Nyctereutes procyonoides (raccoon dog): 129498939 Help Entry 129498939         CDS       T09008                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism npo  Nyctereutes procyonoides (raccoon dog) Pathway npo00230   Purine metabolism npo01100   Metabolic pathways npo01522   Endocrine resistance npo04015   Rap1 signaling pathway npo04020   Calcium signaling pathway npo04022   cGMP-PKG signaling pathway npo04024   cAMP signaling pathway npo04062   Chemokine signaling pathway npo04072   Phospholipase D signaling pathway npo04081   Hormone signaling npo04082   Neuroactive ligand signaling npo04114   Oocyte meiosis npo04211   Longevity regulating pathway npo04213   Longevity regulating pathway - multiple species npo04261   Adrenergic signaling in cardiomyocytes npo04270   Vascular smooth muscle contraction npo04371   Apelin signaling pathway npo04540   Gap junction npo04611   Platelet activation npo04713   Circadian entrainment npo04714   Thermogenesis npo04723   Retrograde endocannabinoid signaling npo04724   Glutamatergic synapse npo04725   Cholinergic synapse npo04727   GABAergic synapse npo04750   Inflammatory mediator regulation of TRP channels npo04911   Insulin secretion npo04912   GnRH signaling pathway npo04913   Ovarian steroidogenesis npo04914   Progesterone-mediated oocyte maturation npo04915   Estrogen signaling pathway npo04916   Melanogenesis npo04918   Thyroid hormone synthesis npo04921   Oxytocin signaling pathway npo04922   Glucagon signaling pathway npo04923   Regulation of lipolysis in adipocytes npo04925   Aldosterone synthesis and secretion npo04926   Relaxin signaling pathway npo04927   Cortisol synthesis and secretion npo04928   Parathyroid hormone synthesis, secretion and action npo04934   Cushing syndrome npo04935   Growth hormone synthesis, secretion and action npo04970   Salivary secretion npo04971   Gastric acid secretion npo04972   Pancreatic secretion npo04976   Bile secretion npo05032   Morphine addiction npo05163   Human cytomegalovirus infection npo05166   Human T-cell leukemia virus 1 infection npo05200   Pathways in cancer npo05207   Chemical carcinogenesis - receptor activation npo05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:npo00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     129498939 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     129498939 (ADCY2)    04371 Apelin signaling pathway     129498939 (ADCY2)    04020 Calcium signaling pathway     129498939 (ADCY2)    04072 Phospholipase D signaling pathway     129498939 (ADCY2)    04024 cAMP signaling pathway     129498939 (ADCY2)    04022 cGMP-PKG signaling pathway     129498939 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     129498939 (ADCY2)    04081 Hormone signaling     129498939 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     129498939 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     129498939 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     129498939 (ADCY2)    04062 Chemokine signaling pathway     129498939 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     129498939 (ADCY2)    04922 Glucagon signaling pathway     129498939 (ADCY2)    04923 Regulation of lipolysis in adipocytes     129498939 (ADCY2)    04912 GnRH signaling pathway     129498939 (ADCY2)    04913 Ovarian steroidogenesis     129498939 (ADCY2)    04915 Estrogen signaling pathway     129498939 (ADCY2)    04914 Progesterone-mediated oocyte maturation     129498939 (ADCY2)    04921 Oxytocin signaling pathway     129498939 (ADCY2)    04926 Relaxin signaling pathway     129498939 (ADCY2)    04935 Growth hormone synthesis, secretion and action     129498939 (ADCY2)    04918 Thyroid hormone synthesis     129498939 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     129498939 (ADCY2)    04916 Melanogenesis     129498939 (ADCY2)    04925 Aldosterone synthesis and secretion     129498939 (ADCY2)    04927 Cortisol synthesis and secretion     129498939 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     129498939 (ADCY2)    04270 Vascular smooth muscle contraction     129498939 (ADCY2)   09154 Digestive system    04970 Salivary secretion     129498939 (ADCY2)    04971 Gastric acid secretion     129498939 (ADCY2)    04972 Pancreatic secretion     129498939 (ADCY2)    04976 Bile secretion     129498939 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     129498939 (ADCY2)    04727 GABAergic synapse     129498939 (ADCY2)    04725 Cholinergic synapse     129498939 (ADCY2)    04723 Retrograde endocannabinoid signaling     129498939 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     129498939 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     129498939 (ADCY2)    04213 Longevity regulating pathway - multiple species     129498939 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     129498939 (ADCY2)    04714 Thermogenesis     129498939 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     129498939 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     129498939 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     129498939 (ADCY2)    05163 Human cytomegalovirus infection     129498939 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     129498939 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     129498939 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     129498939 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     129498939 (ADCY2) Enzymes [BR:npo01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      129498939 (ADCY2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  129498939 NCBI-ProteinID:  XP_055164527 LinkDB All DBs Position Unknown AA seq 1096 aa AA seqDB search MWREAMRRRRYLRDRGEAAAAAAAAGGGGGGLQRSRDWLYESYYCMSQQHPLIVFLLLIV MGACLALLAVFFALRLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIW ICLVAMGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSASHTIVLS VCLSATPGAKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLE FEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYA DIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNH AKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLAN HMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPH LFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNF QNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKILEKEYRAT ALPAFKYYVTCACLIFFCIFIVQILVLPKTSILGISFGAAFLLLAFILFICFAGQLLQCS KKASASLLWLLKSSGIIADRPWPRVSLTVLTTAIILTMAVFNMFFLSDPEETIPPTANTS NMSLSALSNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVAYNT ILLHTHAHVLDDYSQVLFERPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCRLDFLWK NKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLYHQSYDCVCVMFASIPD FKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVP SQEHAQEPERQYMHIGTMVEFAFALVAKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQK PQYDIWGNTVNVASRMDSTGVLDKIQVTEETSVILQTLGYACTCRGIINVKGKGELKTYF VNTEMSRSLSQSNLAS NT seq 3291 nt NT seq  +upstreamnt  +downstreamnt atgtggcgggaggcgatgcggcgccgccgctacctgcgggaccgcggcgaggcggcggcg gcggcggcggcggcgggcggcggcggcggcgggctgcagcggtcccgggactggctgtac gagtcctactactgcatgagccagcagcacccgctcatcgtcttcctgctgctcatcgtc atgggcgcctgcctcgccctgctcgccgtcttcttcgcgctccggctggaagttgaagac cacgtggcgtttttaataacggtcccgacggccctggcgattttctttgcaatattcatc ctcgtctgcatcgagtctgtgttcaaaaagctgctccgccttttctccttggtgatatgg atatgtctcgtggccatggggtacctcttcatgtgctttggaggcaccgtctctccctgg gaccaggtgtcattcttcctcttcatcatcttcgtggtgtacaccatgctgcccttcaac atgcgagatgccatcatcgccagcgtgctcacctccgcctcccacaccatcgtgctgagc gtctgcctgtccgcgacgccgggggccaaggagcacctggtctggcagatcctggccaat gtgatcattttcatctgtgggaacctggcgggggcataccacaaacacctcatggaactt gccctgcagcagacatatcaggacacatgcaattgcatcaagtcccggatcaagctggaa tttgaaaagcgtcagcaggaacggcttttgctctctctgctgcctgctcacatagccatg gaaatgaaagctgagatcatccagaggcttcagggccccaaagccggccaaatggaaaac acaaacaactttcacaacctgtatgtcaagcgacacaccaacgtgagtatcctgtatgct gacattgttggcttcacccggctggccagtgactgctccccaggagagctggtccacatg ctgaacgagctgtttggaaagtttgatcaaattgcaaaggagaatgaatgcatgagaata aaaattttgggagactgctactattgtgtatccggactccctatatctctcccaaaccat gccaagaactgtgtgaaaatggggctggacatgtgtgaagccataaagaaggtgagggat gcgactggtgtggatattaacatgcgcgtgggagtgcattccgggaacgtcctttgcggg gtgatcggcctgcagaagtggcagtacgacgtgtggtcacatgacgtgaccctggccaat cacatggaggctggaggggtccctggacgtgttcacatttcttctgtcaccctggaacac ttgaacggtgcttataaagtggaggaaggagacggtgacatcagagacccgtatttaaag cagcacctggtgaagacctactttgtaatcaaccccaagggagaacgaaggagtcctcac ctcttcagacctcgccacaccctcgatggagccaagatgagggcttccgttcgcatgacc cggtacctggagtcctggggagcggccaagccctttgcacacctgcatcatcgagacagc atgaccacagagaatggcaagatcagcacgacggatgtgccaatgggtcagcataatttc caaaatcgtaccttaagaaccaagtcccaaaagaaaagatttgaagaagaattaaatgaa aggatgattcaagcaattgatggaattaatgcacaaaagcagtggctcaagtctgaagac attcagagaatctcactcctgttctacaataaaatactagaaaaagaataccgagccact gcactgccagcgtttaagtactacgtcacctgcgcctgtctcatattcttctgcatcttt attgtacagattctggtattaccaaaaacatcgattctggggatctcctttggagctgca tttctcctgctcgcctttatccttttcatctgctttgctggacagcttttgcaatgcagc aagaaggcatctgcctctctcctgtggctgttgaagtcgtcgggcatcatcgccgaccgg ccctggccgcgggtctccctcaccgtcctcaccacggccatcattctgaccatggccgtg ttcaacatgtttttcctgagtgatccagaggaaacaattcctccaactgccaatacatca aacatgagtctgtctgccttaagtaatcaggcagcgattctgcgtgcacaaaatctgttt ttcctcccgtactttatctacagctgcattctgggtttgatttcctgctcggtgttcctg cgggtgaattacgagttgaaaatgttgatcatgatggtggcattggtggcctacaacacc atcctcctgcacactcacgcccacgtcctggacgactacagccaggtcttattcgagaga ccaggcatttggaaagacctgaagaccatgggctcagtgtctctctttatattcttcatc acactgcttgttctgggtagacagaatgaatattactgtaggttagacttcttatggaag aacaaattcaaaaaagaacgggaggagatagagaccatggagaacctgaaccgtgtgctg ctggagaacgtgctgcccgcacatgtggccgagcatttcctggcccggagcctgaagaat gaggacttataccaccaatcctatgactgtgtctgcgtcatgtttgcctccattccggat ttcaaagaattctacacagaatcagatgtgaacaaggagggtttggaatgccttcggctc ctgaatgagatcatcgccgactttgatgatctgctgtccaagccaaaattcagtggagtt gaaaagatcaagaccattggcagcacatacatggcagcgaccggtctgagcgccgtgcct agccaggagcatgcccaggagcccgagaggcagtacatgcacattggcaccatggtggag tttgcctttgccctggtggcgaaactggatgctatcaacaagcactccttcaatgacttc aagttgcgagtgggtattaaccatggacctgtaatagctggtgtgattggagcccagaag ccacagtatgatatctggggtaacacggtgaacgtggccagcaggatggacagcaccggc gtgctggacaaaatacaggtcaccgaggagaccagcgtcatccttcagaccctggggtac gcatgcacgtgtcgagggataatcaacgtgaaaggcaagggggagctgaagacgtacttt gtaaacacggaaatgtcaaggtccctttcccagagcaacttggcatcctga

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