Nyctereutes procyonoides (raccoon dog): 129523419 Help Entry 129523419         CDS       T09008                                  Symbol IRS1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism npo  Nyctereutes procyonoides (raccoon dog) Pathway npo04022   cGMP-PKG signaling pathway npo04068   FoxO signaling pathway npo04081   Hormone signaling npo04140   Autophagy - animal npo04150   mTOR signaling pathway npo04151   PI3K-Akt signaling pathway npo04152   AMPK signaling pathway npo04211   Longevity regulating pathway npo04213   Longevity regulating pathway - multiple species npo04722   Neurotrophin signaling pathway npo04910   Insulin signaling pathway npo04920   Adipocytokine signaling pathway npo04923   Regulation of lipolysis in adipocytes npo04930   Type II diabetes mellitus npo04931   Insulin resistance npo04932   Non-alcoholic fatty liver disease npo04935   Growth hormone synthesis, secretion and action npo04960   Aldosterone-regulated sodium reabsorption npo05010   Alzheimer disease npo05206   MicroRNAs in cancer npo05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:npo00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     129523419 (IRS1)    04022 cGMP-PKG signaling pathway     129523419 (IRS1)    04151 PI3K-Akt signaling pathway     129523419 (IRS1)    04152 AMPK signaling pathway     129523419 (IRS1)    04150 mTOR signaling pathway     129523419 (IRS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     129523419 (IRS1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     129523419 (IRS1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     129523419 (IRS1)    04923 Regulation of lipolysis in adipocytes     129523419 (IRS1)    04920 Adipocytokine signaling pathway     129523419 (IRS1)    04935 Growth hormone synthesis, secretion and action     129523419 (IRS1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     129523419 (IRS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     129523419 (IRS1)   09149 Aging    04211 Longevity regulating pathway     129523419 (IRS1)    04213 Longevity regulating pathway - multiple species     129523419 (IRS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     129523419 (IRS1)   09164 Neurodegenerative disease    05010 Alzheimer disease     129523419 (IRS1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     129523419 (IRS1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     129523419 (IRS1)    04932 Non-alcoholic fatty liver disease     129523419 (IRS1)    04931 Insulin resistance     129523419 (IRS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  129523419 NCBI-ProteinID:  XP_055202311 LinkDB All DBs Position Unknown AA seq 1239 aa AA seqDB search MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HDGASAPGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT RRSRTESITATSPASVVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTTRTHAHRHR GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGSSTLTAPN GHYILPRGGNGHRYIPGAGLGTSPALAADEAAGAADLDNRFRKRTHSAGTSPTISHQKTP SQSSVASIEEYTEMMPAYPPGGGSGGRLPGYRHSAFVPTHSYPEEGLDMHPLDRRGGHHR PDAAALHTDDGYMPMSPGVAPVPSSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN GYMMMSPSGSCSPDIGGGPGSSGSGSAAPSGSSYGKLWTNGVGGHHPHALPHPKLPVESG SGKLLSCTGDYMNMSPVGDSNTSSPSDGYYGPEDPQHKPVLSYYSLPRSFKHTQRPGELE ESARHQHLRLSSSSGRLLYAATAEDSSSSTSSDSLGGGYCGVRPDPGLPHIHHQVLQPHL PRKVDTAAQTNSRLARPTRLSLGDPKASTLPRVREQQHPPPLLHPPEPKSPGEYVNIEFG SDQPGYLSGPMAARSSPSVRCPPQLQPAPREEETGTEEYMNMDLGPGRRAAWQEGAGVQP GRVGPAPPGAASVCRPTRAVPSSRGDYMTMQVGCPGQGYVDTSPVAPISYADMRTGIVVE EASLPGATAAAPSSSSAASASPTAPPKAGELVARSSLLGGPQGPGGMSAFTRVNLSPNRN QSAKVIRADPQGCRRRHSSETFSSTPSATRAGNAVPFGGGAALGGSGGGSSAEDMKRHSS ASFENVWLRPGELGGAPKEPAPHAGAAGGLENGLNYIDLDLVKDFKQRSQERPPQPQPPP PPAPHQPLGSSESSSTSRSSEDLSAYASISFQKQPEDLQ NT seq 3720 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctccggagaccgacggcttctcggacgtgcgcaaggtgggctacctgcgc aaacccaagagcatgcacaagcgcttcttcgtgctgcgggcggccagcgaggcggggggc ccggcgcgcctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc aaacgctcgatccccctcgagagctgcttcaacatcaacaagcgggcggactccaagaac aagcacctggtggccctttacacccgggacgagcactttgccatcgcggcggacagcgag gccgagcaggacagctggtaccaggccctcctgcagctgcacaaccgggccaagggccac cacgacggcgcctcggcccccggggcgggaggcggcgggggcagctgcagcggcagctcg ggcctcggggaggccggcgaggacttgagctacggcgacgtgcccccgggacctgcgttc aaggaggtctggcaggtgatcctgaaacccaagggcctggggcagacaaagaacctgatt ggcatctaccgcctctgcctgaccagcaagaccatcagcttcgtgaagctgaactccgag gcggcggccgtggtgctgcagctgatgaacatccggcgttgcggccactcggagaacttc ttcttcatcgaagtgggccgttccgcggtgacgggacccggcgagttctggatgcaggtg gatgactccgtggtggcccagaacatgcacgagaccatcctggaggccatgcgggccatg agcgacgagttccgccctcggagtaagagccagtcctcctccaactgctccaaccccatc agcgtccccctgcgccggcaccacctcaacaaccccccacccagccaggtggggctgacg cgccgctcgcgcaccgagagcatcaccgccacctctccggccagcgtggtgggcgggaag cagggctccttccgtgtgcgcgcgtccagcgacggcgagggcaccatgtcccgcccggcc tcggtggacggcagccccgtgagcccgagcaccaccaggacccacgcgcaccggcaccgc ggcagctcccggctgcaccccccgctcaaccacagccgctccatccccatgccttcctcc cgctgctcgccttccgccaccagcccggtcagcctgtcgtccagcagcaccagtggccac ggctccacctcggactgcctcttcccccggcggtctagtgcctctgtgtcgggctccccc agcgacggtggcttcatctcctctgacgagtacggctccagtccctgcgatttccgaagc tccttccgcagtgtcaccccggattccctgggccacacccccccggcccgcggcgaggag gagctgagcaactacatctgcatgggaggcaaagggtcctccaccctcaccgcccccaac ggtcactacattttgcctcggggtggcaatggccaccgctacatcccgggggctggcttg ggcaccagcccggccctggctgcggatgaagcggccggggcggccgacctggacaaccgg ttccgaaagcggactcactctgcgggcacgtcccccaccatttcccaccagaagaccccg tcccagtcttccgtggcttccattgaggagtacacggagatgatgcctgcctacccgcca ggaggtggcagtggaggccgactgcctggctaccggcactctgccttcgtgcccacccac tcctaccccgaggagggtctggacatgcaccctctggacaggcgtgggggccaccaccgg ccggacgccgccgccctgcacacggatgatggctacatgcccatgtccccgggagtggca ccggtgcccagcagccggaagggcagtggggactatatgcccatgagccccaagagcgtg tccgcgccgcagcagatcatcaaccctattagacgccatccccagagggtggaccccaat ggctacatgatgatgtccccaagcggcagctgctctcctgacattggaggtgggcccggc agcagcggcagcggcagcgccgccccttctgggagcagctatggcaagctgtggacaaac ggggtagggggccaccaccctcacgccctgccgcaccccaaactccccgtggagagcggg agtggcaagctcctgtcttgtaccggcgactacatgaacatgtcgccggtgggggactcc aacaccagcagcccctccgacggctactacggcccagaggacccccagcacaagcccgtt ctctcctactactcattgccaaggtcctttaagcacacccagcgccctggggagctggag gagagcgcccggcaccagcacctccgcctctcctccagctcgggtcgtcttctctacgcc gcgacggcggaagattcctcttcctccaccagcagcgacagcctgggcgggggatactgt ggggtcaggccggatcccggcctcccgcatatccaccatcaggtcctgcagcctcacctg cctcggaaggtggacacggccgcgcagaccaacagccgcctggctcggcccacgaggctg tccctgggggaccccaaggccagcaccttacctcgggttcgagaacagcagcacccgccg cccctgctgcaccctccggagcccaagagccccggggaatatgtgaatattgagttcggg agcgatcagccgggctacttatcgggtcccatggctgcccgcagctcgccctctgtcagg tgcccaccccagctccagccagctccccgggaggaagagactggcaccgaggagtacatg aacatggacctggggcctggccggagggcagcctggcaggagggtgctggggtccagcca ggcagggtgggccccgcgccccccggggccgctagcgtgtgcaggcccacccgggcagtg cccagcagccgcggcgactacatgaccatgcaggtgggctgtcccggccagggctacgtg gacacctcgccagtggcccccatcagctacgctgacatgcggacaggcattgtcgtggag gaggccagcctgccgggggccacagcggccgccccctcctcgtcctcggcagcctcggct tcccccacggcgcctccaaaagcgggggagctggtggcccgctcctccctgctggggggc ccgcagggacctgggggcatgagcgccttcacccgggtgaacctcagtcccaaccgcaac cagagtgccaaagtgatccgcgccgacccgcaggggtgccggaggcggcatagctctgag accttctcctccacgcccagtgccacccgggcgggcaacgcggtgcccttcggcgggggg gcggccctggggggcagcggtggcggcagcagcgcggaggatatgaaacgccacagttcg gcttcctttgagaacgtgtggctgaggcctggggagctcgggggagcccccaaggagccg gccccgcacgctggggccgccgggggtttggagaatgggcttaactacatagacctggat ttggtcaaggacttcaaacagcgctctcaggagcgcccccctcaaccgcagccgcccccg cccccggcccctcatcagcctctgggcagcagtgagagcagctcaaccagccgctccagc gaggatctaagcgcctatgccagcatcagtttccagaagcagccagaggacctccagtag

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