| Entry |
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| Symbol |
RAPGEF4
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| Name |
(RefSeq) rap guanine nucleotide exchange factor 4 isoform X1
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| KO |
| K04351 | Rap guanine nucleotide exchange factor 4 |
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| Organism |
nle Nomascus leucogenys (northern white-cheeked gibbon)
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| Pathway |
| nle04072 | Phospholipase D signaling pathway |
| nle04261 | Adrenergic signaling in cardiomyocytes |
| nle04670 | Leukocyte transendothelial migration |
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| Brite |
KEGG Orthology (KO) [BR:nle00001]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
100602878 (RAPGEF4)
04072 Phospholipase D signaling pathway
100602878 (RAPGEF4)
04024 cAMP signaling pathway
100602878 (RAPGEF4)
09133 Signaling molecules and interaction
04081 Hormone signaling
100602878 (RAPGEF4)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
100602878 (RAPGEF4)
09152 Endocrine system
04911 Insulin secretion
100602878 (RAPGEF4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100602878 (RAPGEF4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:nle04131]
100602878 (RAPGEF4)
Membrane trafficking [BR:nle04131]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
Rab associated proteins
100602878 (RAPGEF4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
22a:73073871..73405301
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| AA seq |
1011 aa
MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGY
YENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDN
TPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENT
PLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTE
LVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLP
TEEEKKECDEELQDTLLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHL
STTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD
FGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV
PAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVF
MPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMA
FLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQK
RQPIRGSDEVLFKVYCMDHTYTTIRVPVAASVKEVISAVADKLGSGEGLIIVKMSSGGEK
VVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQM
TIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKR
VQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLM
DPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTART
VRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP |
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| NT seq |
3036 nt +upstreamnt +downstreamnt
atggtcgctgcgcacgctgcccattcttcctcctccgccgagtggatcgcctgcctggat
aaaagaccattggagcgatccagtgaagatgtggatataatcttcactcgactgaaagaa
gtgaaagcttttgagaaatttcacccaaatctccttcatcagatttgcttatgtggttat
tatgagaatctggaaaagggaataacactatttcgccagggtgatattggaacaaactgg
tatgctgtcttggcagggtctttggatgttaaagtatctgagaccagcagtcaccaggat
gctgtgaccatctgtaccctgggaattgggactgcctttggagagtccattctggacaac
acaccccgccatgcaaccatcgttaccagggagagcagtgaactgctccgcatcgagcag
aaggacttcaaggcactatgggagaaatatcgacagtatatggcaggacttctggctcct
ccttatggtgttatggaaacgggctctaacaatgacaggattcctgacaaggagaacaca
cctctcattgaacctcacgttcctcttcgtcctgctaacaccattaccaaggtcccttca
gagaagatcctcagagctggaaaaattttacgaaatgccattctctctcgagcacctcac
atgataagagatagaaaataccacctaaagacatacagacaatgctgtgtgggaactgag
ctggtggactggatgatgcagcagacaccatgcgttcactcccggactcaagctgttggc
atgtggcaagtcctgttagaagatggtgttctcaaccacgtggaccaggagcaccatttc
caagacaaatatttattctatcgatttctggatgatgagcacgaggatgcccctttgcct
actgaggaggagaagaaggagtgcgatgaggagctccaggacaccctgctgctgctgtca
cagatgggccccgacgcccacatgaggatgatcctccgcaaaccacctggccagaggact
gtggatgacctagagattatctatgaggagcttcttcatattaaagccttatcccatctt
tctaccacagtgaagcgagagttagcaggtgttctcatttttgagtctcatgccaaagga
gggactgtgttgtttaaccagggggaagaaggtacctcctggtacattattctgaaagga
tcagtgaatgtagtcatttacggcaagggtgtggtctgcaccctgcatgaaggagatgac
ttcggcaagttagcactagtgaatgatgccccacgagctgcctctatcgtcttacgagaa
gataattgccatttcttaagagtagacaaggaggatttcaaccggatcctgagggacgtg
gaggcgaatacagtcagacttaaagaacatgaccaagatgtcttggtgctggagaaggtc
ccagcagggaacagagcttctaatcaaggaaactcacagcctcagcaaaagtatactgtg
atgtcaggaacacctgaaaaaattttagagcattttctagaaacaatacgccttgaggca
actttaaatgaagcaacagattctgttttaaatgactttattatgatgcactgtgttttt
atgccaaatacccagctttgcccagcactggtggcccactaccacgcacagccttcacaa
ggtacagaacaggagaaaatggattatgccctcaacaataagaggcgagtcatccgcctg
gttctacagtgggctgccatgtatggagacctcctacaagaggatgacgtgtctatggcc
ttcctggaggagttttatgtatctgtatcagatgatgcccggatgattgctgccctcaag
gagcaactgccagagttggagaagattgtcaagcaaatctcagaagatgcaaaggcacca
caaaagaagcacaaggttcttttgcaacagttcaatacgggcgatgagagagcccagaag
cgccagcctatccgcggctctgatgaagttctgtttaaggtctattgcatggaccacacc
tacacaaccattcgggtgccagtggccgcctcggtgaaggaagtcatcagtgcagttgcc
gacaagctgggctccggggagggcctgataatagtcaagatgagttccggaggagaaaag
gtggtgctcaaacctaatgatgtttcagtatttacgacgctcaccattaatggacgcctg
tttgcttgcccgcgagagcaattcgattcactgactcccttaccagaacaggaaggccca
actgttggaacagtgggaacttttgaactgatgagctccaaagatttagcataccagatg
acaatttatgattgggaactcttcaactgcgtgcatgagctggagctaatctatcacaca
tttggaaggcataattttaaaaagaccacagcaaacttggatttgttcctgaggagattt
aatgaaattcagttttgggtcgtcactgagatctgcctttgttctcagctcagcaagcgt
gttcagctattaaaaaaatttattaagatagcagcccactgtaaggagtataaaaatctg
aattccttttttgccatcgtcatgggactaagtaacgttgctgtgagccgcttggcacta
acgtgggagaaactgccaagcaagttcaagaagttctatgcggagtttgaaagtttaatg
gacccttcaaggaaccacagggcctacaggctgacggtagctaagctggaacctcctctc
atccccttcatgcctttgctcattaaagatatgacatttactcatgaggggaacaagacg
ttcattgacaatctagtaaactttgaaaaaatgcgcatgattgcaaatacggccagaaca
gtgagatactacaggagccaacccttcaatcctgatgcagctcaagctaataagaaccat
caggatgtccggagttatgtacggcaattaaatgtgattgataaccagagaactttatca
cagatgtcacacagattagagcctcgtcgaccatag |
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