Neisseria meningitidis 510612 (serogroup A): NMA510612_1721
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Entry
NMA510612_1721 CDS
T03438
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
nmx
Neisseria meningitidis 510612 (serogroup A)
Pathway
nmx00010
Glycolysis / Gluconeogenesis
nmx00020
Citrate cycle (TCA cycle)
nmx00620
Pyruvate metabolism
nmx00785
Lipoic acid metabolism
nmx01100
Metabolic pathways
nmx01110
Biosynthesis of secondary metabolites
nmx01120
Microbial metabolism in diverse environments
nmx01200
Carbon metabolism
nmx01210
2-Oxocarboxylic acid metabolism
Module
nmx_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nmx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
NMA510612_1721 (aceE)
00020 Citrate cycle (TCA cycle)
NMA510612_1721 (aceE)
00620 Pyruvate metabolism
NMA510612_1721 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NMA510612_1721 (aceE)
Enzymes [BR:
nmx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
NMA510612_1721 (aceE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AHW76007
UniProt:
X5F7K5
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All DBs
Position
1466068..1468731
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AA seq
887 aa
AA seq
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MSTQLHDVDPIETQEWLDALSSVLEYEGGERAQYLLENLVKYCRDKGVRMPHGTTTPYLN
TVSVENEKGIPGDQNIEHRIRAFVRWNAAAIVLRAGKKDLELGGHIASFQSAATMYEVGF
NHFWKAKGEGEEGDLVFFQGHVAPGIYARAFVEGRLTEDQLNNFRQEVDGHGLPSYPHPH
LLPDFWQFPTVSMGLGPIMAIYQARFLKYLESRGLAKTKGRKVWCFCGDGEMDEPESQGA
IALAAREGLDNLIFVINCNLQRLDGPVRGNGKIIQELEGNFAGAGWNVVKVIWGRRWDRL
LAKDKDGILRQRMEECLDGDYQTYKSKDGAYVREHFFNTPELKTLVADMTDEQLWALNRG
GHDPQKVYNAYDRAANHADGKPTVILAKTIKGYGMGASGEGQNVAHQAKKMDKASLKQFR
DRFDIPVTDEQIESGDLPYLTFAPDTEEYKYLHARRDALGGYLPQRKPTQEVLEVPELSA
FDAQLKSSGEREFSTTMAFVRILSTLLKDKKIGKRVVPIVPDESRTFGMEGMFRQYGIWN
PKGQQYTPQDKDQLMFYKESVDGQILQEGINEPGAMADWIAAATSYANSNFAMIPFYIYY
SMFGFQRVGDLAWAAGDMHARGFLLGGTAGRTTLNGEGLQHEDGHSHIQADLIPNCVSYD
PTFQYEVAVIVQDGLRRMYANNEDVFYYITLMNENYTHPDMPEGAEQDILKGMYLLKAGG
KGDKKVQLMGSGTILQEVIAGAELLKADFGVEADIWSCPSFNLLHRDAVEVERFNRLHPL
EAEKVPFVTSQLQGHDGPVIAATDYIRSYADRIRAYIPNDYHVLGTDGFGRSDSRANLRR
FFEVDRYNVAVAALAALAEQGKVSKETVQQAIEKYGIKADSAPSWKR
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtccacccaattacacgatgttgaccctatcgaaacccaagagtggctggacgcgtta
agctccgtcctcgaatatgaaggcggcgaacgcgcgcaatacctcttggaaaacctggtc
aaatactgccgcgacaagggcgtacgtatgccacacggcacgaccaccccgtatttgaat
accgtttcggttgaaaacgaaaaaggcattccgggcgaccaaaacatcgaacaccgcatc
cgcgcattcgtgcgctggaacgccgccgccatcgtattgcgcgccggcaagaaagatttg
gaactgggtgggcacatcgcatctttccaatctgccgccaccatgtacgaagtcggtttc
aaccacttttggaaagccaaaggcgaaggcgaagaaggcgatttggtcttcttccaaggt
cacgtcgccccgggcatctatgcacgcgcattcgtcgagggccgtctgaccgaagaccag
ctgaacaacttccgccaagaagtggacggacacggtctgccttcctatccgcacccccac
ctcttgcccgacttttggcagttcccgaccgtatccatgggcttggggcccatcatggcg
atttatcaggcgcgtttcctgaaatacttggaatcgcgtggtttggcaaaaaccaaaggc
cgtaaagtatggtgtttctgcggcgacggcgaaatggacgaacccgaatctcaaggtgca
atcgcactggctgcacgcgaaggcttggacaacctgattttcgtcatcaactgcaacctg
caacgcttggacggtccggtacgcggcaacggcaaaatcatccaagaattggaaggcaac
tttgccggcgccggctggaatgtcgtcaaagtcatttggggccgccgctgggaccgcctc
ttggcgaaagacaaagacggtatcctgcgccaacgtatggaagaatgtttggacggcgac
taccaaacttacaaatccaaagacggcgcgtatgtgcgcgaacacttcttcaatacgccc
gaactgaaaacattggttgccgatatgaccgatgagcaactctgggcattgaaccgcggc
ggccacgacccgcaaaaagtgtacaacgcctacgaccgcgcagcgaaccatgccgacggc
aaacctaccgtcatcttggcgaaaaccattaaaggttacggtatgggcgcatccggcgaa
ggtcagaacgttgcccaccaagccaaaaaaatggacaaagcgtccctgaaacaattccgc
gaccgctttgacattccggttaccgacgaacaaatcgaaagcggcgatctgccttacctg
acttttgcccccgatacggaagaatacaaatacctgcacgcacgccgcgatgctttgggt
ggctacctgccgcaacgcaaaccgacgcaggaagtattggaagtgcccgagctgtcagca
ttcgacgcacaactcaaatccagcggtgaacgcgagttctcgaccacgatggcattcgtc
cgcatcctgtccactttgctgaaagacaaaaaaatcggcaaacgcgtcgtacctatcgtt
cccgacgaaagccgtactttcggcatggaaggtatgttccgccaatacggtatttggaat
ccgaaaggtcagcaatatacccctcaagacaaagaccaactgatgttctataaagaatcc
gttgacggtcaaatcttgcaagaaggtattaacgaaccgggcgcgatggccgactggatt
gcggctgcaaccagctacgccaacagcaacttcgcgatgattccgttctacatttactat
tctatgttcggtttccaacgtgtcggcgacttggcatgggcagccggtgatatgcacgcg
cgcggcttcctgctgggcggtactgccggccgtacgacgctgaacggcgaaggcctgcaa
cacgaagacggccacagccacatccaggccgacctgattccgaactgcgtatcttatgac
ccgactttccaatacgaagtcgccgtcatcgtacaagacggtctgcgccgtatgtatgcc
aataatgaagacgtgttctactacatcaccctgatgaacgagaactacacccatccggat
atgcccgaaggtgcggaacaagacatcctgaaaggtatgtatctgctgaaagccggcggc
aaaggcgacaagaaagttcaattgatgggctccggtaccatcctgcaagaagtcattgcc
ggtgccgagctgctgaaagccgacttcggcgtagaagcagacatctggtcttgcccgtcc
ttcaacctgctgcaccgcgacgctgtcgaggtagaacgcttcaaccgcctgcatccgctg
gaagccgaaaaagtacctttcgttacttcccaactgcaaggtcatgacggtccggtgatt
gccgctaccgactatatccgcagctatgctgaccgtatccgcgcctacatcccgaacgac
taccacgtcttgggcactgacggtttcggccgttccgacagtcgcgccaacctgcgccgc
ttctttgaagtggatcgctacaacgttgccgtggccgcattggccgcattggcggaacaa
ggcaaagtcagcaaagaaaccgttcaacaagccattgagaaatacggcatcaaagccgat
tcagctcctagctggaaacgctga
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