Actinomadura parvosata subsp. kistnae: BKM31_52685
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Entry
BKM31_52685 CDS
T04759
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
noa
Actinomadura parvosata subsp. kistnae
Pathway
noa00020
Citrate cycle (TCA cycle)
noa00630
Glyoxylate and dicarboxylate metabolism
noa00785
Lipoic acid metabolism
noa01100
Metabolic pathways
noa01110
Biosynthesis of secondary metabolites
noa01120
Microbial metabolism in diverse environments
noa01200
Carbon metabolism
noa01210
2-Oxocarboxylic acid metabolism
Module
noa_M00009
Citrate cycle (TCA cycle, Krebs cycle)
noa_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
noa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
BKM31_52685 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
BKM31_52685 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
BKM31_52685 (kgd)
Enzymes [BR:
noa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
BKM31_52685 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
BKM31_52685 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
BKM31_52685 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
BKM31_52685 (kgd)
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AQZ68984
UniProt:
A0A1V0AFH1
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All DBs
Position
complement(11670798..11674445)
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AA seq
1215 aa
AA seq
DB search
MSSESSRTNPLASFGQNEWLVDELYQKYLQDPESVDKAWWNFFADYNPDYGPGRTPVREA
ANGTVTAPAPPQTPKAPPKAPPAAEKPKQPATPVPKGAEEVKLRGAAARTAANMDLSLAV
PTATSVRAIPAKLLIDNRIVINNHLKRGRGGKVSFTHLIGFAIVKALKAMPEMNYSYAEI
DGKPTLVKPEHVGFGLAIDVQKSNGERQLLVPSIKGAEEMDFRQFWMAYEEVVRKARAGK
LGVDDFSGTTISLTNPGTIGTVHSVPRLMPGQGTIIGVGAMEYPAEYQGASPDTLSRLAV
SKVMTLTSTYDHRIIQGAQSGDFLRQIHRLLLGEDGFYDEIFEALRIPYEPVRWVQDISA
THDDDVAKSARVIELIHAYRVRGHLMAETDPLEYKQRKHPDLDIQSHGLTLWDLEREFAT
GGFGGKPLMKLRDILGVLRDSYCRTVGIEYMHIQNPEERAWIQARVEKPHKSPERDEQLN
ILSRLNTAEAFETFLQTKFVGQKRFSLEGGESLIPLLDSVISDAADEGLDEVVIGMAHRG
RLNVLANIVGKSYAQIFGEFEGNIDPRTAHGSGDVKYHLGATGTFTAPSGKTITASVVAN
PSHLEAVDPVLEGVVRAKQDLLERGEEGFTVLPVLIHGDAAFAGQGVVAETLNLSQLRGY
RTGGTVHVVVNNQVGFTTSPASSRSSVYATDVARMIQAPIFHVNGDDPEAVVRVGELAYE
YRQAFRKDVVIDLICYRRRGHNEGDNPAFTQPLMYDLIDAKRSTRKLYTEALIGRGDITV
EEAESALRDYQAKLEQAFTETREAAKKPAEAAAMRVPPTEVVKWSHDDTPTGITHETLKR
IVDTQLNLPEGFTPHPRLAPVLQRRGQMVEQDAIDWAMGETLAFGSLLMDGHPVRLVGQD
SRRGTFTQRHAVLVDRMTGADHTPLKTFNQGTTKFYVYDSLLSEFAALGFEYGYSVVRPD
ALVCWEAQFGDFVNGAQTIIDEFISSGEQKWGQKSSVVLLLPHGYEGQGPDHSSARIERF
LQVCALDNMTVAQPTTPANYFHLLRWQVESERHKPLVVFTPKSLLRHKAATSKASDFTSG
SFQPVLGDATADPAKVTKVVLTSGRLYYDLAARRDKDGRDDVAIVRLERLYPFPSEELAA
ELSRYGDQVELIWAQDEPANMGPWPYLTLKMAEDPQTLGGRAVRRVSRTPNSSPATGSHN
SHDTELEEILHQIFG
NT seq
3648 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctgagtcgtcgcggacaaacccgctggcaagctttggtcagaacgagtggctt
gtcgacgagctgtaccagaagtacctccaagatccagagtctgtcgacaaggcctggtgg
aacttcttcgctgactacaaccctgattacggaccgggccgaaccccggtcagggaggcg
gcgaacggcacggtgaccgcgcccgctcctccccagaccccgaaggcgccacccaaggcg
ccacccgcggccgaaaagccgaagcagcccgccaccccggtgcccaagggcgccgaggag
gtcaagctgcgcggcgccgcggcccgcaccgccgccaacatggacctctcccttgcggtc
ccgacggcgaccagcgtgcgggccatcccggccaagctgctcatcgacaaccgcattgtg
atcaacaatcacctcaagcggggccgcggcggcaaggtctccttcacgcacctgatcggg
ttcgcgatcgtcaaggcgctgaaggccatgccggagatgaactactcctacgccgagatc
gacggcaagccgacgctcgtcaagcccgagcacgtcggcttcggcctcgcgatcgacgtc
cagaagagcaacggcgagcgccagctcctcgtgccctccatcaagggcgccgaggagatg
gacttccgccagttctggatggcctatgaggaggtcgtccgcaaggcccgcgccggcaag
ctcggcgtcgacgacttctccggcaccacgatctccctcaccaaccccggcacgatcggc
accgtccactccgtgccgcgcctcatgcccggccagggcacgatcatcggcgtcggcgcg
atggaatacccggccgaataccagggggcctcccccgacacgctctcgcgcctggccgtc
tccaaggtcatgacgctgaccagcacctacgaccaccggatcatccagggcgcccagtcg
ggcgacttcctgcgccagatccaccggctgctgctcggcgaggacggcttctacgacgag
atcttcgaggcgctgcggatcccgtacgagccggtccgctgggtccaggacatctcggcc
acccacgacgacgacgtggccaagtccgcgcgcgtgatcgagctgatccacgcctaccgc
gtccgcggccacctgatggccgagacggacccgctggagtacaagcagcgcaagcacccc
gacctcgacatccagtcgcacggcctgacgctgtgggacctcgagcgcgagttcgcgacg
ggcggcttcggcggcaagccgctgatgaagctgcgcgacatcctgggcgtgctgcgtgac
tcctactgccgcaccgtcggcatcgagtacatgcacatccagaaccccgaggagagggcc
tggatccaggcgcgggtggagaagccgcacaagtcgcccgagcgcgacgagcagctcaac
atcctgtcccggctcaacaccgccgaggcgttcgagacgttcctgcagacgaagttcgtc
ggccagaagcgcttctcgctggagggcggcgagtccctgatcccgctgctcgactccgtg
atcagcgacgccgccgacgagggcctcgacgaggtcgtcatcggcatggcgcaccgcggc
cgcctcaacgtcctggccaacatcgtgggcaagtcctacgcccagatcttcggcgagttc
gagggcaacatcgacccgcgcacggcgcacggctccggcgacgtgaagtaccacctcggc
gccaccggcacgttcaccgcgccgagcggcaagacgatcaccgcgtccgtggtcgccaac
ccctcccacctggaggcggtcgacccggtcctggagggcgtcgtccgcgcgaagcaggac
cttcttgagcgcggcgaggagggcttcaccgtcctgcccgtcctcatccacggcgacgcg
gccttcgccggccagggcgtcgtggccgagaccctcaacctgtcgcagctgcgcggctac
cgcaccggcggcaccgtgcacgtggtcgtcaacaaccaggtcggcttcaccacctcgccc
gcctcctcccgctcctcggtctacgcgaccgacgtggcgcggatgatccaggcgccgatc
ttccacgtcaacggcgacgaccccgaggccgtggtccgcgtgggcgaactggcctacgag
taccgccaggcgttccgcaaggacgtcgtcatcgacctcatctgctaccgccgccgcggc
cacaacgagggcgacaaccccgccttcacccagccgctgatgtacgacctgatcgacgcc
aagcgctccacccgcaagctctacaccgaggcgctgatcggccggggcgacatcacggtc
gaggaggccgagtccgcgctgcgcgactaccaggccaagctggagcaggcgttcaccgag
acgcgcgaggcggcgaagaagccggccgaggcggccgcgatgcgggtgcccccgaccgag
gtcgtcaagtggtcccacgacgacacgccgaccggcatcacgcacgagacgctcaagcgc
atcgtcgacacccagctcaacctccccgagggcttcacgccgcacccgcgcctggcgccg
gtgctgcagcgccgcggccagatggtcgagcaggacgcgatcgactgggcgatgggcgag
acgctggccttcggctcgctgctgatggacggccacccggtccgcctcgtcggacaggac
tcccggcgcggcacgttcacccagcgccacgccgtcctggtcgaccgcatgaccggcgcc
gaccacacgccgctcaagaccttcaaccagggcaccacgaagttctacgtctacgactcg
ctgctgagcgagttcgcggcgctcggcttcgagtacggctacagcgtcgtccgtcctgac
gccctggtctgctgggaggcgcagttcggcgacttcgtcaacggcgcccagacgatcatc
gacgagttcatctcgtcgggcgagcagaagtggggccagaagtcctccgtcgtgctgctg
ctgccgcacggctacgagggccagggccccgaccactcctcggcccgcatcgagcgtttc
ctccaggtctgcgcgctcgacaacatgacggtcgcgcagcccaccaccccggccaactac
ttccacctgctgcgctggcaggtggagtcggagcggcacaagccgctggtggtcttcacg
cccaagtcgctgctgcgccacaaggcggccacgtcgaaggcgtccgacttcacctcgggc
tccttccagccggtcctgggcgacgccacggccgacccggccaaggtcaccaaggtcgtg
ctcacctccggcaggctctactacgacctggcggcgcggcgcgacaaggacggccgcgac
gacgtcgcgatcgtgcggctggagcgcctctacccgttcccgtccgaggagctcgccgcc
gagctgtcccggtacggcgaccaggtggagctgatctgggcgcaggacgagccggccaac
atgggcccgtggccgtacctcacgctcaagatggccgaagacccgcagacgctgggcggc
cgggcggtgcggcgcgtgtcgcgcacgcccaacagctcgccggcgaccgggtcgcacaac
tcccacgacacggagctcgaggagatcctgcaccagatcttcggctga
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