KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103751514
Entry
103751514         CDS       T03372                                 
Symbol
Tgfb1
Name
(RefSeq) transforming growth factor beta 1
  KO
K13375  transforming growth factor beta-1
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04010  MAPK signaling pathway
ngi04060  Cytokine-cytokine receptor interaction
ngi04068  FoxO signaling pathway
ngi04110  Cell cycle
ngi04148  Efferocytosis
ngi04218  Cellular senescence
ngi04350  TGF-beta signaling pathway
ngi04380  Osteoclast differentiation
ngi04390  Hippo signaling pathway
ngi04659  Th17 cell differentiation
ngi04672  Intestinal immune network for IgA production
ngi04926  Relaxin signaling pathway
ngi04932  Non-alcoholic fatty liver disease
ngi04933  AGE-RAGE signaling pathway in diabetic complications
ngi05140  Leishmaniasis
ngi05142  Chagas disease
ngi05144  Malaria
ngi05145  Toxoplasmosis
ngi05146  Amoebiasis
ngi05152  Tuberculosis
ngi05161  Hepatitis B
ngi05166  Human T-cell leukemia virus 1 infection
ngi05200  Pathways in cancer
ngi05205  Proteoglycans in cancer
ngi05210  Colorectal cancer
ngi05211  Renal cell carcinoma
ngi05212  Pancreatic cancer
ngi05220  Chronic myeloid leukemia
ngi05225  Hepatocellular carcinoma
ngi05226  Gastric cancer
ngi05321  Inflammatory bowel disease
ngi05323  Rheumatoid arthritis
ngi05410  Hypertrophic cardiomyopathy
ngi05414  Dilated cardiomyopathy
ngi05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103751514 (Tgfb1)
   04350 TGF-beta signaling pathway
    103751514 (Tgfb1)
   04390 Hippo signaling pathway
    103751514 (Tgfb1)
   04068 FoxO signaling pathway
    103751514 (Tgfb1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    103751514 (Tgfb1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103751514 (Tgfb1)
  09143 Cell growth and death
   04110 Cell cycle
    103751514 (Tgfb1)
   04218 Cellular senescence
    103751514 (Tgfb1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    103751514 (Tgfb1)
   04672 Intestinal immune network for IgA production
    103751514 (Tgfb1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    103751514 (Tgfb1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103751514 (Tgfb1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103751514 (Tgfb1)
   05205 Proteoglycans in cancer
    103751514 (Tgfb1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103751514 (Tgfb1)
   05212 Pancreatic cancer
    103751514 (Tgfb1)
   05225 Hepatocellular carcinoma
    103751514 (Tgfb1)
   05226 Gastric cancer
    103751514 (Tgfb1)
   05220 Chronic myeloid leukemia
    103751514 (Tgfb1)
   05211 Renal cell carcinoma
    103751514 (Tgfb1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103751514 (Tgfb1)
   05161 Hepatitis B
    103751514 (Tgfb1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    103751514 (Tgfb1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103751514 (Tgfb1)
   05144 Malaria
    103751514 (Tgfb1)
   05145 Toxoplasmosis
    103751514 (Tgfb1)
   05140 Leishmaniasis
    103751514 (Tgfb1)
   05142 Chagas disease
    103751514 (Tgfb1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    103751514 (Tgfb1)
   05321 Inflammatory bowel disease
    103751514 (Tgfb1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    103751514 (Tgfb1)
   05414 Dilated cardiomyopathy
    103751514 (Tgfb1)
   05415 Diabetic cardiomyopathy
    103751514 (Tgfb1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    103751514 (Tgfb1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103751514 (Tgfb1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:ngi03110]
    103751514 (Tgfb1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ngi04052]
    103751514 (Tgfb1)
   00536 Glycosaminoglycan binding proteins [BR:ngi00536]
    103751514 (Tgfb1)
Chaperones and folding catalysts [BR:ngi03110]
 Intramolecular chaperones
  Others
   103751514 (Tgfb1)
Cytokines and neuropeptides [BR:ngi04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   103751514 (Tgfb1)
Glycosaminoglycan binding proteins [BR:ngi00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   103751514 (Tgfb1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta CBM96
Other DBs
NCBI-GeneID: 103751514
NCBI-ProteinID: XP_008853215
UniProt: A0A8C6QFC4
LinkDB
Position
Un
AA seq 390 aa
MPPSGLRLLPLLLPLLWLLVLSPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESADPEPEPEADYYAKEVTRVLMVERNNAI
YDKIKDIPHSVYMFFNTSDLREAVPDPLLLSRAELRLQRFKSSVEQHVELYQRYSNNSWR
YLSNRLLTPTDTPEWLSFDVTGVVRQWLSQGDGIQGFRFSAHCSCDSKDNVLHVEINGIS
PKRRGDLGTIHDMNRPFLLLMATPLERAQHLHSSRNRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQA
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgccgccctcggggctgcggctgctgccgctgctgctcccgctactgtggctactggtg
ctgtcgccgggccggccagccgcagggctctccacctgcaagaccatcgatatggagctg
gtgaagcggaagcgcatcgaggccatccgtggccagatcctgtccaaactacggctcgcc
agccccccgagccagggggaggtgccgcccggcccgctgcccgaggccgtgctcgccctg
tacaacagcacccgcgaccgggtggccggggagagcgccgaccccgaacccgagcccgaa
gcggactactatgccaaagaggtcacccgcgtgctaatggtggagcgcaacaacgcaatc
tatgataaaatcaaggacatcccacacagtgtgtatatgttcttcaatacgtcagacctt
cgggaagcagtgcctgatccgcttttgctgtcccgggcagagctgcgtctgcagaggttc
aagtcaagtgtggagcaacacgtggaactgtaccagagatacagcaataattcatggcgc
tacctcagcaaccggctgctgactcccacagatacgcccgagtggttgtcttttgatgtc
actggagtcgtacggcagtggctgagccaaggagatggaatacagggattccgcttcagt
gcccactgctcttgtgacagcaaagataacgtgctccatgtggaaatcaacgggatcagt
cccaaacgccgaggtgacctgggtaccattcatgacatgaaccggcccttcctgctcctc
atggccaccccactggagagggcccagcacctgcacagctccaggaaccgccgagccctg
gacaccaactactgcttcagttccacagagaagaattgctgtgtgcggcagctctacatt
gactttcgaaaggacctgggctggaaatggatccatgagcccaagggctaccatgccaac
ttctgtctggggccctgtccttacatttggagcctggacactcagtacagcaaggtcctg
gctctctacaaccagcacaaccccggggcgtcggcgtcgccgtgctgcgtgccgcaggcg
ctggagccgttgcccatagtgtactacgtgggccgcaagcccaaggtggagcagctgtcc
aacatgatcgtgcgctcctgcaagtgcagctga

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