Nomascus leucogenys (northern white-cheeked gibbon): 100597701
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Entry
100597701 CDS
T03265
Symbol
FASN
Name
(RefSeq) fatty acid synthase
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00061
Fatty acid biosynthesis
nle01100
Metabolic pathways
nle01212
Fatty acid metabolism
nle04152
AMPK signaling pathway
nle04910
Insulin signaling pathway
nle04936
Alcoholic liver disease
Module
nle_M00082
Fatty acid biosynthesis, initiation
nle_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100597701 (FASN)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100597701 (FASN)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100597701 (FASN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
nle01004
]
100597701 (FASN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
nle04147
]
100597701 (FASN)
Enzymes [BR:
nle01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
100597701 (FASN)
Lipid biosynthesis proteins [BR:
nle01004
]
Fatty acid synthase
Animal type
100597701 (FASN)
Exosome [BR:
nle04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
100597701 (FASN)
Exosomal proteins of breast milk
100597701 (FASN)
Exosomal proteins of colorectal cancer cells
100597701 (FASN)
Exosomal proteins of bladder cancer cells
100597701 (FASN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
Thioesterase
KR
KAsynt_C_assoc
Ketoacyl-synt_C
FAS_pseudo-KR
ADH_zinc_N_2
ADH_zinc_N
PKS_DH_N
Methyltransf_12
PP-binding
adh_short
Methyltransf_31
Methyltransf_11
Methyltransf_23
PS-DH
DUF7080
Thiolase_N
Methyltransf_25
adh_short_C2
YjeF_N
AlaDh_PNT_C
ACP_syn_III
Motif
Other DBs
NCBI-GeneID:
100597701
NCBI-ProteinID:
XP_030683427
Ensembl:
ENSNLEG00000014036
LinkDB
All DBs
Position
14:84675457..84695219
Genome browser
AA seq
2510 aa
AA seq
DB search
MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF
DASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEAL
SRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQC
PAAIVGGINILLKPNTSVQFLRLGMLSPEGTCKAFDAAGDGYCRSEGVVAVLLTKKSLAR
RVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVG
DPQELNGITRALCATRQEPLLIGSTKSNMGHPEPVSGLAALAKVLLSLEHGLWAPNLHFH
SPSPEIPALSDGRLQVVAQPLPVRGGNVGINSFGFGGSNVHVILRPNTQPPPAPAPHATL
PRLLRASGRTPEAVQKLLEQGLQHSQDLAFLSMLNDIAAVPTTAMPFRGYAVLGGERGGP
EVQQVPAGKRPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLS
TDEGTFDDIVHSFVSLTAIQIGLIDLLSCVGLRPDGIIGHSLGEVACGYADGCLSQEEAV
LAAYWRGQCIKEAHLPLGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFE
FVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQALKKVIREPKPRSARWLSTSIPEA
QWHGSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCT
IIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSL
TWDVPAAEDFPNGSGSPSAAVYNIDTSSESPDHYLVDHTLDGRVIFPATGYLSIVWKTLA
RALGLAIEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLIVSGKVYQ
WDDPDPRLFDLPESPTPNPAEPLFLAQAEVYRELRLRGYDYGPHFQGILEASLEGDSGKL
LWKDNWVSFMDTMLQMSILGLAKHGLHLPTRITAIHIDPATHRQKLYTLQDKAQVADVVV
SRWLSVTVAGGVHISRLHTESAPRRQQEQHVPILEKFCFTPHMEEGCLSERTALQEELQL
CKGLAQALQTKVTQQGLKMAVPGLDGAQVPRDPSQQELPRLLWAACRLQLNGNLQLELAQ
VLAQERPKLPEDPLLSGLLDSPALKACLDTAFENMPSPKMKVVEVLAGHGHLYSRIPGLL
SPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA
ALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDTMAFLTSAEPQYGQGILSQDAWESL
FSRVSLRLVGLKKSFYGSTLFLCRRPSPQGSPIFLPVDDTSFRWVESLKGILADEDSSQP
VWLKAINCSTSGVVGLVNCLRQELGGHRLRCVLLSNLSSTSRVPEVDPGSAELQKVLQGD
LVMNVYRDGAWGAFRHFLLEEDKPEELTAHAFVTTLTRGDLSSIRWVCSSLRHAQPTHPG
AQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAE
GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETVLIHSGSGGV
GQAAIAIALSLGCRVFTTVGSAEKRVYLQARFPQLDSTSFANSRDTSFEQHVLRHTGGKG
VDLVLNSLAEEKLQASVRCLAMHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFF
NGSSADWREVSALVQAGIRDGVVRPLKCTVFPGAQVEDAFRYMAQGKHIGKVVVQVLAEE
PEAVLKGAKPKLMSAISKTFCPAHKSYIITGGLGGFGLELAQWLIQRGVQKLVLTSRSGI
RTGYQAKQVRRWRRQGVQVQVSTSNVSSLEGARGLIAEAAQLGPVGGVFNLAVVLRDALL
ENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSSGRGNAGQSNYGFANSA
MERICEKRRHEGLPGLAVQWGAIGDVGLLADMSINDTVIGGTLPQRMASCLEVLDLFLNQ
PHMVLSSFVLAEKAAAYRDRDSQQDVVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSVE
VRQTLERELNLVLSVREVRQLTLRKLQELSSKADAANELASPTPKEDGLAQQQTQLNLRS
LLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLDS
IHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGSP
TYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNKVLEALLPLKGLEERVAAAV
DLIIKSHQGLDRQELSFAALSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGAD
YNLSQVCDGKVSIHVIEGDHRTLLEGSGLESIVSIIHSSLAEPRVSVREG
NT seq
7533 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggtggtgattgccggcatgtccgggaagctgccggagtcagagaacttgcag
gagttctgggacaacctcatcggcggtgtggacatggtcacggacgacgaccgtcgctgg
aaggcggggctctacggcctgccccggcggtccggcaagctgaaggacctgtctaggttt
gatgcctccttcttcggagtccaccccaagcaggcacacacgatggaccctcagctgcgg
ctgctgctggaggtcacctatgaagccatcgtggacggaggcatcaacccagattcactt
cgagggacacacactggcgtctgggtgggcgtgagcggctctgagacctcggaggccctg
agccgagaccctgaaacactcgtgggctacagcatggtgggctgccagcgagccatgatg
gccaaccggctctccttcttcttcgacttcagagggcccagcatcgccctggacacggcc
tgctcctccagcctgatggccctgcagaacgcctaccaggccatccacagcgggcagtgc
cctgccgccatcgtggggggcatcaacatcctgctaaagcccaacacctccgtgcagttc
ttgaggctggggatgctcagccccgagggcacctgcaaggcctttgatgcagcaggggat
gggtactgccgctcggagggtgtggtggccgtcctgctgaccaagaagtccctggcccgg
cgggtgtatgccaccatcctgaacgccggcaccaatacagatggcttcaaggagcaaggc
gtgaccttcccctcaggggatatccaggagcagctcatccgttcgttgtaccagtcagct
ggagtggcccctgagtcgtttgagtacatcgaagcccacggcacaggcaccaaggtgggc
gacccccaggagctgaatggcatcacccgagccctgtgcgccacccgccaggagccgctg
ctcatcggctccaccaagtccaacatggggcacccggagccagtctcggggctggcagcc
ctggccaaggtgttgctgtccctagagcacgggctctgggcccccaacctgcacttccac
agccccagccctgagatcccagcgctgtcggatgggcggctgcaagtggtggcccagccc
ctgcccgtccgtggcggcaacgtgggcatcaactcctttggcttcgggggctccaacgtg
cacgtcatcctgaggcccaacacgcagccgcccccggcacccgccccacacgccaccctg
ccccgtctgctgcgggccagcggacgcacccccgaggccgtgcagaagctgctggagcag
ggcctccagcacagccaggacctggctttcctgagtatgctgaatgacatcgcggccgtc
cccaccaccgccatgcccttccgtggctacgccgtgctgggtggtgagcgtggtggccca
gaggtgcagcaggtgcccgctggcaagcgcccactctggttcatctgctctgggatgggc
acacagtggcgtgggatggggctgagcctcatgcgcctggaccgcttccgagattccatc
ctgcgctccgatgaggctgtgaagccgttcggcctgaaagtgtcacagctgctgctgagc
acagacgagggcacctttgatgacattgtccattccttcgtgagcctgaccgccatccag
ataggcctcatagacctgctgagctgcgtggggctgaggccagatggcatcatcggccac
tccctgggggaggtggcctgtggctatgccgacggctgcctgtcccaggaggaggccgtc
ctcgctgcctactggaggggacagtgcatcaaagaagcccatctcccgctgggcgccatg
gcagctgtgggcttgtcctgggaggaatgtaaacagcgctgccccccgggcgtggtgccc
gcctgccacaactccaaggacacagtcaccatctcgggacctcaggccccggtgtttgag
ttcgtggagcagctgaggaaggagggtgtgtttgccaaggaggtgcggaccggcggtatg
gccttccactcttacttcatggaggccatcgcacccccactgctgcaggcgctcaagaag
gtgatccgggagccaaagccacgttcagcccgctggctcagcacctctatccccgaggcc
cagtggcacggcagcctggcacgcacgtcctccgccgagtacaatgtcaacaacctggtg
agccctgtgctgttccaggaggccctgtggcacgtgcctgagcatgcagtggtgctggag
atcgcgccccatgccctgctgcaggctgtcctgaagcgtggcctgaagccgagctgcacc
atcatccccctgatgaaaaaggatcacagggacaacctggagttcttcctcgccggcatc
ggcaggctgcacctctcaggcattgacgccaaccccaatgccttgttcccgcctgtggag
tttccagctccccgaggaacccccctcatctccccactcatcaagtgggaccacagcctg
acctgggacgtgccggccgccgaggacttccccaacggctctggctccccctcggccgcc
gtctacaacattgacaccagctccgagtctcctgaccactacctggtggaccacaccctc
gatggtcgcgtcatcttccccgccaccggctacctgagcatagtgtggaagacgctggcc
cgcgccctgggcctggccattgagcagctgcccgtggtgtttgaggacgtggtgctgcac
caggccaccatcctgcccaagactgggactgtgtccctggaggtgcggctcctggaggcc
tcccgcgcctttgaggtgtcagagaacggcaacctgatagtgagcgggaaggtgtaccag
tgggatgaccctgaccccaggctcttcgacctcccggagagccccacccccaaccccgcg
gagcccctcttcctggcccaggctgaagtttacagggagctgcgtctgcgcggctacgac
tacggccctcacttccagggcatcctggaggccagcctggaaggtgactcagggaagctg
ctgtggaaggataactgggtgagcttcatggacaccatgctgcagatgtccatcctgggc
ttggccaagcacggcctgcacctgcccacccgcatcaccgccatccacattgaccctgcc
acccacaggcagaaactgtacacactgcaggacaaggcccaagtggctgacgtggtggtg
agcaggtggctgagcgtcacagtggccggaggtgtccacatctcccggctccacactgag
tccgccccacggcggcagcaggagcagcatgtgcccatcctggagaagttttgcttcact
ccccacatggaggagggatgcctgtctgagcgcactgccctgcaggaggagctgcaactg
tgcaaggggctggcgcaggcactgcagaccaaggtgacccagcaggggctgaagatggcg
gtgcccggactggatggggcccaggtcccccgggatccctcacagcaggaactgccccgg
ctgttgtgggctgcctgcaggcttcagctcaacgggaacctgcagctggagctggcacag
gtgctggcccaggagaggcccaagctgccagaggaccctctgctcagcggcctcctggac
tccccggcactcaaggcctgcctggacactgcctttgagaatatgcccagcccgaagatg
aaggtggtggaggtgctggctggccacggtcacctgtattcccgcatcccaggcctgctc
agcccccatcccctgctgcagctgagctacacggccactgaccgccacccccaggccctg
gaggctgcccaggccgagctgcagcagcacgacgttgcccagggccagtgggaccccgca
gaccctgcccccagcgccctgggcagcgctgacctcctggtgtgcaactgtgctgtggct
gccctcggggacccggcctcagctctcagcaacatggtggctgccctgagagaagggggc
ttcctgctgctgcacacactgctccgggggcaccccctgggggacaccatggccttcctc
acctccgctgagccgcagtatggccagggcatcctgagccaggacgcgtgggagagcctc
ttctccagggtgtcgctgcgcctggtgggcctgaagaagtccttctacggctccacactc
ttcctgtgccgccggcccagcccgcagggcagccccatcttcctgcccgtggacgacacc
agcttccgatgggtggagtctctgaagggcatcctggctgacgaagactcctcccagccc
gtgtggctgaaggccatcaactgttccacctcaggcgtggtgggcttggtgaactgtctc
cgccaagagctcggcgggcaccgcctccggtgtgtgctgctctccaacctgagcagcacc
tcccgcgtcccggaggtggacccgggctccgcagaactgcagaaggtgttgcagggagac
ctggtgatgaacgtctaccgcgatggggcctggggggccttccgccacttcctgctggag
gaggacaagcctgaggagctgacggcacacgcctttgtgaccaccctcacccggggggac
ctgtcctccatccgctgggtctgctcctcgctgcgccacgcccagcccacccaccctggc
gcccagctctgcacagtctactacgcctccctcaacttccgcgacatcatgctggccact
ggcaagctgtcccctgatgccatcccagggaagtggacctcccaggacagcctgttaggc
atggagttctcaggccgagatgccagcggcaagcgtgtgatgggactggtgcctgccgag
ggcctggccacctctgtcttgctgtcaccagacttcctctgggatgtgccctccaactgg
accctggaggaggcggcctcagtgcctgttgtctacagcacagcctactacgcactggtg
gtgcgcgggcgggtgcgccccggggagacggtgctcatccactcgggctcaggcggcgtg
ggccaggccgccatcgccatcgccctcagtctgggctgccgcgtcttcaccaccgtgggg
tcggctgagaagcgggtgtacctccaggccaggttcccccagctcgacagcaccagcttc
gccaactcccgggacacgtccttcgagcagcatgtgctgcggcacacgggcgggaagggt
gttgacctggtcttgaactccttggcggaagagaagctgcaggccagcgtgaggtgcttg
gctatgcacggtcgcttcctggaaattggcaaattcgacctttctcagaaccacccactc
ggcatggccatcttcctaaagaacgtgacattccatggggtcctgctggatgcgttcttc
aacgggagcagtgctgactggcgggaggtgtcggcgcttgtgcaggccggtatccgggat
ggggtggtacggcccctcaagtgcacggtgttccccggggcccaggtggaggacgccttc
cgctacatggcccaagggaagcacattggcaaagtcgtcgtgcaggtgcttgcggaggag
ccggaggcagtgctgaagggggccaaacccaagctgatgtcggccatctccaagaccttc
tgcccggcccacaagagctacatcatcactggtggtctgggtggcttcggcctggagttg
gcgcagtggctgatacagcgcggggtgcagaagctcgtgttgacctctcgctctgggatc
cggacaggctaccaggccaagcaggtccgccggtggaggcgccagggcgtacaggtgcag
gtgtccaccagcaacgtcagctcactggagggggcccggggcctcattgccgaggcggcg
cagcttgggcccgtgggcggcgtcttcaacctggccgtggtcttgagagacgccttgctg
gagaaccagaccccagagttcttccaggacgtctgcaagcccaagtacagcggcaccctg
aacctggacagggtgacccgagaggcgtgccctgagctggactactttgtggtcttctcc
tctgtgagttccggacgcggcaatgcgggacagagcaactacggctttgccaattccgcc
atggagcgcatctgtgagaaacgccggcacgaaggcctcccaggcctggccgtgcagtgg
ggcgccatcggcgacgtgggccttttggcggatatgagcatcaacgacacggtcatcggt
ggcacgctgccgcagcgcatggcctcctgcctggaggtgctggacctcttcctgaaccag
ccccacatggtcctgagcagcttcgtgctggctgagaaggctgcggcctacagggacagg
gacagccagcaggacgtggtggaggccgtggcacacatcctgggcatccgcgacttggcc
gctgtcaacctggacagctcactggcggacctgggcctggactcactcatgagcgtggag
gtgcgtcagacgctggagcgtgagctcaacctggtgctgtctgtgcgcgaggtgcggcag
ctcacgctccggaaactgcaggagctgtcctcaaaggcggatgcagccaacgagctggca
tcccccacgcccaaggaggatggtctggcccagcagcagactcagctgaacctgcgctcc
ctgctggtgaacccggagggccccaccctgatgcggctcaactcggtgcagagctcggag
cggcccctgttcctggtgcacccaatcgagggctccaccaccgtgttccacagcctggcc
tcccggctcagcatccccacctatggcctgcagtgcacccgagctgcacccctcgacagc
atccatagcctggctgcctactacatcgactgcatcaggcaggtgcagcccgagggcccc
taccgcgtggccggctactcctacggggcctgcgtggcctttgaaatgtgctcccagctg
caggcccagcagagcccggcccccacccacaacagcctcttcctgttcgacggctcgccc
acctacgtactggcctacacccagagctaccgggcaaagctgaccccaggctgtgaggct
gaggccgagacggaggccatatgcttcttcgtgcagcagttcacggacatggagcacaac
aaggtgctggaggcgctgctgccgctgaagggcctggaggagcgtgtggcagccgccgtg
gacctgatcatcaagagccaccaaggcctggaccgccaggagctgagcttcgcggccctg
tctttctactacaagctgcgtgccgctgagcagtacacacccaaggccaagtaccatggc
aacgtgatgctactgcgcgccaagacgggtggcgcctatggcgaggacctgggcgcggac
tacaacctctcccaggtatgtgatgggaaagtatctatccacgtcatcgagggcgaccac
cgtacgctgctggagggcagtggcctggagtccatcgtcagcatcatccacagctccctg
gctgagccacgcgtgagcgtgcgggagggctag
DBGET
integrated database retrieval system
