Nomascus leucogenys (northern white-cheeked gibbon): 100599625
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Entry
100599625 CDS
T03265
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04120
Ubiquitin mediated proteolysis
nle04144
Endocytosis
nle04330
Notch signaling pathway
nle04668
TNF signaling pathway
nle04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100599625 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
100599625 (ITCH)
04668 TNF signaling pathway
100599625 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100599625 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100599625 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
nle04131
]
100599625 (ITCH)
04121 Ubiquitin system [BR:
nle04121
]
100599625 (ITCH)
Enzymes [BR:
nle01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
100599625 (ITCH)
Membrane trafficking [BR:
nle04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
100599625 (ITCH)
Ubiquitin system [BR:
nle04121
]
Ubiquitin ligases (E3)
HECT type E3
100599625 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
100599625
NCBI-ProteinID:
XP_003273589
Ensembl:
ENSNLEG00000010045
UniProt:
G1RGD4
LinkDB
All DBs
Position
13:complement(29540746..29684712)
Genome browser
AA seq
864 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLGGDKEPTETIGDLSICLDGLQLESEVVTNGETTCSESASQNDDGSRSKDETRVSTNES
DDPEDAGAGENRRVSGSNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNTNTNTSEGATSGLIIPLTITGGSGPRPLNPVTQAPLPPGWEQRVDQH
GRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQ
WQLQRSQLQGAMQQFNQRFIYGNQDLFATSQSKEFDPLGPLPPGWEKRTDSNGRVYFVNH
NTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNG
PQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWV
IFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYRLQINPASYINPDHLKYFR
FIGRFIAMALFHGKFIDTGFSLPFYKCILNKPVGLKDLESIDPEFYNSLIWVKENNIEEC
GLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMLAEWRMSRGVEEQTQAFFE
GFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQITWFWQFVKEI
DNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPP
YKSYEQLKEKLLFAIEETEGFGQE
NT seq
2595 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacaacttggttcaatgggtagcctcaccatgaaatcacagctt
cagatcactgtcatctcagcaaaacttaaggaaaataagaagaattggtttggaccaagt
ccttacgtagaggtcacagtagatggacagtcaaagaagacagaaaaatgcaacaacaca
aacagtcccaagtggaagcaaccccttacagttatcgttacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatttatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgactttg
cagcttggaggtgacaaagagccaacagagacaataggagacttgtcaatttgtcttgat
gggctacagttagagtctgaagttgttactaatggtgaaactacatgttcagaaagtgct
tctcagaatgatgatggttccagatccaaggatgaaacaagagtgagcacaaatgaatca
gatgaccccgaagatgcaggagctggtgaaaataggagagtcagtgggagtaattctcca
tcgctctcaaatggtggttttaaaccttctagacctccaagaccttcacgaccaccacca
cccaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
gggtctagtacaggctctctgccgccgacaaatacaaatacaaatacaaatacatctgaa
ggagcaacatctggattaataattcctcttactataactggaggctcaggccctaggcca
ttaaatcctgtaactcaagctcccttgccacctggttgggagcagagagtggaccagcat
gggcgagtttactatgtagatcatgttgagaaaagaacaacatgggatagaccagaacct
ctacctcctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccat
ttcacaagaacaacaacgtggcagaggccaacactggaatccgtccgcaactatgaacaa
tggcagctacagcgtagtcagcttcaaggagcaatgcagcagtttaaccagagattcatt
tatgggaatcaagatttatttgctacatcacaaagtaaagaatttgatcctcttggtcca
ttgccacccggatgggagaagagaacagacagcaatggcagagtatatttcgtcaaccac
aacacacgaattacacaatgggaagaccccagaagtcaaggtcaattaaatgaaaagccc
ttacctgaaggttgggaaatgagattcacagtggatggaattccgtattttgtggaccac
aatagaagaactaccacctatatagatccccgcacaggaaaatctgccctagacaatgga
cctcagatagcctatgttcgggacttcaaagcaaaggttcagtatttccggttctggtgt
cagcaactggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgag
gattcctttcaacagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtg
atttttccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttctt
ttgtcacatgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataac
taccgcttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgt
tttattggcagatttattgccatggctctgttccatgggaaattcatagacacaggtttt
tctttaccattctataagtgtatcttgaacaaaccagttggactcaaggatttagaatct
attgatccagaattttacaattctctcatctgggttaaggaaaacaatattgaggaatgt
ggtttggaaatgtacttctccgttgacaaagaaattctaggtgaaattaagagtcatgat
ctgaaacctaatggtggcaatattcttgtaacagaagaaaataaagaggagtacatcaga
atgttagctgagtggaggatgtctcgaggtgttgaagaacagacacaagctttctttgag
ggctttaatgaaattcttccccagcaatatttgcagtactttgatgcaaaggaattagag
gtccttttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctac
cgtcattatacgaggaccagcaaacaaatcacgtggttttggcagtttgttaaagaaatt
gataatgagaagagaatgagacttctacagtttgttactggaacctgccgattgccagta
ggaggatttgctgacctcatggggagcaatggaccacagaaattctgcattgaaaaagtt
gggaaagaaaattggctacccagaagtcatacctgttttaatcgcctggacctgccacca
tacaagagctatgagcaactgaaggagaagctgttgtttgccatagaagaaacagaagga
tttggacaagagtaa
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