Nannospalax galili (Upper Galilee mountains blind mole rat): 103726879
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Entry
103726879 CDS
T03372
Symbol
Pik3r2
Name
(RefSeq) phosphoinositide-3-kinase regulatory subunit 2
KO
K02649
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01521
EGFR tyrosine kinase inhibitor resistance
ngi01522
Endocrine resistance
ngi01524
Platinum drug resistance
ngi04012
ErbB signaling pathway
ngi04014
Ras signaling pathway
ngi04015
Rap1 signaling pathway
ngi04024
cAMP signaling pathway
ngi04062
Chemokine signaling pathway
ngi04066
HIF-1 signaling pathway
ngi04068
FoxO signaling pathway
ngi04070
Phosphatidylinositol signaling system
ngi04071
Sphingolipid signaling pathway
ngi04072
Phospholipase D signaling pathway
ngi04081
Hormone signaling
ngi04140
Autophagy - animal
ngi04145
Phagocytosis
ngi04150
mTOR signaling pathway
ngi04151
PI3K-Akt signaling pathway
ngi04152
AMPK signaling pathway
ngi04210
Apoptosis
ngi04211
Longevity regulating pathway
ngi04213
Longevity regulating pathway - multiple species
ngi04218
Cellular senescence
ngi04360
Axon guidance
ngi04370
VEGF signaling pathway
ngi04380
Osteoclast differentiation
ngi04510
Focal adhesion
ngi04517
IgSF CAM signaling
ngi04518
Integrin signaling
ngi04550
Signaling pathways regulating pluripotency of stem cells
ngi04611
Platelet activation
ngi04613
Neutrophil extracellular trap formation
ngi04620
Toll-like receptor signaling pathway
ngi04625
C-type lectin receptor signaling pathway
ngi04630
JAK-STAT signaling pathway
ngi04650
Natural killer cell mediated cytotoxicity
ngi04660
T cell receptor signaling pathway
ngi04662
B cell receptor signaling pathway
ngi04664
Fc epsilon RI signaling pathway
ngi04666
Fc gamma R-mediated phagosome formation
ngi04668
TNF signaling pathway
ngi04670
Leukocyte transendothelial migration
ngi04722
Neurotrophin signaling pathway
ngi04725
Cholinergic synapse
ngi04750
Inflammatory mediator regulation of TRP channels
ngi04810
Regulation of actin cytoskeleton
ngi04910
Insulin signaling pathway
ngi04914
Progesterone-mediated oocyte maturation
ngi04915
Estrogen signaling pathway
ngi04917
Prolactin signaling pathway
ngi04919
Thyroid hormone signaling pathway
ngi04923
Regulation of lipolysis in adipocytes
ngi04926
Relaxin signaling pathway
ngi04929
GnRH secretion
ngi04930
Type II diabetes mellitus
ngi04931
Insulin resistance
ngi04932
Non-alcoholic fatty liver disease
ngi04933
AGE-RAGE signaling pathway in diabetic complications
ngi04935
Growth hormone synthesis, secretion and action
ngi04960
Aldosterone-regulated sodium reabsorption
ngi04973
Carbohydrate digestion and absorption
ngi05010
Alzheimer disease
ngi05017
Spinocerebellar ataxia
ngi05020
Prion disease
ngi05100
Bacterial invasion of epithelial cells
ngi05135
Yersinia infection
ngi05142
Chagas disease
ngi05146
Amoebiasis
ngi05160
Hepatitis C
ngi05161
Hepatitis B
ngi05162
Measles
ngi05163
Human cytomegalovirus infection
ngi05164
Influenza A
ngi05165
Human papillomavirus infection
ngi05166
Human T-cell leukemia virus 1 infection
ngi05167
Kaposi sarcoma-associated herpesvirus infection
ngi05168
Herpes simplex virus 1 infection
ngi05169
Epstein-Barr virus infection
ngi05170
Human immunodeficiency virus 1 infection
ngi05171
Coronavirus disease
ngi05200
Pathways in cancer
ngi05203
Viral carcinogenesis
ngi05205
Proteoglycans in cancer
ngi05206
MicroRNAs in cancer
ngi05207
Chemical carcinogenesis - receptor activation
ngi05208
Chemical carcinogenesis - reactive oxygen species
ngi05210
Colorectal cancer
ngi05211
Renal cell carcinoma
ngi05212
Pancreatic cancer
ngi05213
Endometrial cancer
ngi05214
Glioma
ngi05215
Prostate cancer
ngi05218
Melanoma
ngi05220
Chronic myeloid leukemia
ngi05221
Acute myeloid leukemia
ngi05222
Small cell lung cancer
ngi05223
Non-small cell lung cancer
ngi05224
Breast cancer
ngi05225
Hepatocellular carcinoma
ngi05226
Gastric cancer
ngi05230
Central carbon metabolism in cancer
ngi05231
Choline metabolism in cancer
ngi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ngi05415
Diabetic cardiomyopathy
ngi05417
Lipid and atherosclerosis
ngi05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
103726879 (Pik3r2)
04014 Ras signaling pathway
103726879 (Pik3r2)
04015 Rap1 signaling pathway
103726879 (Pik3r2)
04370 VEGF signaling pathway
103726879 (Pik3r2)
04630 JAK-STAT signaling pathway
103726879 (Pik3r2)
04668 TNF signaling pathway
103726879 (Pik3r2)
04066 HIF-1 signaling pathway
103726879 (Pik3r2)
04068 FoxO signaling pathway
103726879 (Pik3r2)
04070 Phosphatidylinositol signaling system
103726879 (Pik3r2)
04072 Phospholipase D signaling pathway
103726879 (Pik3r2)
04071 Sphingolipid signaling pathway
103726879 (Pik3r2)
04024 cAMP signaling pathway
103726879 (Pik3r2)
04151 PI3K-Akt signaling pathway
103726879 (Pik3r2)
04152 AMPK signaling pathway
103726879 (Pik3r2)
04150 mTOR signaling pathway
103726879 (Pik3r2)
09133 Signaling molecules and interaction
04081 Hormone signaling
103726879 (Pik3r2)
04517 IgSF CAM signaling
103726879 (Pik3r2)
04518 Integrin signaling
103726879 (Pik3r2)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagocytosis
103726879 (Pik3r2)
04140 Autophagy - animal
103726879 (Pik3r2)
09143 Cell growth and death
04210 Apoptosis
103726879 (Pik3r2)
04218 Cellular senescence
103726879 (Pik3r2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103726879 (Pik3r2)
04550 Signaling pathways regulating pluripotency of stem cells
103726879 (Pik3r2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103726879 (Pik3r2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103726879 (Pik3r2)
04613 Neutrophil extracellular trap formation
103726879 (Pik3r2)
04620 Toll-like receptor signaling pathway
103726879 (Pik3r2)
04625 C-type lectin receptor signaling pathway
103726879 (Pik3r2)
04650 Natural killer cell mediated cytotoxicity
103726879 (Pik3r2)
04660 T cell receptor signaling pathway
103726879 (Pik3r2)
04662 B cell receptor signaling pathway
103726879 (Pik3r2)
04664 Fc epsilon RI signaling pathway
103726879 (Pik3r2)
04666 Fc gamma R-mediated phagosome formation
103726879 (Pik3r2)
04670 Leukocyte transendothelial migration
103726879 (Pik3r2)
04062 Chemokine signaling pathway
103726879 (Pik3r2)
09152 Endocrine system
04910 Insulin signaling pathway
103726879 (Pik3r2)
04923 Regulation of lipolysis in adipocytes
103726879 (Pik3r2)
04929 GnRH secretion
103726879 (Pik3r2)
04915 Estrogen signaling pathway
103726879 (Pik3r2)
04914 Progesterone-mediated oocyte maturation
103726879 (Pik3r2)
04917 Prolactin signaling pathway
103726879 (Pik3r2)
04926 Relaxin signaling pathway
103726879 (Pik3r2)
04935 Growth hormone synthesis, secretion and action
103726879 (Pik3r2)
04919 Thyroid hormone signaling pathway
103726879 (Pik3r2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
103726879 (Pik3r2)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
103726879 (Pik3r2)
09156 Nervous system
04725 Cholinergic synapse
103726879 (Pik3r2)
04722 Neurotrophin signaling pathway
103726879 (Pik3r2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
103726879 (Pik3r2)
09158 Development and regeneration
04360 Axon guidance
103726879 (Pik3r2)
04380 Osteoclast differentiation
103726879 (Pik3r2)
09149 Aging
04211 Longevity regulating pathway
103726879 (Pik3r2)
04213 Longevity regulating pathway - multiple species
103726879 (Pik3r2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103726879 (Pik3r2)
05206 MicroRNAs in cancer
103726879 (Pik3r2)
05205 Proteoglycans in cancer
103726879 (Pik3r2)
05207 Chemical carcinogenesis - receptor activation
103726879 (Pik3r2)
05208 Chemical carcinogenesis - reactive oxygen species
103726879 (Pik3r2)
05203 Viral carcinogenesis
103726879 (Pik3r2)
05230 Central carbon metabolism in cancer
103726879 (Pik3r2)
05231 Choline metabolism in cancer
103726879 (Pik3r2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103726879 (Pik3r2)
09162 Cancer: specific types
05210 Colorectal cancer
103726879 (Pik3r2)
05212 Pancreatic cancer
103726879 (Pik3r2)
05225 Hepatocellular carcinoma
103726879 (Pik3r2)
05226 Gastric cancer
103726879 (Pik3r2)
05214 Glioma
103726879 (Pik3r2)
05221 Acute myeloid leukemia
103726879 (Pik3r2)
05220 Chronic myeloid leukemia
103726879 (Pik3r2)
05218 Melanoma
103726879 (Pik3r2)
05211 Renal cell carcinoma
103726879 (Pik3r2)
05215 Prostate cancer
103726879 (Pik3r2)
05213 Endometrial cancer
103726879 (Pik3r2)
05224 Breast cancer
103726879 (Pik3r2)
05222 Small cell lung cancer
103726879 (Pik3r2)
05223 Non-small cell lung cancer
103726879 (Pik3r2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103726879 (Pik3r2)
05170 Human immunodeficiency virus 1 infection
103726879 (Pik3r2)
05161 Hepatitis B
103726879 (Pik3r2)
05160 Hepatitis C
103726879 (Pik3r2)
05171 Coronavirus disease
103726879 (Pik3r2)
05164 Influenza A
103726879 (Pik3r2)
05162 Measles
103726879 (Pik3r2)
05168 Herpes simplex virus 1 infection
103726879 (Pik3r2)
05163 Human cytomegalovirus infection
103726879 (Pik3r2)
05167 Kaposi sarcoma-associated herpesvirus infection
103726879 (Pik3r2)
05169 Epstein-Barr virus infection
103726879 (Pik3r2)
05165 Human papillomavirus infection
103726879 (Pik3r2)
09171 Infectious disease: bacterial
05135 Yersinia infection
103726879 (Pik3r2)
05100 Bacterial invasion of epithelial cells
103726879 (Pik3r2)
09174 Infectious disease: parasitic
05146 Amoebiasis
103726879 (Pik3r2)
05142 Chagas disease
103726879 (Pik3r2)
09164 Neurodegenerative disease
05010 Alzheimer disease
103726879 (Pik3r2)
05017 Spinocerebellar ataxia
103726879 (Pik3r2)
05020 Prion disease
103726879 (Pik3r2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103726879 (Pik3r2)
05418 Fluid shear stress and atherosclerosis
103726879 (Pik3r2)
05415 Diabetic cardiomyopathy
103726879 (Pik3r2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103726879 (Pik3r2)
04932 Non-alcoholic fatty liver disease
103726879 (Pik3r2)
04931 Insulin resistance
103726879 (Pik3r2)
04933 AGE-RAGE signaling pathway in diabetic complications
103726879 (Pik3r2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103726879 (Pik3r2)
01524 Platinum drug resistance
103726879 (Pik3r2)
01522 Endocrine resistance
103726879 (Pik3r2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ngi04131
]
103726879 (Pik3r2)
Membrane trafficking [BR:
ngi04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
103726879 (Pik3r2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3K_P85_iSH2
SH2
RhoGAP
SH2_1
SH3_1
SH3_9
Ribosomal_L22e
ODF2_C
ATG11
Motif
Other DBs
NCBI-GeneID:
103726879
NCBI-ProteinID:
XP_008822787
LinkDB
All DBs
Position
Un
AA seq
722 aa
AA seq
DB search
MAMAGAEGFQYRALYPFRRERPDDLELLPGDLLVVSRAALQALGVADGGERCPHNVGWMP
GFNERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPLDGSSESGLILPDLREQF
SPPDPAPPILVKLAEAIEQTGLDSECYYRPELPVPRTDWSLSDVEHWEPVALADAVKGFL
LALPTALVTPEAVAEAHRALREAAGPVGLVLEPPTLPLHPALTLRFLLQHLGRLVRRAPA
PGPAVHALALAFGPLLLRALPPGAAEGSEPNPDFPELLVEKLLQEHVDEQEAAPPALPPK
PSKAKPTPTGLANGGSPLSLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIHGEY
TLTLRKGGNNKLIKVFHRDGHYGFSEPLTFGSVVELISHYRHESLAQYNAKLDTRLLYPV
SKYQQDQVVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFN
ETIKIFEEQGQTQEKCSRQYLDRFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQD
LRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNETEDQY
SLMEEEDDLPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDT
KHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPA
AR
NT seq
2169 nt
NT seq
+upstream
nt +downstream
nt
atggccatggccggagcagagggcttccagtaccgggctctgtacccattccgccgggag
cggcctgacgacctggagctactgccgggagacttgctggtggtgagccgtgcagcccta
caggcgctgggcgtggcagatggtggggagcgttgcccgcacaacgtgggctggatgccc
ggcttcaatgagcgcacccggcagcggggggacttccccgggacatatgtggagttcctg
gggcctgtggctctggctcgaccaggcccaaggccccgaggcccccgtccactgcctgct
agacccctggatgggtcctccgagtcaggcctcatactcccagaccttcgggaacagttc
tctcctcctgacccagcaccccccatcctggtgaagctggcagaggccattgagcaaaca
gggctggacagtgagtgctactacaggccagaactgcctgtgcccaggacagactggtcc
ctgagtgatgtggagcactgggagcctgtggccttggcagacgctgtgaagggcttcctg
ctggccttacctacggccctggtgacccctgaggctgtggcggaggcacatcgggcactg
cgggaagctgctgggcccgtgggactggtgctggaacccccaacgctgccgctgcacccg
gcactgacgctgcggttcctgctgcagcacctgggccgcctggtgcggagagcgcccgcc
cctgggcctgctgttcatgcactggctctagccttcgggcctctgctactgcgcgccctg
ccaccaggggccgctgaggggagtgagccgaaccctgacttccctgaactgctggtggag
aaactgctacaagagcacgtggatgaacaggaggccgcgcccccagcactgccacctaag
ccctctaaggcaaagccaacgcccacaggcctggccaatggagggagcccgctgtctcta
caggatgcggagtggtactggggggacatctccagggaagaagtcaatgagaagctccgg
gacacacccgatggcaccttcctggtccgagacgcatccagtaagatccatggagagtac
acactcacactcaggaaaggtggtaacaataaattgattaaggtcttccaccgtgatgga
cactacggcttctcggagcccctcaccttcggctcggtggtagagctgatctcccactat
cgccatgagtcactggcacagtataacgccaagctggacactcgcctcctctaccccgtg
tccaagtaccagcaggaccaggtggtgaaagaggacagcgtggaggcagtgggggcccag
ctcaaagtgtaccaccagcagtaccaggacaagagccgagagtacgaccagctgtacgag
gagtacacgcgtacctcccaggaactgcagatgaagcgcacagccatcgaagccttcaat
gaaaccatcaagatctttgaagaacaaggccagacacaggagaagtgcagcaggcagtat
ctggaccgcttccgacgggagggcaatgagaaggagatgcagaggatccttctgaactct
gaacggctcaagtcgcgaattgcggagatacatgagagtcgcacaaaactggagcaagac
ctgcgggcacaggcctcagacaaccgtgagatcgacaagcgcatgaacagcctcaagcct
gatctcatgcaactgcgcaagatcagagaccagtaccttgtgtggctcacccagaagggc
gcccggcagaagaaaatcaatgagtggctgggaatcaaaaatgagacagaggaccagtat
tccctgatggaggaggaggatgacctccctcaccacgaggaacgcacatggtacgtgggc
aagatcaaccgcacccaggcggaagagatgctgagcgggaagcgtgacgggacgttcctc
atccgtgagagcagccagcggggctgctatgcctgctccgtggtggtggacggtgacacc
aagcattgtgtcatctaccgcacagccaccggttttggctttgcagagccttacaacctg
tatggatcgctgaaggagctggtgctgcactaccagcacgcatccctcgtgcaacacaac
gatgctctcacggtcacccttgcccaccctgtacgtgccccagggccagggcccccagct
gcccgctga
DBGET
integrated database retrieval system
