Nomascus leucogenys (northern white-cheeked gibbon): 100591270
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Entry
100591270 CDS
T03265
Symbol
PIK3R3
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
KO
K02649
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01521
EGFR tyrosine kinase inhibitor resistance
nle01522
Endocrine resistance
nle01524
Platinum drug resistance
nle04012
ErbB signaling pathway
nle04014
Ras signaling pathway
nle04015
Rap1 signaling pathway
nle04024
cAMP signaling pathway
nle04062
Chemokine signaling pathway
nle04066
HIF-1 signaling pathway
nle04068
FoxO signaling pathway
nle04070
Phosphatidylinositol signaling system
nle04071
Sphingolipid signaling pathway
nle04072
Phospholipase D signaling pathway
nle04081
Hormone signaling
nle04140
Autophagy - animal
nle04145
Phagocytosis
nle04150
mTOR signaling pathway
nle04151
PI3K-Akt signaling pathway
nle04152
AMPK signaling pathway
nle04210
Apoptosis
nle04211
Longevity regulating pathway
nle04213
Longevity regulating pathway - multiple species
nle04218
Cellular senescence
nle04360
Axon guidance
nle04370
VEGF signaling pathway
nle04380
Osteoclast differentiation
nle04510
Focal adhesion
nle04517
IgSF CAM signaling
nle04518
Integrin signaling
nle04550
Signaling pathways regulating pluripotency of stem cells
nle04611
Platelet activation
nle04613
Neutrophil extracellular trap formation
nle04620
Toll-like receptor signaling pathway
nle04625
C-type lectin receptor signaling pathway
nle04630
JAK-STAT signaling pathway
nle04650
Natural killer cell mediated cytotoxicity
nle04660
T cell receptor signaling pathway
nle04662
B cell receptor signaling pathway
nle04664
Fc epsilon RI signaling pathway
nle04666
Fc gamma R-mediated phagosome formation
nle04668
TNF signaling pathway
nle04670
Leukocyte transendothelial migration
nle04722
Neurotrophin signaling pathway
nle04725
Cholinergic synapse
nle04750
Inflammatory mediator regulation of TRP channels
nle04810
Regulation of actin cytoskeleton
nle04910
Insulin signaling pathway
nle04914
Progesterone-mediated oocyte maturation
nle04915
Estrogen signaling pathway
nle04917
Prolactin signaling pathway
nle04919
Thyroid hormone signaling pathway
nle04923
Regulation of lipolysis in adipocytes
nle04926
Relaxin signaling pathway
nle04929
GnRH secretion
nle04930
Type II diabetes mellitus
nle04931
Insulin resistance
nle04932
Non-alcoholic fatty liver disease
nle04933
AGE-RAGE signaling pathway in diabetic complications
nle04935
Growth hormone synthesis, secretion and action
nle04960
Aldosterone-regulated sodium reabsorption
nle04973
Carbohydrate digestion and absorption
nle05010
Alzheimer disease
nle05017
Spinocerebellar ataxia
nle05020
Prion disease
nle05100
Bacterial invasion of epithelial cells
nle05135
Yersinia infection
nle05142
Chagas disease
nle05146
Amoebiasis
nle05160
Hepatitis C
nle05161
Hepatitis B
nle05162
Measles
nle05163
Human cytomegalovirus infection
nle05164
Influenza A
nle05165
Human papillomavirus infection
nle05166
Human T-cell leukemia virus 1 infection
nle05167
Kaposi sarcoma-associated herpesvirus infection
nle05168
Herpes simplex virus 1 infection
nle05169
Epstein-Barr virus infection
nle05170
Human immunodeficiency virus 1 infection
nle05171
Coronavirus disease
nle05200
Pathways in cancer
nle05203
Viral carcinogenesis
nle05205
Proteoglycans in cancer
nle05206
MicroRNAs in cancer
nle05207
Chemical carcinogenesis - receptor activation
nle05208
Chemical carcinogenesis - reactive oxygen species
nle05210
Colorectal cancer
nle05211
Renal cell carcinoma
nle05212
Pancreatic cancer
nle05213
Endometrial cancer
nle05214
Glioma
nle05215
Prostate cancer
nle05218
Melanoma
nle05220
Chronic myeloid leukemia
nle05221
Acute myeloid leukemia
nle05222
Small cell lung cancer
nle05223
Non-small cell lung cancer
nle05224
Breast cancer
nle05225
Hepatocellular carcinoma
nle05226
Gastric cancer
nle05230
Central carbon metabolism in cancer
nle05231
Choline metabolism in cancer
nle05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
nle05415
Diabetic cardiomyopathy
nle05417
Lipid and atherosclerosis
nle05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100591270 (PIK3R3)
04014 Ras signaling pathway
100591270 (PIK3R3)
04015 Rap1 signaling pathway
100591270 (PIK3R3)
04370 VEGF signaling pathway
100591270 (PIK3R3)
04630 JAK-STAT signaling pathway
100591270 (PIK3R3)
04668 TNF signaling pathway
100591270 (PIK3R3)
04066 HIF-1 signaling pathway
100591270 (PIK3R3)
04068 FoxO signaling pathway
100591270 (PIK3R3)
04070 Phosphatidylinositol signaling system
100591270 (PIK3R3)
04072 Phospholipase D signaling pathway
100591270 (PIK3R3)
04071 Sphingolipid signaling pathway
100591270 (PIK3R3)
04024 cAMP signaling pathway
100591270 (PIK3R3)
04151 PI3K-Akt signaling pathway
100591270 (PIK3R3)
04152 AMPK signaling pathway
100591270 (PIK3R3)
04150 mTOR signaling pathway
100591270 (PIK3R3)
09133 Signaling molecules and interaction
04081 Hormone signaling
100591270 (PIK3R3)
04517 IgSF CAM signaling
100591270 (PIK3R3)
04518 Integrin signaling
100591270 (PIK3R3)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagocytosis
100591270 (PIK3R3)
04140 Autophagy - animal
100591270 (PIK3R3)
09143 Cell growth and death
04210 Apoptosis
100591270 (PIK3R3)
04218 Cellular senescence
100591270 (PIK3R3)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100591270 (PIK3R3)
04550 Signaling pathways regulating pluripotency of stem cells
100591270 (PIK3R3)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100591270 (PIK3R3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100591270 (PIK3R3)
04613 Neutrophil extracellular trap formation
100591270 (PIK3R3)
04620 Toll-like receptor signaling pathway
100591270 (PIK3R3)
04625 C-type lectin receptor signaling pathway
100591270 (PIK3R3)
04650 Natural killer cell mediated cytotoxicity
100591270 (PIK3R3)
04660 T cell receptor signaling pathway
100591270 (PIK3R3)
04662 B cell receptor signaling pathway
100591270 (PIK3R3)
04664 Fc epsilon RI signaling pathway
100591270 (PIK3R3)
04666 Fc gamma R-mediated phagosome formation
100591270 (PIK3R3)
04670 Leukocyte transendothelial migration
100591270 (PIK3R3)
04062 Chemokine signaling pathway
100591270 (PIK3R3)
09152 Endocrine system
04910 Insulin signaling pathway
100591270 (PIK3R3)
04923 Regulation of lipolysis in adipocytes
100591270 (PIK3R3)
04929 GnRH secretion
100591270 (PIK3R3)
04915 Estrogen signaling pathway
100591270 (PIK3R3)
04914 Progesterone-mediated oocyte maturation
100591270 (PIK3R3)
04917 Prolactin signaling pathway
100591270 (PIK3R3)
04926 Relaxin signaling pathway
100591270 (PIK3R3)
04935 Growth hormone synthesis, secretion and action
100591270 (PIK3R3)
04919 Thyroid hormone signaling pathway
100591270 (PIK3R3)
09154 Digestive system
04973 Carbohydrate digestion and absorption
100591270 (PIK3R3)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
100591270 (PIK3R3)
09156 Nervous system
04725 Cholinergic synapse
100591270 (PIK3R3)
04722 Neurotrophin signaling pathway
100591270 (PIK3R3)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100591270 (PIK3R3)
09158 Development and regeneration
04360 Axon guidance
100591270 (PIK3R3)
04380 Osteoclast differentiation
100591270 (PIK3R3)
09149 Aging
04211 Longevity regulating pathway
100591270 (PIK3R3)
04213 Longevity regulating pathway - multiple species
100591270 (PIK3R3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100591270 (PIK3R3)
05206 MicroRNAs in cancer
100591270 (PIK3R3)
05205 Proteoglycans in cancer
100591270 (PIK3R3)
05207 Chemical carcinogenesis - receptor activation
100591270 (PIK3R3)
05208 Chemical carcinogenesis - reactive oxygen species
100591270 (PIK3R3)
05203 Viral carcinogenesis
100591270 (PIK3R3)
05230 Central carbon metabolism in cancer
100591270 (PIK3R3)
05231 Choline metabolism in cancer
100591270 (PIK3R3)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100591270 (PIK3R3)
09162 Cancer: specific types
05210 Colorectal cancer
100591270 (PIK3R3)
05212 Pancreatic cancer
100591270 (PIK3R3)
05225 Hepatocellular carcinoma
100591270 (PIK3R3)
05226 Gastric cancer
100591270 (PIK3R3)
05214 Glioma
100591270 (PIK3R3)
05221 Acute myeloid leukemia
100591270 (PIK3R3)
05220 Chronic myeloid leukemia
100591270 (PIK3R3)
05218 Melanoma
100591270 (PIK3R3)
05211 Renal cell carcinoma
100591270 (PIK3R3)
05215 Prostate cancer
100591270 (PIK3R3)
05213 Endometrial cancer
100591270 (PIK3R3)
05224 Breast cancer
100591270 (PIK3R3)
05222 Small cell lung cancer
100591270 (PIK3R3)
05223 Non-small cell lung cancer
100591270 (PIK3R3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100591270 (PIK3R3)
05170 Human immunodeficiency virus 1 infection
100591270 (PIK3R3)
05161 Hepatitis B
100591270 (PIK3R3)
05160 Hepatitis C
100591270 (PIK3R3)
05171 Coronavirus disease
100591270 (PIK3R3)
05164 Influenza A
100591270 (PIK3R3)
05162 Measles
100591270 (PIK3R3)
05168 Herpes simplex virus 1 infection
100591270 (PIK3R3)
05163 Human cytomegalovirus infection
100591270 (PIK3R3)
05167 Kaposi sarcoma-associated herpesvirus infection
100591270 (PIK3R3)
05169 Epstein-Barr virus infection
100591270 (PIK3R3)
05165 Human papillomavirus infection
100591270 (PIK3R3)
09171 Infectious disease: bacterial
05135 Yersinia infection
100591270 (PIK3R3)
05100 Bacterial invasion of epithelial cells
100591270 (PIK3R3)
09174 Infectious disease: parasitic
05146 Amoebiasis
100591270 (PIK3R3)
05142 Chagas disease
100591270 (PIK3R3)
09164 Neurodegenerative disease
05010 Alzheimer disease
100591270 (PIK3R3)
05017 Spinocerebellar ataxia
100591270 (PIK3R3)
05020 Prion disease
100591270 (PIK3R3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100591270 (PIK3R3)
05418 Fluid shear stress and atherosclerosis
100591270 (PIK3R3)
05415 Diabetic cardiomyopathy
100591270 (PIK3R3)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100591270 (PIK3R3)
04932 Non-alcoholic fatty liver disease
100591270 (PIK3R3)
04931 Insulin resistance
100591270 (PIK3R3)
04933 AGE-RAGE signaling pathway in diabetic complications
100591270 (PIK3R3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100591270 (PIK3R3)
01524 Platinum drug resistance
100591270 (PIK3R3)
01522 Endocrine resistance
100591270 (PIK3R3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
nle04131
]
100591270 (PIK3R3)
Membrane trafficking [BR:
nle04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
100591270 (PIK3R3)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3K_P85_iSH2
SH2
SH2_1
DicA_C
ODF2_C
Exonuc_VII_L
Motif
Other DBs
NCBI-GeneID:
100591270
NCBI-ProteinID:
XP_003259085
Ensembl:
ENSNLEG00000016649
UniProt:
G1S3Y6
LinkDB
All DBs
Position
12:complement(14909415..15003248)
Genome browser
AA seq
461 aa
AA seq
DB search
MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
KYGFSDPLTFNSVVELITHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSIKP
DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgtacaatacggtgtggagtatggaccgcgatgacgcagactggagggaggtgatgatg
ccctattcgacagaactgatattttatattgaaatggatcctccagctcttccaccaaag
ccgcctaagccaatgacttcagcagttccaaatggaatgaaggacagttctgtttctctt
caggatgcagaatggtactggggggatatttcaagggaggaggtaaatgacaaattgcgg
gatatgccagatgggaccttcttggtccgagatgcctcaacaaaaatgcagggagattat
actttgactttgcggaagggaggcaataataagctaataaagatctatcaccgggatggt
aaatatggcttttctgatcctctgacatttaattccgtggtggagctcattacccactat
caccatgaatctcttgctcagtacaatcccaaacttgatgtgaagctgatgtacccagtg
tccagataccaacaggatcagttggtaaaagaagataatattgatgcagtaggtaaaaaa
ctgcaagaataccactctcagtatcaggagaagagtaaagagtatgataggctgtatgaa
gaatatactagaacatcccaggaaatacagatgaagaggactgcaatagaagcttttaat
gaaacaattaaaatatttgaagagcagtgtcacacacaagaacaacatagcaaagaatat
attgagcgatttcgcagagaggggaatgaaaaggagattgaacgaattatgatgaattat
gataaattgaaatcacgtctgggcgagattcatgatagcaaaatgcgtctagagcaggat
ttgaagaaacaagctttggacaaccgagaaatagataaaaaaatgaatagtatcaaacct
gacctgatccagctgcgaaagatccgagatcaacaccttgtatggctcaatcacaaagga
gtgagacagaaacgcctgaatgtctggctgggaattaagaatgaggatgctgatgagaac
tattttatcaatgaggaagatgaaaacctgccccattatgatgagaaaacctggtttgtt
gaggatatcaatcgagtacaagcagaagacttgctttatgggaaacctgatggtgcattc
ttaattcgtgagagtagcaaaaaaggatgctatgcttgctctgtggtggccgatggggaa
gtgaagcactgtgtgatctacagtactgctcggggctatggctttgcagagccctacaac
ctgtacagctctctgaaggagctagtgctccattaccagcagacatccttggttcagcac
aacgactccctcaacgtcaggcttgcctaccctgttcatgcacagatgccctcgctttgc
agataa
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integrated database retrieval system
