Neisseria meningitidis MC58 (serogroup B): NMB1341
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Entry
NMB1341 CDS
T00027
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase, E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
nme
Neisseria meningitidis MC58 (serogroup B)
Pathway
nme00010
Glycolysis / Gluconeogenesis
nme00020
Citrate cycle (TCA cycle)
nme00620
Pyruvate metabolism
nme00785
Lipoic acid metabolism
nme01100
Metabolic pathways
nme01110
Biosynthesis of secondary metabolites
nme01120
Microbial metabolism in diverse environments
nme01200
Carbon metabolism
nme01210
2-Oxocarboxylic acid metabolism
Module
nme_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nme00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
NMB1341 (pdhA)
00020 Citrate cycle (TCA cycle)
NMB1341 (pdhA)
00620 Pyruvate metabolism
NMB1341 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NMB1341 (pdhA)
Enzymes [BR:
nme01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
NMB1341 (pdhA)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AAF41716
UniProt:
Q9JZ12
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All DBs
Position
1359205..1361868
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AA seq
887 aa
AA seq
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MSTQLHDVDPIETQEWLDALSSVLEYEGGERAQYLLENLVKYCRDKGVRMPHGTTTPYLN
TVSVENEKGIPGDQNIEHRIRAFVRWNAAAIVLRAGKKDLELGGHIASFQSAATMYEVGF
NHFWKAKGEGEEGDLVFFQGHVAPGIYARAFVEGRLTEDQLNNFRQEVDGHGLPSYPHPH
LLPDFWQFPTVSMGLGPIMAIYQARFLKYLESRGLAKTKGRKVWCFCGDGEMDEPESQGA
IALAAREGLDNLIFVINCNLQRLDGPVRGNGKIIQELEGNFAGAGWNVVKVIWGRRWDRL
LAKDKDGILRQRMEECLDGDYQTYKSKDGAYVREHFFNTPELKALVADMTDEQLWALNRG
GHDPQKVYNAYDRAANHADGKPTVILAKTIKGYGMGASGEGQNVAHQAKKMDKASLKQFR
DRFDIPVTDEQIESGDLPYLTFAPDTEEYKYLHARRDALGGYLPQRKPTQEVLEVPELSA
FDAQLKSSGEREFSTTMAFVRILSTLLKDKKIGKRVVPIVPDESRTFGMEGMFRQYGIWN
PKGQQYTPQDKDQLMFYKESVDGQILQEGINEPGAMADWIAAATSYANSNFAMIPFYIYY
SMFGFQRIGDLAWAAGDMHARGFLLGGTAGRTTLNGEGLQHEDGHSHIQADLIPNCVSYD
PTFQYEVAVIVQDGLRRMYANNEDVFYYITLMNENYTHPDMPEGAEQDILKGMYLLKAGG
KGDKKVQLMGSGTILQEVIAGAELLKADFGVEADIWSCPSFNLLHRDAVEVERFNRLHPL
EAEKVPFVTSQLQGHDGPVIAATDYIRSYADRIRAYIPNDYHVLGTDGFGRSDSRANLRR
FFEVDRYNVAVAALAALAEQGKVSKETVQQAIEKYGIKADSAPSWKR
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtccacccaattacacgatgttgaccctatcgaaacccaagagtggctggacgcgtta
agctccgtcctcgaatatgaaggcggcgaacgcgcgcaatacctcttggaaaacctggtc
aaatactgccgcgacaagggcgtacgtatgccacacggcacgaccaccccgtatttgaat
accgtttcggttgaaaacgaaaaaggcattccgggcgaccaaaacatcgaacaccgcatc
cgcgcattcgtgcgctggaacgccgccgccatcgtattgcgcgccggcaagaaagatttg
gaactgggtgggcacatcgcatctttccaatctgccgccaccatgtacgaagtcggtttc
aaccacttttggaaagccaaaggcgaaggcgaagaaggcgatttggtcttcttccaaggt
cacgtcgccccgggcatctatgcacgcgcattcgtcgagggccgtctgaccgaagaccag
ctgaacaacttccgccaagaagtggacggacacggtctgccttcctatccgcacccccac
ctcttgcccgacttttggcagttcccgaccgtatccatgggcttggggcccatcatggcg
atttatcaggcgcgtttcctgaaatacttggaatcgcgtggtttggcaaaaaccaaaggc
cgtaaagtatggtgtttctgcggcgacggcgaaatggacgaacccgaatctcaaggtgca
atcgcactggctgcacgcgaaggcttggacaacctgattttcgtcatcaactgcaatctg
caacgcttggacggtccggtacgcggcaacggcaaaatcatccaagaattggaaggcaac
tttgccggcgccggctggaatgtcgtcaaagtcatttggggccgccgctgggaccgcctc
ttggcgaaagacaaagacggtatcctgcgccaacgtatggaagaatgtttggacggcgac
taccaaacttacaaatccaaagacggcgcgtatgtgcgcgaacacttcttcaatacgccc
gaactgaaagcattggttgccgatatgaccgatgagcaactctgggcattgaaccgcggc
ggccacgacccgcaaaaagtgtacaacgcctacgaccgcgcagcgaaccatgccgacggc
aaacctaccgtcatcttggcgaaaaccattaaaggttacggtatgggcgcatccggcgaa
ggtcagaacgttgcccaccaagccaaaaaaatggacaaagcgtccctgaaacaattccgc
gaccgctttgacattccggttaccgacgaacaaatcgaaagcggcgatctgccttacctg
acttttgcccccgatacggaagaatacaaatacctgcacgcacgccgcgatgctttgggc
ggctacctgccgcaacgcaaaccgacgcaggaagtattggaagtgcccgagctgtcagca
ttcgacgcacaactcaaatccagcggtgaacgcgagttctcgaccacgatggcattcgtc
cgcatcctgtccactttactgaaagacaaaaaaatcggcaaacgcgtcgtacctatcgtt
cccgacgaaagccgtactttcggcatggaaggtatgttccgccaatacggtatttggaat
ccgaaaggtcagcaatatacccctcaagacaaagaccaactgatgttctataaagaatcc
gttgacggtcaaatcttgcaagaaggtattaacgaaccgggcgcgatggccgactggatt
gcggctgcaaccagctacgccaacagcaacttcgccatgattccgttctacatttactat
tctatgttcggtttccaacgtatcggcgacttggcttgggcggcgggcgatatgcacgcg
cgcggcttcctgctgggcggtactgccggccgtacgacgctgaacggcgaaggcctgcaa
cacgaagacggccacagccacatccaggccgacctgattccgaactgcgtatcttatgac
ccgactttccaatacgaagtcgccgtcatcgtacaagacggtctgcgccgtatgtatgcc
aataatgaagacgtgttctactacatcaccctgatgaacgagaactacacccatccggat
atgcccgaaggtgcggaacaagacatcttgaaaggtatgtacctgctgaaagccggcggc
aaaggcgataagaaagttcaattgatgggctccggtaccatcctgcaagaagtcattgcc
ggtgccgagctgctgaaagccgacttcggcgtagaagcagacatctggtcttgcccgtcc
ttcaacctgctgcaccgcgacgctgtcgaggtagaacgcttcaaccgcctgcatccgctg
gaagccgaaaaagtacctttcgttacttcccaactgcaaggtcatgacggtccggttatt
gccgctaccgactatatccgcagctatgctgaccgtatccgcgcctacatcccgaacgac
taccacgtcttgggcactgacggtttcggccgttccgacagtcgcgccaacctgcgccgc
ttctttgaagtggatcgctacaacgttgccgtggccgcattggccgcattggcggaacaa
ggcaaagtcagcaaagaaaccgttcaacaagccattgagaaatacggcatcaaagccgat
tcagctcctagctggaaacgctga
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