Nannospalax galili (Upper Galilee mountains blind mole rat): 103741353
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Entry
103741353 CDS
T03372
Symbol
Hmgcs1
Name
(RefSeq) 3-hydroxy-3-methylglutaryl-CoA synthase 1
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00280
Valine, leucine and isoleucine degradation
ngi00650
Butanoate metabolism
ngi00900
Terpenoid backbone biosynthesis
ngi01100
Metabolic pathways
ngi03320
PPAR signaling pathway
Module
ngi_M00095
C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
103741353 (Hmgcs1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
103741353 (Hmgcs1)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
103741353 (Hmgcs1)
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
103741353 (Hmgcs1)
Enzymes [BR:
ngi01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
103741353 (Hmgcs1)
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Motif
Pfam:
HMG_CoA_synt_C
HMG_CoA_synt_N
Cullin
Motif
Other DBs
NCBI-GeneID:
103741353
NCBI-ProteinID:
XP_008840337
UniProt:
A0A8C6W5Y9
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All DBs
Position
Un
AA seq
520 aa
AA seq
DB search
MPGSLPLNTEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCT
DREDINSLCLTVVQNLMERNSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDI
EGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAIYATGNARPTGGVGAVALL
IGPNAPLIFDRGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYRKKI
RAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKSLARMFLNDFLNDQNRDKNSIYSGLEA
FGDVKLEDTYFDRDVEKAFMKASSELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQY
SPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTCVAP
DVFAENMKLREDTHHLANYIPQCSIDSLFEGTWYLVRVDEKHRRTYARRPSPSDHTLDEG
VGLVHSNTATEHIPSPAKKVPRLPATPAESEAAVISNGEH
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgcctgggtcacttcctttgaatacagaagcttgctggccaaaagatgtgggaattgtt
gcccttgagatctattttccttctcaatatgttgatcaagccgagttggaaaaatatgat
ggtgtagatgccggaaagtataccattggcttgggccaggccaggatgggcttctgcaca
gatcgagaagacatcaattctctttgcctgactgtggttcagaatctgatggagagaaat
agcctttcctatgattgcattgggcggctagaagttggaacagagacaatcatcgacaag
tccaaatcagtgaagtctaatttgatgcagctgtttgaggagtctggcaacacagatata
gaaggaatagatacaactaatgcttgctatggaggcacagctgctgtcttcaacgctgtg
aactggattgagtccagctcttgggatggacggtatgcactggtagttgcgggagatatt
gctatatatgccacaggaaatgccagacctacaggtggagttggagctgtggctctgtta
attgggccaaatgctcctttaatttttgaccgagggcttcgtggaacacatatgcagcat
gcctacgacttttacaagcctgatatgctctccgaataccctatagtagatggaaaactc
tccatacagtgctacctcagtgcattagaccgctgctattctgtctatcgcaaaaagatc
cgtgctcagtggcagaaagagggaaatgataaagattttaccctgaatgattttggcttc
atgatctttcactcaccatactgtaaactggttcagaaatctctagctcggatgttcctg
aatgactttcttaatgatcagaacagagacaaaaatagtatctacagtggcctggaagcc
tttggggatgttaaattagaagatacttactttgacagagatgtggaaaaggcatttatg
aaggctagttctgaactatttaaccagaaaacaaaggcatctttgcttgtatcaaatcaa
aatggaaatatgtatacatcttctgtgtatggttcccttgcttctgttttagcacagtat
tcaccccagcagttggcagggaagaggattggtgtattctcttatggttctggtttggct
gccactctgtactcccttaaagttacacaagatgccacaccagggtctgctcttgacaaa
ataacagcaagtttatgtgaccttaaatcaaggcttgactcgagaacttgtgtagcacct
gatgtctttgctgaaaacatgaagctcagagaagacactcatcacttagccaactatatt
cctcagtgttcaatagattcactcttcgaaggaacatggtacctggttagagtagatgaa
aagcatagaagaacttatgcccggcgtccctctcccagcgatcatactttagatgaagga
gtaggacttgtacattcaaacacagcaacagagcatattccgagcccggctaagaaagtg
ccaagactccctgcaacaccagcagaatctgaagcagctgtcattagtaatggggaacat
taa
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