Nomascus leucogenys (northern white-cheeked gibbon): 100602671
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Entry
100602671 CDS
T03265
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle04014
Ras signaling pathway
nle04072
Phospholipase D signaling pathway
nle04148
Efferocytosis
nle04360
Axon guidance
nle04625
C-type lectin receptor signaling pathway
nle04630
JAK-STAT signaling pathway
nle04650
Natural killer cell mediated cytotoxicity
nle04660
T cell receptor signaling pathway
nle04670
Leukocyte transendothelial migration
nle04722
Neurotrophin signaling pathway
nle04920
Adipocytokine signaling pathway
nle04931
Insulin resistance
nle05168
Herpes simplex virus 1 infection
nle05205
Proteoglycans in cancer
nle05208
Chemical carcinogenesis - reactive oxygen species
nle05211
Renal cell carcinoma
nle05220
Chronic myeloid leukemia
nle05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100602671 (PTPN11)
04630 JAK-STAT signaling pathway
100602671 (PTPN11)
04072 Phospholipase D signaling pathway
100602671 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100602671 (PTPN11)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100602671 (PTPN11)
04660 T cell receptor signaling pathway
100602671 (PTPN11)
04670 Leukocyte transendothelial migration
100602671 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
100602671 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
100602671 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100602671 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
100602671 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100602671 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
100602671 (PTPN11)
05211 Renal cell carcinoma
100602671 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100602671 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
nle01009
]
100602671 (PTPN11)
Enzymes [BR:
nle01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
100602671 (PTPN11)
Protein phosphatases and associated proteins [BR:
nle01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
100602671 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
Y_phosphatase3
PTPlike_phytase
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
100602671
NCBI-ProteinID:
XP_030677298
Ensembl:
ENSNLEG00000000078
LinkDB
All DBs
Position
10:79595436..79689827
Genome browser
AA seq
597 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW
QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI
DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK
RKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaatatcactggtgtggaggcagaaaacctactg
ttgacaagaggagttgatggcagttttttggcaaggcctagtaaaagtaaccctggagac
ttcacactttctgttagaagaaatggagctgtcacccacatcaagattcagaacactggt
gattactatgacctgtatggaggggagaaatttgccactttggctgagttggtccagtat
tacatggaacatcacgggcaattaaaagagaagaatggagatgtcattgagcttaaatat
cctctgaactgtgcagatcctacctctgaaaggtggtttcatggacacctctctgggaaa
gaagcagagaaattattaactgaaaaaggaaaacatggtagttttcttgtacgagagagc
cagagccaccctggagattttgttctttctgtgcgcactggtgatgacaaaggggagagc
aatgacggcaagtctaaagtgacccatgttatgattcgctgtcaggaactgaaatacgat
gttggtggaggagaacggtttgattctttgacagatcttgtggaacattataagaagaat
cctatggtggaaacattgggtacagtactacaactcaagcagccccttaacacgactcgt
ataaatgctgctgaaatagaaagcagagttcgagaactgagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacaggagtgcaaa
cttctctacagccgaaaagagggtcaaaggcaagaaaacaaaaacaaaaatagatataaa
aacatcctgccctttgatcataccagggttgtcctacacgatggtgatcccaatgagcct
gtttcagattacatcaatgcaaatatcatcatgcctgaatttgaaaccaagtgcaacaat
tcaaagcccaaaaagagttacattgccacacaaggctgcctgcaaaacacagtgaatgac
ttttggcggatggtgttccaagaaaactcccgagtgattgtcatgacaacgaaagaagtg
gagagaggaaagagtaaatgtgtcaaatactggcctgatgagtatgctctaaaagaatat
ggcgtcatgcgtgttaggaacgtcaaagaaagcgctgctcatgactatacgctaagagaa
cttaaactttcaaaggttggacaagctctactccaggggaatacggagagaacggtctgg
caataccactttcggacctggccagaccacggagtgcccagcgaccccgggggcgtgctg
gacttcctggaggaggtgcaccataagcaggagagcatcatggatgcagggccggttgtg
gtgcactgcagtgctggaattggccggacagggacgttcatcgtgattgatattcttatt
gacatcatcagagagaaaggtgttgactgcgacattgacgttcccaaaaccatccagatg
gtgcggtctcagaggtcagggatggtccagacagaagcacagtaccgatttatctatatg
gcggtccagcattatattgaaacactacagcgcaggattgaagaagagcagaaaagcaag
aggaaagggcatgaatatacaaatattaagtattctctagcggaccagacgagtggagat
cagagccccctcccgccttgtactccaacgccaccctgtgcagaaatgagagaagacagt
gctagagtctatgaaaacgtgggcctgatgcaacagcagaaaagtttcagatga
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