Nannospalax galili (Upper Galilee mountains blind mole rat): 103751919
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Entry
103751919 CDS
T03372
Symbol
Brca1
Name
(RefSeq) BRCA1, DNA repair associated
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01524
Platinum drug resistance
ngi03440
Homologous recombination
ngi03460
Fanconi anemia pathway
ngi04120
Ubiquitin mediated proteolysis
ngi04151
PI3K-Akt signaling pathway
ngi05206
MicroRNAs in cancer
ngi05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
103751919 (Brca1)
09124 Replication and repair
03440 Homologous recombination
103751919 (Brca1)
03460 Fanconi anemia pathway
103751919 (Brca1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
103751919 (Brca1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
103751919 (Brca1)
09162 Cancer: specific types
05224 Breast cancer
103751919 (Brca1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
103751919 (Brca1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
ngi01009
]
103751919 (Brca1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
ngi04121
]
103751919 (Brca1)
03036 Chromosome and associated proteins [BR:
ngi03036
]
103751919 (Brca1)
03400 DNA repair and recombination proteins [BR:
ngi03400
]
103751919 (Brca1)
Enzymes [BR:
ngi01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
103751919 (Brca1)
Protein phosphatases and associated proteins [BR:
ngi01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
103751919 (Brca1)
Ubiquitin system [BR:
ngi04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
103751919 (Brca1)
Multi subunit type E3
BRCC complex
103751919 (Brca1)
Chromosome and associated proteins [BR:
ngi03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
103751919 (Brca1)
DNA repair and recombination proteins [BR:
ngi03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
103751919 (Brca1)
BRCA1-A complex
103751919 (Brca1)
BRCA1-B complex
103751919 (Brca1)
BRCA1-C complex
103751919 (Brca1)
BRCA complex
103751919 (Brca1)
FA (Fanconi anemia) pathway
Downstream FA components
103751919 (Brca1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
BRCT_2
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_2
zf-C3HC4_3
zf-RING_5
RING_XB3-XBAT31
zf-ANAPC11
zf-RING_6
zf-Nse
zf-RING_10
RTT107_BRCT_5
zf-rbx1
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
103751919
NCBI-ProteinID:
XP_008853744
LinkDB
All DBs
Position
Un
AA seq
1675 aa
AA seq
DB search
MKKILECPICLELIQEPVSTKCDHIFCKFCMLKLLNQKRGPSQCPLCKNEITKRSLQEST
RFSQLVEELLKITHAFELDTGLQFANSYSFLKKENKSSEHSHEESSVIECVGYRNRTKRL
RQNEPGNPTLQEDSFSDQLSNLGIVRPLKKNQQIRPQNKSVYIELGSDSSEDTVTKPNYY
NVRDQELLEITPQRSKAEAAEKADCEFSEDVANIEHHQSSNRDLNTIGSHSVEKHSEKYQ
GTSTSNLHEEPCGTDIHASLLQHENGSLLLTEDRMDVEMAELCSKSKQSGLAGSQQSRWA
GSKKTCHDRQSHSTEKKADLNADPLDEREKWNKQKAPSSESLSDTQDTPCVTLNSSIRKV
NEWFSKSGKMFTSYGTSDRHEASAEGAGTFEVSNEVEACSGSSEKIDLLASDPHNASVCR
SETVCSKPVERNIKDKIFGKTYQRKGSLPNLNHVTEILRAFASEPQITQEHPFTNKLKRR
RRTASCLHPEDFIKKADLTVVQKTSENINQGADQMEQNGQVLNITNGGHENKINDDNVQK
EKNPNPVESLEKESAFRTKAEPISNSISSLELELNVHNSKAPKKNRLRRKSSNRHILALE
LVSGNPSPPTHTILQIDSCSSSEETKGNNSNQMPVRHGKKHQLLEDAEPAAGSKESDEPD
ERVSRRGAGDVFSALKLTNTPGLLTNCSSSNKPQEFVSPHPQRKAIEKLETSKELKDPML
SEERGWSERSPESTSTSLVPDTDHGSQNSVSLLEPNTLRNANQGMAQYIACEKPKEPIYD
SKDTGNCTEGFKHPLGLELNHIQETSIDTEESELDTQYLQNICQVSKRQSFALVSNPRNP
EKESTTACAHSVFLRKLSPKPSLVREQKEKNQGWEESKISHIQAFNTTGDFAVVCQDDTP
GNDAKCTGVSRLCPSFQFRGRECELISADKPGISQNLHLKQSLSSIRSSVKTDHRKTLLE
ERFVEHSLPTEKAMDNEISIQSPVHTISQDSRENPCKEGSSDSVNEVGPSDEDFQEQLDR
NRGPRLSTVLRRSLMQPEAYKQSFPISDCKHPEIKKQEAQASSANISPCLFSEQLEQTMR
SGSVSQVCSETPDDLFDVDEIEENTSFGEGDIMERSAVFTKSILRREVSRSPVLLTHTSL
ARSHQKRSRKLESSSSEDEDLPCFQHLLGKVTSTSQITKHSPAVTQRLSEKTENQEPLKN
SINDCNSEMSLAEGSQEHHLSEDGKYSASMFSSQHSELEDVASNTNSQDLLFNSSKQMSH
PSENQEVVLSDKELISDDEEMESSLEKDNQEENEISDLDEAASAYEGEANLSEDSSQSDI
LTSQQRATMKVNLIKIQQEMAQLEAVLERQENLPSCCSTSLLADPCVPKDLLNPEQNVSK
TEVIPYLESGVTLFSRSHPESELSKEKAPEPAHVSISALKISQCQAAEYSKSPAAAHSTD
TEVAKTVSKTKSKWTSSKGRDKKISMVVSGLTHKEIMIVQKFAEKYHVTLSDVITEETTH
VIIKTDAEFVCERTLKYFMGIARGKWIVSYLWVIQSIKKRKLLNEQEFEVRGDVVNGRNH
QGPRRSRESQEKIFRGLEICCCEPFSSMPRDQLERILQMCGASVVKELSSLTFGTGTQPV
VVLQPSAWTERNDYLDIEKMCEAPVVMWDWVLDSISLYQRQNLETYLISACHPTS
NT seq
5028 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaaatcttagagtgtccaatctgtctggaattgatccaagaaccagtatccaca
aagtgtgaccacatattttgcaagttttgtatgctgaaacttctcaaccagaagagaggg
ccttcacagtgtcctttgtgtaagaatgagataaccaaaagaagcctccaagaaagtaca
agatttagtcaacttgttgaagaactattgaaaatcactcatgcttttgagcttgacaca
ggattgcaatttgcaaatagttacagttttttgaaaaaggaaaataagtcttctgaacat
tcacatgaggagtcttctgtcattgagtgtgtgggctaccgaaaccgtaccaaaagactt
cggcagaatgagcctggaaatcccaccttgcaggaagacagtttcagtgaccaactctct
aatcttggaattgtgagacctctgaagaaaaatcaacagataaggcctcaaaataaatct
gtctacattgaattaggatctgattcttctgaagacaccgttactaagccaaattattac
aatgtgagagatcaagaattgctagaaatcactcctcaaagatccaaggctgaagctgca
gaaaaggctgattgtgagttttctgaggacgtagcaaatattgaacatcatcagtccagt
aatagagatttgaacaccattgggagtcattcagttgagaagcattcagaaaagtatcag
ggtacttctacttcaaacttgcatgaggagccatgtggcacagatattcatgccagctta
ttacagcatgagaatggcagtttattactcactgaagacagaatggatgtagaaatggct
gaactctgtagtaaaagcaaacagtctggcttagcagggagccaacagagcagatgggct
ggaagtaagaaaacatgtcatgatagacagagtcacagcacagagaaaaaggcagatctg
aatgctgatccccttgatgaaagagaaaaatggaataaacagaaggctccctcctctgag
agtcttagtgacacccaagatactccttgtgtaacactaaatagcagcattcggaaagtt
aatgaatggttttccaaaagtggtaaaatgttcacgtcttatggtacatctgacaggcat
gaggcaagtgctgaaggagctggtacatttgaggtttcaaatgaagtagaagcatgttct
ggttcttcagagaaaatagacttactggcttctgatcctcataatgcttcagtatgcaga
agtgaaacagtctgctccaaaccagtagagaggaatatcaaagataaaatatttgggaaa
acctatcagagaaagggaagccttcctaacttgaaccatgtgactgaaattttaagagca
tttgcttcagaaccacagatcacacaagagcatcccttcacaaataaattaaagcgtaga
aggagaactgcatcatgccttcatcctgaggattttatcaagaaagcagatttaacagtt
gttcaaaagacttctgaaaatataaatcagggagctgaccaaatggagcagaatggtcaa
gtgctaaatattaccaatggtggtcatgagaacaaaataaatgatgataatgttcagaaa
gagaaaaatcctaacccagtagaatcattggaaaaagagtctgctttcagaactaaagcc
gaacctataagcaacagtataagcagtttggaactagaattaaatgttcacaattcaaaa
gcacctaagaagaataggctcaggaggaagtcttctaacaggcatattcttgctcttgag
ctagtcagtgggaatccaagtccacctactcatactatacttcaaattgatagttgtagt
agcagtgaagaaacaaagggaaataattccaaccaaatgccagtgaggcatgggaaaaag
catcagctcctagaagatgcagaacctgcagctggctccaaggagagtgatgagccagat
gagcgagtaagcaggagaggtgctggtgatgtcttctcagcactgaaactaacaaatact
cctggcttattaaccaactgttcgagttctaataaacctcaagaatttgtcagtcctcac
cctcagagaaaagcaatagagaaacttgaaacaagcaaagagctcaaagatcctatgcta
agtgaagaaaggggttggtctgaaagatctccagagagtacgagtacttcattggtccct
gatacagatcatggctctcagaacagtgtctctttactggaacctaacactctcaggaat
gcaaatcagggtatggctcagtatatagcttgtgaaaaacccaaggaacctatatatgat
tctaaagatactggaaactgtacagagggcttcaagcatccattgggacttgaacttaac
cacattcaagaaacaagcatagacacggaagagagtgaactggatactcagtacttacaa
aatatatgccaggtctcaaagcgtcaatcatttgctctagtttcaaatcccagaaatcca
gaaaaggagtctacaacagcctgtgcccactctgtgttcttaaggaagctgagtccaaaa
ccgtctcttgtacgtgagcaaaaagaaaaaaatcaggggtgggaagagtctaaaatcagt
catatacaggcatttaataccacaggagactttgctgtggtttgtcaggacgatactcca
ggtaatgatgcaaagtgtacaggagtctctaggctttgtccatcatttcagttcagaggc
agggaatgtgaactcatctctgcagataaacctggaatttcacaaaatttgcatcttaaa
caatcactttcttccatcaggtcatctgtaaaaactgaccatagaaaaactttgttggag
gaaaggtttgtggaacattcattaccaactgaaaaggcaatggacaatgagatcagcatt
caaagtccagtgcatacaattagtcaagatagcagagaaaatccttgtaaagaaggtagc
tcagacagtgttaatgaagtaggtcccagtgatgaagactttcaagaacagctagataga
aacagaggacccaggttaagcactgtgctcagaagaagtcttatgcaacctgaagcctat
aagcaaagttttcctataagtgattgtaaacatcctgaaataaaaaagcaagaagcccag
gctagtagtgcaaacatctctccatgtctattttcagaacaactagagcaaacaatgaga
agtggcagtgtttctcaggtttgttctgagacacctgatgacctgtttgacgttgatgag
atagaggaaaatactagctttggggaaggtgacataatggaaaggtctgctgtttttacc
aagagtatcctgagaagagaggtcagcaggagccctgtccttttaacccatacatcactg
gctcgaagtcaccaaaaaaggtctaggaaattagaatcctcatctagtgaggatgaagat
cttccctgcttccaacacttacttggcaaagtaaccagtacatctcaaattaccaaacat
agccctgcagtgacacagcgtttgtcagagaaaacagagaaccaagaaccgttgaagaat
agcataaatgactgtaatagtgagatgagcttggcagagggatcccaggaacatcacctt
agcgaggacggaaaatactccgctagcatgttctcttcacagcacagtgaattggaagat
gtggcttcaaatacaaactcccaagatctcttgtttaattcttctaaacaaatgagtcac
ccatctgagaaccaggaagttgttctaagtgacaaggaattgatttcagatgatgaagaa
atggaaagtagcctggaaaaagataatcaagaggagaacgagatttcagatttagatgaa
gcagcatctgcatatgagggtgaagcaaacctttctgaagactcctcccagagtgatatt
ttgacaagtcagcagagagctaccatgaaagttaacctgataaagatccagcaggaaatg
gcccagctcgaagctgtgctagagcggcaggagaacctgccttcctgctgctccacttcc
ctcttagctgacccttgtgtccccaaggacctgctaaatccagaacaaaatgtatccaaa
acagaagtaattccatacctagaatctggagttacccttttctccaggagtcaccctgaa
tctgagctttctaaagagaaagccccagagccagctcatgtttcgatctctgccttgaaa
atatcccagtgtcaagctgcagaatattccaagagcccagctgctgctcatagcactgat
accgaggtggcaaaaaccgtgagcaagacaaagtcaaaatggacttcttcaaaaggaaga
gacaagaaaatatccatggtggtttcaggcttgacccacaaagaaataatgattgtgcaa
aagtttgccgaaaaataccacgtcaccttatctgatgtaataactgaggagactactcat
gtcattataaaaacagatgctgagtttgtgtgtgaacggacactgaaatattttatggga
attgccagaggaaaatggatagttagctatctctgggtgatccagtctattaaaaaaagg
aaacttttgaatgagcaagaatttgaagtcagaggagatgtcgtgaatggaagaaatcac
caaggtcccagacgatcaagagaatcccaggagaagatcttcaggggcctagaaatctgt
tgctgtgagcccttcagcagcatgcccagagatcaactggagaggatcctgcagatgtgt
ggggcgtctgtggtgaaggaactttcatcactcacctttggcacaggtactcagccagtt
gtggttctgcagccaagtgcctggacagaaaggaatgactaccttgatattgagaagatg
tgtgaggcacctgtggtgatgtgggactgggtgttggacagcatatccctctaccaacgc
cagaatctagaaacctacctgatcagtgcatgtcacccaacatcatga
DBGET
integrated database retrieval system
