Nomascus leucogenys (northern white-cheeked gibbon): 100583956
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Entry
100583956 CDS
T03265
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2
KO
K07187
insulin receptor substrate 2
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04022
cGMP-PKG signaling pathway
nle04068
FoxO signaling pathway
nle04081
Hormone signaling
nle04140
Autophagy - animal
nle04152
AMPK signaling pathway
nle04211
Longevity regulating pathway
nle04213
Longevity regulating pathway - multiple species
nle04910
Insulin signaling pathway
nle04920
Adipocytokine signaling pathway
nle04923
Regulation of lipolysis in adipocytes
nle04930
Type II diabetes mellitus
nle04931
Insulin resistance
nle04932
Non-alcoholic fatty liver disease
nle04935
Growth hormone synthesis, secretion and action
nle05010
Alzheimer disease
nle05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
100583956 (IRS2)
04022 cGMP-PKG signaling pathway
100583956 (IRS2)
04152 AMPK signaling pathway
100583956 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
100583956 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100583956 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100583956 (IRS2)
04923 Regulation of lipolysis in adipocytes
100583956 (IRS2)
04920 Adipocytokine signaling pathway
100583956 (IRS2)
04935 Growth hormone synthesis, secretion and action
100583956 (IRS2)
09149 Aging
04211 Longevity regulating pathway
100583956 (IRS2)
04213 Longevity regulating pathway - multiple species
100583956 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100583956 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
100583956 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100583956 (IRS2)
04932 Non-alcoholic fatty liver disease
100583956 (IRS2)
04931 Insulin resistance
100583956 (IRS2)
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Gene cluster
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Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Motif
Other DBs
NCBI-GeneID:
100583956
NCBI-ProteinID:
XP_012362453
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All DBs
Position
5:complement(136045476..136076655)
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AA seq
1342 aa
AA seq
DB search
MASPPRHGPPGPANGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA
TAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE
YFAVAAENEQEQEGWYRALTDLVSEGRAAAGDAPPTAAPAASCSASLPGALGGSAGAAGA
EDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTL
QLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEF
RPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCR
VRTASEGDGGAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPA
GGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRP
SSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYG
YMTMDRPLSHCGRPYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLM
RATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAA
LAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAVPPAGPAGPAPTSAGGRTFPAS
GGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDF
FSAALHAGGEPLRGVPGCCYSSLPRSYKAPYTCGADSDQYVLMSSPVGRILEEERLEPQA
TPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGLGGGRPEGFLGQRGRAVRPTRLSLEGLP
SLPSMHEYPLPPEPKSPGEYINIDFGESGARLSPPAPPLLASAASSSSLLSASSPASSLG
SGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASPYPPLPPR
PSASPSSSLQPPPPPPPPGELYRLPPASAAATAQGPGAASLSSSDTGDNGDYTEMAFGVA
ATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADP
QGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEP
PTSPRQLQPALPAPPLAPQGRPWTPGQPGGLIGCPGSGGSPMRRETSAGFQNGLNYIAID
VREEPGLPPQPQPQPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPP
ANTYASIDFLSHHLKEATIVKE
NT seq
4029 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccgcggcacgggccgcccgggccggcgaacggagacggccccaacctc
aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag
aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgcgggcggcgacgaggcg
acggcgggcggggggtcggcgccgcagccgccgcggctcgagtactacgagagcgagaaa
aagtggcggagcaaggcaggcgcgccgaagcgggtgatcgcgctcgactgctgcctgaac
atcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaaggacgag
tacttcgccgtggccgccgagaacgagcaggagcaggagggctggtaccgcgcgctcacc
gacctggtcagcgagggccgcgcggccgccggagacgcgccccccaccgccgcgcccgcc
gcgtcctgcagcgcctccctgcccggcgccctgggcggctctgccggcgccgccggggcc
gaggacagctacgggctggtggcgcccgccacagccgcctaccgcgaggtgtggcaggtg
aacctgaagcccaagggtctgggccagagcaagaacctgacaggcgtgtaccgtctgtgc
ctgtcggcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgacgctg
cagctcatgaacatccgccgctgcggccactcggacagcttctttttcatcgaggtgggc
cgctcagccgtcacaggccccggcgagctgtggatgcaggcggacgactcggtggtggcg
cagaacatccacgagaccatcctggaggccatgaaggcgctcaaggagctcttcgagttc
cggccgcgcagcaagagccagtcgtcggggtcgtcggccacacaccccatcagcgtcccc
ggcgcgcgccgccaccaccacctggtcaacctgccccctagccagacaggcctggtgcgc
cgctcgcgcaccgacagcctggccgccaccccgccggcggccaagtgcagctcgtgccgg
gtgcgcaccgccagcgagggcgacggcggcgcggcgggggcggcggccgcgggcgccagg
ccggtgtcggtggctgggagccccctgagccccgggccggtgcgcgcgcccctgagccgc
tcgcacaccctgagcggcggctgcggcggccgcgggagcaaggtggcgctgctgccggca
gggggcgcgctgcagcacagccgctccatgtcaatgcccgtggcgcactcgccgcccgcc
gccaccagccccggctccctgtcgtccagcagcggccacggctcgggctcctacccgccg
ccgcccggcccgcacccgcccctgccgcatccgctgcaccacggccccggccagcggccc
tccagcggcagcgcctccgcctcgggctcccccagcgaccccggcttcatgtccctggac
gagtacggctccagcccaggcgacctgcgcgccttctgcagtcaccgaagcaacacgccc
gagtccatcgcggagacgcccccagcccgagacggcggcggcggcggtgagttctacggg
tacatgaccatggacaggcccctgagccactgtggccgcccctaccgccgggtctcgggg
gacgcggcccaggacctggaccgagggctgcgcaagaggacctactccctgaccacaccg
gcccggcagcggccggtgccccagccctcctctgcctcgctggatgagtacactctgatg
cgggccaccttctcgggcagcgcgggccgcctctgcccgtcctgccccgcgtcctctccc
aaggtggcctaccatccctacccagaggactacggagacatcgagatcggctcccacagg
agctccagcagcaacctgggcgcagacgacggctacatgcccatgacgcccggcgcggcc
ctcgcgggcagtgggagcggcagctgcaggagcgacgactacatgcccatgagccccgcc
agcgtgtccgcccccaagcagatcttgcaacccagggccgccgccgccgccgccgtgccc
cctgcggggcctgcggggccagcgcccacctctgcggggggcaggacattcccggcgagc
gggggtggctacaaggccagctcgcccgccgagagctcccccgaggacagtgggtacatg
cgcatgtggtgcggctccaagctgtccatggagcatgcagatggcaagctgctgcccaac
ggggactacctcaacgtgtcccccagcgacgcggtcaccacgggcaccccgcccgacttc
ttctccgcagccctgcacgccggcggggagccgctcaggggcgttcccggctgctgctac
agctccttgcctcgctcctacaaggccccgtacacctgtggcgcggacagcgaccagtac
gtgctcatgagctccccggtggggcgcatcctggaggaggagcggctggagcctcaggcc
acgccagggcccagccaggcggccagcgccttcggggccggccccacgcagccccctcac
cccgtagtgccttcgcccgtgcggcccagcggcggcctaggcggcggccgcccggagggc
ttcttgggccagcgcggccgggcggtgcggcccacgcgcctgtccctggaggggctgccc
agcctgcccagcatgcacgagtacccactgccgccggagcccaagagccccggcgagtac
atcaacatcgacttcggcgagtccggggcccgtctgtcgccgcccgcgcctcccctgctg
gcgtcggcggcctcgtcctcctcgctcttgtccgccagcagcccggcctcgtcgctgggc
tcaggcaccccgggcaccagcagcgacagccggcagcgctctccgctctccgactacatg
aacctcgacttcagctcccccaagtctcctaaaccgggcgccccaagcggccaccccgtg
ggctccttggacggcctcctgtcccccgaggcctccccgtatccgccgctgcccccgcgt
ccgtccgcgtccccgtcgtcgtccctgcagccgccgccaccgccgccgcccccgggggag
ctgtaccgcctgccccccgcctcggccgctgccactgcccagggcccgggcgccgcctca
ttgtcgtcctcggacaccggggacaatggtgactacaccgagatggcttttggtgtggcc
gccaccccgccgcaacccatcgcggctcccccgaagccagaagctgcccgcgtggccagc
ccgacgtcgggcgtgaagaggctgagcctcatggagcaggtgtcaggggtcgaggccttc
ctgcaggccagccagcccccggacccccaccgcggtgccaaggtcatccgcgcagacccg
caggggggccgccgccgccacagttccgagaccttctcctccaccacgacggtcaccccc
gtgtccccgtccttcgcccacaaccccaagcgccacaactcggcctccgtagaaaatgtc
tctctcaggaaaagcagcgagggcggtgtgggtgtcggccctggagggggcgacgagccg
cccacctccccccgacagttgcagccggcgctcccggcgccccctttggcaccgcagggc
cggccgtggaccccgggtcagcccgggggcttgatcggttgtcctgggagcggtggatcg
ccaatgcgcagagagacctctgccggcttccagaatggtctcaactacatcgccatcgac
gtgagggaggagcccgggctgccaccccagccgcagccgcagccgccgccgccgcttcct
cagccgggagacaagagctcctggggtcggacccgaagcctcgggggtctcatcagcgct
gtgggcgtcggcagcactggcggcgggtgcggggggccgggtcccggtgccctgccccct
gccaacacctacgccagcattgacttcttgtcccaccacttgaaggaggccaccatcgtg
aaagagtga
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