Nannospalax galili (Upper Galilee mountains blind mole rat): 103738715
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Entry
103738715 CDS
T03372
Symbol
Pik3r1
Name
(RefSeq) phosphoinositide-3-kinase regulatory subunit 1
KO
K02649
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01521
EGFR tyrosine kinase inhibitor resistance
ngi01522
Endocrine resistance
ngi01524
Platinum drug resistance
ngi04012
ErbB signaling pathway
ngi04014
Ras signaling pathway
ngi04015
Rap1 signaling pathway
ngi04024
cAMP signaling pathway
ngi04062
Chemokine signaling pathway
ngi04066
HIF-1 signaling pathway
ngi04068
FoxO signaling pathway
ngi04070
Phosphatidylinositol signaling system
ngi04071
Sphingolipid signaling pathway
ngi04072
Phospholipase D signaling pathway
ngi04081
Hormone signaling
ngi04140
Autophagy - animal
ngi04150
mTOR signaling pathway
ngi04151
PI3K-Akt signaling pathway
ngi04152
AMPK signaling pathway
ngi04210
Apoptosis
ngi04211
Longevity regulating pathway
ngi04213
Longevity regulating pathway - multiple species
ngi04218
Cellular senescence
ngi04360
Axon guidance
ngi04370
VEGF signaling pathway
ngi04380
Osteoclast differentiation
ngi04510
Focal adhesion
ngi04550
Signaling pathways regulating pluripotency of stem cells
ngi04611
Platelet activation
ngi04613
Neutrophil extracellular trap formation
ngi04620
Toll-like receptor signaling pathway
ngi04625
C-type lectin receptor signaling pathway
ngi04630
JAK-STAT signaling pathway
ngi04650
Natural killer cell mediated cytotoxicity
ngi04660
T cell receptor signaling pathway
ngi04662
B cell receptor signaling pathway
ngi04664
Fc epsilon RI signaling pathway
ngi04666
Fc gamma R-mediated phagocytosis
ngi04668
TNF signaling pathway
ngi04670
Leukocyte transendothelial migration
ngi04722
Neurotrophin signaling pathway
ngi04725
Cholinergic synapse
ngi04750
Inflammatory mediator regulation of TRP channels
ngi04810
Regulation of actin cytoskeleton
ngi04910
Insulin signaling pathway
ngi04914
Progesterone-mediated oocyte maturation
ngi04915
Estrogen signaling pathway
ngi04917
Prolactin signaling pathway
ngi04919
Thyroid hormone signaling pathway
ngi04923
Regulation of lipolysis in adipocytes
ngi04926
Relaxin signaling pathway
ngi04929
GnRH secretion
ngi04930
Type II diabetes mellitus
ngi04931
Insulin resistance
ngi04932
Non-alcoholic fatty liver disease
ngi04933
AGE-RAGE signaling pathway in diabetic complications
ngi04935
Growth hormone synthesis, secretion and action
ngi04960
Aldosterone-regulated sodium reabsorption
ngi04973
Carbohydrate digestion and absorption
ngi05010
Alzheimer disease
ngi05017
Spinocerebellar ataxia
ngi05020
Prion disease
ngi05100
Bacterial invasion of epithelial cells
ngi05135
Yersinia infection
ngi05142
Chagas disease
ngi05146
Amoebiasis
ngi05160
Hepatitis C
ngi05161
Hepatitis B
ngi05162
Measles
ngi05163
Human cytomegalovirus infection
ngi05164
Influenza A
ngi05165
Human papillomavirus infection
ngi05166
Human T-cell leukemia virus 1 infection
ngi05167
Kaposi sarcoma-associated herpesvirus infection
ngi05168
Herpes simplex virus 1 infection
ngi05169
Epstein-Barr virus infection
ngi05170
Human immunodeficiency virus 1 infection
ngi05171
Coronavirus disease - COVID-19
ngi05200
Pathways in cancer
ngi05203
Viral carcinogenesis
ngi05205
Proteoglycans in cancer
ngi05206
MicroRNAs in cancer
ngi05207
Chemical carcinogenesis - receptor activation
ngi05208
Chemical carcinogenesis - reactive oxygen species
ngi05210
Colorectal cancer
ngi05211
Renal cell carcinoma
ngi05212
Pancreatic cancer
ngi05213
Endometrial cancer
ngi05214
Glioma
ngi05215
Prostate cancer
ngi05218
Melanoma
ngi05220
Chronic myeloid leukemia
ngi05221
Acute myeloid leukemia
ngi05222
Small cell lung cancer
ngi05223
Non-small cell lung cancer
ngi05224
Breast cancer
ngi05225
Hepatocellular carcinoma
ngi05226
Gastric cancer
ngi05230
Central carbon metabolism in cancer
ngi05231
Choline metabolism in cancer
ngi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ngi05415
Diabetic cardiomyopathy
ngi05417
Lipid and atherosclerosis
ngi05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
103738715 (Pik3r1)
04014 Ras signaling pathway
103738715 (Pik3r1)
04015 Rap1 signaling pathway
103738715 (Pik3r1)
04370 VEGF signaling pathway
103738715 (Pik3r1)
04630 JAK-STAT signaling pathway
103738715 (Pik3r1)
04668 TNF signaling pathway
103738715 (Pik3r1)
04066 HIF-1 signaling pathway
103738715 (Pik3r1)
04068 FoxO signaling pathway
103738715 (Pik3r1)
04070 Phosphatidylinositol signaling system
103738715 (Pik3r1)
04072 Phospholipase D signaling pathway
103738715 (Pik3r1)
04071 Sphingolipid signaling pathway
103738715 (Pik3r1)
04024 cAMP signaling pathway
103738715 (Pik3r1)
04151 PI3K-Akt signaling pathway
103738715 (Pik3r1)
04152 AMPK signaling pathway
103738715 (Pik3r1)
04150 mTOR signaling pathway
103738715 (Pik3r1)
09133 Signaling molecules and interaction
04081 Hormone signaling
103738715 (Pik3r1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103738715 (Pik3r1)
09143 Cell growth and death
04210 Apoptosis
103738715 (Pik3r1)
04218 Cellular senescence
103738715 (Pik3r1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103738715 (Pik3r1)
04550 Signaling pathways regulating pluripotency of stem cells
103738715 (Pik3r1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103738715 (Pik3r1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103738715 (Pik3r1)
04613 Neutrophil extracellular trap formation
103738715 (Pik3r1)
04620 Toll-like receptor signaling pathway
103738715 (Pik3r1)
04625 C-type lectin receptor signaling pathway
103738715 (Pik3r1)
04650 Natural killer cell mediated cytotoxicity
103738715 (Pik3r1)
04660 T cell receptor signaling pathway
103738715 (Pik3r1)
04662 B cell receptor signaling pathway
103738715 (Pik3r1)
04664 Fc epsilon RI signaling pathway
103738715 (Pik3r1)
04666 Fc gamma R-mediated phagocytosis
103738715 (Pik3r1)
04670 Leukocyte transendothelial migration
103738715 (Pik3r1)
04062 Chemokine signaling pathway
103738715 (Pik3r1)
09152 Endocrine system
04910 Insulin signaling pathway
103738715 (Pik3r1)
04923 Regulation of lipolysis in adipocytes
103738715 (Pik3r1)
04929 GnRH secretion
103738715 (Pik3r1)
04915 Estrogen signaling pathway
103738715 (Pik3r1)
04914 Progesterone-mediated oocyte maturation
103738715 (Pik3r1)
04917 Prolactin signaling pathway
103738715 (Pik3r1)
04926 Relaxin signaling pathway
103738715 (Pik3r1)
04935 Growth hormone synthesis, secretion and action
103738715 (Pik3r1)
04919 Thyroid hormone signaling pathway
103738715 (Pik3r1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
103738715 (Pik3r1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
103738715 (Pik3r1)
09156 Nervous system
04725 Cholinergic synapse
103738715 (Pik3r1)
04722 Neurotrophin signaling pathway
103738715 (Pik3r1)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
103738715 (Pik3r1)
09158 Development and regeneration
04360 Axon guidance
103738715 (Pik3r1)
04380 Osteoclast differentiation
103738715 (Pik3r1)
09149 Aging
04211 Longevity regulating pathway
103738715 (Pik3r1)
04213 Longevity regulating pathway - multiple species
103738715 (Pik3r1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103738715 (Pik3r1)
05206 MicroRNAs in cancer
103738715 (Pik3r1)
05205 Proteoglycans in cancer
103738715 (Pik3r1)
05207 Chemical carcinogenesis - receptor activation
103738715 (Pik3r1)
05208 Chemical carcinogenesis - reactive oxygen species
103738715 (Pik3r1)
05203 Viral carcinogenesis
103738715 (Pik3r1)
05230 Central carbon metabolism in cancer
103738715 (Pik3r1)
05231 Choline metabolism in cancer
103738715 (Pik3r1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103738715 (Pik3r1)
09162 Cancer: specific types
05210 Colorectal cancer
103738715 (Pik3r1)
05212 Pancreatic cancer
103738715 (Pik3r1)
05225 Hepatocellular carcinoma
103738715 (Pik3r1)
05226 Gastric cancer
103738715 (Pik3r1)
05214 Glioma
103738715 (Pik3r1)
05221 Acute myeloid leukemia
103738715 (Pik3r1)
05220 Chronic myeloid leukemia
103738715 (Pik3r1)
05218 Melanoma
103738715 (Pik3r1)
05211 Renal cell carcinoma
103738715 (Pik3r1)
05215 Prostate cancer
103738715 (Pik3r1)
05213 Endometrial cancer
103738715 (Pik3r1)
05224 Breast cancer
103738715 (Pik3r1)
05222 Small cell lung cancer
103738715 (Pik3r1)
05223 Non-small cell lung cancer
103738715 (Pik3r1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103738715 (Pik3r1)
05170 Human immunodeficiency virus 1 infection
103738715 (Pik3r1)
05161 Hepatitis B
103738715 (Pik3r1)
05160 Hepatitis C
103738715 (Pik3r1)
05171 Coronavirus disease - COVID-19
103738715 (Pik3r1)
05164 Influenza A
103738715 (Pik3r1)
05162 Measles
103738715 (Pik3r1)
05168 Herpes simplex virus 1 infection
103738715 (Pik3r1)
05163 Human cytomegalovirus infection
103738715 (Pik3r1)
05167 Kaposi sarcoma-associated herpesvirus infection
103738715 (Pik3r1)
05169 Epstein-Barr virus infection
103738715 (Pik3r1)
05165 Human papillomavirus infection
103738715 (Pik3r1)
09171 Infectious disease: bacterial
05135 Yersinia infection
103738715 (Pik3r1)
05100 Bacterial invasion of epithelial cells
103738715 (Pik3r1)
09174 Infectious disease: parasitic
05146 Amoebiasis
103738715 (Pik3r1)
05142 Chagas disease
103738715 (Pik3r1)
09164 Neurodegenerative disease
05010 Alzheimer disease
103738715 (Pik3r1)
05017 Spinocerebellar ataxia
103738715 (Pik3r1)
05020 Prion disease
103738715 (Pik3r1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103738715 (Pik3r1)
05418 Fluid shear stress and atherosclerosis
103738715 (Pik3r1)
05415 Diabetic cardiomyopathy
103738715 (Pik3r1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103738715 (Pik3r1)
04932 Non-alcoholic fatty liver disease
103738715 (Pik3r1)
04931 Insulin resistance
103738715 (Pik3r1)
04933 AGE-RAGE signaling pathway in diabetic complications
103738715 (Pik3r1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103738715 (Pik3r1)
01524 Platinum drug resistance
103738715 (Pik3r1)
01522 Endocrine resistance
103738715 (Pik3r1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ngi04131
]
103738715 (Pik3r1)
Membrane trafficking [BR:
ngi04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
103738715 (Pik3r1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3K_P85_iSH2
SH2
RhoGAP
SH2_1
SH3_1
SH3_2
Laminin_I
SH3_9
Exonuc_VII_L
Motif
Other DBs
NCBI-GeneID:
103738715
NCBI-ProteinID:
XP_008837055
UniProt:
A0A8C6QVF8
LinkDB
All DBs
Position
Un
AA seq
724 aa
AA seq
DB search
MSAEGYQYRALYDYRKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEDIGWLNGYN
ETTGERGDFPGTYVEYIGRKRISPPTPKPRPPRPLPVAPGSSKTEADSEQQALTLPDLAE
QFAPPDIAPPLLIKLLETIEKKGLECSTLYRTQSSSNPAELRQLLDCDAASVDLEMIDVQ
VLADAFKRYLLDLPNPVIPVAVYSEMMSLAQEVQSSEDFIQVLKKLIRSPNIPHQYWLTL
QYLLKHFFKLSQASSKNLLNPRVLSEIFSPMLFRFPATSSDNTEHFIKVIEVLISTEWNE
RQPAPALPPKPPKSTTVANNSMNNSMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDA
STKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKL
DVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMK
RTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIID
SRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGN
ENAEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACS
VVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA
QQRR
NT seq
2175 nt
NT seq
+upstream
nt +downstream
nt
atgagtgctgaggggtaccagtacagagctctgtatgactacaggaaggagagggaagaa
gacattgacctgcatttgggggacatactgactgtgaataaaggatccttggtggcactt
ggattcagtgatggacaggaagccaggcctgaagatattggctggttaaatggctataat
gaaaccactggggagaggggagactttccaggaacttacgtagaatatattggaaggaaa
agaatctcgcctcccactccaaaacccaggccacctcgacctcttcctgttgcaccaggt
tcctcaaaaactgaagcagatagtgaacaacaagctttgacccttcctgatctggctgag
cagtttgcccctcctgatatcgccccacctctccttatcaagctcctggaaaccatcgag
aagaaaggactggaatgttcgactctatacagaacacagagctccagtaaccctgcagaa
ttacgacagcttcttgattgtgatgctgcctccgtggacttggaaatgattgatgtgcaa
gttttagcagatgctttcaagcgctatcttctggacttaccaaatcctgtcattccagta
gctgtttacagtgaaatgatgtctttagcccaagaagtacaaagctctgaagacttcatc
caggtgttaaagaagctcattaggtcacctaatatacctcatcagtattggcttacactt
cagtatttgctaaaacatttcttcaagctgtctcaagcttccagcaaaaatcttttgaac
ccaagggtcctctctgaaattttcagccctatgcttttcagattcccagcaaccagctct
gataatactgaacacttcataaaagtaatagaagttttaatctcaactgaatggaatgaa
cgacagccagcaccagcactgccccctaagccacccaagtccaccactgtagccaacaac
agcatgaacaacagtatgtctttacaagatgctgaatggtactggggggatatctcaagg
gaagaagtaaatgaaaaactccgagacacagctgatgggacctttttggtacgagatgca
tctactaaaatgcatggcgactacactctcacactaaggaaaggaggaaataacaaatta
atcaaaatatttcaccgtgatggaaaatacggcttctctgacccattaaccttcaattct
gtggttgaactgataaaccactaccggaatgagtctctagcccagtacaatcccaagctg
gatgtcaaattactttacccagtgtccaaataccaacaggatcaggttgtcaaagaagat
aatattgaagctgtagggaaaaagttacatgaatataacactcaatttcaagaaaaaagt
cgggaatatgatagattatatgaggaatacacccgcacttcccaggaaatccaaatgaaa
agaacagctattgaagcatttaatgaaaccataaaaatatttgaagaacagtgccaaacc
caagagcggtacagcaaagaatacattgaaaagtttaagcgtgaaggcaacgagaaggag
attcaaaggattatgcataattatgataagctaaagtctcgcatcagtgagatcattgat
agcagaagaaggttggaagaagacttgaagaagcaggcggccgagtatcgtgagattgac
aagcgcatgaacagcattaagccagacctcattcagctgagaaagacaagagaccaatac
ttgatgtggctgactcaaaaaggcgttcggcaaaagaagttgaacgaatggctgggaaat
gaaaacgcagaagaccaatattcactggtggaggatgatgaggacttgcctcaccatgac
gagaagacgtggaatgttggaagcagcaaccgaaacaaagctgaaaatctattgcgaggg
aagagagacggcacttttcttgtccgggagagcagtaagcaaggctgctacgcctgctct
gtagtggtagatggtgaagtcaagcattgtgtcatcaacaaaactgcgacaggctatggc
tttgcagagccctataacctgtacagctccctgaaggaactggtgctacattaccaacac
acctccctcgtgcagcacaatgactccctcaacgtcacactagcataccctgtatatgca
cagcagaggcgatga
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integrated database retrieval system
