Nannospalax galili (Upper Galilee mountains blind mole rat): 103739378
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Entry
103739378 CDS
T03372
Symbol
Cacna1c
Name
(RefSeq) calcium voltage-gated channel subunit alpha1 C
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04010
MAPK signaling pathway
ngi04020
Calcium signaling pathway
ngi04022
cGMP-PKG signaling pathway
ngi04024
cAMP signaling pathway
ngi04260
Cardiac muscle contraction
ngi04261
Adrenergic signaling in cardiomyocytes
ngi04270
Vascular smooth muscle contraction
ngi04713
Circadian entrainment
ngi04720
Long-term potentiation
ngi04723
Retrograde endocannabinoid signaling
ngi04724
Glutamatergic synapse
ngi04725
Cholinergic synapse
ngi04726
Serotonergic synapse
ngi04727
GABAergic synapse
ngi04728
Dopaminergic synapse
ngi04742
Taste transduction
ngi04911
Insulin secretion
ngi04912
GnRH signaling pathway
ngi04921
Oxytocin signaling pathway
ngi04924
Renin secretion
ngi04925
Aldosterone synthesis and secretion
ngi04927
Cortisol synthesis and secretion
ngi04929
GnRH secretion
ngi04930
Type II diabetes mellitus
ngi04934
Cushing syndrome
ngi04935
Growth hormone synthesis, secretion and action
ngi05010
Alzheimer disease
ngi05020
Prion disease
ngi05022
Pathways of neurodegeneration - multiple diseases
ngi05031
Amphetamine addiction
ngi05207
Chemical carcinogenesis - receptor activation
ngi05410
Hypertrophic cardiomyopathy
ngi05412
Arrhythmogenic right ventricular cardiomyopathy
ngi05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103739378 (Cacna1c)
04020 Calcium signaling pathway
103739378 (Cacna1c)
04024 cAMP signaling pathway
103739378 (Cacna1c)
04022 cGMP-PKG signaling pathway
103739378 (Cacna1c)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
103739378 (Cacna1c)
04929 GnRH secretion
103739378 (Cacna1c)
04912 GnRH signaling pathway
103739378 (Cacna1c)
04921 Oxytocin signaling pathway
103739378 (Cacna1c)
04935 Growth hormone synthesis, secretion and action
103739378 (Cacna1c)
04924 Renin secretion
103739378 (Cacna1c)
04925 Aldosterone synthesis and secretion
103739378 (Cacna1c)
04927 Cortisol synthesis and secretion
103739378 (Cacna1c)
09153 Circulatory system
04260 Cardiac muscle contraction
103739378 (Cacna1c)
04261 Adrenergic signaling in cardiomyocytes
103739378 (Cacna1c)
04270 Vascular smooth muscle contraction
103739378 (Cacna1c)
09156 Nervous system
04724 Glutamatergic synapse
103739378 (Cacna1c)
04727 GABAergic synapse
103739378 (Cacna1c)
04725 Cholinergic synapse
103739378 (Cacna1c)
04728 Dopaminergic synapse
103739378 (Cacna1c)
04726 Serotonergic synapse
103739378 (Cacna1c)
04720 Long-term potentiation
103739378 (Cacna1c)
04723 Retrograde endocannabinoid signaling
103739378 (Cacna1c)
09157 Sensory system
04742 Taste transduction
103739378 (Cacna1c)
09159 Environmental adaptation
04713 Circadian entrainment
103739378 (Cacna1c)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
103739378 (Cacna1c)
09164 Neurodegenerative disease
05010 Alzheimer disease
103739378 (Cacna1c)
05020 Prion disease
103739378 (Cacna1c)
05022 Pathways of neurodegeneration - multiple diseases
103739378 (Cacna1c)
09165 Substance dependence
05031 Amphetamine addiction
103739378 (Cacna1c)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
103739378 (Cacna1c)
05412 Arrhythmogenic right ventricular cardiomyopathy
103739378 (Cacna1c)
05414 Dilated cardiomyopathy
103739378 (Cacna1c)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
103739378 (Cacna1c)
04934 Cushing syndrome
103739378 (Cacna1c)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
ngi04040
]
103739378 (Cacna1c)
Ion channels [BR:
ngi04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
103739378 (Cacna1c)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
GPHH
CAC1F_C
Ca_chan_IQ
PKD_channel
Etmic-2
Motif
Other DBs
NCBI-GeneID:
103739378
NCBI-ProteinID:
XP_017655291
LinkDB
All DBs
Position
Un
AA seq
2189 aa
AA seq
DB search
MVNENTRMYVPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGGTTATRPPRALLCLTLKNPIRRACISI
VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
QEGIVDVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNIFYWLVIFLVFLNTLT
IASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGI
LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
TASPEKKPEVVEKKPAVEETKEEKIELKSITADGESPPTTKINMDDLQPSENEDKGPYSN
PDATGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVND
TIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYV
FTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSVINVVKILXV
LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCS
DSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPE
LLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKN
CELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ
HYGQSCLFKIAMNILNMLFTGLFTVEMILKFIAFKPKGYFSDPWNVFDFLIVIGSIIDVI
LSETNHYFCDAWNTFDALIVVGSIVDKAITKVHPAEHTQCSPSMSAEENSRISITFFRLF
RVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKISLNDTT
EINQNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPGNSTEGEMPCGSSF
AVFYFISFYMLCAFLIISLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGR
IKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRIALR
IKSEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFWKF
KKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAAS
EDDIFRRAGGLFGNHVTYYPSDSRNTFPQTFTTQRPLHINKTGNNQGDTESPSHEKLVDS
TFTPSSYSSTGSNANINNANNTALGHFPHPTSYSSTVSTMEGHGPPLSPAIRVQEAAWKL
SSKRCHSRESQGAMVSREEVLPDETCTVRIGEDTEYCSEPSLLSTEMLSYQDDEHRQLAS
LEEDKREIRQSPKRSFLRSASLGRRASFHLECLKRQKNQGGDISQKTVLPLHLVHHQALA
VAGLSPLLQRSHSPTTFPRPCPTPPVTPGNLGRPLQPIPTLRLEGAESSEKLNSSFPSIH
CSSWSEETTACSGGSSMARRARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFA
QDPKFIEVTTQELADACDMTIEEMENAADNILSGGTQQNPNGTLLPFVNCRDPGEDRAGV
PEDESCAFALGRGRSEEALADSRAFVSNL
NT seq
6570 nt
NT seq
+upstream
nt +downstream
nt
atggtcaatgaaaacaccaggatgtacgttccggaggaaaaccaccaaggttccaactat
gggagcccacgcccagcccatgccaacatgaatgccaatgcagcagcggggctcgcccct
gagcacatccctactccaggggcagccctgtcctggcaggcagccatcgatgccgcccgg
caggccaagctgatgggcagtgctggcaatgcgaccatctctacggtcagctccacacag
cggaagcggcagcagtatgggaaacccaagaagcagggtggtacgaccgccacacggccg
ccccgtgccctgctctgcctgactctgaagaaccctatcaggagggcatgcatcagcatc
gttgaatggaaaccatttgaaataattattttactgactatttttgccaattgtgtggcc
ttagcaatctatattcccttcccagaagatgactccaacgccaccaactccaacctggaa
cgagtggaatatctctttctcataatttttaccgtggaagcatttttaaaagtaattgcc
tatggacttctctttcaccccaacgcttacctccgcaatggttggaatttactagatttt
ataattgtggttgtagggctttttagtgcaattttagaacaagcaaccaaagctgatggg
gccaatgctctaggagggaaaggagctggattcgatgtgaaggcactgagggctttccga
gttctgcgtcccctgcggctggtgtctggagtcccaagtctccaggtggtcctgaactcc
atcatcaaggccatggtgcctctgctgcacattgccttgcttgtgctgttcgtcatcatc
atctacgccatcatcggcctggagctcttcatgggaaagatgcataagacctgctacaac
caggagggcatagtagatgttccagcagaagaggacccttctccttgtgctttggagaca
ggccatgggcggcagtgtcagaatgggaccgtgtgcaagcccgggtgggatgggcccaag
cacggcatcaccaacttcgacaacttcgcctttgccatgctgacagtgttccagtgcatc
accatggagggctggacagatgtgctatactgggtcaatgatgccgtaggaagggactgg
ccctggatctattttgttacactaatcatcatagggtcattttttgtacttaacttggtt
ctcggtgttcttagcggagagttttccaaagagagggagaaggccaaggctcggggagat
ttccagaagcttcgagagaagcagcagctagaagaagatctcaaaggctacctggactgg
atcacccaggcagaagacattgaccctgagaacgaggatgagggcatggatgaagaaaag
ccccgcaacatgagcatgcccacaagtgagactgaatctgtcaacactgaaaatgtggct
ggaggtgacatcgagggcgaaaactgtggagccagactggcccaccggatctccaaatcc
aagttcagccgctactggcgcaggtggaaccgattctgcagaagaaagtgtcgtgcagcc
gtcaagtccaacatcttctactggcttgtgatcttccttgtgttcctcaatacactcacc
attgcctctgaacattacaaccagccccactggctcacagaagtgcaagacacagccaat
aaggccctcctggccctttttactgcagaaatgctcctgaagatgtatagcctaggcctg
caggcctatttcgtatccctcttcaaccgctttgactgcttcatcgtgtgtgggggcatc
ctggagaccatcctggtggagaccaaaatcatgtctcccttgggcatctctgtgctgaga
tgtgtacggctgctcaggatctttaagatcaccaggtactggaactccttgagcaacctc
gtggcatccttgctgaactctgtccgctccattgcctccctgttgcttctccttttcctc
ttcatcatcatcttctcccttctggggatgcagctgtttggaggaaagttcaactttgat
gagatgcagacacgcaggagcacctttgataacttcccgcagtccctcctcactgtgttt
cagatcctgaccggggaggactggaattcggtgatgtatgatgggatcatggcttatggc
ggcccctcttttccagggatgttagtctgtatttacttcatcatcctcttcatctgtgga
aactatatcctactgaatgtgttcttggccattgcggtggacaatctggctgatgcggag
agcctcacctctgcacaaaaggaggaagaagaagagaaagagagaaagaagctggccagg
actgccagcccagagaagaagccggaggtggtagagaagaagccagcggtggaggagacc
aaggaggagaaaattgaactgaagtccattactgcagatggagagtccccacccaccacc
aagatcaacatggatgacctccaacccagtgaaaatgaggataagggtccctactccaac
ccagatgccacaggagaagaggatgaggaggagcctgagatgcctgtggggccacgccct
cggcccctgtctgagctgcaccttaaggaaaaggcagtgcccatgcctgaagccagtgca
tttttcatctttagccccaacaacaggtttcgcctccagtgccaccgcattgtcaatgac
acgatcttcaccaacctgatcctcttcttcattttgctcagcagcatctctctggctgct
gaggaccccgtccagcacacctccttcaggaaccatattctgttttattttgacattgtt
ttcactaccattttcaccattgaaattgctctgaagatcctaggcaatgcagactatgtc
ttcactagtatctttacattagaaattatccttaagatgactgcttatggggctttcctg
cacaagggctctttctgccgaaattacttcaacatcctggacctgctggtggtcagcgtg
tccctcatctcttttggcatccagtccagtgtgatcaacgttgtgaagatcttataagtg
cttcgagtcctcaggcccctcagggccatcaacagagccaaggggctaaagcatgtagta
cagtgtgtgtttgtggccatccggaccatcgggaacattgtaattgtcaccacgctgctg
cagttcatgttcgcctgcattggagtccagctcttcaagggaaaactctacacctgttca
gatagttccaaacagacagaggcagaatgcaagggtaactatatcacatataaagatgga
gaggttgaccatcccattatccagccccgcagctgggagaacagcaagtttgactttgac
aatgttctggcagccatgatggccctcttcactgtctccacctttgaggggtggccagag
ctgctgtatcgctccatcgactcccacacagaagacaagggccccatctacaactaccgt
gtggagatctccatcttcttcatcatttacatcatcatcatcgcctttttcatgatgaac
atctttgtgggtttcgtcatcgtcaccttccaagagcaaggggaacaagagtacaagaac
tgtgagctggacaagaaccagcgacagtgtgtagaatacgccctcaaggcccgacccctg
cggaggtacatccccaagaaccagcaccagtacaaagtgtggtatgtggtcaactctacc
tacttcgagtatctgatgttcgttctcatcctgctcaacaccatctgcctggccatgcag
cactatggccagagctgcctgttcaaaattgccatgaacatactcaacatgctcttcact
ggcctcttcactgtggagatgatcctgaagttcattgccttcaaacccaagggttacttt
agtgatccctggaatgtttttgacttcctcatcgtgattgggagcataattgatgtcatt
ctcagtgagactaatcactatttctgtgatgcatggaatacatttgacgccttgattgtt
gtgggtagcattgttgataaagcaatcaccaaggtacacccagctgaacatacccaatgc
tctccctctatgagtgcagaggagaactcccgcatctccatcaccttcttccgcctcttc
cgggtcatgcgcctggtgaaactgctgagccgcggagaaggcatccggaccctgctgtgg
accttcatcaagtccttccaggccctgccctatgtggcccttctgattgtgatgctgttc
tttatctatgcagtgattgggatgcaggtgtttgggaagatttccctgaatgacaccaca
gagatcaatcagaacaacaacttccagaccttccctcaagctgtgctactgctcttcagg
tgtgccactggggaggcctggcaggacatcatgctggcctgcatgccaggcaagaagtgt
gccccagagtcagagcccggcaacagcacagaaggagagatgccctgtggcagcagtttt
gctgtcttctatttcatcagcttctacatgctctgtgccttcctgatcatcagcctcttt
gtagctgttatcatggacaactttgactacctgacaagggattggtctatccttggtccc
catcatctggatgaatttaaaagaatctgggcagagtatgaccctgaagccaagggtcgg
atcaaacacttggatgtggtgaccctcctccgaaggattcagccgcccctgggctttggg
aagctgtgtcctcaccgtgtggcctgcaaacgcctggtctccatgaatatgcctctgaac
agcgatgggacagtcatgttcaatgccaccctgtttgccctggtcaggatagccctgagg
attaaatcagaagggaacctagaacaagccaatgaggagctgcgagccatcataaagaag
atctggaagaggaccagcatgaagctgctggaccaggtggtgccccctgcaggcgatgat
gaggtcacagtaggcaagttttatgctactttcctgatccaagagtacttctggaaattc
aagaagcgcaaagagcagggactggtgggcaagccctcgcagaggaacgcactatccctg
caggctggcttgcgcacgctgcatgacattggtcctgagatccgccgggccatctctgga
gatctgactgctgaggaggagctggacaaagccatgaaggaggctgtgtctgctgcctcc
gaagatgacatcttcaggagggccggaggcctgtttggcaaccacgtcacctactatcca
agtgacagcaggaatacctttccccagaccttcaccacccagcgcccactgcatatcaac
aagaccggaaacaaccaaggtgacaccgagtcgccatcccatgagaaacttgtggactcc
acgttcacccccagtagctactcatccactggctccaatgccaacatcaacaacgccaac
aacactgccttgggccactttccccaccccaccagctactccagcacagtcagcactatg
gagggccatgggcctcccttgtctcctgctatccgagtacaggaggcagcatggaagctc
agttccaagaggtgccactcacgagagagccagggagccatggtgagtagggaggaggta
ttaccagatgagacgtgcacggtgcggatcggtgaagatactgagtactgcagcgagccc
agcctgctctccacagagatgctctcctaccaggatgatgaacatcgacaactagcatct
ctagaggaggacaagagggagatccggcagtctccaaagaggagtttccttcgctctgcc
tctcttggtcgaagggcttccttccacctggaatgtctgaagcgacaaaagaatcaaggg
ggagatatctctcagaagacagtcctgcccttgcatctggttcatcatcaggcgttggca
gtggcaggcttgagccccctcctacagagaagccattcccctaccacattccccaggcca
tgccccacgccccctgtcactccaggcaacctgggcaggcccctgcagcccatccccacc
ctacggctggagggggctgagtccagcgagaaactcaatagcagcttcccatccatccac
tgcagctcctggtctgaggagaccactgcctgtagtgggggcagcagcatggcccggaga
gcccggcctgtctccctcactgtgcccagccaggctggagctcctggaagacagttccac
ggcagtgccagcagcctggtggaagcggtcttgatttctgaaggactggggcagttcgct
caagatcccaagttcatcgaggtcactacccaggagctggctgatgcctgcgacatgacg
atagaggagatggagaatgccgcagacaacatcctcagtgggggcacccagcagaacccc
aatggcaccctcttaccttttgtgaactgcagggaccccggggaggacagggctggggtc
ccggaggacgagagctgtgcatttgccctgggccggggccgcagcgaggaggcgctcgcg
gacagtagggccttcgtcagcaacctgtag
DBGET
integrated database retrieval system
