KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100601930
Entry
100601930         CDS       T03265                                 
Symbol
DHFR2
Name
(RefSeq) dihydrofolate reductase 2, mitochondrial
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00670  One carbon pool by folate
nle00790  Folate biosynthesis
nle01100  Metabolic pathways
nle01240  Biosynthesis of cofactors
nle01523  Antifolate resistance
nle04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:nle00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100601930 (DHFR2)
   00670 One carbon pool by folate
    100601930 (DHFR2)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    100601930 (DHFR2)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100601930 (DHFR2)
Enzymes [BR:nle01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     100601930 (DHFR2)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 100601930
NCBI-ProteinID: XP_003261741
LinkDB
Position
21:27030953..27035997
AA seq 223 aa
MLRHVKEFEEGNFAAFLAWLPGVASKLSSEVLTAAVMVRLLNCIVAVSQNMGIGKNGDLP
WPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLEDRINLVLSRELKEPP
QGAHFLARSLDDALKLTEQPELANKVDMIWIVGGSSVYKEAMNRSGHLKLFVTRIMQDFE
SDMFFSEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
NT seq 672 nt   +upstreamnt  +downstreamnt
atgctgagacacgtaaaagaatttgaagaagggaatttcgcggcattcttggcctggctt
cctggtgtagccagcaagctcagctcagaggtgctaaccgctgctgtcatggttcgtttg
ctaaactgcatcgtcgctgtgtcccaaaacatgggcatcggcaagaacggggacctgccc
tggccgccgctccggaatgaattcaggtatttccagagaatgaccacaacttcttcagta
gaaggtaaacagaatctggtgattatgggtaggaagacctggttctccatccctgagaag
aatcgacctttagaggatagaattaatttagttctcagcagagaactcaaggaacctcca
caaggagctcattttcttgccagaagtttggatgatgccttaaaacttactgaacaacca
gaattagcaaataaagtagacatgatttggatagttggtggcagttctgtttataaggaa
gccatgaatcgctcaggccatcttaaactatttgtgacaaggatcatgcaggactttgaa
agtgacatgtttttttcagaaattgacttggagaaatataaacttctgccagaataccca
ggtgttctctctgatgtccaggaggagaaaggcattaagtacaaatttgaagtatatgag
aagaatgattaa

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