KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103747342
Entry
103747342         CDS       T03372                                 
Symbol
Fos
Name
(RefSeq) Fos proto-oncogene, AP-1 transcription factor subunit
  KO
K04379  proto-oncogene protein c-fos
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01522  Endocrine resistance
ngi04010  MAPK signaling pathway
ngi04024  cAMP signaling pathway
ngi04210  Apoptosis
ngi04380  Osteoclast differentiation
ngi04620  Toll-like receptor signaling pathway
ngi04657  IL-17 signaling pathway
ngi04658  Th1 and Th2 cell differentiation
ngi04659  Th17 cell differentiation
ngi04660  T cell receptor signaling pathway
ngi04662  B cell receptor signaling pathway
ngi04668  TNF signaling pathway
ngi04713  Circadian entrainment
ngi04725  Cholinergic synapse
ngi04728  Dopaminergic synapse
ngi04915  Estrogen signaling pathway
ngi04917  Prolactin signaling pathway
ngi04921  Oxytocin signaling pathway
ngi04926  Relaxin signaling pathway
ngi04928  Parathyroid hormone synthesis, secretion and action
ngi04932  Non-alcoholic fatty liver disease
ngi04935  Growth hormone synthesis, secretion and action
ngi05031  Amphetamine addiction
ngi05132  Salmonella infection
ngi05133  Pertussis
ngi05135  Yersinia infection
ngi05140  Leishmaniasis
ngi05142  Chagas disease
ngi05161  Hepatitis B
ngi05162  Measles
ngi05166  Human T-cell leukemia virus 1 infection
ngi05167  Kaposi sarcoma-associated herpesvirus infection
ngi05170  Human immunodeficiency virus 1 infection
ngi05171  Coronavirus disease - COVID-19
ngi05200  Pathways in cancer
ngi05207  Chemical carcinogenesis - receptor activation
ngi05208  Chemical carcinogenesis - reactive oxygen species
ngi05210  Colorectal cancer
ngi05224  Breast cancer
ngi05231  Choline metabolism in cancer
ngi05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ngi05323  Rheumatoid arthritis
ngi05417  Lipid and atherosclerosis
ngi05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103747342 (Fos)
   04668 TNF signaling pathway
    103747342 (Fos)
   04024 cAMP signaling pathway
    103747342 (Fos)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    103747342 (Fos)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103747342 (Fos)
   04660 T cell receptor signaling pathway
    103747342 (Fos)
   04658 Th1 and Th2 cell differentiation
    103747342 (Fos)
   04659 Th17 cell differentiation
    103747342 (Fos)
   04657 IL-17 signaling pathway
    103747342 (Fos)
   04662 B cell receptor signaling pathway
    103747342 (Fos)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    103747342 (Fos)
   04917 Prolactin signaling pathway
    103747342 (Fos)
   04921 Oxytocin signaling pathway
    103747342 (Fos)
   04926 Relaxin signaling pathway
    103747342 (Fos)
   04935 Growth hormone synthesis, secretion and action
    103747342 (Fos)
   04928 Parathyroid hormone synthesis, secretion and action
    103747342 (Fos)
  09156 Nervous system
   04725 Cholinergic synapse
    103747342 (Fos)
   04728 Dopaminergic synapse
    103747342 (Fos)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103747342 (Fos)
  09159 Environmental adaptation
   04713 Circadian entrainment
    103747342 (Fos)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103747342 (Fos)
   05207 Chemical carcinogenesis - receptor activation
    103747342 (Fos)
   05208 Chemical carcinogenesis - reactive oxygen species
    103747342 (Fos)
   05231 Choline metabolism in cancer
    103747342 (Fos)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103747342 (Fos)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103747342 (Fos)
   05224 Breast cancer
    103747342 (Fos)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103747342 (Fos)
   05170 Human immunodeficiency virus 1 infection
    103747342 (Fos)
   05161 Hepatitis B
    103747342 (Fos)
   05171 Coronavirus disease - COVID-19
    103747342 (Fos)
   05162 Measles
    103747342 (Fos)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103747342 (Fos)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103747342 (Fos)
   05135 Yersinia infection
    103747342 (Fos)
   05133 Pertussis
    103747342 (Fos)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    103747342 (Fos)
   05142 Chagas disease
    103747342 (Fos)
  09163 Immune disease
   05323 Rheumatoid arthritis
    103747342 (Fos)
  09165 Substance dependence
   05031 Amphetamine addiction
    103747342 (Fos)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103747342 (Fos)
   05418 Fluid shear stress and atherosclerosis
    103747342 (Fos)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    103747342 (Fos)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103747342 (Fos)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ngi03000]
    103747342 (Fos)
   04131 Membrane trafficking [BR:ngi04131]
    103747342 (Fos)
Transcription factors [BR:ngi03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Fos
    103747342 (Fos)
Membrane trafficking [BR:ngi04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    103747342 (Fos)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 bZIP_Maf MIC19_MIC25 DUF3450 HALZ Macoilin
Other DBs
NCBI-GeneID: 103747342
NCBI-ProteinID: XP_008847938
UniProt: A0A8C6QPG8
LinkDB
Position
Un
AA seq 380 aa
MMFSGFNTDYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF
IPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGVPTPATGAYSRAGVLKTMSGGRA
QSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQ
TEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVTSLDLTGGLPEAATPDSEEAFT
LPLLNDPEPKPSVEPVKSVSSIELKAEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYA
ADWEPLHSGSLGMGPMVTELEPLCTPVVTCTPSCTTYTSSFIFTYPEADSFPSCAAAHRK
GSSSNEPSSDSLSSPTLLAL
NT seq 1143 nt   +upstreamnt  +downstreamnt
atgatgttctcgggcttcaacaccgactacgaggcgtcatcctcccgctgcagcagcgcc
tcccccgccggggacagcctctcttactaccattccccggccgactccttctccagcatg
ggctctccggtcaatgcgcaggacttctgcacagatctggctgtctccagtgccaacttc
atccccacagtgactgccatctccaccagcccagacctgcagtggctggtgcagcccacc
ctggtctcctctgtggccccgtcgcagactagagcgccccacccctacggagtccccacc
cccgcgaccggggcttactccagggcgggagtgctgaagaccatgtccggaggcagagcc
cagagcatcggaaggaggggcaaagtagaacagttatctcccgaagaagaagagaaaagg
agaatccgaagggaaaggaataagatggctgcagccaaatgccgcaaccggaggagggag
ctgacggacactctccaagcggagacagaccaacttgaagacgaaaagtctgctttgcag
actgagattgccaatctgctgaaagagaaagaaaaactggagttcatattggcagctcac
cgacctgcctgcaagattcctgatgacctgggcttcccagaagagatgtctgtgacctcc
ctggatttgactgggggtctgcctgaggctgccaccccagattccgaggaggccttcacc
ctgccccttctcaatgaccctgagcccaagccatcggtggagccggtcaagagcgtcagt
agcatagagctgaaggctgagccctttgatgacttcctgttcccagcatcatccaggccc
agtggatcggagaccgcccgctctgtgccagacatggacctgtctggttctttctatgca
gcagactgggagcccctgcacagcggctccctagggatggggcccatggtcacagagctg
gagcccctgtgcaccccggtggtcacctgtactcctagctgcactacttacacgtcttcc
ttcatcttcacctaccccgaggctgactccttccccagctgtgcagctgcccaccgcaag
ggcagcagtagcaacgagccctcctctgactcactcagctcacccacactgctggccctg
tga

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