Nyctereutes procyonoides (raccoon dog): 129513760 Help Entry 129513760         CDS       T09008                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism npo  Nyctereutes procyonoides (raccoon dog) Pathway npo04064   NF-kappa B signaling pathway npo04380   Osteoclast differentiation npo04650   Natural killer cell mediated cytotoxicity npo04658   Th1 and Th2 cell differentiation npo04659   Th17 cell differentiation npo04660   T cell receptor signaling pathway npo05135   Yersinia infection npo05166   Human T-cell leukemia virus 1 infection npo05235   PD-L1 expression and PD-1 checkpoint pathway in cancer npo05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:npo00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     129513760 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     129513760 (LCK)    04660 T cell receptor signaling pathway     129513760 (LCK)    04658 Th1 and Th2 cell differentiation     129513760 (LCK)    04659 Th17 cell differentiation     129513760 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     129513760 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     129513760 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     129513760 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     129513760 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     129513760 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:npo01001]     129513760 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:npo03036]     129513760 (LCK) Enzymes [BR:npo01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      129513760 (LCK) Protein kinases [BR:npo01001]  Non-receptor tyrosine kinases   SRC family    129513760 (LCK) Chromosome and associated proteins [BR:npo03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     129513760 (LCK) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH2_1 Haspin_kinase SH3_16 SH3_3 Motif Other DBs NCBI-GeneID:  129513760 NCBI-ProteinID:  XP_055188036 LinkDB All DBs Position Unknown AA seq 509 aa AA seqDB search MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKATLPMRNGSDVRDPLVIYEGSNPPASP LQDNLVIALHSYEPSHDGDLGFEKGEQLRILERNGEWWKAQSLTTGQEGFIPFNFVAKAN SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH YKIRNLDKGGFYISPRITFPDLHELVRYYTNSSDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTPPGIKLTINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMMLCWKER PEDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtagctgcagctcaaaccctgaagatgactggatggaaaacatcgatgtatgt gaaaactgccattaccccatagtcccactggatggcaaggccacgctgcccatgcggaat ggctctgacgtgcgggatccactggttatctacgaaggctccaatcccccagcctcacca ctgcaagacaacctggttatcgctctgcacagctatgagccctctcacgatggagacttg ggtttcgagaagggtgaacagctccgtatcctggagcggaacggtgagtggtggaaggcg cagtccttgaccacgggccaggaaggcttcatccctttcaatttcgtggccaaagcgaac agcctggagcccgaaccctggttcttcaagaacctgagccgcaaggacgcggaacggcag ctcctggcgcccgggaacactcacggctccttcctgattcgggagagcgagagcaccgcg ggatcgttttcattgtctgtgcgggacttcgaccagaaccagggagaggtggtgaaacat tacaagatccgtaacctggacaaaggcggcttctacatctcccctcgcatcacttttcct gacctgcacgagctggtccgctattacaccaattcttcggacgggctgtgtacacggttg agtcgcccctgccagacccagaagccccagaagccttggtgggaggatgagtgggaggtt cccagggagacgctgaagctggtggagcggctaggggccggccagttcggggaggtgtgg atggggtactacaacgggcacacaaaggtggcagtgaagagcctgaagcagggcagcatg tcccctgacgccttcctggccgaggctaatctcatgaagcagctgcagcaccagaggctg gtccggctctatgcggtggtcacccaggagcccatctacatcatcacggaatacatggag aacgggagcctggtggatttcctcaagacccccccaggcatcaagctgactatcaacaaa ctcttggacatggcagcccaaattgcagagggcatggcattcattgaagagcggaattat atccaccgtgacctgagggctgccaatatcctggtgtctgacaccctgagctgcaagatc gcagactttggcctggcacgccttatcgaggacaacgagtacacagcaagggagggagcc aagtttcccattaagtggacagcaccagaagccattaactacgggacattcaccatcaag tcggacgtgtggtcttttgggatcctgctgacagagattgtcacccatggccgcatccct tacccagggatgaccaatcctgaggtgattcagaacctggaacgaggctaccgcatggtg cgacctgacaactgtccagaggagctataccaactcatgatgctgtgttggaaggagcgc ccagaggatcggcccacctttgactacctgcgtagtgtgctggaggacttcttcacagcc acagagggccagtaccagccccagccctga

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