Nannospalax galili (Upper Galilee mountains blind mole rat): 103744649
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Entry
103744649 CDS
T03372
Symbol
Alk
Name
(RefSeq) anaplastic lymphoma receptor tyrosine kinase
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi05200
Pathways in cancer
ngi05223
Non-small cell lung cancer
ngi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103744649 (Alk)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103744649 (Alk)
09162 Cancer: specific types
05223 Non-small cell lung cancer
103744649 (Alk)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ngi01001
]
103744649 (Alk)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ngi04090
]
103744649 (Alk)
Enzymes [BR:
ngi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103744649 (Alk)
Protein kinases [BR:
ngi01001
]
Receptor tyrosine kinases (RTK)
ALK family
103744649 (Alk)
CD molecules [BR:
ngi04090
]
Proteins
103744649 (Alk)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
MAM
ALK_LTK_GRD
Ldl_recept_a
FXa_inhibition
Motif
Other DBs
NCBI-GeneID:
103744649
NCBI-ProteinID:
XP_008844703
LinkDB
All DBs
Position
Un
AA seq
1622 aa
AA seq
DB search
MQALGLRWLLLQLLSAAAWGFRASADQRAGFPVAGPPLQPREPLSYSRLQRKSLAVDFVV
PSLFRVYARDLLLPPPPSPSEPRTGGPEARGSLALDCAPLLRLLGPRLGVSWAAGTSSPS
SEGGPTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPEEAAAVGLLQFNLSELFS
WWIRHGEGRLRIRLMPEKKASEMGREGKLSAAIRASQPRLLFQIFGTGHSSLESPSSTPS
PDNFVWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHNHGNQSWSWRRVPSEE
ASQMDLLDGPEAEHSKEMPRGSFLLLNTSADSKHTILSPWMRSSSEHCMLAVSVHRHLQP
SGRYIAQLLPHNEAGREILLVPTPGKHGWTVLQGRIGRPENPFRVALEYISSGNRSLSAV
DFFALRNCSEGTSPGSKMALQSSFTCWNGTVLQLGHACDFHRDCAQGEDEGPLCSKLPAG
FYCNFEDDFCGWTQSILSPHMPQWQVRNLKNAQSQGRQGHALLLSTTDVPTSESATVTSA
TFPAPMKNSPCELRMSWLIRGVLRGNVSLVLVENKTGKEQSRMVWHVATNDASNEGLSLW
QWTVLSLLDVSDRFWLQIVVWWGQGSRATVAFDNISISLDCYLTISGEDKMPLNAAPKSR
NLFERNSHKDSKANVSGTTPIFDPTVHWLFTTCGASGPYGPTQAQCNNAYQNSNLSVVVG
NEGPLKGIQIWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDTLYILV
GQQGEDACPSTNQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATFVFKMKDGVP
VPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLLWAGKS
LLEGATGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGEDG
VSFISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLA
EDGVSCIVSPTPEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQS
PEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQV
SGTPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFIL
LELMAGGDLKSFLRETRPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNC
LLTCAGTGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSF
GVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPN
FAIILERIEYCTQDPDVINTALPIEYGPVVEEEEKVPMRPKDPEGMPPLLVSPPAKHEDA
PAAPQQQSAQAAPAKAVKKAPAAGAGSSRVPRGPAAEGGHVNMAFAQSNPPAELHKAPGS
RNKPTSLWNPTYGSWFAEKPAKKHAPRAAAEPQGRAGAGCEGGWTRPGVPGPRGAGAALL
LEPSALTASMKEVPLFRLRHFPCGNVNYGYQQQGLPLEATAGAGHLEDSVLKNKSSATQP
GP
NT seq
4869 nt
NT seq
+upstream
nt +downstream
nt
atgcaagcccttgggctccggtggctgctgctacagctgctttcggcggcagcctggggc
ttccgcgcctcagcggatcagcgcgcgggcttcccggtcgcagggccgccactgcaaccc
cgggagccgctcagctactcgcgcctgcagaggaagagtctggcggtggacttcgtggtg
ccctcgctcttccgcgtttacgctcgagacctgctgctgccgccgccgccgtctccctcg
gagcctaggactggcgggccggaggcgaggggctcgctggctctggactgtgcccctctg
ctcagactgctggggccccggctcggggtctcctgggcagcaggcaccagctcgcccagt
tcagaaggaggtccgacgctgtccagggtgctgaagggaggctctgtgcgcaagctccgg
cgagccaagcagctggtgctggagctgggcgaggaggcgatcctggagggctgcgttggg
cccccagaggaggcagcggctgtggggttgctccagttcaacctcagcgagctgtttagc
tggtggattcgccacggcgaagggcggttgaggatccgcctgatgccggagaagaaggct
tcggaaatgggcagggagggaaagctgtcggcggctatccgtgcctcccagccccgcctt
ctcttccagatcttcgggaccggtcacagctccttggagtcaccctcaagcactccttct
cctgataattttgtgtggaatctgacctggataatgaaagattccttccctttcctgtcc
catcgcagtcgatatggtctggagtgcagctttgacttcccttgtgaactggaatactct
cctccattgcataatcatgggaaccagagctggtcctggcgtcgtgtgccctctgaggag
gcgtcgcagatggacttgttggatgggccagaggcagagcattctaaagagatgcccaga
ggctccttcctcctcctgaacacctctgcagattccaagcacaccatcctgagcccgtgg
atgaggagcagcagtgagcactgcatgctggctgtctcggtgcataggcatctacagcct
tctgggagatacattgctcagctactgccccacaatgaggctggaagagagattctcttg
gtgcctactccagggaagcatggctggacagtgctgcagggaaggatcgggcgcccagag
aatccattccgagtggccctggaatacatctccagtggaaaccgaagcttgtctgcagtg
gacttctttgccctgaggaactgcagtgaaggaacatccccaggctccaagatggccctg
cagagctccttcacttgttggaatgggacagttctccagctggggcatgcctgtgacttc
caccgggactgtgctcagggagaagacgagggaccgctgtgcagtaaacttcctgctggg
ttttactgcaactttgaagatgacttctgtggttggacccaaagcatactctcaccccac
atgccccagtggcaagtcaggaacctgaagaatgcccagtcccagggtcgccaaggtcat
gccctattgctcagtaccactgatgttcccacttctgaaagtgcgacggtgaccagtgct
acatttcctgcaccgatgaagaactctccttgtgagctccggatgtcctggctcatccgt
ggagttttgagaggaaatgtgtccttggtgctggtggagaacaaaaccggaaaggagcaa
agtcggatggtctggcatgttgccaccaatgatgcctcaaatgaaggcttgagcctatgg
cagtggacagtattgtctcttctcgatgtgtctgacaggttctggctgcagatagtcgta
tggtggggtcaaggatccagggcaacggtggcgtttgacaatatctccatcagcctggac
tgctacctcaccatcagtggggaggataagatgcccctgaatgcagcacccaaatccaga
aatctgtttgagagaaactcacacaaggattcaaaggccaatgtatcaggaacaactccc
atctttgaccctacagttcactggctgtttaccacatgtggggccagtggaccctatggc
cccacacaggcccagtgcaacaatgcctaccagaactccaatctgagcgtggtggtgggg
aacgaagggcccttgaagggcatccagatttggaaagtgccagccacagacacctacagc
atctcaggctatggagcagctggcgggaaaggcgggaagaacaccatgatgcggtcccat
ggagtatctgtgctgggtattttcaacctggagaaggatgacacgttatacatcctggtc
gggcaacagggagaggatgcctgtcctagtacaaaccaactaatccagaaagtttgcatc
ggagagaacaacgtgatagaagaagagatccgtgtgaacagaagcgtgcatgagtgggca
ggaggaggaggaggtgggggtggagccaccttcgtgtttaagatgaaagatggcgtgccg
gtacccctgatcattgcagctggcggtggtggcagggcctacggggccaagacagacacg
ttccacccagaaagattggagaataactcctcagttctagggctgaatggcaattccgga
gccgcaggtggtggaggcggctggaatgataacacttccttgctctgggccggaaagtct
ttgctggagggtgccacaggaggacattcctgcccccaggccatgaagaagtgggggtgg
gagacaagagggggtttcggagggggtggaggggggtgctcctcaggtggaggaggcgga
ggatatataggtggcaatgcagcatcaaacaatgacccagaaatggatggggaagatggg
gtttctttcatcagtccattgggtatcctgtacaccccagccttaaaagtgatggagggc
catggggaggtgaatatcaagcattacctaaactgcagtcactgtgaggtagatgaatgc
cacatggaccccgagagccacaaggtcatctgcttctgtgaccatgggaccgtactggct
gaggatggtgtctcctgcattgtgtcacccaccccggagccccatctgccactctcgctg
atcctctccgtcgtgacctctgccctggtggctgccctcgtcctggcattctctggcatc
atgattgtgtaccgccggaaacaccaggagctgcaagccatgcagatggaactgcagagc
cctgagtacaagctgagcaagctgcgcacctcgaccatcatgacggactacaaccccaac
tactgctttgccggcaagacttcatccatcagtgacctgaaggaggtgccacggaaaaac
atcaccctcatccggggcctgggccatggcgcatttggagaagtgtatgaaggccaggtg
tctggaacgcccaatgacccaagccccctacaagtggctgtaaagacgctgccagaagtg
tgttcagaacaggacgagctggatttcctcatggaagccctgatcatcagcaaattcaac
caccagaacatagtgcgctgcatcggagtgagtctgcaagccctgccccgcttcattctg
ctggagctcatggcaggtggagacctcaagtccttcctccgagagacacgccctcgccct
aaccagccctcctcactggccatgctggatcttctgcacgtggctcgggacattgcctgc
ggctgtcagtaccttgaggaaaaccacttcatccaccgggacattgctgctagaaactgc
cttttgacttgtgctggaactggaagaatagcaaagattggggactttgggatggctcga
gacatctacagagccagctactacagaaagggagggtgtgccatgctgccagtgaaatgg
atgcctccagaggccttcatggaaggaatatttacttctaaaactgacacatggtctttt
ggagtgttgctgtgggaaatattttctcttgggtatatgccataccccagtaaaagtaac
caggaagttctggagtttgtcaccagtggaggacggatggacccacctaagaactgcccc
gggcctgtataccggataatgactcagtgctggcagcatcaacctgaagacagacccaac
tttgccatcattttggagaggattgaatactgcacccaggacccagatgtcatcaacacc
gctctgcccatagagtatggcccggtggtggaagaggaggagaaagtacccatgaggccc
aaagaccccgaggggatgccccctctgctggtgtctccgcccgccaagcacgaggacgcg
cccgcggccccgcagcagcagtccgcccaggcggcgcccgccaaagcggtgaagaaggcc
ccggccgcgggcgcgggctccagccgggtccctcgaggccctgccgccgagggggggcac
gtgaacatggcgttcgctcagtccaacccgccggccgagctgcacaaggccccgggatcc
agaaacaagccgaccagcctgtggaacccgacctacggctcgtggttcgcggagaaaccg
gctaaaaagcacgctcctcgggcggccgcggagccgcagggccgggcaggtgcgggctgc
gagggcggctggacccggccgggcgtgcccgggccgcgaggagccggggcggcgctgctg
ctcgagccgtcggcgctgacagccagcatgaaggaggtgcctctgttcaggctgcgccac
ttcccctgcgggaacgtcaactatggctaccagcagcagggcctacccctggaggccacg
gcgggggccggccacttggaggacagtgttctgaaaaacaagagcagcgcgacccagccc
gggccctga
DBGET
integrated database retrieval system
