KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100597186
Entry
100597186         CDS       T03265                                 
Symbol
MMP2
Name
(RefSeq) 72 kDa type IV collagenase isoform X1
  KO
K01398  matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle01522  Endocrine resistance
nle04670  Leukocyte transendothelial migration
nle04912  GnRH signaling pathway
nle04915  Estrogen signaling pathway
nle04926  Relaxin signaling pathway
nle04933  AGE-RAGE signaling pathway in diabetic complications
nle05200  Pathways in cancer
nle05205  Proteoglycans in cancer
nle05219  Bladder cancer
nle05415  Diabetic cardiomyopathy
nle05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nle00001]
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    100597186 (MMP2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100597186 (MMP2)
   04915 Estrogen signaling pathway
    100597186 (MMP2)
   04926 Relaxin signaling pathway
    100597186 (MMP2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100597186 (MMP2)
   05205 Proteoglycans in cancer
    100597186 (MMP2)
  09162 Cancer: specific types
   05219 Bladder cancer
    100597186 (MMP2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100597186 (MMP2)
   05415 Diabetic cardiomyopathy
    100597186 (MMP2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100597186 (MMP2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100597186 (MMP2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:nle01002]
    100597186 (MMP2)
Enzymes [BR:nle01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.24  gelatinase A
     100597186 (MMP2)
Peptidases and inhibitors [BR:nle01002]
 Metallo peptidases
  Family M10
   100597186 (MMP2)
SSDB
Motif
Pfam: Peptidase_M10 fn2 Hemopexin PG_binding_1 Reprolysin_3 Reprolysin_5 Peptidase_M66
Other DBs
NCBI-GeneID: 100597186
NCBI-ProteinID: XP_003263105
Ensembl: ENSNLEG00000001210
LinkDB
Position
2:complement(64758912..64874877)
AA seq 660 aa
MEALMARGALTGALRALCLLGCLLSQAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC
PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
KNQITYRIVGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT
SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGISQ
IRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY
WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDP
GFPKLIADAWNAIPDNLDAVVDLQGSGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
NT seq 1983 nt   +upstreamnt  +downstreamnt
atggaggcgctaatggcccggggcgcgctcactggtgccctgagggcgctctgcctcctg
ggctgcctgctgagccaagccgccgccgcgccgtcgcccatcatcaagttccccggcgat
gtagcccccaaaacggacaaagagttggcagtgcaatacctgaacaccttttatggctgc
cccaaggaaagctgcaacctgtttgtgctgaaggacacactaaagaagatgcagaagttc
tttggactgcctcagacaggtgatcttgaccagaataccatcgagaccatgcggaagcca
cgctgcggcaacccagatgtggccaactacaacttcttccctcgcaagcccaagtgggac
aagaaccagatcacatacaggatcgttggctacacgcctgatctggacccagagacggtg
gatgatgcctttgctcgtgccttccaagtctggagtgatgtgaccccactgcggttttct
cgaatccatgatggagaggcagacatcatgatcaactttggccgctgggagcatggcgat
ggatacccctttgatggtaaggacggactcctggctcatgccttcgccccaggcactggt
gttgggggagactcccactttgatgatgatgagctatggaccttgggagaaggccaagtg
gtccgtgtgaagtacgggaacgccgatggggagtactgcaagttccccttcttgttcaat
ggcaaggagtacaacagctgcactgacactggccgcagcgatggcttcctctggtgctcc
accacctacaactttgagaaggatggcaagtacggcttctgtccccacgaagccctgttc
accatgggtggcaacgctgaaggacagccctgcaagttcccattccgcttccagggcaca
tcctatgacagctgcaccactgagggccgcacggatggctaccgctggtgcggcaccact
gaggactacgaccgcgacaagaagtatggcttctgccccgaaaccgccatgtccactgtt
ggtgggaactcagaaggtgccccctgtgtcttccccttcactttcctgggcaacaaatat
gagagctgcaccagcgccggccgcagtgatggaaagatgtggtgtgcgaccacagccaac
tacgatgacgaccgcaagtggggcttctgccctgaccaagggtacagcctgttcctcgtg
gcagcccacgagtttggccacgccatggggctggagcactcccaggaccctggggccctg
atggcgcccatttacacctacaccaagaacttccgtctgtcccaggatgacatcaagggc
attcaggagctctatggggcctctcctgacattgaccttggcaccggccccacccccaca
ctgggccctgtcactcctgagatctgcaaacaggacattgtctttgatggcatctctcag
atccgtggtgagatcttcttcttcaaggaccggttcatttggcggaccgtgacgccacgt
gacaagcccatggggcccctgctggtggccacattctggcctgagctcccggaaaagatt
gatgcggtatacgaggccccacaggaggagaaggctgtgttctttgcagggaatgaatac
tggatctactcagccagcaccctggagcgagggtaccccaagccactgaccagcctggga
ctgccccctgatgtccagcgagtggatgctgcctttaactggagcaaaaacaagaagaca
tacatctttgctggagacaaattctggagatacaatgaggtgaagaagaaaatggatcct
ggcttccccaagctcatcgcagatgcctggaatgccatccccgataacctggatgccgtc
gtggacctgcagggcagcggtcacagctacttcttcaagggtgcttattacctgaagctg
gagaaccaaagtctgaagagcgtgaagttcggaagcatcaaatccgactggctaggctgc
tga

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