Nomascus leucogenys (northern white-cheeked gibbon): 100580360
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Entry
100580360 CDS
T03265
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01524
Platinum drug resistance
nle03440
Homologous recombination
nle03460
Fanconi anemia pathway
nle04120
Ubiquitin mediated proteolysis
nle04151
PI3K-Akt signaling pathway
nle05206
MicroRNAs in cancer
nle05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100580360 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
100580360 (BRCA1)
03460 Fanconi anemia pathway
100580360 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
100580360 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100580360 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
100580360 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100580360 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
nle01009
]
100580360 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
nle04121
]
100580360 (BRCA1)
03036 Chromosome and associated proteins [BR:
nle03036
]
100580360 (BRCA1)
03400 DNA repair and recombination proteins [BR:
nle03400
]
100580360 (BRCA1)
Enzymes [BR:
nle01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
100580360 (BRCA1)
Protein phosphatases and associated proteins [BR:
nle01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
100580360 (BRCA1)
Ubiquitin system [BR:
nle04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
100580360 (BRCA1)
Multi subunit type E3
BRCC complex
100580360 (BRCA1)
Chromosome and associated proteins [BR:
nle03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
100580360 (BRCA1)
DNA repair and recombination proteins [BR:
nle03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
100580360 (BRCA1)
BRCA1-A complex
100580360 (BRCA1)
BRCA1-B complex
100580360 (BRCA1)
BRCA1-C complex
100580360 (BRCA1)
BRCA complex
100580360 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
100580360 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_2
zf-C3HC4_3
zf-RING_5
RING_XB3-XBAT31
BRCT_2
zf-RING_6
zf-Nse
zf-ANAPC11
zf-RING_10
zf-rbx1
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
100580360
NCBI-ProteinID:
NP_001295597
Ensembl:
ENSNLEG00000011944
UniProt:
A0A075VSA7
LinkDB
All DBs
AA seq
1863 aa
AA seq
DB search
MDLSAVRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLQYANSYNFAKKENNSPEHLKD
EVSIIQSMGYRNRAKRLLQSEPENPSLQETSFSVQLSNLGTVRTLRTKQQIQPQKKSVYI
ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHQQ
PSNNDLNTTEKRATERHPEKYQGSSVSNLHVELCGTNTHASSLQHENSSLLLTKDRMNVE
KAEFCNKSKQPGLARSQHNRWAGSKETCNDRQTPSTEKKVDLNADPLCERKEWNKQKLPC
SENPTDTEDVPWITLNSSIQKVNEWFSRSDELLSSDDSHDGGSESNAKVADVLDVLNEVD
EYSGSSEKIDLLASDPHESLICKSERVHSKSVESNIEDKIFGKTYRRKASLPNLSHVTEN
LIIGAFVTEPQIIQERPLTNKLKHKRRATSGLHPEDFIKKADLAVQKTPEMINQGTNQME
QNVQVMNITNSGHENKTIRDSIQNEKNPNPIESLEKESAFKAKTEPISSSISNMELELNI
HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEKKKKKYNQMPV
RHSRNLQLMEDKEPATGAKKSNKPNEQTSKRPDSDTFPELKLTNAPGSFTNCSNTSELKE
FVNPSLPREEKEEKLETVKVSNNAKDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ
ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKELIHGCSKDTRNDTEGFKYPLGHEVNHS
QETSIEMEESELDTQYLQNTFKVSKRQSFALFSNPGNPEEEYATFSAQSRSLKKRNPKVT
FECEQKEENQGKNKSNIKPVQTVNISAGFPVVCQKDKPVDYAKCSIKGGSRFCLSSQFRG
NKTGLITPNKHGLLQNPYHIPPLFPIKSIVKTKCKKNLLEENSEEHSMSPEREMGNENIP
STVSTISRNNIRESAFKEASSSNINEVGSSTNEVGSSINEVGSSDENIQAELGRNRGPKL
NAMLRLGVLQPEVYKQSLPRSNCKHPEIKRQEYEEVVQTVNTDFSPCVISDNLEQPMGSS
HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQRGELSRSPSPFTHTHLAQ
GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVSNIPSQSTRHSTVATECLSKNTEENL
LSLKNSLNDCSNQVILAKASQEHHLSEETKCSGSLFSSQCSELEDLTANTNTQDPFLIGS
SKQMRHHSESQGVGLSDKELVSGDEERGTGLEENNQEEQSVDSNLGEAASGYASETSVSE
DCSGLSSQSDILTTQQRDTMQDNLIKLQQEMAELEAVLEQHGSQPSHSYPSIISDSSALE
DLQNPEQSTSEKAVLTSQKSSAYPISQNPEGLFADKFEVSADSSTSKNKEPGVERSSPSK
CQSLDDRWYMHSCSGSLQNGNYPSQEELIKVVDVEEQQLEESGPHDLTEPSYLPRQDLEG
TPYLESGISLFSDDSESDPSADRAPESAHVGNIPSSTSALKVPQLKVAESAQSPAAAHTT
NTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYNFARKHHITLTNLI
TEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDV
VNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTL
GTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPH
SHY
NT seq
5592 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctgctgttcgcgttgaagaagtacaaaatgtcattaatgctatgcagaaa
atcttagagtgtcccatctgtctggagttgatcaaggaacctgtctccacaaagtgtgac
cacatattttgcaaattttgcatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctttatgtaagaatgatataaccaaaagaagcctacaagaaagtacgagatttagt
caacttgttgaagagctattgaaaatcatttgtgcttttcagcttgacacaggtttgcag
tatgcaaacagttataattttgcaaaaaaggaaaataactctcctgaacatctaaaagat
gaagtttctatcatccaaagtatgggctacagaaaccgtgccaaaagacttctacagagt
gaacctgaaaatccttccttgcaggaaaccagtttcagtgtccaactctctaaccttgga
actgtgagaactctgaggacaaagcagcagatacaacctcaaaagaagtctgtctacatt
gaattgggatctgattcttctgaagatacagttaataaggcaacttattgcagtgtggga
gatcaagaattgttacaaatcacccctcaaggaaccagggatgaaatcagtttggattct
gcaaaaaaggctgcttgtgaattttctgagacggatgtaacaaatactgaacatcaacaa
cccagtaataacgatttgaacaccactgagaagcgtgcaactgagaggcatccagaaaag
tatcagggtagttctgtttcaaacttgcatgtggagctatgtggcacaaatactcatgcc
agctcattacagcatgagaacagcagtttattactcactaaagacagaatgaatgtagaa
aaggctgaattctgtaataaaagcaaacagcctggcttagcaaggagccaacataacaga
tgggctggaagtaaggaaacatgtaatgataggcagactcccagcacagagaaaaaggta
gatctgaatgctgatcccctgtgtgagagaaaagaatggaataagcagaaactgccatgc
tcagagaatcctacagatactgaagatgttccttggataacactaaatagcagcattcag
aaagttaatgagtggttttccagaagtgatgaactgttaagttctgatgactcacatgat
ggggggtctgaatcaaatgccaaagtagctgatgtattggacgttctaaatgaggtagac
gaatattctggttcttcagagaaaatagacttactggccagtgatcctcatgagtcttta
atatgtaaaagtgaaagagttcactccaaatcagtagagagtaatattgaagacaaaata
tttgggaaaacctatcggaggaaggcaagcctccccaacttaagccatgtaactgaaaat
ctaattataggagcatttgttactgagccacagataatacaagagcgtcccctcacaaat
aaattaaagcataaaaggagagctacatcaggccttcatcctgaggattttatcaagaaa
gcagatttggcagttcaaaagactcctgaaatgataaatcagggaactaaccaaatggag
cagaatgttcaagtgatgaatattactaatagtggtcatgagaataaaacaatacgtgat
tctattcagaatgagaaaaatcctaacccaatagaatcactcgaaaaagaatctgctttc
aaagcgaaaactgaacctataagcagcagtataagcaatatggaactcgaattaaatatc
cacaattcaaaagcacctaaaaagaataggctgaggaggaagtcttctaccaggcatatt
catgcgcttgaactagtagtcagtagaaatctaagtccacctaattgtactgaattacaa
attgatagttgttctagcagtgaagagaaaaagaaaaaaaagtacaaccaaatgccagtc
aggcacagcagaaacctacaactcatggaagataaagaacctgcaactggagctaagaag
agtaacaagccaaatgaacagacaagtaaaagacctgacagcgatactttcccagagctg
aagttaacaaatgcacctggttctttcactaactgttcaaataccagtgaacttaaagaa
tttgtcaatcctagccttccaagagaagaaaaagaagagaaactagaaacagttaaagtg
tctaataatgccaaagaccccaaagatctcatgttaagtggagaaagggttttgcaaact
gaaagatctgtagagagtagcagtatttcattggtacctggtactgattatggcactcag
gaaagtatctcgttgctggaagttagcactctagggaaggcaaaaacagaaccaaataaa
tgtgtgagtcagtgtgcagcatttgaaaaccccaaggaactaattcatggttgttccaaa
gatactagaaatgacacagaaggctttaagtatccattgggacatgaagttaaccacagt
caggaaacaagcatagaaatggaagaaagtgaacttgatactcagtatttgcagaataca
ttcaaggtttcaaagcgccagtcatttgctctgttttcaaatccaggaaatccagaagag
gaatatgcaacattctctgcccagtctaggtccttaaagaaacgaaatccaaaagtcact
tttgaatgtgaacaaaaggaagaaaatcaaggaaagaataagtctaatatcaagcctgta
cagacagttaatatctctgcaggctttcctgtggtttgtcagaaagataagccagttgat
tatgccaaatgtagtatcaaaggaggctctaggttttgtctatcatctcagttcagaggc
aacaaaactggactcattactccaaataaacatggacttttacaaaacccatatcatata
ccaccactttttcccatcaagtcaattgttaaaactaaatgtaagaaaaacctgctagag
gaaaactctgaggaacattcaatgtcacctgaaagagaaatgggaaacgagaacattcca
agtacagtgagcacaattagccgtaataacattagagaaagtgcttttaaagaagccagc
tcaagcaatattaatgaagtaggttccagtactaatgaagtgggctccagtattaatgaa
gtaggttccagtgatgaaaacattcaggcagaactaggtagaaacagagggccaaaattg
aatgctatgcttagattaggggttttgcaacctgaggtctataaacaaagtcttcctaga
agtaattgtaagcatcctgaaataaaaaggcaagaatatgaagaagtagttcagactgtt
aatacagacttctctccatgtgtgatttcagataacctagaacagcctatgggaagtagt
catgcatctcaggtttgttctgagacacctgatgacctgttagatgatggtgaaataaag
gaagatactagttttgctgaaaatgacattaaggaaagttctgctgtttttagcaaaagc
gtccagagaggagagcttagcaggagtcctagccctttcacccacacacatttggctcag
ggttaccgaagaggggccaagaaattagagtcctcagaagagaacttatctagtgaggat
gaagagcttccctgcttccaacacttgttatttggtaaagtaagcaatataccttctcag
tctactaggcatagcaccgttgctaccgagtgtctgtctaagaacacagaggagaattta
ttatcactgaagaatagcttaaatgactgcagtaaccaggtaatattggcaaaggcatcc
caggaacatcaccttagtgaggaaacaaaatgttctggtagcttgttttcttcacagtgc
agtgaactggaagacttgaccgcaaatacaaacacccaggatcctttcttgattggttct
tccaaacaaatgaggcatcattctgaaagccagggagttggtctgagtgacaaggaattg
gtttcaggtgatgaagaaagaggaacaggcttggaagaaaataatcaagaagagcaaagc
gtggattcaaacttaggtgaagcagcatctgggtatgcgagtgaaacaagcgtctctgaa
gactgctcagggctatcctctcagagtgacattttaaccactcagcagagggataccatg
caagataacctgataaagctccagcaggaaatggctgaactagaagctgtgttagaacag
catgggagccagccttctcacagctacccttccatcataagtgactcttctgcccttgag
gacctgcaaaatccagaacaaagcacatcagaaaaagcagtattaacttcacagaaaagt
agtgcataccctataagccagaatccagaaggcctttttgctgacaagtttgaggtgtct
gcagatagttctaccagtaaaaataaagaaccaggagtggaaaggtcatccccttctaaa
tgccagtcattagatgataggtggtacatgcacagttgctctgggagtcttcagaatgga
aactacccatctcaagaggagctcattaaggttgttgatgtggaggagcaacagctggaa
gagtctgggccacacgatttgacggaaccatcttacttgccaaggcaagatctagaggga
accccttacttggaatctggaatcagcctcttctctgatgactctgaatctgatccttcg
gcagacagagccccagagtcagctcatgttggcaatataccatcttcaacctctgcattg
aaagtaccccagttgaaagttgctgaatctgcccagagtccagctgctgctcatactact
aatactgctgggtataatgcaatggaagaaagtgtgagcagggagaagccagaattgaca
gcttcaacagaaagggtcaacaaaagaatgtccatggtggtgtctggcctgaccccagaa
gaatttatgctcgtgtacaactttgccagaaaacaccacatcactttaactaatctaatt
actgaagagactactcatgttgttatgaaaacagatgctgagtttgtgtgtgaacggaca
ctgaaatatttcctaggaattgcgggaggaaaatgggtagttagctatttctgggtgacc
cagtctattaaagaaagaaaaatgctgaatgagcatgattttgaagtcagaggagatgtg
gtcaatggaagaaaccaccaaggtccaaagcgagcaagagaatcccaggacagaaagatc
ttcagagggctagaaatctgttgctatgggcccttcaccaacatgcccacagatcaactg
gagtggatggtacagctgtgtggtgcttctgtggtgaaggagctttcatcattcaccctt
ggcacaggtgtccacccaattgtggttgtgcagccagatgcctggacagaggacaatggc
ttccatgcaattgggcagatgtgtgaggcacctgtggtgacccgagagtgggtgttggac
agtgtagcactctaccagtgccaggagctggatacctacctgataccccagatcccccac
agccactactga
DBGET
integrated database retrieval system
