| Entry |
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| Symbol |
HSD17B4
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| Name |
(RefSeq) peroxisomal multifunctional enzyme type 2 isoform X1
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| KO |
| K12405 | (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.- 4.2.1.107 4.2.1.119] |
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| Organism |
nle Nomascus leucogenys (northern white-cheeked gibbon)
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| Pathway |
| nle01040 | Biosynthesis of unsaturated fatty acids |
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| Module |
| nle_M00104 | Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate |
| nle_M00862 | beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA |
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| Brite |
KEGG Orthology (KO) [BR:nle00001]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
100590035 (HSD17B4)
01040 Biosynthesis of unsaturated fatty acids
100590035 (HSD17B4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100590035 (HSD17B4)
Enzymes [BR:nle01000]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
100590035 (HSD17B4)
4.2.1.119 enoyl-CoA hydratase 2
100590035 (HSD17B4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
2:127446260..127534968
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| AA seq |
763 aa
MGSPLRFDGRVVVVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
RVHLRGSFQVTRAAWEHMRKQKYGRIIMTSSASGIYGNFGQANYGAAKLGLLGLANSLAI
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
KIDSEGGVSANHTSRATSIATSGFAGAIGQKLPPFSYVYTELEAIMYALGVGASIKDPKD
LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
AVAIPNRPPDAVLTDTTSLNQAVVTVFHPDIILGFPFYIFFSLLLILVAALYRLSGDWNP
LHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTL
QTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSDTSAKTPSEGGKLQSTLVFEEIGR
RLKDVGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDE
DFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL |
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| NT seq |
2292 nt +upstreamnt +downstreamnt
atgggctcaccgctgaggttcgacggccgggtggtagtggtcaccggcgctggggcagga
ttgggccgagcctatgccctggcttttgcagaaagaggagcgttagttgttgtgaatgat
ttgggaggggacttcaaaggagttggtaaaggctccttagctgctgataaggttgttgaa
gaaataagaaggagaggtggaaaagcagtggccaactatgattcagtggaagaaggagag
aaggttgtgaagacagccctggatgcttttggaagaatagatgttgtggtcaacaatgct
ggaattctgagggatcgttcctttgctaggataagtgatgaagactgggatataatccac
agagttcatttgcggggttcattccaagtgacacgggcagcatgggaacacatgaggaaa
cagaaatatggaaggattattatgacttcatcagcttcaggaatatatggcaactttggc
caggccaattatggtgctgcaaagttgggtcttctgggccttgcaaattctcttgcaatt
gaaggcaggaaaagcaacattcattgtaacaccattgctcctaatgcgggatcacggatg
actcagacagttatgcctgaagatctcgtggaagccctgaagccagagtatgtggcaccc
cttgtcctttggctttgtcacgagagttgtgaggagaatggtggcttgtttgaggttgga
gcaggatggattggaaaattacgctgggagcggactcttggagctattgtaagacaaaag
aatcacccaatgactcctgaggcagtcaaggctaactggaagaagatctgtgactttgag
aatgccagcaagcctcagagtatccaagaatcaactggcagtataattgaagttctgagt
aaaatagattcagaaggaggagtttcagcaaatcatactagtcgtgcaacgtctatagca
acatcaggatttgctggagctattggccagaaactccctccattttcttatgtttatacg
gaactggaagctattatgtatgcccttggagtgggagcatcaatcaaggatccaaaagat
ttgaaatttatttatgaaggaagttctgatttctcctgtttgcccaccttcggagttatc
ataggtcagaaatctatgatgggtggaggattagcagaaattcctggactttcaatcaac
tttgcaaaggttcttcatggagagcagtacttagagttatataaaccacttcccagagca
ggaaaattaaaatgtgaagcagttgttgctgatgtcctagataaaggatccggtgtagtg
attattatggatgtgtattcttattctgagaaggaacttatatgccacaatcagttctct
ctctttcttgttggctctggaggctttggtggaaaacggacatcagacaaagtcaaggta
gctgtagccatacctaatagacctcctgatgctgtacttacggataccacctctcttaat
caggcagtagtaacagtgtttcacccagatataattcttggcttccccttctacattttt
ttttccctcctactgattttagtggctgctttgtaccgcctcagtggagactggaatccc
ttacacatcgatcctaactttgctagtctagcaggttttgacaagcccatattacatgga
ttatgtacattcggattttctgccaggcgtgttttacagcagtttgcagataatgatgtg
tcaagattcaaggcaattaaggctcgttttgcaaagccagtatatccaggacaaactcta
caaactgagatgtggaaggaaggaaacagaattcattttcaaaccaaggtccaagaaact
ggagacattgtcatttcaaatgcatatgtggatcttgcaccaacatctgatacttcagct
aagacaccctctgagggcgggaagcttcagagtactctcgtatttgaggaaataggacgc
cgcctaaaggatgttgggcctgaggtggtgaagaaagtaaatgctgtatttgagtggcat
ataaccaaaggcggaaatattggggctaagtggactattgacctgaaaagtggttctgga
aaagtgtaccaaggccctgcaaaaggagctgctgatacaacaatcatactttcagatgaa
gatttcatggaggtggtcctgggcaagcttgaccctcagaaggcattctttagtggcaga
ctgaaggccagagggaacatcatgctgagccagaaacttcagatgattcttaaagactat
gccaagctctga |
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