KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100594967
Entry
100594967         CDS       T03265                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01522  Endocrine resistance
nle04110  Cell cycle
nle04115  p53 signaling pathway
nle04151  PI3K-Akt signaling pathway
nle04218  Cellular senescence
nle04530  Tight junction
nle04660  T cell receptor signaling pathway
nle04933  AGE-RAGE signaling pathway in diabetic complications
nle04934  Cushing syndrome
nle05160  Hepatitis C
nle05162  Measles
nle05163  Human cytomegalovirus infection
nle05164  Influenza A
nle05165  Human papillomavirus infection
nle05166  Human T-cell leukemia virus 1 infection
nle05167  Kaposi sarcoma-associated herpesvirus infection
nle05169  Epstein-Barr virus infection
nle05200  Pathways in cancer
nle05203  Viral carcinogenesis
nle05212  Pancreatic cancer
nle05214  Glioma
nle05218  Melanoma
nle05219  Bladder cancer
nle05220  Chronic myeloid leukemia
nle05222  Small cell lung cancer
nle05223  Non-small cell lung cancer
nle05224  Breast cancer
nle05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:nle00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    100594967 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100594967 (CDK4)
   04115 p53 signaling pathway
    100594967 (CDK4)
   04218 Cellular senescence
    100594967 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    100594967 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    100594967 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100594967 (CDK4)
   05203 Viral carcinogenesis
    100594967 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100594967 (CDK4)
   05225 Hepatocellular carcinoma
    100594967 (CDK4)
   05214 Glioma
    100594967 (CDK4)
   05220 Chronic myeloid leukemia
    100594967 (CDK4)
   05218 Melanoma
    100594967 (CDK4)
   05219 Bladder cancer
    100594967 (CDK4)
   05224 Breast cancer
    100594967 (CDK4)
   05222 Small cell lung cancer
    100594967 (CDK4)
   05223 Non-small cell lung cancer
    100594967 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100594967 (CDK4)
   05160 Hepatitis C
    100594967 (CDK4)
   05164 Influenza A
    100594967 (CDK4)
   05162 Measles
    100594967 (CDK4)
   05163 Human cytomegalovirus infection
    100594967 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100594967 (CDK4)
   05169 Epstein-Barr virus infection
    100594967 (CDK4)
   05165 Human papillomavirus infection
    100594967 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100594967 (CDK4)
   04934 Cushing syndrome
    100594967 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100594967 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:nle01001]
    100594967 (CDK4)
Enzymes [BR:nle01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     100594967 (CDK4)
Protein kinases [BR:nle01001]
 Serine/threonine kinases: CMGC group
  CDK family
   100594967 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 100594967
NCBI-ProteinID: XP_003252803
Ensembl: ENSNLEG00000017205
UniProt: G1S5W7
LinkDB
Position
11:53522661..53528970
AA seq 303 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacctctcgatatgagccagtcgctgaaattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtcccc
aatggaggaggagctggaggaggccttcccatcagcacagttcgtgaggtggccttactg
aggcgactggaggcttttgagcatcccaatgttgtccggctgatggacgtctgtgccaca
tcccgaactgaccgggagatcaaggtaaccctggtgtttgagcatgtagaccaggaccta
aggacatatctggacaaggcgcccccaccaggcttgccagccgaaaccatcaaggatctg
atgcgccagtttctaagaggcctagatttccttcatgccaattgcatcgttcaccgagat
ctgaagccagagaacattctggtgacaagtggtggaacagtcaagctggctgactttggc
ctagccagaatctacagctaccagatggcacttacacccgtggttgttacactctggtac
cgagctcccgaagttcttctgcagtccacatatgcaacacctgtggacatgtggagtgtt
ggctgcatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagcc
gaccagttgggcaaaatctttgacctgattgggctgcctccagaagatgactggcctcga
gatgtatccctgccccgtggagcctttccccccagagggccccgcccagtgcagtcggtg
gtacctgagatggaggagtcgggagcacagctgctgctggaaatgctgacttttaacccg
cacaagcgaatctctgcctttcgagctctgcagcactcttatctacataaggatgaaggt
aatccggagtga

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