Nomascus leucogenys (northern white-cheeked gibbon): 100606756
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Entry
100606756 CDS
T03265
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
nle
Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00061
Fatty acid biosynthesis
nle00620
Pyruvate metabolism
nle00640
Propanoate metabolism
nle01100
Metabolic pathways
nle04152
AMPK signaling pathway
nle04910
Insulin signaling pathway
nle04920
Adipocytokine signaling pathway
nle04922
Glucagon signaling pathway
nle04931
Insulin resistance
nle04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
nle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100606756 (ACACB)
00640 Propanoate metabolism
100606756 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100606756 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100606756 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100606756 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100606756 (ACACB)
04922 Glucagon signaling pathway
100606756 (ACACB)
04920 Adipocytokine signaling pathway
100606756 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100606756 (ACACB)
04931 Insulin resistance
100606756 (ACACB)
Enzymes [BR:
nle01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100606756 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100606756 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100606756 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
100606756
NCBI-ProteinID:
XP_030677195
Ensembl:
ENSNLEG00000001505
LinkDB
All DBs
Position
10:76214212..76372134
Genome browser
AA seq
2458 aa
AA seq
DB search
MVLLLCLSCLIFSCLTFSWLKIWGNMTDSKPITKSKSEANFIPSEEPFLASDNSGETPQR
NGEGHSLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT
GTQGLEAPDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV
AGSSRESTRKGSRASLGALSLEAYLTTGEAETRIPTMRPSMSGLHLVKRGREHKKLDLHR
DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT
PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL
PELLCKNGVAFLGPPSEAMWALGDKIASTIVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK
RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV
QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP
LAIFEFMEQCAVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL
PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE
GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA
LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL
NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGIKYILKVARQSLTMFVLIM
NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP
SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCVVAR
LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPIFSIK
LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP
SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV
EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD
ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP
ENLKKLILSETTIFDVLPAFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV
VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR
NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVCIQCADHLEDEALVP
ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL
ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY
LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS
RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF
GNKQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYIYDFPEMFRQALFKLWGSPDKYPK
DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG
SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK
YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL
AYEEIVTISLVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL
GGVQIMYYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR
APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE
TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREKLPLMIFANWRGF
SGGMKDMYDQVLKFGAYIVDGLRQYTQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA
DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK
AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK
QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR
ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST
NT seq
7377 nt
NT seq
+upstream
nt +downstream
nt
atggtcttgcttctttgtctatcttgtctgattttctcctgtctgaccttttcctggtta
aaaatctgggggaacatgacggactccaagccgatcaccaagagtaaatcagaagcaaac
ttcatcccgagcgaagagccctttctagcctctgataactcaggagagacaccgcagaga
aatggggagggccactctctgcccaagactcccagccaggccgagccagcctcccacaaa
ggccccaaagatgctggtcggcggagaaactccctaccaccctcccaccagaagccccca
agaaaccccctttcttccagtgacgcagcaccctccccagagcttcaagccaacgggact
gggacacaaggtctggaggccccagataccaatggcctgtcctcctcagccaggccccag
ggccagcaagctggctcgccctccaaagaagacaagaagcaggcaaacatcaagaggcag
ctaatgaccaactttatcctgggctcttttgatgactactcctccgacgaggactctgtt
gccggctcatctcgtgagtctacccggaagggcagccgggccagcttgggggccctgtcc
ctggaggcttatctgaccacaggtgaagcggagacccgcatccccactatgaggccaagc
atgtcgggactccacctggtgaagaggggacgggaacacaagaagctggacctgcacaga
gactttaccgtggcttctcccgctgagtttgtcacacgctttgggggggatcgggtcatc
gagaaggtgcttattgccaacaacgggatcgctgccgtgaagtgcatgcgctccatccgc
aggtgggcctatgagatgttccgcaacgagcgggccatccggtttgttgtgatggtgacc
cccgaggaccttaaggccaacgcagagtacatcaagatggcggatcattacgtccccgtc
ccaggagggcccaataacaacaactatgccaatgtggagctgattgtggacattgccaag
agaatccctgtgcaggcggtgtgggctggctggggccatgcttcagaaaaccctaaactt
ccggagctgctgtgcaagaatggagttgctttcttaggccctcccagtgaggccatgtgg
gccttaggagataagatcgcctccaccattgtcgcccagacgctacaggtcccaaccctg
ccctggagtggaagcggcctgacagtggagtggacagaagatgatctgcagcagggaaaa
agaatcagtgtcccagaagatgtttatgacaagggttgcgtgaaagacgtagatgagggc
ttggaggcagcagaaagaattggttttccattgatgatcaaagcttctgaaggtggcgga
gggaagggaatccggaaggctgagagtgcggaggacttcccgatccttttcagacaagta
cagagtgagatcccaggctcgcccatctttctcatgaagctggcccagcacgcccgtcac
ctggaagttcagatcctcgctgaccagtatgggaatgctgtgtctctgtttggtcgcgac
tgctccatccagcggcggcatcagaagatcgtagaggaagcaccggccaccatcgcccct
ctggccatattcgagttcatggagcagtgtgccgtccgcctggccaagaccgtgggctat
gtgagtgcagggacagtggaatacctctatagccaggacggcagcttccacttcttggag
ctgaatcctcgcttgcaggtggaacatccctgcacagaaatgattgctgacgtcaatctg
ccggccgcccagctacagatcgccatgggcgtgccactgcaccggctgaaggatatccgg
cttctgtacggagagtcaccatggggagtgactcccatttcttttgaaaccccctcaaac
cctcccctcgcccgaggccacgtcattgccgccagaatcaccagcgaaaacccagacgag
ggttttaagccgagctccgggactgtccaggaactgaatttccggagcagcaagaacgtg
tggggttacttcagcgtggccgctactggaggcttgcacgagtttgcggattcccagttt
gggcactgcttctcctggggagagaaccgggaagaggccatttcgaacatggtggtggct
ttgaaggaactgtccatccgaggcgactttaggactaccgtggaatacctcattaacctc
ctggagactgagagcttccagaacaatgacatcgacactgggtggttggactacctcatt
gctgagaaagtgcaggcggagaaaccagatatcatgcttggggtggtatgcggggccttg
aacgtggccgatgcgatgttcagaacgtgcatgacagatttcttacactccctggaaagg
ggccaggtcctcccagcggattcgctactgaacctcgtagatgtggaattaatttacgga
ggcattaagtacattctcaaggtggcccggcagtctctgaccatgttcgttctcatcatg
aatggctgccacatcgagatcgacgcccaccggctgaatgatggggggctcctgctctcc
tacaatgggaacagctacaccacctacatgaaggaagaggttgacagttaccgaattacc
atcggcaataagacatgtgtgtttgagaaggagaacgatcctacggtcctgagatccccc
tcggctgggaagctgacacagtacacagtggaggacgggggccacgttgaggctgggagc
agctacgccgagatggaggtgatgaagatgatcatgaccctgaacgtgcaggaaagtggc
cgggtgaagtacatcaagcgtccaggtgccgtgctggaagcaggctgcgtggtggccagg
ctggagcttgatgacccttctaaagtccacccggctgaaccgttcacaggagaactccct
gcccagcagacactgcccatcctcggagagaagctgcaccaggtcttccacagcgtcctg
gaaaacctcaccaacgtcatgagtggcttttgtctgccagagcccatttttagcataaag
ctgaaggagtgggtgcagaagctcatgatgaccctccggcacccgtcactgccgctgctg
gagctgcaggagatcatgaccagcgtggcaggccgcatccccgcccccgtggagaagtca
gtccgcagggtgatggcccagtatgccagcaacatcacctcggtgctgtgccagttcccc
agccagcagatagccaccatcctggactgccacgcagccaccctgcagcggaaggccgat
cgagaggtcttcttcatcaacacccagagcatcgtgcagttggtccagagataccgcagc
gggatccgtggctatatgaaaacagtggtgttggatctcctgagaagatacttgcgtgtt
gagcaccattttcagcaagcccactacgacaagtgtgtgataaacctcagggagcagttc
aagccagacatgtcccaggtgttggactgcatcttctcccacgcacaggtggccaagaag
aaccagctggtgatcatgttgatcgatgagctgtgtggcccagacccttccctgtcggac
gagctgatctccatcctcaacgagctcactcagttgagcaaaagcgagcactgcaaagtg
gccctcagagcccggcagatcctgattgcctcccacctcccctcctacgagctgcggcat
aaccaggtggagtccattttcctgtctgccattgacatgtacggccaccagttctgtccc
gagaacctcaagaaattaatactttcggaaacaaccatcttcgacgtcctgcctgctttc
ttctatcacgcaaacaaagtcgtgtgcatggcgtccttggaggtttacgtgcggaggggc
tacatcgcctatgagttaaacagcctgcagcaccggcagctcccggacggcacctgcgtg
gtagaattccagttcatgctgccctcctcccacccaaaccggatgaccgtgcccatcagc
atcaccaaccctgacctgctgaggcacagcacagagctcttcatggacagcggcttctcc
ccactgtgccagcgcatgggagccatggtagccttcaggagattcgaggacttcaccaga
aattttgatgaagtcatctcttgcttcgccaatgtgcccaaagacacccccctcttcagc
gaggcccgcacctccctgtactccgaggatgactgcaagagcctcagagaagagcccatc
cacattctgaatgtgtgcatccagtgtgcagaccacctggaggatgaggcactggtgcca
attttacggacgttcgtacagtccaagaaaaatatccttgtggattatggactccgacga
atcacattcttgattgcccaagagaaagaatttcccaagtttttcacattcagagcaaga
gatgagtttgcagaagatcgcatttaccgtcacttggaacctgccctggccttccagctg
gaactcaaccggatgcgtaacttcgacctgaccgccgtgccctgtgccaaccacaagatg
cacctttacctgggtgctgccaaggtgaaggaaggagtggaagtgacggaccataggttc
ttcatccgcgccatcatcaggcactctgacctgattacaaaggaagcctccttcgaatac
ctgcagaacgagggtgagcggctgctcctggaggccatggacgagctggaggtggcgttc
aataacaccagcgtgcgcaccgactgcaaccacatcttcctcaacttcgtgcccactgtc
atcatggaccccttcaagatcgaggagtctgtgcgctacatggttatgcgctatggcagc
cggttgtggaaactccgcgtgctgcaggctgaggtcaagatcaacatccgccagaccacc
accggcagtgccgttcccatccgcctgttcatcaccaatgagtcgggctactacctggac
atcagcctctacaaagaagtgactgactccagatccggaaatatcatgtttcactccttc
ggcaacaagcaagggccccagcacgggatgctgatcaatactccctacgtcaccaaggat
ctgctccaggccaagcgattccaggcccagtccctgggaaccacctacatctatgacttc
ccggagatgttcaggcaggctctctttaaactgtggggctccccagacaagtatcccaaa
gacatcctgacatacactgaattagtgttggactctcagggccagctggtggagatgaac
cgacttcctggtggaaatgaggtggggatggtggccttcaaaatgaggtttaagactcag
gagtacccagaaggacgggacgtgatcgtcatcggcaacgacatcacctttcgcattgga
tcctttggccccggggaggaccttctgtacctgcgggcatccgagatggcccgggcagag
ggcattcccaaaatctacgtggcagccaacagtggcgcccgtattggcatggcagaggag
atcaaacacatgttccatgtggcttgggtggacccagaagacccccacaaaggatttaaa
tacctgtacctgactccccaagactacaccagaatcagctccctgaactccgtccactgt
aaacacatcgaggaaggaggagaatccagatacatgatcacggatatcatcgggaaggat
gatggcttgggcgtggagaatctgaggggctcaggcatgattgctggggagtcctctctg
gcttacgaagagatcgtcaccattagcttggtgacctgccgagcccttgggattggggcc
tacttggtgaggctgggccagcgagtgatccaggtggagaactcccacatcatcctcacg
ggagcaagtgctctcaacaaggtcctgggaagagaggtctacacatccaacaaccagctg
ggtggcgttcagatcatgtattacaatggcgtctcccacatcaccgtgccagatgacttt
gagggggtttataccatcctggagtggctgtcctatatgccaaaggataatcacagccct
gtccctatcatcacacccactgaccccattgacagagaaattgaattcctcccatccaga
gctccctacgacccccggtggatgcttgcaggaaggcctcacccaactctgaagggaaca
tggcagagcggattctttgaccacggcagtttcaaggaaatcatggcaccctgggcgcag
actgtggtgacaggacgagcaaggcttggggggattcctgtgggagtgattgctgtggag
acacggactgtggaggtggcagtccctgcggaccctgccaacctggattccgaggccaag
ataattcagcaggcaggacaggtgtggttcccagactcagcctacaaaaccgcccaggcc
atcaaggacttcaaccgggagaagttgcccctgatgatctttgccaactggagggggttc
tctggtggcatgaaagacatgtatgaccaggtgctgaagtttggagcctacatcgtggac
ggccttagacaatacacacagcccatcctgatttatatcccgccctatgcggagctccgg
ggaggctcctgggtggtcatagacgccaccatcaacccgctgtgcatagaaatgtatgcg
gacaaagagagcagggggggtgttctggaaccagaggggacagtggagattaagttccga
aagaaagatctgataaagtccatgagaaggatcgatccagcttacaagaagctcatggaa
cagctaggggaacctgatctctcggacaaggaccgcaaggacctggagggccggctgaag
gctcgcgaggacctgctgctccccatctaccaccaggtggcggtgcagttcgccgacttc
cacgacacgcccggccggatgctggagaagggcgtcatatctgacatcctggagtggaag
accgcacgcaccttcctgtattggcgtctgcgccgcctcctcctggaggaccaggtcaag
caggagatcctgcaggccagcggggagctgagtcacgtgcacatccagtccatgctacgc
cgttggttcgtggagacggagggggccgtcaaggcctacttgtgggacaacaaccaggtg
gttgtgcagtggctggaacagcactggcaggcgggtgatggcccacgctccaccatccga
gagaacatcacgtacctgaagcatgactctgtcctcaagaccatccgaggcctggttgaa
gaaaaccccgaggtggccgtggactgtgtgatatacctgagccagcacatcagcccagct
gagcgggcgcaggttgttcacctgctgtctaccatggacagcccggcctccacctga
DBGET
integrated database retrieval system
