KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100605385
Entry
100605385         CDS       T03265                                 
Name
(RefSeq) aldo-keto reductase family 1 member C4 isoform X1
  KO
K00037  3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00120  Primary bile acid biosynthesis
nle00140  Steroid hormone biosynthesis
nle01100  Metabolic pathways
nle05208  Chemical carcinogenesis - reactive oxygen species
Module
nle_M00104  Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
nle_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:nle00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    100605385
   00140 Steroid hormone biosynthesis
    100605385
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    100605385
Enzymes [BR:nle01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.50  3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
     100605385
    1.1.1.225  chlordecone reductase
     100605385
    1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase
     100605385
SSDB
Motif
Pfam: Aldo_ket_red
Other DBs
NCBI-GeneID: 100605385
NCBI-ProteinID: XP_030675218
Ensembl: ENSNLEG00000011321
LinkDB
Position
9:complement(110036075..110076728)
AA seq 322 aa
MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEVGFRHIDSAYLYDNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWCTFFRPQMVQPALESSLKKLQLDYVDLYLLHFPM
ALKPGETLLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
RLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAYSALGTQRLWIVDPNSPVLLEDPVL
CALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSEDMKVLDGLNR
NYRYIVMDFLMDHPDYPFSDEY
NT seq 969 nt   +upstreamnt  +downstreamnt
atggatcccaaatatcagcgtgtggagctaaatgatggtcatttcatgcctgtattggga
tttggcacctatgcacctccagaggttccgaggaacagagctgtggaggtcaccaaatta
gcgatagaagttggcttccgccatatagattctgcttatttatacgataatgaggagcag
gttggactggccatccgaagcaagattgcagatggcagtgtgaagagagaagacatattc
tacacttcaaagctttggtgcactttctttcgaccacagatggtccaaccagccttggaa
agctcactgaaaaaacttcaactggactatgttgacctctatcttcttcatttcccaatg
gctctcaagccaggtgagacgctactaccaaaagatgaaaatggaaaagtaatattcgac
acagtggatctctgtgccacatgggaggtcatggagaagtgtaaggatgcaggattggcc
aagtccatcggggtgtccaacttcaaccgcaggcagctggagatgatcctcaacaagcca
aggctcaagtacaagcctgtctgcaaccaggtagaatgtcatccttacctcaaccagagc
aaactgctggatttctgcaagtcaaaagacattgttctggttgcctatagtgctctggga
acccaacgactatggatagtggacccgaactccccagttcttttggaggacccagttctt
tgtgccttagcaaagaaacacaaacgaaccccagccctgattgccctgcgctaccagctg
cagcgtggggttgtggtcctggccaagagctacaacgagcagcggatcagagagaatgtc
caggtttttgaattccagttgacatcagaggatatgaaagttctagatggcctaaacaga
aattatcgatatattgtcatggattttcttatggaccaccctgattatccattttcagat
gaatattag

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