Nannospalax galili (Upper Galilee mountains blind mole rat): 103741433
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Entry
103741433 CDS
T03372
Symbol
Adcy1
Name
(RefSeq) adenylate cyclase 1
KO
K08041
adenylate cyclase 1 [EC:
4.6.1.1
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00230
Purine metabolism
ngi01100
Metabolic pathways
ngi01522
Endocrine resistance
ngi04015
Rap1 signaling pathway
ngi04020
Calcium signaling pathway
ngi04022
cGMP-PKG signaling pathway
ngi04024
cAMP signaling pathway
ngi04062
Chemokine signaling pathway
ngi04072
Phospholipase D signaling pathway
ngi04081
Hormone signaling
ngi04082
Neuroactive ligand signaling
ngi04114
Oocyte meiosis
ngi04211
Longevity regulating pathway
ngi04213
Longevity regulating pathway - multiple species
ngi04261
Adrenergic signaling in cardiomyocytes
ngi04270
Vascular smooth muscle contraction
ngi04371
Apelin signaling pathway
ngi04540
Gap junction
ngi04611
Platelet activation
ngi04713
Circadian entrainment
ngi04714
Thermogenesis
ngi04720
Long-term potentiation
ngi04723
Retrograde endocannabinoid signaling
ngi04724
Glutamatergic synapse
ngi04725
Cholinergic synapse
ngi04727
GABAergic synapse
ngi04750
Inflammatory mediator regulation of TRP channels
ngi04911
Insulin secretion
ngi04912
GnRH signaling pathway
ngi04913
Ovarian steroidogenesis
ngi04914
Progesterone-mediated oocyte maturation
ngi04915
Estrogen signaling pathway
ngi04916
Melanogenesis
ngi04918
Thyroid hormone synthesis
ngi04921
Oxytocin signaling pathway
ngi04923
Regulation of lipolysis in adipocytes
ngi04925
Aldosterone synthesis and secretion
ngi04926
Relaxin signaling pathway
ngi04927
Cortisol synthesis and secretion
ngi04928
Parathyroid hormone synthesis, secretion and action
ngi04934
Cushing syndrome
ngi04935
Growth hormone synthesis, secretion and action
ngi04970
Salivary secretion
ngi04971
Gastric acid secretion
ngi04972
Pancreatic secretion
ngi04976
Bile secretion
ngi05032
Morphine addiction
ngi05142
Chagas disease
ngi05146
Amoebiasis
ngi05163
Human cytomegalovirus infection
ngi05166
Human T-cell leukemia virus 1 infection
ngi05200
Pathways in cancer
ngi05207
Chemical carcinogenesis - receptor activation
ngi05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103741433 (Adcy1)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
103741433 (Adcy1)
04371 Apelin signaling pathway
103741433 (Adcy1)
04020 Calcium signaling pathway
103741433 (Adcy1)
04072 Phospholipase D signaling pathway
103741433 (Adcy1)
04024 cAMP signaling pathway
103741433 (Adcy1)
04022 cGMP-PKG signaling pathway
103741433 (Adcy1)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
103741433 (Adcy1)
04081 Hormone signaling
103741433 (Adcy1)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
103741433 (Adcy1)
09144 Cellular community - eukaryotes
04540 Gap junction
103741433 (Adcy1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103741433 (Adcy1)
04062 Chemokine signaling pathway
103741433 (Adcy1)
09152 Endocrine system
04911 Insulin secretion
103741433 (Adcy1)
04923 Regulation of lipolysis in adipocytes
103741433 (Adcy1)
04912 GnRH signaling pathway
103741433 (Adcy1)
04913 Ovarian steroidogenesis
103741433 (Adcy1)
04915 Estrogen signaling pathway
103741433 (Adcy1)
04914 Progesterone-mediated oocyte maturation
103741433 (Adcy1)
04921 Oxytocin signaling pathway
103741433 (Adcy1)
04926 Relaxin signaling pathway
103741433 (Adcy1)
04935 Growth hormone synthesis, secretion and action
103741433 (Adcy1)
04918 Thyroid hormone synthesis
103741433 (Adcy1)
04928 Parathyroid hormone synthesis, secretion and action
103741433 (Adcy1)
04916 Melanogenesis
103741433 (Adcy1)
04925 Aldosterone synthesis and secretion
103741433 (Adcy1)
04927 Cortisol synthesis and secretion
103741433 (Adcy1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
103741433 (Adcy1)
04270 Vascular smooth muscle contraction
103741433 (Adcy1)
09154 Digestive system
04970 Salivary secretion
103741433 (Adcy1)
04971 Gastric acid secretion
103741433 (Adcy1)
04972 Pancreatic secretion
103741433 (Adcy1)
04976 Bile secretion
103741433 (Adcy1)
09156 Nervous system
04724 Glutamatergic synapse
103741433 (Adcy1)
04727 GABAergic synapse
103741433 (Adcy1)
04725 Cholinergic synapse
103741433 (Adcy1)
04720 Long-term potentiation
103741433 (Adcy1)
04723 Retrograde endocannabinoid signaling
103741433 (Adcy1)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
103741433 (Adcy1)
09149 Aging
04211 Longevity regulating pathway
103741433 (Adcy1)
04213 Longevity regulating pathway - multiple species
103741433 (Adcy1)
09159 Environmental adaptation
04713 Circadian entrainment
103741433 (Adcy1)
04714 Thermogenesis
103741433 (Adcy1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103741433 (Adcy1)
05207 Chemical carcinogenesis - receptor activation
103741433 (Adcy1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103741433 (Adcy1)
05163 Human cytomegalovirus infection
103741433 (Adcy1)
09174 Infectious disease: parasitic
05146 Amoebiasis
103741433 (Adcy1)
05142 Chagas disease
103741433 (Adcy1)
09165 Substance dependence
05032 Morphine addiction
103741433 (Adcy1)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
103741433 (Adcy1)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103741433 (Adcy1)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
103741433 (Adcy1)
Enzymes [BR:
ngi01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
103741433 (Adcy1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Guanylate_cyc
AC_N
Adcy_cons_dom
HNOBA
DUF6594
Motif
Other DBs
NCBI-GeneID:
103741433
NCBI-ProteinID:
XP_008840410
LinkDB
All DBs
Position
Un
AA seq
894 aa
AA seq
DB search
MYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK
PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR
RIKILGDCYYCVSGLTQPKADHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL
CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSF
LKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS
NVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQPELEMADL
NFFTLKYKHVEREQKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFSI
CFLVACVLYLHITRVQCFPGCLTIQIRTILCIFIVVLIYSVAQGCVVGCLPWAWSSQSNS
SLVVLAAGGRRTVLPALPCESAHHALLCCLVGTLPLAIFLRVSSLPKMILLSGLTTSYIL
ILELSGYTKAGGGALSGRSYEPIMAILLFSCTLALHARQVDVRLRLDYLWAAQAEEERDD
MERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELD
GNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGARARKSIS
SHLSTLADFAIDMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNV
ASRMDSTGVQGRIQVTEEVHRLLRRCSYQFVCRGKVSVKGKGEMLTYFLEGRTDGNSTHS
RSLRLERRMCPYGRGGGQARRPPLCPAAGPPIRRGLPPAPTGQYLPSTAAGKEA
NT seq
2685 nt
NT seq
+upstream
nt +downstream
nt
atgtatggtgtcttcgtgcggatcctgactgagcgctcacagaggaaggccttcttgcag
gctcgaagctgcattgaggaccggctgcggctggaggatgagaacgagaagcaggagcgg
ctgctcatgagcctcttgccccggaatgttgccatggagatgaaggaagacttcttgaag
ccccctgagaggattttccacaagatttacatccagagacatgacaacgtgagcatcctg
tttgcagatatcgtgggcttcacaggtctggcatcccagtgcacagctcaggagctggtg
aaactgctcaacgagctctttggcaagttcgatgagttagctacggagaaccactgtcgc
cgcatcaagatccttggagactgctactactgcgtatctggcctcacccagcccaaggcc
gaccatgctcactgctgcgtggagatgggccttgacatgattgataccatcacatctgtg
gctgaggctaccgaggtagacctgaacatgcgtgtgggtctgcacaccggcagggtcctc
tgcggagtcctgggcctgcgcaagtggcagtacgatgtgtggtccaatgacgtgactctg
gccaacgtcatggaagctgctggactgccagggaaggttcacatcacaaagacgacactt
gcatgtttgaatggtgactacgaggtcgagccaggtcacggacatgagagaaacagcttc
ctgaaaactcacaacatcgagaccttctttattgtgccatcccatcggaggaagatattt
ccaggcttgattctctcagatataaagccagccaagaggatgaagttcaagactgtctgc
tacctgctggtgcagctcatgcactgccggaagatgttcaaggctgagatccccttctct
aatgtgatgacctgcgaggatgatgacaagcggagagcattgagaacagcctcagaaaaa
ctcagaaaccgctcgtctttttctacaaacgtggtctacaccactccaggcacacgtgtc
aacaggtatatcagccgccttcttgaagcccgccagccagagctggagatggctgatctg
aacttctttaccctgaagtacaaacatgttgaacgggagcaaaaataccaccagcttcag
gatgagtacttcaccagtgctgtcgtcctcgccctcatcctggctgccttatttgggctt
gtctaccttctgataatcccacagagtgtggctgtcctgctcctgctggtgttctctatc
tgctttctggtggcctgtgtcctgtacctgcacatcacacgggtccagtgtttcccaggg
tgcctgacgatccagatccgcaccatcttgtgcatattcatagtggtcttaatctactca
gtagctcaaggatgtgtggtgggctgcctgccctgggcctggagctctcagtccaacagt
tccctggtggtccttgcggctggtggccggcgcactgtgctgcctgccctgccctgtgag
tctgcacaccatgccctgctctgctgcctggtgggcaccctcccactagccatattcctg
cgggtgtcctccttgccaaagatgatcctgctgtctgggctgaccacatcctacatcctc
atcctggagctcagtggttacaccaaggctgggggtggtgccctctctgggcgcagttat
gagccaatcatggctatcctgctgttctcatgcacactggccctgcacgccaggcaagtg
gatgtcagactgcggctggactacctctgggcagcacaggcagaagaggagcgtgatgac
atggagagggtgaagctggacaacaagaggatcctcttcaacctcctgccagcccatgtg
gcacagcacttcctcatgtccaatcccaggaacatggacctctactatcagtcctactcc
caggtgggtgtcatgtttgcctccattcccaacttcaatgacttctacattgagcttgat
ggcaacaacatgggagtagaatgtctgcggctcctcaacgagatcattgctgacttcgat
gagctcatggacaaggacttttacaaggacctagagaagatcaagaccatcgggagcacc
tacatggctgcagtggggctggcgcccacagcaggagccagggcgaggaagtccatctct
tcccacctgagcacactggctgactttgccattgacatgtttgatgtcctggatgaaatc
aactaccaatcatacaacgactttgttctccgagttggcatcaacgttggccctgtggtg
gctggagtgattggcgctcgaagaccccaatatgacatctggggaaatacagtcaatgtg
gccagtcggatggacagcactggggtccagggcagaatccaggtgactgaggaggtccac
cggctgctgaggaggtgctcttaccagtttgtatgccgaggcaaagtcagcgtcaagggc
aagggagagatgctaacatactttctagaaggcaggactgatggaaacagcacccacagc
aggtctcttcgcttggagcggaggatgtgtccatatgggagaggaggaggccaggccagg
cggcccccattatgtcctgcagctggacccccgatcagacgtgggctccccccagccccc
acaggccagtatctaccatccacagcagcagggaaagaagcctag
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