KEGG   NETWORK: N01019
Entry
N01019                      Network                                
Name
Parkin-mediated ubiquitination
Definition
UBCH7/8 == PRKN -| alphaSp22
  Expanded
(7332,9246) == 5071 -| 6622
Class
nt06463 Parkinson disease
nt06466 Pathways of neurodegeneration
Type
Reference
Pathway
hsa04120  Ubiquitin mediated proteolysis
Gene
7332  UBE2L3; ubiquitin conjugating enzyme E2 L3
9246  UBE2L6; ubiquitin conjugating enzyme E2 L6
5071  PRKN; parkin RBR E3 ubiquitin protein ligase
6622  SNCA; synuclein alpha
Reference
  Authors
Hattori N, Mizuno Y
  Title
Twenty years since the discovery of the parkin gene.
  Journal
J Neural Transm (Vienna) 124:1037-1054 (2017)
DOI:10.1007/s00702-017-1742-7
Reference
  Authors
Dev KK, van der Putten H, Sommer B, Rovelli G
  Title
Part I: parkin-associated proteins and Parkinson's disease.
  Journal
Neuropharmacology 45:1-13 (2003)
DOI:10.1016/s0028-3908(02)00337-4
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