERIGVSLSEEFQLHPEQATS
ALVAHHPEAKYFNV
NT seq
3465 nt
NT seq
+upstream
nt +downstream
nt
atgagcatctccccgtccttccgtgaagtgcttgaccagcgcgtgatcgtcgccgacggc
gccatgggcacgatgctccaggcccaggacccgacgctcgacgacttccacggccacgag
ggctgcaacgaggtgctcaacgtctcgcgccccgacatcgtgcgaggcgtccacgacgcc
tacttcgccgtcggcgtcgactgcgtcgagaccaacaccttcggcgccaacctcgccgcg
ctcggcgaatacgacatcgccgaccgcgtcttcgaatactccgaggccggcgcccgcatc
gcccgcgaggcggccgaccactggtccacgcccgagcagccgcgcttcgtcctcggctcg
atgggccccggcaccaagctgcccacgctcggccacctgccctacgcgagcctccgcgac
gcctaccgcgacaacgccgccggcctcatcgcgggcggcgccgacgccctcatcgtcgag
acctgccaggacctcctccaggtcaaggccgccgtcatcggcgccaagcgggccgccgag
gactccggccgcgacatcccgatcatcgcccaggtcaccatcgagaccaacggcgcgatg
ctgctgggcagcgagatcggcgcggcgctgaccgccatcgagccgctcggcgtcgacgtc
atcgggctcaactgcgccaccggccccgccgagatgagcgagcacctgcgccacctcgcc
cgccactcccggctccggctgagctgcatgcccaacgcgggcctgccggtgctcacctcc
gacggcgcctactacccgctcagccccggcgagctggccgacgcccacggcgccttcacc
cgcgactacgggctgtccctggtcggcggctgctgcggcaccacccccgagcacctgcgc
caggtcgtcgagcgggtgcgcggcaaggagaccgcgccgcgccgcccccgccccgagccg
ggcgtctcctcgctctaccagagcgtcccgttccgccaggacacctccttcctcgccatc
ggcgagcgctgcaacaccaacggctccaaggcattccgcgaggcgatgctgggcgggcgc
tgggacgactgcgtcgagatggcccgcgagcaggcccgcggcggcgcccacatgctcgac
ctctgcgtcgactacgtcggccgcgacggcgtcgccgacatgaaggagctggccttccgc
ttcgccaccgcctccaccctgccgatcatgctcgactccaccgagcccgaggtgctgcgc
gcgggcctggagatgctgggcggccgggcggcggtcaactccgtcaactacgaggacggc
gccggccccgactcccgcttccagaagatcatgcgtctggtgcgcgagcacggcgccgcc
gtggtcgccctcaccatcgacgaggagggccaggcccgcaccgccgactggaaggtgcgc
gtcgcgagccgcctgatcgaggacctgaccaccaactggggcatgcaggtcgaggacatc
atcgtcgacaccctcaccttccccatcgccaccggccaggaggagacccgccgcgacggc
ctggagaccatcgaggccatccgcgagctcaagcgccgctacccgggcgtgcagaccacg
ctcggcgtctccaacatcagcttcggcctcaacccggccgcccgcatggtgctcaactcg
gtcttcctcaacgagtgcgtcaacgccgggctcgactccgcgatcgtgcacgcctcgaag
atcctgccgatggcgcgcatccccgacgagcagcgccaggtcgccctcgacatggtctac
gaccgccgccgcgagggctacgacccgctgcagcgcttcatggacctgttcgagggcgtc
gacgccgccgcgctgcgcgccggcaaggccgaggagctggcctcgctgccgctgtgggag
cggctcaagcggcgcatcgtggacggtgagcgcaagggcctggaggccgacctcgacacc
gcgctggagcagcgccccgcgctggagatcatcaacgaggtgctgctcgacggcatgaag
accgtcggcgtgctgttcggctccgggcagatgcagctgccgttcgtgctgcagtcggcc
gaggtcatgaaggccgcggtcgcccacctcgagccccacatggagcgcgtggagggcgag
accaagggccgcatcgtgctggccaccgtcaagggcgacgtccacgacatcggcaagaac
ctcgtcgacatcatcctgtccaacaacggctaccaggtcgtcaacctcggcatcaagcag
ccggtctcggccatcctcgaggccgccgacgagcagaaggccgacgtgatcggcatgtcc
gggctgctggtcaagtcgaccgtggtgatgaaggagaacctggaggagatgaactccagg
ggcctgtcggaccgatacccggtgctgctcggcggcgccgcgctcacccgcgcctacgtc
gagcaggacctcgccgagctgttcgagggcgaggtgcgctacgcccgcgacgccttcgag
gggctgcggctcatggacgcgttcatggccgtcaagcgtggcgagaagggcgcgacgctg
ccgccgctgcgcgagcggcgggtcaagaccggcgcggtgctccagcgcaccccggtcgag
gagctgcctgcccgctccgacgtcgccgccgacaacccggtcccggtggccccgttcctc
ggcgaccgcgtcgtcaagggcgtctcgctggccgactacgcggccttcctcgacgagcgc
gcgctgttcctcggccagtgggggctcaagcccaccaggggcggcgaaggtcccggctac
gacgagctggtcgagaccgagggccggccccggctgcgcatgtggctcgaccgcatccag
accgagggcctgctggaggcggccgtcgtctacgggcacttcccgtgcgtcagcgacggc
gactcgctcgtcatcctcgacgacgcgggcggcgagcgcacccgcttcaccttcccgcgc
cagcgccgcgaccgccacctgtgcctgtccgacttcttccgcccgaaggagtccggcgag
gtcgacgtggtcggcttccaggtcgtcaccatgggcgcgaagatcgcgcaggccacggcc
gagctgttcgccaaggacgcctaccgcgactacctcgaactgcacggcctgtcggtgcag
ctcaccgaggcgctggccgaatactggcacgcccgggtgcgcgccgagtggggcatcggc
ggagacgagacgctcgacgacatgctcaaggtcaacatccagggctgccgctactccttc
ggctacccggcgtgccccaacctggaggaccaggtgcagctcttccagctcctccagccc
gagcgcatcggggtgagcctgtcggaggagttccagctccacccggagcaggccacgtcc
gcgctggtggcgcaccaccccgaggccaaatacttcaacgtctga
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