Nannospalax galili (Upper Galilee mountains blind mole rat): 103746695
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Entry
103746695 CDS
T03372
Symbol
Acacb
Name
(RefSeq) acetyl-CoA carboxylase beta
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00061
Fatty acid biosynthesis
ngi00620
Pyruvate metabolism
ngi00640
Propanoate metabolism
ngi01100
Metabolic pathways
ngi04152
AMPK signaling pathway
ngi04910
Insulin signaling pathway
ngi04920
Adipocytokine signaling pathway
ngi04922
Glucagon signaling pathway
ngi04931
Insulin resistance
ngi04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
103746695 (Acacb)
00640 Propanoate metabolism
103746695 (Acacb)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
103746695 (Acacb)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
103746695 (Acacb)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
103746695 (Acacb)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
103746695 (Acacb)
04922 Glucagon signaling pathway
103746695 (Acacb)
04920 Adipocytokine signaling pathway
103746695 (Acacb)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
103746695 (Acacb)
04931 Insulin resistance
103746695 (Acacb)
Enzymes [BR:
ngi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
103746695 (Acacb)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
103746695 (Acacb)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
103746695 (Acacb)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
103746695
NCBI-ProteinID:
XP_008847188
UniProt:
A0A8C6RKL1
LinkDB
All DBs
Position
Un
AA seq
2456 aa
AA seq
DB search
MVLLLLSCLIFCCLTFSWFKICGKMMDSKPVTNSKMEASGTPTEEPFPASHSSEESLQKP
SGGSSLPKTPDRVEPASHRDHRDGCRQRASLPPSHQKPPRNPQSSNDTWPSPELQANGTE
VQDQEASDTNGLSSPARPPDQQAASPSKEDKKQAHIKRQLMTNFILGSFDDNSSDEDPGA
GSFRVSSRKGSRASLGTLSLEASVISESESHEPTIRPSMSGLHLVRRGREHKKLDLHRDF
TVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPE
DLKANAEYIRMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPE
LLCKHEIAFLGPPSKAMWALGDKIASTIVAQTLEIPTLPWSGSGLTVEWTEDGLQQGKCI
SVPEDVYNQGCVKDVDEGLEAAEKIGFPVMIKASEGGGGKGIRKAESAEDFPMLFRQVQS
EIPSSPIFLMKLAQHARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPVTIATPA
VFEFMEQCAVRLAKTVGYVSAGTVEYLYSPDGSFYFLELNPRLQVEHPCTEMIADVNLPA
AQLQIAMGVPLHRLKDLRLLYGESPWAVTPISFETPSNLPLARGHVIAARITSENPDEGF
KPSSGTVQELNFRSSKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALK
ELSIRGDFRTTVEYLINLLETESFQNNDTDTGWLDHLIAERVQAEKPDIMLGVVCGALNV
ADSMFRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGIKYILKVARQSLTMFVLIMNG
CHIEIDAHRLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSA
GKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQETGRVKYIKRPGVVLEAGCVVARLE
LDDPSKVHAAEPFIGKLPAQQTLPILGEKLHQVFHSVLENLTNVMSGYCLPEPFFSIKLK
EWVQKLMMTLRHPSLPLLELQEIMTSIAGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQ
QIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKTVVLDLLRRYLQVEH
HFQQAHYDKCVINLREQFKPDMTQVLDCIFSHAQVAKKNQLVIMLIDEVCGPDPALSDEL
TSILSELTQLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN
LKKLILSETTIFDVLPTFFYHTNKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVE
FQFMLPSSHPNRMAVPISIINPDLLRRSTELFMDSGFSPLCQRMGAMVAFRRFEEFTRNF
DEVISCFANIPTDTPLFSKARTSLYSEDDSKNLREEPIHILNVAIQCVDHLEDEALVPIF
RTFIQSKKHILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLEL
SRMRNFDLTAVPCANHKMHLYLGAAKVREGLEVTDHRFFIRAIIRHSDLITKEASFEYLQ
NEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRSMVMRYGSRL
WKLRVLQAEVKINIRQTTMDCAVPIRLFITNESGYYLDISLYKEVTDARSGNIMFHSFGN
KQGSQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPEKYPKDV
LTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTPEYPEGRDIIVISNDITFHIGSF
GVGEDFLYLRASEMARIEGIPKVYLAANSGARLGLAEEIKHIFQVAWVDPKDPHKGFKYL
YLTPQDYTRISSQNSVHCKHIEDDGESRYVIVDIIGKDSNLGVENLSGSGMIAGEASLSY
EEVVTISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGG
VQIMHTNGVSHVTVPDDFEGVCTILEWLSYIPKDNHSPVPIITPTDPIGREIEFIPSRAP
YDPRWLLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETR
TVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQVIRDFNREQLPLMIFANWRGFSG
GMKDMYEQMLKFGAYIVDGLRQYKQPILLYIPPYAELRGGSWVVLDSTINPLCIEMYADK
ESRGGVLEPEGTVEIKFRKKDLVKTMKRMDPMCKKLLEQLGTAQLPDKDRRELEAQLKAR
EDLLFPIYHQVAVQFADLHDTPGRMLEKGTISDVLEWRTSRTFLYWRLRRLLLEAQVKQE
ILHASPELSHEHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWPARDSLHSAIHEN
IKCLKQDSVLKTIQGLVQKNPEVAMDCIVYLSQHLSPAERIQIVQLLSTTESPASP
NT seq
7371 nt
NT seq
+upstream
nt +downstream
nt
atggtcttgcttcttctgtcttgcctgattttctgctgcctgaccttttcctggttcaaa
atctgtggaaaaatgatggattccaagccagtcaccaacagtaagatggaagcaagtggc
actccaactgaggagccttttccagcctcacacagctcagaggagtcgctacaaaaaccc
agtggtggcagctctctgccaaagactcctgaccgagtggagccagcctcccacagggac
cacagagacgggtgtcggcagagggcctccctgccaccctcacaccagaagccgcctagg
aacccccagtcttccaatgacacttggccttccccagaactccaagccaatgggacagag
gtccaagaccaggaggcctcagataccaatggcctgtcctccccagccagacccccggac
cagcaagccgcatccccctccaaagaggacaagaagcaagcgcacatcaagaggcagctg
atgaccaacttcatcctgggctccttcgatgacaactcctctgatgaggatcctggtgct
ggctcatttagggtctcttcccggaagggtagccgggccagcctgggcaccctgtccctg
gaggcttcagtcataagtgaatctgagtctcacgaacccactataaggcccagcatgtct
ggactccacctagtgaggaggggccgtgagcacaagaagctggacctgcacagagacttc
actgtggcatccccagctgagtttgtcacccgctttgggggagatcgggtcattgagaag
gtgctcattgccaacaacggcattgcggcagtcaagtgcatgcgctccattcgccgctgg
gcctatgagatgttccgcaacgaacgggccatccgctttgtggtcatggtgacccctgaa
gacctcaaggccaatgcagaatacatcaggatggccgatcagtatgtcccagtgccagga
gggcccaataacaacaactacgcaaatgtggagctgatcgtagacattgccaagagaata
cctgtgcaggccgtgtgggctggctggggccatgcttccgaaaaccccaaacttccggag
ctgctgtgcaaacacgagattgctttcttaggtccgcccagtaaggccatgtgggccctg
ggagataagatcgcctccaccattgtggcccagacactggagatcccaaccctgccctgg
agcggaagtggtctcacagtggagtggacagaggatggcctgcagcagggcaaatgtatc
agtgtccccgaagatgtttacaaccagggttgtgtgaaggatgtggatgagggcttggag
gcagcagagaagattgggtttccagtgatgatcaaagcttctgaaggtgggggagggaaa
gggatccgtaaagcggagagcgctgaagacttccccatgcttttcagacaagtgcagagt
gagatccccagctcgcccatttttctcatgaagctggctcagcacgcacgacacctggag
gtgcaggtcctggctgaccagtacggaaatgcggtgtctctgtttgggcgggactgctcc
atccagaggcggcaccagaagatcatcgaggaggctccagttaccattgccacaccagct
gtgtttgagttcatggaacagtgtgctgtccgcctggccaagaccgtgggctatgtgagc
gctggcacggtggaatacttgtacagcccagacggcagtttctacttcctagagctgaat
ccccgactacaggtggagcatccctgcactgaaatgatcgcagatgtcaatctgcctgct
gcgcagctgcagatcgctatgggggtgccgctgcaccggctgaaggacctcaggcttctg
tatggagagtccccctgggcagtgacccctatttcttttgagactccttccaaccttccc
cttgcccgaggtcatgtcattgcggccagaatcaccagcgaaaatccagatgagggcttt
aagccaagctccgggacagtccaggaactgaatttccgcagtagcaagaacgtgtggggt
tacttcagcgtggctgcagctgggggcttacacgagttcgccgactcccagtttggccac
tgcttctcctggggcgagaaccgtgaagaggccatttcgaacatggtggtggctttgaag
gaactgtccatccggggtgacttccggactaccgtggagtacctcattaacctcctggag
actgagagcttccagaacaacgacactgacactgggtggctggaccacctcattgctgag
agggtgcaggcagagaagccagacatcatgctcggagtggtgtgtggggccttgaacgtg
gcagattcgatgttcagaacctgcatgacggatttcttgcactccttggaaaggggccag
gtcctcccagctgattctctgctgaacattgtggatgtagagttgatttatggaggtatc
aagtacattctcaaggtggcccggcagtccctgactatgttcgttctcatcatgaatggc
tgccacatcgagattgatgcccacaggctcaatgatgggggactgctcctatcatacaat
ggcagcagctacaccacttacatgaaggaagaggtggacagttaccgaatcactattggc
aacaagacgtgtgtttttgaaaaggagaatgaccccacggtcctgagatccccctcagct
gggaagctgacacagtacacagtggaggacggaggccatgttgaagctgggagcagctat
gcggagatggaggtgatgaagatgatcatgaccttgaatgtgcaggaaactggccgggta
aagtacatcaagcgtccaggggtcgtgctggaagctggctgtgtggtggctagattagag
cttgatgacccttcaaaagtgcatgcggcggaaccgttcatagggaagctccctgcccag
cagactctgcccatcctgggggagaagctgcaccaggtgttccacagtgtcctggaaaac
ctgaccaatgtcatgagtggctactgcctgccagagcctttcttcagcataaagctgaaa
gagtgggtgcagaaactgatgatgaccctccgacacccgtcgctgccactgctggagctg
caagaaatcatgaccagcatagcaggccgcatccccgcccccgtggagaaagcagtccgc
agggtgatggcccaatatgccagtaacatcacctcagtgctgtgccagttccccagccag
cagatagccaccatcctggactgccacgccgccaccctgcagcgaaaggctgaccgagag
gtcttcttcatgaacacacagagcatcgtgcagctggtccagagataccgcagcggaacc
cgtggctacatgaaaaccgtggtactggacctcctgcggagatacttacaagtggagcat
catttccaacaagcacactatgacaagtgcgtgatcaacctcagggagcagttcaagcca
gatatgacccaggtgctggactgcatcttctcgcatgcacaggtggccaagaagaaccag
ctggtgatcatgctgattgatgaggtctgtggtccagaccctgccctgtcagacgagctg
acctccatcctcagtgagcttactcagctgagcaggagcgagcattgcaaggtggccctc
agagccaggcaggtcctgattgcctcccacctcccctcctacgagctgcggcacaaccaa
gtggagtccatctttctgtctgccattgacatgtatggacaccaattctgcccagaaaac
ctcaagaaattaatactctcggaaacaactatatttgacgtgctgcccactttcttctac
cacaccaacaaagtcgtctgcatggcgtcgttggaggtttatgtgcggagaggctacatc
gcctatgagctgaacagcctgcagcaccgagagctcccagacggtacctgtgtggtggag
ttccagtttatgctgccctcttcccaccccaaccggatggcagtacccatcagcatcatt
aaccctgacctgctgaggcgcagcacagagctcttcatggacagtggtttctccccactg
tgccagcggatgggggccatggtagccttcaggagatttgaggaattcaccaggaacttt
gatgaagttatctcctgctttgccaacattcccacagacacacccctcttcagcaaggcc
cgcacctccctgtactctgaggatgatagcaagaacctccgagaagagcccatccacatc
ctgaatgtggccattcagtgtgtggaccacctggaggatgaggcactggtgccgattttc
cggaccttcatacagtctaagaaacatatccttgtggattacggactccgaagaatcaca
ttcctgattgcccaagagaaagaattccccaagttcttcacgttcagagcacgggatgag
tttgccgaagacaggatttaccgccatttggagcccgccctggccttccagctggagctg
agcaggatgcgcaactttgacctgactgctgtgccctgtgccaaccacaagatgcacctt
tacctgggcgctgccaaggtgagggaagggctggaggtgacggaccacaggttcttcatc
cgcgccatcatcaggcactcggacctgatcaccaaggaagcctccttcgagtacctacag
aatgagggtgaacggctgctcttggaggccatggacgagctggaggtggcattcaacaac
accagtgtgcgcaccgactgtaaccacatcttcctcaattttgtgcccactgtcatcatg
gacccattcaagatcgaggagtcagtgcgcagcatggtcatgcgctatggcagccggctg
tggaaactccgtgtgctgcaggctgaggtcaagatcaacatccgccaaacgaccatggac
tgtgctgttcccatccgcctattcatcaccaatgagtcaggctactacctggacatcagc
ctctacaaagaagtcaccgatgccagatctggaaacatcatgtttcattcctttggcaac
aagcaagggagccagcatgggatgctcatcaacactccctatgtcaccaaagatcttctc
caggccaagcgattccaggcgcagtctttggggaccacctatgtgtacgacttcccggaa
atgtttcggcaggccctctttaaactgtggggctccccagaaaagtaccccaaagatgtc
ctgacatacaccgagctggtgttggactcccagggccagctggtggagatgaaccggctt
cccggtgggaatgaggtgggcatggtggccttcaaaatgaggtttaagactccagagtat
ccagaagggcgggacatcattgtcatcagcaacgacatcaccttccacatcggctctttc
ggcgtaggagaggacttcctgtacctgcgggcatctgagatggcccggatagagggcatc
cccaaagtctatctggctgccaacagtggggcccgacttggcctggctgaggagatcaaa
catatattccaagtggcctgggtggaccccaaagatccccacaaaggatttaaatacctg
tacctgaccccccaagactacacccgaatcagttcccagaactccgtgcactgcaaacac
attgaggatgacggtgaatccaggtacgtcattgtggacatcattgggaaggatagcaac
ctgggcgtagaaaacctgagcggctcgggcatgattgcaggagaggcctccctgtcttat
gaagaggtcgtcaccattagcatggtgacctgccgtgcccttggaatcggggcctacttg
gtgaggcttggccaacgggtgatccaggtggagaattcccacatcattctcactggagcc
agcgctctcaacaaggttctgggaagagaggtctacacatctaataaccagctgggaggt
gtacagatcatgcataccaatggtgtctcccatgtcactgtgccagatgacttcgaggga
gtctgtaccatattggagtggctgtcctatataccgaaggataatcacagccctgtcccc
atcatcacacccactgaccccattggcagagaaattgaattcatcccatccagagctccc
tacgacccccggtggctgcttgcaggaagacctcacccaactctgaagggaacctggcag
agtgggttcttcgaccatggcagtttcaaggaaatcatggcaccttgggcccagactgtg
gtgacaggacgagccagactgggtggcatccctgtgggagtgattgccgtggagacgagg
actgtggaggtggccgttcctgcagaccctgctaacctggattctgaggccaagataatc
cagcaggccggccaagtgtggtttccggactctgcctacaaaacggcgcaggtcatcagg
gacttcaaccgggagcagctgcctctcatgatctttgccaactggaggggcttctccggt
ggcatgaaggacatgtatgaacagatgttgaagtttggagcctacatcgtggacggcctc
cggcaatacaagcagcccatcctcctctacattcccccttatgctgagctccgagggggc
tcctgggtcgtcctggactccaccatcaatcccctgtgcatagaaatgtatgcggacaaa
gagagcagggggggtgtcctggaaccagagggcacagtggagattaagttccggaagaaa
gatctggttaagaccatgaaaagaatggacccaatgtgcaagaagctcctggaacagtta
gggactgcccagctgcctgacaaggaccgaagggagctggaagcccagctgaaggctcgt
gaggacctcctgttccccatctaccaccaggtggcggtgcagtttgctgacctgcatgac
accccaggccgaatgctagagaaaggaaccatctctgacgtgctggagtggaggacttca
cgcacctttctctattggcgcctgcgccggctgctgctggaggcccaagtaaagcaggag
attctgcatgccagccctgagctgagccatgagcacatacagtccatgctgcgccgctgg
tttgtggaaacagagggcgccgtcaaggcctacctgtgggacaacaaccaggtggtggtc
cagtggctggagcagcactggccagccagggacagcctacactctgccatccatgagaac
atcaagtgcctgaagcaggactctgtccttaagaccatccaaggtctggttcagaaaaac
ccagaggtggccatggactgcattgtgtacctgagccagcacctcagccctgctgagcgg
atacagattgttcagctgctgtctaccacagagagcccagcttccccctga
DBGET
integrated database retrieval system
