Nonomuraea coxensis: Nocox_30970
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Entry
Nocox_30970 CDS
T07466
Symbol
aceE
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ncx
Nonomuraea coxensis
Pathway
ncx00010
Glycolysis / Gluconeogenesis
ncx00020
Citrate cycle (TCA cycle)
ncx00620
Pyruvate metabolism
ncx00785
Lipoic acid metabolism
ncx01100
Metabolic pathways
ncx01110
Biosynthesis of secondary metabolites
ncx01120
Microbial metabolism in diverse environments
ncx01200
Carbon metabolism
ncx01210
2-Oxocarboxylic acid metabolism
Module
ncx_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ncx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Nocox_30970 (aceE)
00020 Citrate cycle (TCA cycle)
Nocox_30970 (aceE)
00620 Pyruvate metabolism
Nocox_30970 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Nocox_30970 (aceE)
Enzymes [BR:
ncx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Nocox_30970 (aceE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transket_pyr
Radical_SAM
Motif
Other DBs
NCBI-ProteinID:
QYC43775
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Position
6621424..6624222
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AA seq
932 aa
AA seq
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MEDDQTQTSVILGRRDPVASGRQRFSIISDGLPSQLPDVDPSETNEWLESLDNVVKTEGR
TRARYLMLRMLERAREHQVGVPGLRSTDYINTIPPEREPWFPGDEHVERRIRAYIRWNAA
VMVSRANARTNVGGHIATYASAASLYEVGFNHFFRGKDHGESGDQVFFQGHAAPGIYARA
FLEGRLNESQLDAFRQELSHGFHGLPSYPHPRLMPDFWEFPTVSMGLGPIGAIYQARFNR
YLLNRQIKDTSRSHVWAFLGDGEMDEPESLGAIGVAAREELDNLTFVINCNLQRLDGPVR
GNGKIIQELESYFRGAGWNVIKVVWGRDWDPLLAADVDGVLVNQMNTTPDGQFQTYSVES
GAYIREHFFGSDPRLRKMVEHLSDDDIRKLSRGGHDYRKVYAAFKAAREHVGQPTVILAQ
TIKGWTLGKDFEARNATHQMKKLTKAELKEFRDRLYLPIPDSALEGDLPPYFHPGENDAE
IQYMKERRAALGGVLPKRVQRAKPIKLPGDEVYKSFGKGSGKQQVATTMAFVRLLKDLMR
DKEIGHRFVPIIPDEARTFGMDAMFPSAKIYSPHGQTYEAVDRELLLSYKEAVQGQILHE
GISESGSMASAIAAGTSYATHGEHMIPIYIFYSMFGWQRTGDQMWQMGDQMTRGFLLGAT
AGRTTLNGEGLQHEDGHTPLIASTNPAAISYDPSWAFEVAHIVKDGLRRMYGDQPEDVFY
YLTVYNEPYLQPAEPANLDVQALLKGLYKFAEGPRTEGPKANILSSGVAGPWAMEAQRLL
AEDWGVSADVWSATSWSELRREALACEEHNLLNPEAEQRVPYVTQALSGAQGPFVGVSDY
MKAVQDQIAQWVPGDWSSLGTDGFGLSDTRSALRRHFHVDAASITLAVLTQLVRRKELDG
EVLREAIARYHLKNGVTEAGGAESNDTQSMGV
NT seq
2799 nt
NT seq
+upstream
nt +downstream
nt
atggaagacgaccagacccagacatcagtcattctcggaaggcgagacccagtggcttcc
ggacgccagcgattctcgatcatcagcgacggcctacccagccagctgcctgatgtcgat
cccagtgagaccaacgagtggctcgagtctctcgacaacgtcgtcaagaccgaaggccgc
accagagcccgctacctgatgctgcgcatgctggagcgggcccgcgagcaccaggtcggc
gtgccgggcctgcggagcaccgactacatcaacaccatcccgccggagcgcgagccctgg
ttcccgggtgacgagcacgtcgagcgccgcatccgtgcctacatccgctggaacgcggcg
gtcatggtgtcccgggccaacgcccgcaccaacgtcggcggtcacatcgcgacctacgcc
tccgccgcgtcgctctacgaggtgggcttcaaccacttcttccgcggcaaggaccacggc
gagtcgggcgaccaggtcttcttccagggccacgccgcgccgggcatctacgcccgcgcc
ttcctggagggccggctcaacgagtcgcagctcgacgcgttccgccaggagctgtcgcac
ggcttccacggcctgccctcctacccgcacccgcggctcatgcccgacttctgggagttc
ccgaccgtctccatgggcctcggcccgatcggcgcgatctaccaggcgcggttcaaccgc
tacctgctcaaccgccagatcaaggacaccagccgcagccacgtgtgggccttcctcggc
gacggcgagatggacgagcccgagtcgctcggcgccatcggcgtggccgcccgcgaggag
ctggacaacctcacgttcgtcatcaactgcaacctgcagcggctcgacggccccgtacgc
ggcaacggcaagatcatccaggagctggagtcctacttccgcggcgccggctggaacgtc
atcaaggtcgtctggggccgcgactgggacccgctgctcgccgccgacgtcgacggcgtg
ctggtcaaccagatgaacaccacgcccgacggccagttccagacctactcggtcgagtcg
ggcgcctacatccgcgagcacttcttcggctccgacccgcgcctgcgcaagatggtcgag
cacctgtccgacgacgacatccgcaagctgtcgcgcggcggccacgactaccgcaaggtc
tacgcggccttcaaggcggcccgcgagcacgtcggccagccgaccgtgatcctcgcccag
accatcaagggctggaccctcggcaaggacttcgaggcgcgcaacgccacgcaccagatg
aagaagctcaccaaggccgagctcaaggagttcagggaccggctctacctgccgatcccc
gactcggcgctggaaggcgacctgccgccctacttccacccgggcgagaacgacgccgag
atccagtacatgaaggagcgccgggccgcgctcggcggcgtgctgccgaagcgcgtccag
cgggccaagccgatcaagctgccgggcgacgaggtctacaagtccttcggcaagggctcc
ggcaagcagcaggtggccaccaccatggcgttcgtccgcctgctcaaggacctcatgcgc
gacaaggagatcggccaccggttcgtgccgatcatccccgacgaggcgcgcacgttcggc
atggacgccatgttcccgtcggcgaagatctactcgccgcacggccagacgtacgaggcc
gtcgaccgggagctgctgctgtcgtacaaggaggccgtgcagggccagatcctgcacgag
ggcatcagcgagtcgggctcgatggcctcggcgatcgccgccggcacctcctacgccacg
cacggcgagcacatgatcccgatctacatcttctactcgatgttcgggtggcagcgcacc
ggcgaccagatgtggcagatgggcgaccagatgacccgcggcttcctgctgggcgccacg
gccggccgcaccacgctcaacggcgagggcctgcagcacgaggacggccacacgccgctc
atcgcctccaccaaccccgccgcgatctcctacgacccgtcatgggcgttcgaggtggcc
cacatcgtcaaggacggcctgcggcgcatgtacggcgaccagccggaggacgtcttctac
tacctgaccgtctacaacgagccctacctgcagcccgccgagccggcgaacctcgacgtg
caggccctgctcaagggtctctacaagttcgccgaggggccgcggacggagggcccgaag
gccaacatcctgtcctcgggcgtggccggcccgtgggcgatggaggcgcagcgcctgctc
gccgaggactggggcgtctccgccgacgtgtggtcggccacgtcctggtcggagctgcgc
cgcgaggcgctggcctgcgaggagcacaacctgctcaacccggaggccgagcagcgcgtc
ccctacgtcacccaggcgctgtccggcgcccaggggccgttcgtgggggtcagcgactac
atgaaggccgtccaggaccagatcgcgcagtgggtgccgggtgactggtcctcgctgggc
accgacgggttcggcctgtccgacacgcgctcggcgctgcgccgccacttccacgtggac
gcggcctcgatcacgctggcggtgctgacccagctcgtacgccgcaaggagctcgacggc
gaggtgctgcgcgaggccatcgcccgctaccacctcaagaacggcgtcaccgaggccggc
ggcgcggagagcaacgacacccagtcgatgggcgtctga
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